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Cheap flights from San Antonio to Des Moines from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Des Moines departing on 6/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Antonio to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:51 pm - 1:31 pm
SAT
-
DSM
17h 40m
1 stop
Multiple Airlines Logo
6:44 pm - 4:13 pm
DSM
-
SAT
21h 29m
2 stops
$313Multiple Airlines
Tue, Jun 9 - Fri, Jun 12
United Airlines Logo
1:40 pm - 7:24 pm
SAT
-
DSM
5h 44m
1 stop
United Airlines Logo
5:50 am - 12:43 pm
DSM
-
SAT
6h 53m
1 stop
$330United Airlines
Tue, Aug 18 - Wed, Aug 19
Frontier Logo
7:51 pm - 1:31 pm
SAT
-
DSM
17h 40m
1 stop
Frontier Logo
2:16 pm - 6:56 pm
DSM
-
SAT
28h 40m
1 stop
$335Frontier
Tue, Jun 9 - Fri, Jun 12
Southwest Logo
11:00 am - 5:45 pm
SAT
-
DSM
6h 45m
1 stop
Southwest Logo
6:10 am - 2:35 pm
DSM
-
SAT
8h 25m
2 stops
$340Southwest
Tue, Aug 18 - Wed, Aug 19
Southwest Logo
12:55 pm - 9:00 pm
SAT
-
DSM
8h 05m
2 stops
Southwest Logo
6:10 am - 2:35 pm
DSM
-
SAT
8h 25m
2 stops
$345Southwest
Tue, Aug 18 - Wed, Aug 19
Delta Logo
2:27 pm - 10:32 pm
SAT
-
DSM
8h 05m
1 stop
Delta Logo
10:54 am - 5:13 pm
DSM
-
SAT
6h 19m
1 stop
$386Delta
Thu, Jun 4 - Sun, Jun 7
American Airlines Logo
9:17 am - 4:03 pm
SAT
-
DSM
6h 46m
1 stop
American Airlines Logo
5:30 am - 9:59 am
DSM
-
SAT
4h 29m
1 stop
$395American Airlines
Wed, Jun 17 - Sun, Jun 21
American Airlines Logo
5:35 pm - 11:57 pm
SAT
-
DSM
6h 22m
1 stop
American Airlines Logo
4:48 pm - 11:59 pm
DSM
-
SAT
7h 11m
1 stop
$396American Airlines
Fri, May 22 - Wed, May 27
Southwest Logo
6:10 am - 3:05 pm
SAT
-
DSM
8h 55m
2 stops
Southwest Logo
4:40 pm - 1:00 am
DSM
-
SAT
8h 20m
2 stops
$406Southwest
Tue, Jun 9 - Fri, Jun 12
Delta Logo
7:40 am - 1:34 pm
SAT
-
DSM
5h 54m
1 stop
Delta Logo
6:38 pm - 12:24 am
DSM
-
SAT
5h 46m
1 stop
$407Delta
Fri, Jul 31 - Mon, Aug 3

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United Airlines flights from San Antonio to Des Moines

Our best United Airlines deals on San Antonio to Des Moines flight tickets
United Airlines
Aug 18
SAT1:40 pmSan Antonio
5h 44m
1 stop
DSM7:24 pmDes Moines
Aug 19
DSM5:50 amDes Moines
6h 53m
1 stop
SAT12:43 pmSan Antonio
$330
United Airlines
Jun 2
SAT5:57 pmSan Antonio
4h 43m
1 stop
DSM10:40 pmDes Moines
Jun 3
DSM5:17 pmDes Moines
6h 38m
1 stop
SAT11:55 pmSan Antonio
$415
United Airlines
Jun 2
SAT8:53 amSan Antonio
7h 22m
1 stop
DSM4:15 pmDes Moines
Jun 3
DSM1:35 pmDes Moines
9h 07m
2 stops
SAT10:42 pmSan Antonio
$420

