What is the cheapest airline that flies from Greater Rochester Intl to Knoxville McGhee Tyson?

United Airlines is the most popular carrier operating from Greater Rochester Intl to Knoxville McGhee Tyson

Which airport is the most popular layover for flights between Rochester and Knoxville?

Washington, D.C. (DCA) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Rochester according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Rochester to Knoxville?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 01m.

Which layover airport offers the lowest fares from Rochester to Knoxville?

Flights via Washington, D.C. (DCA) offer the lowest average round-trip price of $329.

Which layover airport has the shortest connection time from Rochester to Knoxville?

Charlotte (CLT) has the shortest average layover time for this route: 0h 48m.

When did momondo last update prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

There are 3 operators available for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport as of December 2025.

How old do you have to be to fly from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$238 Cheap Flights from Rochester to Knoxville in 2025/26

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2:48 pm - 7:27 pm

ROC

TYS

4h 39m1 stop

6:45 am - 1:43 pm

TYS

ROC

6h 58m1 stop

$280United Airlines

Wed, Feb 11 - Sun, Feb 15

2:48 pm - 7:27 pm

ROC

TYS

4h 39m1 stop

6:45 am - 2:14 pm

TYS

ROC

7h 29m2 stops

$285United Airlines

Wed, Feb 11 - Sun, Feb 15

6:11 pm - 11:45 pm

ROC

TYS

5h 34m1 stop

5:26 pm - 11:13 pm

TYS

ROC

5h 47m1 stop

$289Delta

Fri, Jan 30 - Mon, Feb 2

11:19 am - 6:46 pm

ROC

TYS

7h 27m2 stops

6:00 am - 10:47 am

TYS

ROC

4h 47m1 stop

$294American Airlines

Fri, Jan 30 - Mon, Feb 2

11:09 am - 6:46 pm

ROC

TYS

7h 37m2 stops

11:19 am - 5:45 pm

TYS

ROC

6h 26m2 stops

$299American Airlines

Fri, Jan 30 - Mon, Feb 2

10:37 am - 8:52 pm

ROC

TYS

10h 15m2 stops

6:45 am - 2:14 pm

TYS

ROC

7h 29m2 stops

$302United Airlines

Wed, Feb 11 - Sun, Feb 15

6:00 am - 11:12 am

ROC

TYS

5h 12m1 stop

5:26 pm - 11:13 pm

TYS

ROC

5h 47m1 stop

$337Delta

Tue, Feb 10 - Tue, Feb 10

1:26 pm - 8:52 pm

ROC

TYS

7h 26m1 stop

2:25 pm - 7:06 pm

TYS

ROC

4h 41m1 stop

$341United Airlines

Sat, Jan 31 - Wed, Feb 4

5:20 am - 10:49 am

ROC

TYS

5h 29m1 stop

4:00 pm - 11:51 pm

TYS

ROC

7h 51m2 stops

$342American Airlines

Tue, Feb 10 - Tue, Feb 10

6:15 am - 1:24 pm

ROC

TYS

7h 09m1 stop

11:10 am - 10:59 pm

TYS

ROC

11h 49m2 stops

$346United Airlines

Sat, Jan 31 - Wed, Feb 4

Delta flights from Rochester to Knoxville

Our best Delta deals on Rochester to Knoxville flight tickets

Delta

Jan 30

ROC6:11 pmGreater Rochester Intl

5h 34m

1 stop

TYS11:45 pmKnoxville McGhee Tyson

Feb 2

TYS5:26 pmKnoxville McGhee Tyson

5h 47m

1 stop

ROC11:13 pmGreater Rochester Intl

$289

Find similar

Delta

Feb 10

ROC6:00 amGreater Rochester Intl

5h 12m

1 stop

TYS11:12 amKnoxville McGhee Tyson

Feb 10

TYS5:26 pmKnoxville McGhee Tyson

5h 47m

1 stop

ROC11:13 pmGreater Rochester Intl

$337

Find similar

American Airlines flights from Rochester to Knoxville

Our best American Airlines deals on Rochester to Knoxville flight tickets

American Airlines

Jan 30

ROC11:19 amGreater Rochester Intl

7h 27m

2 stops

TYS6:46 pmKnoxville McGhee Tyson

Feb 2

TYS6:00 amKnoxville McGhee Tyson

4h 47m

1 stop

ROC10:47 amGreater Rochester Intl

$294

Find similar

American Airlines

Jan 30

ROC11:09 amGreater Rochester Intl

7h 37m

2 stops

TYS6:46 pmKnoxville McGhee Tyson

Feb 2

TYS11:19 amKnoxville McGhee Tyson

6h 26m

2 stops

ROC5:45 pmGreater Rochester Intl

$299

Find similar

American Airlines

Feb 10

ROC5:20 amGreater Rochester Intl

5h 29m

1 stop

TYS10:49 amKnoxville McGhee Tyson

Feb 10

TYS4:00 pmKnoxville McGhee Tyson

7h 51m

2 stops

ROC11:51 pmGreater Rochester Intl

$342

Find similar

Fly from

Fly to

Route

Depart

Return

Price

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 2/11

2:48 pm-7:27 pm

1 stop4h 39m

Knoxville McGhee Tyson

Sun 2/15

6:45 am-1:43 pm

1 stop6h 58m

$280

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 2/11

2:48 pm-7:27 pm

1 stop4h 39m

Knoxville McGhee Tyson

Sun 2/15

6:45 am-2:14 pm

2 stops7h 29m

$285

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Fri 1/30

6:11 pm-11:45 pm

1 stop5h 34m

Knoxville McGhee Tyson

Mon 2/2

5:26 pm-11:13 pm

1 stop5h 47m

$289

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Fri 1/30

11:19 am-6:46 pm

2 stops7h 27m

Knoxville McGhee Tyson

Mon 2/2

6:00 am-10:47 am

1 stop4h 47m

$294

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Fri 1/30

11:09 am-6:46 pm

2 stops7h 37m

Knoxville McGhee Tyson

Mon 2/2

11:19 am-5:45 pm

2 stops6h 26m

$299

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 2/11

10:37 am-8:52 pm

2 stops10h 15m

Knoxville McGhee Tyson

Sun 2/15

6:45 am-2:14 pm

2 stops7h 29m

$302

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 2/10

6:00 am-11:12 am

1 stop5h 12m

Knoxville McGhee Tyson

Tue 2/10

5:26 pm-11:13 pm

1 stop5h 47m

$337

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 1/31

1:26 pm-8:52 pm

1 stop7h 26m

Knoxville McGhee Tyson

Wed 2/4

2:25 pm-7:06 pm

1 stop4h 41m

$341

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 2/10

5:20 am-10:49 am

1 stop5h 29m

Knoxville McGhee Tyson

Tue 2/10

4:00 pm-11:51 pm

2 stops7h 51m

$342

