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Cheap flights from San Antonio to Des Moines from $197

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Des Moines departing on 6/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Antonio to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:20 am - 10:43 am
SAT
-
DSM
5h 23m
1 stop
Delta Logo
6:55 am - 11:49 am
DSM
-
SAT
4h 54m
1 stop
$263Delta
Wed, Aug 5 - Tue, Aug 11
American Airlines Logo
6:52 pm - 12:25 am
SAT
-
DSM
5h 33m
1 stop
American Airlines Logo
4:13 pm - 10:50 pm
DSM
-
SAT
6h 37m
1 stop
$270American Airlines
Wed, Aug 5 - Tue, Aug 11
United Airlines Logo
6:30 am - 12:18 pm
SAT
-
DSM
5h 48m
1 stop
United Airlines Logo
9:13 am - 4:55 pm
DSM
-
SAT
7h 42m
1 stop
$290United Airlines
Thu, Aug 20 - Wed, Aug 26
United Airlines Logo
5:30 am - 10:52 am
SAT
-
DSM
5h 22m
1 stop
United Airlines Logo
3:20 pm - 10:39 pm
DSM
-
SAT
7h 19m
2 stops
$295United Airlines
Thu, Aug 20 - Wed, Aug 26
Southwest Logo
3:30 pm - 10:10 pm
SAT
-
DSM
6h 40m
2 stops
Southwest Logo
2:40 pm - 9:30 pm
DSM
-
SAT
6h 50m
2 stops
$302Southwest
Thu, Aug 20 - Wed, Aug 26
Delta Logo
6:30 am - 2:04 pm
SAT
-
DSM
7h 34m
1 stop
Delta Logo
2:54 pm - 9:04 pm
DSM
-
SAT
6h 10m
1 stop
$317Delta
Wed, Aug 5 - Tue, Aug 11
United Airlines Logo
6:35 am - 2:15 pm
SAT
-
DSM
7h 40m
1 stop
United Airlines Logo
6:00 am - 12:11 pm
DSM
-
SAT
6h 11m
1 stop
$343United Airlines
Tue, Oct 6 - Wed, Oct 7
Southwest Logo
1:30 pm - 9:55 pm
SAT
-
DSM
8h 25m
2 stops
Southwest Logo
2:40 pm - 10:55 pm
DSM
-
SAT
8h 15m
2 stops
$346Southwest
Wed, Aug 5 - Tue, Aug 11
United Airlines Logo
5:58 pm - 10:15 pm
SAT
-
DSM
4h 17m
1 stop
United Airlines Logo
1:24 pm - 10:51 pm
DSM
-
SAT
9h 27m
2 stops
$348United Airlines
Tue, Oct 6 - Wed, Oct 7
United Airlines Logo
4:17 pm - 11:59 pm
SAT
-
DSM
7h 42m
2 stops
United Airlines Logo
1:27 pm - 10:51 pm
DSM
-
SAT
9h 24m
2 stops
$353United Airlines
Tue, Oct 6 - Wed, Oct 7

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Delta flights from San Antonio to Des Moines

Our best Delta deals on San Antonio to Des Moines flight tickets
Delta
Aug 5
SAT5:20 amSan Antonio
5h 23m
1 stop
DSM10:43 amDes Moines
Aug 11
DSM6:55 amDes Moines
4h 54m
1 stop
SAT11:49 amSan Antonio
$263
Delta
Aug 5
SAT6:30 amSan Antonio
7h 34m
1 stop
DSM2:04 pmDes Moines
Aug 11
DSM2:54 pmDes Moines
6h 10m
1 stop
SAT9:04 pmSan Antonio
$317
Delta
Jul 21
SAT2:35 pmSan Antonio
7h 54m
1 stop
DSM10:29 pmDes Moines
Jul 22
DSM10:54 amDes Moines
6h 17m
1 stop
SAT5:11 pmSan Antonio
$355

