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Cheap flights from Rochester to Des Moines from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Des Moines departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Rochester to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:43 pm - 9:53 pm
ROC
-
DSM
5h 10m
1 stop
American Airlines Logo
5:01 pm - 11:38 pm
DSM
-
ROC
5h 37m
1 stop
$349American Airlines
Thu, May 7 - Tue, May 12
American Airlines Logo
7:44 pm - 11:49 pm
ROC
-
DSM
5h 05m
1 stop
American Airlines Logo
8:56 am - 6:35 pm
DSM
-
ROC
8h 39m
2 stops
$354American Airlines
Thu, May 7 - Tue, May 12
United Airlines Logo
5:46 pm - 11:24 pm
ROC
-
DSM
6h 38m
1 stop
United Airlines Logo
10:02 am - 4:45 pm
DSM
-
ROC
5h 43m
1 stop
$360United Airlines
Thu, May 7 - Tue, May 12
Southwest Logo
7:50 pm - 11:05 pm
ROC
-
DSM
4h 15m
1 stop
Southwest Logo
6:55 am - 3:20 pm
DSM
-
ROC
7h 25m
2 stops
$365Southwest
Thu, May 7 - Tue, May 12
American Airlines Logo
6:46 pm - 12:17 am
ROC
-
DSM
6h 31m
1 stop
American Airlines Logo
5:00 am - 10:55 am
DSM
-
ROC
4h 55m
1 stop
$371American Airlines
Wed, May 27 - Sat, May 30
American Airlines Logo
12:00 pm - 7:32 pm
ROC
-
DSM
8h 32m
2 stops
American Airlines Logo
5:00 am - 10:55 am
DSM
-
ROC
4h 55m
1 stop
$376American Airlines
Wed, May 27 - Sat, May 30
Southwest Logo
12:35 pm - 9:55 pm
ROC
-
DSM
10h 20m
2 stops
Southwest Logo
6:55 am - 3:20 pm
DSM
-
ROC
7h 25m
2 stops
$389Southwest
Thu, May 7 - Tue, May 12
American Airlines Logo
6:46 pm - 12:17 am
ROC
-
DSM
6h 31m
1 stop
American Airlines Logo
1:37 pm - 10:27 pm
DSM
-
ROC
7h 50m
1 stop
$407American Airlines
Thu, May 21 - Mon, May 25
Delta Logo
6:00 am - 11:08 am
ROC
-
DSM
6h 08m
1 stop
Delta Logo
5:56 pm - 10:50 pm
DSM
-
ROC
3h 54m
1 stop
$408Delta
Wed, May 20 - Sun, May 24
United Airlines Logo
5:35 pm - 9:32 pm
ROC
-
DSM
4h 57m
1 stop
United Airlines Logo
8:04 am - 1:39 pm
DSM
-
ROC
4h 35m
1 stop
$426United Airlines
Sat, Apr 25 - Wed, Apr 29

United Airlines flights from Rochester to Des Moines

Our best United Airlines deals on Rochester to Des Moines flight tickets
United Airlines
May 7
ROC5:46 pmGreater Rochester Intl
6h 38m
1 stop
DSM11:24 pmDes Moines
May 12
DSM10:02 amDes Moines
5h 43m
1 stop
ROC4:45 pmGreater Rochester Intl
$360
United Airlines
Apr 25
ROC5:35 pmGreater Rochester Intl
4h 57m
1 stop
DSM9:32 pmDes Moines
Apr 29
DSM8:04 amDes Moines
4h 35m
1 stop
ROC1:39 pmGreater Rochester Intl
$426
United Airlines
Apr 25
ROC2:25 pmGreater Rochester Intl
10h 17m
2 stops
DSM11:42 pmDes Moines
Apr 29
DSM8:04 amDes Moines
4h 35m
1 stop
ROC1:39 pmGreater Rochester Intl
$431

