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Cheap flights from Rochester to Knoxville from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Knoxville departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Rochester to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
10:13 am - 10:05 pm
ROC
-
TYS
11h 52m
1 stop
Allegiant Air Logo
4:25 pm - 9:23 am
TYS
-
ROC
16h 58m
1 stop
$238Allegiant Air
Thu, Apr 9 - Wed, Apr 15
American Airlines Logo
5:46 pm - 9:40 pm
ROC
-
TYS
3h 54m
1 stop
American Airlines Logo
4:15 pm - 9:50 pm
TYS
-
ROC
5h 35m
1 stop
$303American Airlines
Tue, Apr 28 - Sat, May 2
American Airlines Logo
5:46 pm - 9:40 pm
ROC
-
TYS
3h 54m
1 stop
American Airlines Logo
8:00 am - 1:00 pm
TYS
-
ROC
5h 00m
1 stop
$311American Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
10:32 am - 3:09 pm
ROC
-
TYS
4h 37m
1 stop
United Airlines Logo
7:00 am - 2:15 pm
TYS
-
ROC
7h 15m
2 stops
$316United Airlines
Tue, Apr 28 - Sat, May 2
American Airlines Logo
5:15 am - 11:01 am
ROC
-
TYS
5h 46m
1 stop
American Airlines Logo
4:15 pm - 9:50 pm
TYS
-
ROC
5h 35m
1 stop
$325American Airlines
Sun, Apr 26 - Sat, May 2
Southwest Logo
6:35 am - 5:10 pm
ROC
-
TYS
10h 35m
2 stops
Southwest Logo
6:40 am - 4:20 pm
TYS
-
ROC
9h 40m
2 stops
$327Southwest
Tue, Apr 28 - Sat, May 2
Southwest Logo
11:55 am - 7:50 pm
ROC
-
TYS
7h 55m
1 stop
Southwest Logo
8:00 am - 12:15 pm
TYS
-
ROC
4h 15m
1 stop
$330Southwest
Wed, Aug 12 - Tue, Aug 18
Multiple Airlines Logo
10:13 am - 5:30 pm
ROC
-
TYS
31h 17m
2 stops
Multiple Airlines Logo
4:25 pm - 9:23 am
TYS
-
ROC
16h 58m
1 stop
$331Multiple Airlines
Thu, Apr 9 - Wed, Apr 15
Southwest Logo
11:55 am - 6:55 pm
ROC
-
TYS
7h 00m
2 stops
Southwest Logo
7:00 am - 2:40 pm
TYS
-
ROC
7h 40m
2 stops
$335Southwest
Wed, Aug 12 - Tue, Aug 18
Delta Logo
5:48 pm - 9:20 pm
ROC
-
TYS
3h 32m
1 stop
Delta Logo
5:40 am - 11:53 am
TYS
-
ROC
6h 13m
1 stop
$336Delta
Wed, Apr 15 - Sun, Apr 19

Allegiant Air flights from Rochester to Knoxville

Our best Allegiant Air deals on Rochester to Knoxville flight tickets
Allegiant Air
Apr 9
ROC10:13 amGreater Rochester Intl
11h 52m
1 stop
TYS10:05 pmKnoxville McGhee Tyson
Apr 15
TYS4:25 pmKnoxville McGhee Tyson
16h 58m
1 stop
ROC9:23 amGreater Rochester Intl
$238
Allegiant Air
Apr 11
ROC6:12 pmGreater Rochester Intl
26h 15m
1 stop
TYS8:27 pmKnoxville McGhee Tyson
Apr 15
TYS4:25 pmKnoxville McGhee Tyson
16h 58m
1 stop
ROC9:23 amGreater Rochester Intl
$347
Allegiant Air
Apr 9
ROC10:13 amGreater Rochester Intl
11h 52m
1 stop
TYS10:05 pmKnoxville McGhee Tyson
Apr 14
TYS10:30 amKnoxville McGhee Tyson
25h 52m
1 stop
ROC12:22 pmGreater Rochester Intl
$404

