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Cheap flights from Tampa to Knoxville from $50

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Knoxville departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Tampa to Knoxville (PIE-TYS)

Cheap round-trip flights

Allegiant Air Logo
7:27 pm - 9:04 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
10:17 am - 12:00 pmTYS-PIE
1h 43mnonstop
$87Allegiant Air
Find Deal
Wed, Nov 12 - Sat, Nov 15
Allegiant Air Logo
4:15 pm - 5:52 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
9:17 pm - 10:58 pmTYS-PIE
1h 41mnonstop
$92Allegiant Air
Find Deal
Fri, Nov 7 - Mon, Nov 10
Allegiant Air Logo
6:27 pm - 8:05 pmPIE-TYS
1h 38mnonstop
Allegiant Air Logo
12:45 pm - 2:24 pmTYS-PIE
1h 39mnonstop
$102Allegiant Air
Find Deal
Sat, Sep 27 - Wed, Oct 1
Allegiant Air Logo
1:32 pm - 3:10 pmPIE-TYS
1h 38mnonstop
Allegiant Air Logo
4:22 pm - 6:03 pmTYS-PIE
1h 41mnonstop
$109Allegiant Air
Find Deal
Wed, Sep 24 - Sun, Sep 28
Allegiant Air Logo
7:27 pm - 9:04 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
9:28 pm - 11:09 pmTYS-PIE
1h 41mnonstop
$118Allegiant Air
Find Deal
Wed, Nov 12 - Fri, Nov 14
Allegiant Air Logo
6:59 pm - 8:36 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
9:54 pm - 11:33 pmTYS-PIE
1h 39mnonstop
$120Allegiant Air
Find Deal
Mon, Oct 6 - Fri, Oct 10
Allegiant Air Logo
7:22 pm - 8:59 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
3:25 pm - 5:06 pmTYS-PIE
1h 41mnonstop
$121Allegiant Air
Find Deal
Mon, Sep 22 - Mon, Sep 29
Allegiant Air Logo
6:05 pm - 7:42 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
1:20 pm - 3:01 pmTYS-PIE
1h 41mnonstop
$124Allegiant Air
Find Deal
Mon, Sep 15 - Thu, Sep 18
Allegiant Air Logo
10:31 am - 12:09 pmPIE-TYS
1h 38mnonstop
Allegiant Air Logo
8:00 am - 9:41 amTYS-PIE
1h 41mnonstop
$125Allegiant Air
Find Deal
Thu, Nov 20 - Sun, Nov 23
Allegiant Air Logo
7:27 pm - 9:04 pmPIE-TYS
1h 37mnonstop
Allegiant Air Logo
9:25 pm - 11:04 pmTYS-PIE
1h 39mnonstop
$131Allegiant Air
Find Deal
Fri, Oct 3 - Sun, Oct 5

Allegiant Air flights from Tampa to Knoxville

Our best Allegiant Air deals on Tampa to Knoxville flight tickets
Allegiant Air
Nov 12
PIE7:27 pmTampa St. Petersburg
1h 37m
TYS9:04 pmKnoxville McGhee Tyson
Nov 15
TYS10:17 amKnoxville McGhee Tyson
1h 43m
PIE12:00 pmTampa St. Petersburg
$87
Find similar
Allegiant Air
Nov 7
PIE4:15 pmTampa St. Petersburg
1h 37m
TYS5:52 pmKnoxville McGhee Tyson
Nov 10
TYS9:17 pmKnoxville McGhee Tyson
1h 41m
PIE10:58 pmTampa St. Petersburg
$92
Find similar
Allegiant Air
Sep 27
PIE6:27 pmTampa St. Petersburg
1h 38m
TYS8:05 pmKnoxville McGhee Tyson
Oct 1
TYS12:45 pmKnoxville McGhee Tyson
1h 39m
PIE2:24 pmTampa St. Petersburg
$102
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 31, 2025.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Wed 11/12

7:27 pm-9:04 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Sat 11/15

10:17 am-12:00 pm

Nonstop1h 43m

$87

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 11/7

4:15 pm-5:52 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Mon 11/10

9:17 pm-10:58 pm

Nonstop1h 41m

$92

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sat 9/27

6:27 pm-8:05 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 10/1

12:45 pm-2:24 pm

Nonstop1h 39m

$102

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Wed 9/24

1:32 pm-3:10 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Sun 9/28

4:22 pm-6:03 pm

Nonstop1h 41m

$109

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Wed 11/12

7:27 pm-9:04 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Fri 11/14

9:28 pm-11:09 pm

Nonstop1h 41m

$118

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 10/6

6:59 pm-8:36 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Fri 10/10

9:54 pm-11:33 pm

Nonstop1h 39m

$120

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 9/22

7:22 pm-8:59 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Mon 9/29

3:25 pm-5:06 pm

Nonstop1h 41m

$121

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 9/15

6:05 pm-7:42 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Thu 9/18

1:20 pm-3:01 pm

Nonstop1h 41m

$124

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Thu 11/20

10:31 am-12:09 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Sun 11/23

8:00 am-9:41 am

Nonstop1h 41m

$125

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 10/3

7:27 pm-9:04 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Sun 10/5

9:25 pm-11:04 pm

Nonstop1h 39m

$131

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Tampa to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Tampa, with most prices found around $99. If you aren’t able to travel during the month of March, then book flights to Knoxville from Tampa during February instead. Flights to Knoxville in February, while not as cheap as those in March, still average around $113.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Tampa to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $264. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Tampa to Knoxville for around $486.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Tampa to Knoxville when you can find flight prices for as low as $318. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $359.

What is the cheapest Tampa St. Petersburg to Knoxville McGhee Tyson flight route?

Fly from Tampa St. Petersburg to Knoxville McGhee Tyson for the best Tampa St. Petersburg - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $144 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Tampa for as low as $110 on momondo.

What cabin class options are available on Tampa St. Petersburg to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Tampa St. Petersburg to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Tampa to Knoxville flight prices changed over time?

As of August 2025, prices for Tampa to Knoxville flights are approximately 6% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Knoxville (PIE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Knoxville

Best Price Found

$57

Fastest flight time

1h 37m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Tampa in the past 72 hours is $57. The best round-trip flight deal from Tampa to Knoxville found on momondo in the last 72 hours is $114.
The fastest flight from Tampa to Knoxville takes 1h 37m
Direct flights go from Tampa to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Tampa St. Petersburg to Knoxville McGhee Tyson by plane?

    Tampa St. Petersburg and Knoxville McGhee Tyson are 559.5 mi apart from one another. Typically, this will take 1h 37m by plane in normal conditions.

  • When did momondo last update prices for flights from Tampa St. Petersburg Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Tampa St. Petersburg Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Tampa St. Petersburg Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Tampa St. Petersburg Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa St. Petersburg Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Tampa to Knoxville?

  • What is the most popular airline from Tampa to Knoxville?

Best airlines flying from Tampa to Knoxville

Compare and see reviews for airlines that fly from Tampa to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $85Free CancellationRating
7.2
703 reviews
Search Allegiant Air flights

  • Allegiant Air Flights From Tampa to Knoxville

    Allegiant Air flight deals from Tampa to Knoxville start from $85 round-trip. Over the 1 Allegiant Air flight for this route in a normal week, average airfare is usually $141 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Tampa to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Tampa to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Tampa with this policy.

How can momondo help me find flights from Tampa to Knoxville?

Once all potential Tampa to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Tampa to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

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