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Cheap flights from San Diego to South America from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to South America departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:51 am - 6:15 am
SAN
-
BOG
19h 24m1 stop
Multiple Airlines Logo
7:05 am - 7:46 pm
BOG
-
SAN
15h 41m1 stop
$353Multiple Airlines
Sun, Jan 18 - Tue, Jan 27
Multiple Airlines Logo
7:35 am - 6:15 am
SAN
-
BOG
20h 40m1 stop
Multiple Airlines Logo
7:05 am - 8:00 pm
BOG
-
SAN
14h 55m1 stop
$354Multiple Airlines
Sat, Mar 14 - Sat, Mar 21
American Airlines Logo
10:25 pm - 1:30 pm
SAN
-
CTG
12h 05m1 stop
American Airlines Logo
2:30 pm - 11:09 pm
CTG
-
SAN
11h 39m1 stop
$516American Airlines
Sat, Jan 17 - Sat, Jan 24
United Airlines Logo
8:00 am - 11:00 pm
SAN
-
CTG
12h 00m2 stops
United Airlines Logo
6:25 am - 6:33 pm
CTG
-
SAN
15h 08m2 stops
$519United Airlines
Sun, Mar 1 - Wed, Mar 4
Delta Logo
10:30 pm - 2:17 pm
SAN
-
CTG
12h 47m1 stop
Delta Logo
3:32 pm - 9:58 am
CTG
-
SAN
21h 26m1 stop
$521Delta
Sun, Jan 18 - Sat, Jan 31
Copa Airlines Logo
8:16 pm - 3:40 pm
SAN
-
LIM
16h 24m1 stop
Copa Airlines Logo
7:00 am - 5:13 pm
LIM
-
SAN
13h 13m1 stop
$567Copa Airlines
Mon, Jan 12 - Mon, Feb 2
Delta Logo
6:30 am - 9:35 am
SAN
-
GRU
22h 05m1 stop
Delta Logo
11:45 pm - 8:36 pm
GRU
-
SAN
24h 51m1 stop
$600Delta
Tue, Mar 3 - Tue, Mar 24
American Airlines Logo
6:20 am - 10:10 am
SAN
-
GRU
22h 50m1 stop
American Airlines Logo
12:15 am - 12:27 pm
GRU
-
SAN
17h 12m1 stop
$603American Airlines
Sun, Feb 1 - Mon, Feb 9
United Airlines Logo
5:50 pm - 9:30 am
SAN
-
GRU
34h 40m1 stop
United Airlines Logo
9:30 pm - 11:50 am
GRU
-
SAN
18h 20m1 stop
$609United Airlines
Sat, Mar 7 - Wed, Mar 11
Copa Airlines Logo
9:18 pm - 8:50 pm
SAN
-
GRU
19h 32m1 stop
Copa Airlines Logo
2:00 am - 6:30 pm
GRU
-
SAN
20h 30m1 stop
$638Copa Airlines
Fri, Mar 20 - Sat, Mar 28

LATAM Airlines flights from San Diego to South America

Our best LATAM Airlines deals on San Diego to South America flight tickets
LATAM Airlines
Mar 9
SAN6:15 amSan Diego
11h 15m
1 stop
BOG7:30 pmBogotá El Dorado
Mar 11
BOG3:55 pmBogotá El Dorado
19h 55m
1 stop
SAN9:50 amSan Diego
$513
Find similar
LATAM Airlines
Mar 9
SAN7:55 pmSan Diego
18h 50m
2 stops
BOG4:45 pmBogotá El Dorado
Mar 11
BOG7:00 amBogotá El Dorado
18h 09m
2 stops
SAN11:09 pmSan Diego
$518
Find similar
LATAM Airlines
Mar 1
SAN10:30 pmSan Diego
12h 47m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Mar 4
CTG3:32 pmCartagena Rafael Nunez
21h 34m
1 stop
SAN10:06 amSan Diego
$529
Find similar

Copa Airlines flights from San Diego to South America

Our best Copa Airlines deals on San Diego to South America flight tickets
Copa Airlines
Mar 11
SAN9:18 pmSan Diego
11h 38m
1 stop
MDE10:56 amMedellín Jose Maria Cordova Intl
Mar 18
MDE6:25 amMedellín Jose Maria Cordova Intl
13h 49m
1 stop
SAN6:14 pmSan Diego
$521
Find similar
Copa Airlines
Jan 6
SAN8:16 pmSan Diego
14h 13m
1 stop
BOG1:29 pmBogotá El Dorado
Feb 16
BOG7:00 amBogotá El Dorado
13h 13m
1 stop
SAN5:13 pmSan Diego
$559
Find similar
Copa Airlines
Jan 12
SAN8:16 pmSan Diego
16h 24m
1 stop
LIM3:40 pmLima J Chavez Intl
Feb 2
LIM7:00 amLima J Chavez Intl
13h 13m
1 stop
SAN5:13 pmSan Diego
$567
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Sun 1/18