American Airlines flights from Rochester to Knoxville

Our best American Airlines deals on Rochester to Knoxville flight tickets
American Airlines
Apr 28
ROC5:46 pmGreater Rochester Intl
3h 54m
1 stop
TYS9:40 pmKnoxville McGhee Tyson
May 2
TYS4:15 pmKnoxville McGhee Tyson
5h 35m
1 stop
ROC9:50 pmGreater Rochester Intl
$303
American Airlines
Apr 28
ROC5:46 pmGreater Rochester Intl
3h 54m
1 stop
TYS9:40 pmKnoxville McGhee Tyson
May 2
TYS8:00 amKnoxville McGhee Tyson
5h 00m
1 stop
ROC1:00 pmGreater Rochester Intl
$311
American Airlines
Apr 26
ROC5:15 amGreater Rochester Intl
5h 46m
1 stop
TYS11:01 amKnoxville McGhee Tyson
May 2
TYS4:15 pmKnoxville McGhee Tyson
5h 35m
1 stop
ROC9:50 pmGreater Rochester Intl
$325

momondo Fare Finder

 
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Thu 4/9

10:13 am-10:05 pm

1 stop11h 52m

Knoxville McGhee Tyson

Wed 4/15

4:25 pm-9:23 am

1 stop16h 58m

$238

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 4/28

5:46 pm-9:40 pm

1 stop3h 54m

Knoxville McGhee Tyson

Sat 5/2

4:15 pm-9:50 pm

1 stop5h 35m

$303
Quickest round-trip

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 4/28

5:46 pm-9:40 pm

1 stop3h 54m

Knoxville McGhee Tyson

Sat 5/2

8:00 am-1:00 pm

1 stop5h 00m

$311

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 4/28

10:32 am-3:09 pm

1 stop4h 37m

Knoxville McGhee Tyson

Sat 5/2

7:00 am-2:15 pm

2 stops7h 15m

$316

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sun 4/26

5:15 am-11:01 am

1 stop5h 46m

Knoxville McGhee Tyson

Sat 5/2

4:15 pm-9:50 pm

1 stop5h 35m

$325

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 4/28

6:35 am-5:10 pm

2 stops10h 35m

Knoxville McGhee Tyson

Sat 5/2

6:40 am-4:20 pm

2 stops9h 40m

$327

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 8/12

11:55 am-7:50 pm

1 stop7h 55m

Knoxville McGhee Tyson

Tue 8/18

8:00 am-12:15 pm

1 stop4h 15m

$330

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Thu 4/9

10:13 am-5:30 pm

2 stops31h 17m

Knoxville McGhee Tyson

Wed 4/15

4:25 pm-9:23 am

1 stop16h 58m

$331

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 8/12

11:55 am-6:55 pm

2 stops7h 00m

Knoxville McGhee Tyson

Tue 8/18

7:00 am-2:40 pm

2 stops7h 40m

$335

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 4/15

5:48 pm-9:20 pm

1 stop3h 32m

Knoxville McGhee Tyson

Sun 4/19

5:40 am-11:53 am

1 stop6h 13m

$336

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Rochester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of September is, on average, the cheapest month to fly to Knoxville from Rochester, with most prices found around $293. If you aren’t able to travel during the month of September, then book flights to Knoxville from Rochester during April instead. Flights to Knoxville in April, while not as cheap as those in September, still average around $323.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Rochester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $356 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Rochester for as low as $259 on momondo.

When to book flights from Rochester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rochester to Knoxville (ROC to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Knoxville

Fastest flight time

4h 36m

Direct flights

None
The fastest flight from Rochester to Knoxville takes 4h 36m
There are no direct flights from Rochester to Knoxville. There are no popular flight routes from Rochester to Knoxville.
Search flight deals

  • How far is Greater Rochester Intl to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 599.1 mi away from Greater Rochester Intl. 4h 36m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greater Rochester Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Rochester to Knoxville?

Best airlines flying from Rochester to Knoxville

Compare and see reviews for airlines that fly from Rochester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $168Free CancellationRating
7.9
8,319 reviews
Search Delta flights
United AirlinesPriceFrom $179Free CancellationRating
7.4
9,460 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Knoxville?

It is quick and easy to find Rochester to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Rochester to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Rochester to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Rochester to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Rochester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Rochester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Rochester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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