Southwest flights from San Antonio to Des Moines

Our best Southwest deals on San Antonio to Des Moines flight tickets
Southwest
Aug 18
SAT11:00 amSan Antonio
6h 45m
1 stop
DSM5:45 pmDes Moines
Aug 19
DSM6:10 amDes Moines
8h 25m
2 stops
SAT2:35 pmSan Antonio
$340
Southwest
Aug 18
SAT12:55 pmSan Antonio
8h 05m
2 stops
DSM9:00 pmDes Moines
Aug 19
DSM6:10 amDes Moines
8h 25m
2 stops
SAT2:35 pmSan Antonio
$345
Southwest
Jun 14
SAT6:50 amSan Antonio
4h 35m
1 stop
DSM11:25 amDes Moines
Jun 17
DSM3:45 pmDes Moines
7h 55m
1 stop
SAT11:40 pmSan Antonio
$371

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 6/9

7:51 pm-1:31 pm

1 stop17h 40m

Des Moines

Fri 6/12

6:44 pm-4:13 pm

2 stops21h 29m

$313

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 8/18

1:40 pm-7:24 pm

1 stop5h 44m

Des Moines

Wed 8/19

5:50 am-12:43 pm

1 stop6h 53m

$330

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 6/9

7:51 pm-1:31 pm

1 stop17h 40m

Des Moines

Fri 6/12

2:16 pm-6:56 pm

1 stop28h 40m

$335

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 8/18

11:00 am-5:45 pm

1 stop6h 45m

Des Moines

Wed 8/19

6:10 am-2:35 pm

2 stops8h 25m

$340

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 8/18

12:55 pm-9:00 pm

2 stops8h 05m

Des Moines

Wed 8/19

6:10 am-2:35 pm

2 stops8h 25m

$345

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 6/4

2:27 pm-10:32 pm

1 stop8h 05m

Des Moines

Sun 6/7

10:54 am-5:13 pm

1 stop6h 19m

$386
Quickest round-trip

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 6/17

9:17 am-4:03 pm

1 stop6h 46m

Des Moines

Sun 6/21

5:30 am-9:59 am

1 stop4h 29m

$395

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Fri 5/22

5:35 pm-11:57 pm

1 stop6h 22m

Des Moines

Wed 5/27

4:48 pm-11:59 pm

1 stop7h 11m

$396

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 6/9

6:10 am-3:05 pm

2 stops8h 55m

Des Moines

Fri 6/12

4:40 pm-1:00 am

2 stops8h 20m

$406

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Fri 7/31

7:40 am-1:34 pm

1 stop5h 54m

Des Moines

Mon 8/3

6:38 pm-12:24 am

1 stop5h 46m

$407

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Antonio to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Antonio and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in June, then September is your next best option. Flight prices from San Antonio to Des Moines during September average around $297.

How have San Antonio to Des Moines flight prices changed over time?

When to book flights from San Antonio to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Des Moines (SAT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Des Moines

Fastest flight time

4h 43m

Direct flights

None
The fastest flight from San Antonio to Des Moines takes 4h 43m
There are no direct flights from San Antonio to Des Moines. There are no popular flight routes from San Antonio to Des Moines.
Search flight deals

Frequently asked questions about flying from San Antonio to Des Moines

  • How far is San Antonio to Des Moines by plane?

    The distance between San Antonio and Des Moines is about 882.7 mi. By plane, this route typically takes 4h 43m.

  • When did momondo last update prices for flights from San Antonio Airport to Des Moines Airport?

    Prices for flights from San Antonio Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from San Antonio Airport to Des Moines Airport?

  • How old do you have to be to fly from San Antonio Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Des Moines?

Best airlines flying from San Antonio to Des Moines

Compare and see reviews for airlines that fly from San Antonio to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $263Free CancellationRating
7.4
9,682 reviews
Search United Airlines flights
American AirlinesPriceFrom $276Free CancellationRating
7.1
11,672 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Antonio to Des Moines for you.

Can I find flights from San Antonio to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from San Antonio with this policy.

How can momondo help me find flights from San Antonio to Des Moines?

Once all potential San Antonio to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Antonio to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Antonio to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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