What airlines fly to South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to South Carolina from Rochester, Minnesota according to our data. Delta is the first choice among our users, with 41% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Rochester to South Carolina?

American Airlines and Delta are the most popular carriers operating from Rochester to South Carolina

When did momondo last update prices for flights from Rochester Airport to South Carolina?

Prices for flights from Rochester Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Rochester Airport to South Carolina?

The number of operators available for flights from Rochester Airport to South Carolina is 1 as of October 2026.

How old do you have to be to fly from Rochester Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Rochester Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$258 Cheap Flights from Rochester, Minnesota to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Rochester, Minnesota to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:02 am - 3:24 pmRST Rochester-CHS Charleston

7h 22m1 stop Chicago O'Hare Intl

7:13 am - 12:03 pmCHS Charleston-RST Rochester

5h 50m1 stop Chicago O'Hare Intl

$338American Airlines

Fri, Nov 13 - Tue, Nov 17

7:02 am - 3:24 pmRST Rochester-CHS Charleston

7h 22m1 stop Chicago O'Hare Intl

4:13 pm - 11:59 pmCHS Charleston-RST Rochester

8h 46m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$344American Airlines

Fri, Nov 13 - Tue, Nov 17

12:34 pm - 10:37 pmRST Rochester-CHS Charleston

9h 03m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

2:40 pm - 11:59 pmCHS Charleston-RST Rochester

10h 19m2 stops Charlotte Douglas Chicago O'Hare Intl

$419American Airlines

Fri, Nov 13 - Tue, Nov 17

12:34 pm - 10:58 pmRST Rochester-MYR Myrtle Beach Intl

9h 24m2 stops Chicago O'Hare Intl Charlotte Douglas

6:00 am - 3:45 pmMYR Myrtle Beach Intl-RST Rochester

10h 45m2 stops Charlotte Douglas Chicago O'Hare Intl

$449American Airlines

Sat, Feb 6 - Sat, Feb 13

12:38 pm - 5:57 pmRST Rochester-GSP Greenville

4h 19m1 stop Chicago O'Hare Intl

6:27 pm - 12:06 amGSP Greenville-RST Rochester

6h 39m1 stop Chicago O'Hare Intl

$478American Airlines

Thu, Nov 19 - Sun, Nov 22

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

6:43 pm - 12:07 amGSP Greenville-RST Rochester

6h 24m1 stop Chicago O'Hare Intl

$484American Airlines

Sat, Oct 17 - Sat, Oct 24

12:38 pm - 5:57 pmRST Rochester-GSP Greenville

4h 19m1 stop Chicago O'Hare Intl

3:58 pm - 12:06 amGSP Greenville-RST Rochester

9h 08m2 stops Charlotte Douglas Chicago O'Hare Intl

$484American Airlines

Thu, Nov 19 - Sun, Nov 22

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

7:17 am - 3:46 pmGSP Greenville-RST Rochester

9h 29m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$490American Airlines

Sat, Oct 17 - Sat, Oct 24

12:40 pm - 10:12 pmRST Rochester-GSP Greenville

8h 32m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

10:56 am - 10:13 amGSP Greenville-RST Rochester

24h 17m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul

$858Delta

Thu, Nov 26 - Sun, Nov 29

12:40 pm - 10:12 pmRST Rochester-GSP Greenville

8h 32m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

8:11 am - 3:35 pmGSP Greenville-RST Rochester

8h 24m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

$949Delta

Thu, Nov 26 - Fri, Nov 27

Cheap last minute flights

Enter your travel dates to find the best prices.

1:02 pm - 6:08 pmRST Rochester-GSP Greenville

4h 06m1 stop Chicago O'Hare Intl

6:01 am - 12:32 pmGSP Greenville-RST Rochester

7h 31m1 stop Chicago O'Hare Intl

$554American Airlines

Sat, Oct 10 - Tue, Oct 13

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$560American Airlines

Sat, Oct 10 - Tue, Oct 13

1:02 pm - 11:21 pmRST Rochester-GSP Greenville

9h 19m2 stops Chicago O'Hare Intl Charlotte Douglas

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$585American Airlines

Sat, Oct 10 - Tue, Oct 13

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$587American Airlines

Sat, Oct 10 - Mon, Oct 12

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

6:43 pm - 12:07 amGSP Greenville-RST Rochester

6h 24m1 stop Chicago O'Hare Intl

$611American Airlines

Sat, Oct 10 - Mon, Oct 12

7:08 am - 6:36 pmRST Rochester-GSP Greenville

10h 28m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$612American Airlines

Sat, Oct 10 - Mon, Oct 12

7:08 am - 4:23 pmRST Rochester-GSP Greenville

8h 15m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$650American Airlines

Mon, Oct 5 - Mon, Oct 12

1:02 pm - 6:08 pmRST Rochester-GSP Greenville

4h 06m1 stop Chicago O'Hare Intl

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$672American Airlines

Mon, Oct 5 - Mon, Oct 12

1:02 pm - 11:21 pmRST Rochester-GSP Greenville

9h 19m2 stops Chicago O'Hare Intl Charlotte Douglas

6:43 pm - 12:07 amGSP Greenville-RST Rochester

6h 24m1 stop Chicago O'Hare Intl

$701American Airlines

Fri, Oct 9 - Tue, Oct 13

4:27 pm - 11:00 pmRST Rochester-GSP Greenville

5h 33m1 stop Chicago O'Hare Intl

4:55 pm - 12:07 amGSP Greenville-RST Rochester

8h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$701American Airlines

Sat, Oct 10 - Sun, Oct 11

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American Airlines flights from Rochester, Minnesota to South Carolina