Southwest flights from Rochester to Des Moines

Our best Southwest deals on Rochester to Des Moines flight tickets
Southwest
May 7
ROC7:50 pmGreater Rochester Intl
4h 15m
1 stop
DSM11:05 pmDes Moines
May 12
DSM6:55 amDes Moines
7h 25m
2 stops
ROC3:20 pmGreater Rochester Intl
$365
Southwest
May 7
ROC12:35 pmGreater Rochester Intl
10h 20m
2 stops
DSM9:55 pmDes Moines
May 12
DSM6:55 amDes Moines
7h 25m
2 stops
ROC3:20 pmGreater Rochester Intl
$389
Southwest
Apr 15
ROC8:05 amGreater Rochester Intl
4h 20m
1 stop
DSM11:25 amDes Moines
Apr 19
DSM4:20 pmDes Moines
6h 45m
2 stops
ROC12:05 amGreater Rochester Intl
$492

momondo Fare Finder

 
Customize your flight search to find flights from Rochester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Rochester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/7

5:43 pm-9:53 pm

1 stop5h 10m

Des Moines

Tue 5/12

5:01 pm-11:38 pm

1 stop5h 37m

$349

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/7

7:44 pm-11:49 pm

1 stop5h 05m

Des Moines

Tue 5/12

8:56 am-6:35 pm

2 stops8h 39m

$354

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/7

5:46 pm-11:24 pm

1 stop6h 38m

Des Moines

Tue 5/12

10:02 am-4:45 pm

1 stop5h 43m

$360

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/7

7:50 pm-11:05 pm

1 stop4h 15m

Des Moines

Tue 5/12

6:55 am-3:20 pm

2 stops7h 25m

$365

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 5/27

6:46 pm-12:17 am

1 stop6h 31m

Des Moines

Sat 5/30

5:00 am-10:55 am

1 stop4h 55m

$371

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 5/27

12:00 pm-7:32 pm

2 stops8h 32m

Des Moines

Sat 5/30

5:00 am-10:55 am

1 stop4h 55m

$376

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/7

12:35 pm-9:55 pm

2 stops10h 20m

Des Moines

Tue 5/12

6:55 am-3:20 pm

2 stops7h 25m

$389

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 5/21

6:46 pm-12:17 am

1 stop6h 31m

Des Moines

Mon 5/25

1:37 pm-10:27 pm

1 stop7h 50m

$407

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 5/20

6:00 am-11:08 am

1 stop6h 08m

Des Moines

Sun 5/24

5:56 pm-10:50 pm

1 stop3h 54m

$408
Quickest round-trip

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Sat 4/25

5:35 pm-9:32 pm

1 stop4h 57m

Des Moines

Wed 4/29

8:04 am-1:39 pm

1 stop4h 35m

$426

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Rochester to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Rochester and Des Moines?

When to book flights from Rochester to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rochester to Des Moines (ROC to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Des Moines

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Rochester to Des Moines takes 4h 53m
There are no direct flights from Rochester to Des Moines. There are no popular flight routes from Rochester to Des Moines.
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Frequently asked questions about flying from Rochester to Des Moines

  • How far is Greater Rochester Intl to Des Moines by plane?

    Greater Rochester Intl and Des Moines are 822.7 mi apart from one another. A reasonable flight in good conditions will take 4h 53m.

  • When did momondo last update prices for flights from Greater Rochester Intl Airport to Des Moines Airport?

    Prices for flights from Greater Rochester Intl Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Greater Rochester Intl Airport to Des Moines Airport?

  • How old do you have to be to fly from Greater Rochester Intl Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greater Rochester Intl Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Rochester to Des Moines?

Best airlines flying from Rochester to Des Moines

Compare and see reviews for airlines that fly from Rochester to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,383 reviews
Search Delta flights
United AirlinesPriceFrom $237Free CancellationRating
7.4
9,541 reviews
Search United Airlines flights
American AirlinesPriceFrom $321Free CancellationRating
7.1
11,555 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Des Moines?

Finding the right flight to Des Moines from Rochester is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Rochester to Des Moines with flexible booking policies on momondo?

All flight searches from Rochester to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Rochester to Des Moines?

Once you have performed a search for Rochester to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Rochester to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Rochester and alert you when they change.

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