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 1/31

6:15 am-1:24 pm

1 stop7h 09m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-10:59 pm

2 stops11h 49m

$346

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How to get the cheapest flight ticket from Rochester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Rochester, with most prices found around $281. If you aren’t able to travel during the month of February, then book flights to Knoxville from Rochester during September instead. Flights to Knoxville in September, while not as cheap as those in February, still average around $293.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Rochester to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $318. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Rochester to Knoxville for around $383.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Rochester to Knoxville when you can find flight prices for as low as $317. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $359.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Rochester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $360 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Rochester for as low as $261 on momondo.

When to book flights from Rochester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Rochester to Knoxville (ROC to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Knoxville

Fastest flight time	4h 14m
Direct flights	None

The fastest flight from Rochester to Knoxville takes 4h 14m

There are no direct flights from Rochester to Knoxville. There are no popular flight routes from Rochester to Knoxville.

Search flight deals

How far is Greater Rochester Intl to Knoxville McGhee Tyson by plane?
Knoxville McGhee Tyson is 599.1 mi away from Greater Rochester Intl. 4h 14m is a normal flight duration for this route.
When did momondo last update prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?
There are 3 operators available for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport as of December 2025.
How old do you have to be to fly from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Rochester to Knoxville?
Based on momondo bookings for flights between Rochester and Knoxville, the leading airline is American Airlines, making up 63% of the total bookings. Other popular airlines include Delta with 24% and United Airlines with 13%.

Best airlines flying from Rochester to Knoxville

Compare and see reviews for airlines that fly from Rochester to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $239	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,095 reviews	Search United Airlines flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,050 reviews	Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Maryville

Crossville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Knoxville?

It is quick and easy to find Rochester to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Rochester to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Rochester to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Rochester to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Rochester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Rochester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Rochester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Cheap flights from Rochester to Knoxville from $280

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Knoxville departing on 2/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Rochester to Knoxville

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How to get the cheapest flight ticket from Rochester to Knoxville

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

How far in advance should I book a flight to Knoxville?

What is the cheapest airline that flies from Greater Rochester Intl to Knoxville McGhee Tyson?

United Airlines is the most popular carrier operating from Greater Rochester Intl to Knoxville McGhee Tyson

What airlines fly to Knoxville?

Which airport is the most popular layover for flights between Rochester and Knoxville?

Washington, D.C. (DCA) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Rochester to Knoxville?

Flights via Washington, D.C. (DCA) offer the lowest average round-trip price of $329.

Which layover airport has the shortest travel time from Rochester to Knoxville?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 01m.

Which layover airport has the shortest connection time from Rochester to Knoxville?

Charlotte (CLT) has the shortest average layover time for this route: 0h 48m.

When to book flights from Rochester to Knoxville

Cheap Rochester to Knoxville (ROC to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Knoxville

Fastest flight time

Direct flights

How far is Greater Rochester Intl to Knoxville McGhee Tyson by plane?

When did momondo last update prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

What is the most popular airline from Rochester to Knoxville?

Best airlines flying from Rochester to Knoxville

Compare and see reviews for airlines that fly from Rochester to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Knoxville?

Can I find flights from Rochester to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Rochester to Knoxville?

I’m not ready to book a flight from Rochester to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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Airports servicing Tennessee