American Airlines flights from San Antonio to Des Moines

Our best American Airlines deals on San Antonio to Des Moines flight tickets
American Airlines
Aug 5
SAT6:52 pmSan Antonio
5h 33m
1 stop
DSM12:25 amDes Moines
Aug 11
DSM4:13 pmDes Moines
6h 37m
1 stop
SAT10:50 pmSan Antonio
$270
American Airlines
Aug 6
SAT5:00 amSan Antonio
4h 01m
1 stop
DSM9:01 amDes Moines
Aug 10
DSM4:13 pmDes Moines
6h 37m
1 stop
SAT10:50 pmSan Antonio
$364
American Airlines
Aug 6
SAT12:29 pmSan Antonio
6h 12m
1 stop
DSM6:41 pmDes Moines
Aug 10
DSM4:13 pmDes Moines
6h 37m
1 stop
SAT10:50 pmSan Antonio
$370

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 8/5

5:20 am-10:43 am

1 stop5h 23m

Des Moines

Tue 8/11

6:55 am-11:49 am

1 stop4h 54m

$263

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 8/5

6:52 pm-12:25 am

1 stop5h 33m

Des Moines

Tue 8/11

4:13 pm-10:50 pm

1 stop6h 37m

$270

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 8/20

6:30 am-12:18 pm

1 stop5h 48m

Des Moines

Wed 8/26

9:13 am-4:55 pm

1 stop7h 42m

$290

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 8/20

5:30 am-10:52 am

1 stop5h 22m

Des Moines

Wed 8/26

3:20 pm-10:39 pm

2 stops7h 19m

$295

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 8/20

3:30 pm-10:10 pm

2 stops6h 40m

Des Moines

Wed 8/26

2:40 pm-9:30 pm

2 stops6h 50m

$302

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 8/5

6:30 am-2:04 pm

1 stop7h 34m

Des Moines

Tue 8/11

2:54 pm-9:04 pm

1 stop6h 10m

$317

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 10/6

6:35 am-2:15 pm

1 stop7h 40m

Des Moines

Wed 10/7

6:00 am-12:11 pm

1 stop6h 11m

$343

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 8/5

1:30 pm-9:55 pm

2 stops8h 25m

Des Moines

Tue 8/11

2:40 pm-10:55 pm

2 stops8h 15m

$346

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 10/6

5:58 pm-10:15 pm

1 stop4h 17m

Des Moines

Wed 10/7

1:24 pm-10:51 pm

2 stops9h 27m

$348

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 10/6

4:17 pm-11:59 pm

2 stops7h 42m

Des Moines

Wed 10/7

1:27 pm-10:51 pm

2 stops9h 24m

$353

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Antonio to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Antonio and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then January is your next best option. Flight prices from San Antonio to Des Moines during January average around $328.

How have San Antonio to Des Moines flight prices changed over time?

When to book flights from San Antonio to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Des Moines (SAT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Des Moines

Fastest flight time

4h 38m

Direct flights

None
The fastest flight from San Antonio to Des Moines takes 4h 38m
There are no direct flights from San Antonio to Des Moines. There are no popular flight routes from San Antonio to Des Moines.
Search flight deals

Frequently asked questions about flying from San Antonio to Des Moines

  • How far is San Antonio to Des Moines by plane?

    The distance between San Antonio and Des Moines is about 882.7 mi. By plane, this route typically takes 4h 38m.

  • When did momondo last update prices for flights from San Antonio Airport to Des Moines Airport?

    Prices for flights from San Antonio Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from San Antonio Airport to Des Moines Airport?

  • How old do you have to be to fly from San Antonio Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Des Moines?

Best airlines flying from San Antonio to Des Moines

Compare and see reviews for airlines that fly from San Antonio to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $263Free CancellationRating
7.4
9,818 reviews
Search United Airlines flights
American AirlinesPriceFrom $276Free CancellationRating
7.1
11,654 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Osceola
Urbandale
Johnston
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Antonio to Des Moines for you.

Can I find flights from San Antonio to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from San Antonio with this policy.

How can momondo help me find flights from San Antonio to Des Moines?

Once all potential San Antonio to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Antonio to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Antonio to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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