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Cheap flights from Rochester to Des Moines from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Des Moines departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Rochester to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:52 pm - 10:51 pm
ROC
-
DSM
5h 59m
1 stop
United Airlines Logo
11:23 am - 4:45 pm
DSM
-
ROC
4h 22m
1 stop
$355United Airlines
Wed, Jul 1 - Wed, Jul 8
American Airlines Logo
6:46 pm - 12:07 am
ROC
-
DSM
6h 21m
1 stop
American Airlines Logo
1:41 pm - 11:06 pm
DSM
-
ROC
8h 25m
2 stops
$360American Airlines
Wed, Jul 1 - Wed, Jul 8
American Airlines Logo
5:50 am - 1:03 pm
ROC
-
DSM
8h 13m
2 stops
American Airlines Logo
1:41 pm - 11:06 pm
DSM
-
ROC
8h 25m
2 stops
$366American Airlines
Wed, Jul 1 - Wed, Jul 8
Southwest Logo
7:05 pm - 10:45 pm
ROC
-
DSM
4h 40m
1 stop
Southwest Logo
4:15 pm - 10:25 pm
DSM
-
ROC
5h 10m
1 stop
$381Southwest
Wed, Jul 1 - Sun, Jul 5
Southwest Logo
4:25 pm - 10:45 pm
ROC
-
DSM
7h 20m
2 stops
Southwest Logo
4:15 pm - 10:25 pm
DSM
-
ROC
5h 10m
1 stop
$386Southwest
Wed, Jul 1 - Sun, Jul 5
Southwest Logo
7:35 pm - 11:30 pm
ROC
-
DSM
4h 55m
1 stop
Southwest Logo
5:40 am - 10:55 am
DSM
-
ROC
4h 15m
1 stop
$396Southwest
Thu, Jul 30 - Mon, Aug 10
Southwest Logo
12:55 pm - 11:30 pm
ROC
-
DSM
11h 35m
2 stops
Southwest Logo
6:10 am - 5:30 pm
DSM
-
ROC
10h 20m
2 stops
$397Southwest
Thu, Jul 30 - Tue, Aug 11
Southwest Logo
6:20 am - 1:45 pm
ROC
-
DSM
8h 25m
2 stops
Southwest Logo
5:40 am - 10:55 am
DSM
-
ROC
4h 15m
1 stop
$401Southwest
Fri, Aug 28 - Mon, Aug 31
American Airlines Logo
7:03 pm - 12:06 am
ROC
-
DSM
6h 03m
1 stop
American Airlines Logo
5:00 am - 11:00 am
DSM
-
ROC
5h 00m
1 stop
$406American Airlines
Thu, Jul 2 - Thu, Jul 9
American Airlines Logo
5:00 am - 8:23 am
ROC
-
DSM
4h 23m
1 stop
American Airlines Logo
1:41 pm - 10:27 pm
DSM
-
ROC
7h 46m
1 stop
$407American Airlines
Sun, Jul 12 - Fri, Jul 17

United Airlines flights from Rochester to Des Moines

Our best United Airlines deals on Rochester to Des Moines flight tickets
United Airlines
Jul 1
ROC5:52 pmGreater Rochester Intl
5h 59m
1 stop
DSM10:51 pmDes Moines
Jul 8
DSM11:23 amDes Moines
4h 22m
1 stop
ROC4:45 pmGreater Rochester Intl
$355
United Airlines
Oct 27
ROC6:20 amGreater Rochester Intl
5h 00m
1 stop
DSM10:20 amDes Moines
Oct 31
DSM5:00 amDes Moines
7h 28m
1 stop
ROC1:28 pmGreater Rochester Intl
$441
United Airlines
Oct 27
ROC4:00 pmGreater Rochester Intl
9h 40m
2 stops
DSM12:40 amDes Moines
Oct 31
DSM3:15 pmDes Moines
4h 53m
1 stop
ROC9:08 pmGreater Rochester Intl
$446