Our best American Airlines deals on Rochester, Minnesota to South Carolina flight tickets

American Airlines

Nov 13

RST7:02 amRochester

7h 22m

1 stop

CHS3:24 pmCharleston

Nov 17

CHS7:13 amCharleston

5h 50m

1 stop

RST12:03 pmRochester

$338

American Airlines

Nov 13

RST7:02 amRochester

7h 22m

1 stop

CHS3:24 pmCharleston

Nov 17

CHS4:13 pmCharleston

8h 46m

2 stops

RST11:59 pmRochester

$344

American Airlines

Nov 13

RST12:34 pmRochester

9h 03m

2 stops

CHS10:37 pmCharleston

Nov 17

CHS2:40 pmCharleston

10h 19m

2 stops

RST11:59 pmRochester

$419

Delta flights from Rochester, Minnesota to South Carolina

Our best Delta deals on Rochester, Minnesota to South Carolina flight tickets

Delta

Oct 11

RST11:23 amRochester

10h 28m

2 stops

GSP10:51 pmGreenville

Oct 13

GSP5:40 amGreenville

6h 03m

2 stops

RST10:43 amRochester

$850

Delta

Nov 26

RST12:40 pmRochester

8h 32m

2 stops

GSP10:12 pmGreenville

Nov 29

GSP10:56 amGreenville

24h 17m

2 stops

RST10:13 amRochester

$858

Delta

Nov 26

RST12:40 pmRochester

8h 32m

2 stops

GSP10:12 pmGreenville

Nov 27

GSP8:11 amGreenville

8h 24m

2 stops

RST3:35 pmRochester

$949

momondo Fare Finder

Use the filters below to find and compare flights from Rochester, Minnesota to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterCharleston

RST Rochester - CHS Charleston

RSTCHS

Rochester

Fri 11/13

7:02 am-3:24 pm

1 stop7h 22m

Charleston

Tue 11/17

7:13 am-12:03 pm

1 stop5h 50m

$338

RochesterCharleston

RST Rochester - CHS Charleston

RSTCHS

Rochester

Fri 11/13

7:02 am-3:24 pm

1 stop7h 22m

Charleston

Tue 11/17

4:13 pm-11:59 pm

2 stops8h 46m

$344

RochesterCharleston

RST Rochester - CHS Charleston

RSTCHS

Rochester

Fri 11/13

12:34 pm-10:37 pm

2 stops9h 03m

Charleston

Tue 11/17

2:40 pm-11:59 pm

2 stops10h 19m

$419

RochesterMyrtle Beach

RST Rochester - MYR Myrtle Beach Intl

RSTMYR

Rochester

Sat 2/6

12:34 pm-10:58 pm

2 stops9h 24m

Myrtle Beach Intl

Sat 2/13

6:00 am-3:45 pm

2 stops10h 45m

$449

Quickest round-trip

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Thu 11/19

12:38 pm-5:57 pm

1 stop4h 19m

Greenville

Sun 11/22

6:27 pm-12:06 am

1 stop6h 39m

$478

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Sat 10/17

4:27 pm-11:00 pm

1 stop5h 33m

Greenville

Sat 10/24

6:43 pm-12:07 am

1 stop6h 24m

$484

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Thu 11/19

12:38 pm-5:57 pm

1 stop4h 19m

Greenville

Sun 11/22

3:58 pm-12:06 am

2 stops9h 08m

$484

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Sat 10/17

4:27 pm-11:00 pm

1 stop5h 33m

Greenville

Sat 10/24

7:17 am-3:46 pm

2 stops9h 29m

$490

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Thu 11/26

12:40 pm-10:12 pm

2 stops8h 32m

Greenville

Sun 11/29

10:56 am-10:13 am

2 stops24h 17m

$858

RochesterGreenville

RST Rochester - GSP Greenville

RSTGSP

Rochester

Thu 11/26

12:40 pm-10:12 pm

2 stops8h 32m

Greenville

Fri 11/27

8:11 am-3:35 pm

2 stops8h 24m

$949

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first

How to get the cheapest flight ticket from Rochester, Minnesota to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Rochester, Minnesota to South Carolina flights?

You could potentially save up to 34% on your flight if you consider stops on a Rochester, Minnesota to South Carolina flight.

Cheap Rochester, Minnesota to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester, Minnesota to South Carolina

Best Price Found	$258
Fastest flight time	4h 09m
Direct flights	None

The best one-way flight to South Carolina from Rochester, Minnesota in the past 72 hours is $258. The best round-trip flight deal from Rochester, Minnesota to South Carolina found on momondo in the last 72 hours is $338.

The fastest flight from Rochester, Minnesota to South Carolina takes 4h 09m

There are no direct flights from Rochester, Minnesota to South Carolina. There are no popular flight routes from Rochester, Minnesota to South Carolina.

Search flight deals

Frequently asked questions about flying from Rochester, Minnesota to South Carolina

When did momondo last update prices for flights from Rochester Airport to South Carolina?
Prices for flights from Rochester Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Rochester Airport to South Carolina?
The number of operators available for flights from Rochester Airport to South Carolina is 1 as of October 2026.
How old do you have to be to fly from Rochester Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Rochester Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Rochester, Minnesota to South Carolina

Compare and see reviews for airlines that fly from Rochester, Minnesota to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $288	Free Cancellation	Rating 7.0 12,132 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to South Carolina?

It is quick and easy to find Rochester to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Rochester to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Rochester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Rochester to South Carolina?

momondo helps you find the best flight between Rochester and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Rochester to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Rochester to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.