7:51 am-6:15 am

1 stop19h 24m

Bogotá El Dorado

Tue 1/27

7:05 am-7:46 pm

1 stop15h 41m

$353

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Sat 3/14

7:35 am-6:15 am

1 stop20h 40m

Bogotá El Dorado

Sat 3/21

7:05 am-8:00 pm

1 stop14h 55m

$354

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Sat 1/17

10:25 pm-1:30 pm

1 stop12h 05m

Cartagena Rafael Nunez

Sat 1/24

2:30 pm-11:09 pm

1 stop11h 39m

$516

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Sun 3/1

8:00 am-11:00 pm

2 stops12h 00m

Cartagena Rafael Nunez

Wed 3/4

6:25 am-6:33 pm

2 stops15h 08m

$519

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Sun 1/18

10:30 pm-2:17 pm

1 stop12h 47m

Cartagena Rafael Nunez

Sat 1/31

3:32 pm-9:58 am

1 stop21h 26m

$521

San DiegoLima

SAN - LIM

SANLIM

San Diego

Mon 1/12

8:16 pm-3:40 pm

1 stop16h 24m

Lima J Chavez Intl

Mon 2/2

7:00 am-5:13 pm

1 stop13h 13m

$567

San DiegoSao Paulo

SAN - GRU

SANGRU

San Diego

Tue 3/3

6:30 am-9:35 am

1 stop22h 05m

Sao Paulo Guarulhos Intl

Tue 3/24

11:45 pm-8:36 pm

1 stop24h 51m

$600

San DiegoSao Paulo

SAN - GRU

SANGRU

San Diego

Sun 2/1

6:20 am-10:10 am

1 stop22h 50m

Sao Paulo Guarulhos Intl

Mon 2/9

12:15 am-12:27 pm

1 stop17h 12m

$603

San DiegoSao Paulo

SAN - GRU

SANGRU

San Diego

Sat 3/7

5:50 pm-9:30 am

1 stop34h 40m

Sao Paulo Guarulhos Intl

Wed 3/11

9:30 pm-11:50 am

1 stop18h 20m

$609

San DiegoSao Paulo

SAN - GRU

SANGRU

San Diego

Fri 3/20

9:18 pm-8:50 pm

1 stop19h 32m

Sao Paulo Guarulhos Intl

Sat 3/28

2:00 am-6:30 pm

1 stop20h 30m

$638

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Diego to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from San Diego to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $613. If you aren’t able to travel during the month of October, then book flights to South America from San Diego during January instead. Flights to South America in January, while not as cheap as those in October, still average around $647.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from San Diego to South America is on a Monday when prices can be found for as low as $708. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to South America for around $873.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest San Diego to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $736. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $808 on average. Flights to South America from San Diego in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $758 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Diego for as low as $587 on momondo.

Can stopping save me money on San Diego to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a San Diego to South America flight.

Cheap San Diego to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to South America

Fastest flight time

8h 54m

Direct flights

None
The fastest flight from San Diego to South America takes 8h 54m
There are no direct flights from San Diego to South America. There are no popular flight routes from San Diego to South America.
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  • When did momondo last update prices for flights from San Diego Airport to South America?

    Prices for flights from San Diego Airport to South America were last updated today.

  • How many operators does momondo search for flights from San Diego Airport to South America?

  • How old do you have to be to fly from San Diego Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from San Diego to South America

Compare and see reviews for airlines that fly from San Diego to South America with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $342Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
DeltaPriceFrom $430Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $443Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $452Free CancellationRating
7.5
1,892 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $460Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
GOLPriceFrom $645Free CancellationRating
7.3
1,131 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to South America?

Finding the right flight to South America from San Diego is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from San Diego to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from San Diego with this policy.

How can momondo help me find flights from San Diego to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to South America.

I’m not ready to book a flight from San Diego to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $265
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Flights to Sao Paulofrom $423
Flights to Bogotáfrom $178
Flights to Rio de Janeirofrom $472
Flights to Medellínfrom $187
Flights to Santiagofrom $378
Flights to Cartagenafrom $166
Flights to Quitofrom $227
Flights to Cuscofrom $432
Flights to Guayaquilfrom $187
Flights to Califrom $180