American Airlines flights from Rochester to Des Moines

Our best American Airlines deals on Rochester to Des Moines flight tickets
American Airlines
Jul 1
ROC6:46 pmGreater Rochester Intl
6h 21m
1 stop
DSM12:07 amDes Moines
Jul 8
DSM1:41 pmDes Moines
8h 25m
2 stops
ROC11:06 pmGreater Rochester Intl
$360
American Airlines
Jul 1
ROC5:50 amGreater Rochester Intl
8h 13m
2 stops
DSM1:03 pmDes Moines
Jul 8
DSM1:41 pmDes Moines
8h 25m
2 stops
ROC11:06 pmGreater Rochester Intl
$366
American Airlines
Jul 2
ROC7:03 pmGreater Rochester Intl
6h 03m
1 stop
DSM12:06 amDes Moines
Jul 9
DSM5:00 amDes Moines
5h 00m
1 stop
ROC11:00 amGreater Rochester Intl
$406

momondo Fare Finder

 
Customize your flight search to find flights from Rochester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Rochester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 7/1

5:52 pm-10:51 pm

1 stop5h 59m

Des Moines

Wed 7/8

11:23 am-4:45 pm

1 stop4h 22m

$355

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 7/1

6:46 pm-12:07 am

1 stop6h 21m

Des Moines

Wed 7/8

1:41 pm-11:06 pm

2 stops8h 25m

$360

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 7/1

5:50 am-1:03 pm

2 stops8h 13m

Des Moines

Wed 7/8

1:41 pm-11:06 pm

2 stops8h 25m

$366

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 7/1

7:05 pm-10:45 pm

1 stop4h 40m

Des Moines

Sun 7/5

4:15 pm-10:25 pm

1 stop5h 10m

$381

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Wed 7/1

4:25 pm-10:45 pm

2 stops7h 20m

Des Moines

Sun 7/5

4:15 pm-10:25 pm

1 stop5h 10m

$386
Quickest round-trip

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 7/30

7:35 pm-11:30 pm

1 stop4h 55m

Des Moines

Mon 8/10

5:40 am-10:55 am

1 stop4h 15m

$396

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 7/30

12:55 pm-11:30 pm

2 stops11h 35m

Des Moines

Tue 8/11

6:10 am-5:30 pm

2 stops10h 20m

$397

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Fri 8/28

6:20 am-1:45 pm

2 stops8h 25m

Des Moines

Mon 8/31

5:40 am-10:55 am

1 stop4h 15m

$401

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Thu 7/2

7:03 pm-12:06 am

1 stop6h 03m

Des Moines

Thu 7/9

5:00 am-11:00 am

1 stop5h 00m

$406

RochesterDes Moines

ROC - DSM

ROCDSM

Greater Rochester Intl

Sun 7/12

5:00 am-8:23 am

1 stop4h 23m

Des Moines

Fri 7/17

1:41 pm-10:27 pm

1 stop7h 46m

$407

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Rochester to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Rochester and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in January, then October is your next best option. Flight prices from Rochester to Des Moines during October average around $321.

When to book flights from Rochester to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rochester to Des Moines (ROC to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Des Moines

Fastest flight time

3h 53m

Direct flights

None
The fastest flight from Rochester to Des Moines takes 3h 53m
There are no direct flights from Rochester to Des Moines. There are no popular flight routes from Rochester to Des Moines.
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Frequently asked questions about flying from Rochester to Des Moines

  • How far is Greater Rochester Intl to Des Moines by plane?

    Greater Rochester Intl and Des Moines are 822.7 mi apart from one another. A reasonable flight in good conditions will take 3h 53m.

  • When did momondo last update prices for flights from Greater Rochester Intl Airport to Des Moines Airport?

    Prices for flights from Greater Rochester Intl Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Greater Rochester Intl Airport to Des Moines Airport?

  • How old do you have to be to fly from Greater Rochester Intl Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greater Rochester Intl Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Rochester to Des Moines?

Best airlines flying from Rochester to Des Moines

Compare and see reviews for airlines that fly from Rochester to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $237Free CancellationRating
7.4
9,751 reviews
Search United Airlines flights
DeltaPriceFrom $253Free CancellationRating
7.9
8,449 reviews
Search Delta flights
American AirlinesPriceFrom $321Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights
SouthwestPriceFrom $357Free CancellationRating
7.9
4,277 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Des Moines?

Finding the right flight to Des Moines from Rochester is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Rochester to Des Moines with flexible booking policies on momondo?

All flight searches from Rochester to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Rochester to Des Moines?

Once you have performed a search for Rochester to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Rochester to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Rochester and alert you when they change.

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