Cheap flights from Roanoke to St. Louis from $239

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to St. Louis departing on 8/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Roanoke to St. Louis

Cheap round-trip flights

Delta Logo
3:32 pm - 7:07 pmROA-STL
4h 35m1 stop
Delta Logo
6:42 pm - 12:25 amSTL-ROA
4h 43m1 stop
$249Delta
Find Deal
Sat, Sep 6 - Fri, Sep 12
Delta Logo
7:51 pm - 11:41 pmROA-STL
4h 50m1 stop
Delta Logo
6:52 pm - 12:09 amSTL-ROA
4h 17m1 stop
$279Delta
Find Deal
Thu, Oct 9 - Sun, Oct 12
Delta Logo
7:51 pm - 11:14 pmROA-STL
4h 23m1 stop
Delta Logo
6:49 pm - 12:32 amSTL-ROA
4h 43m1 stop
$284Delta
Find Deal
Thu, Aug 14 - Mon, Aug 18
American Airlines Logo
6:10 pm - 11:53 pmROA-STL
6h 43m1 stop
American Airlines Logo
6:00 am - 2:36 pmSTL-ROA
7h 36m1 stop
$319American Airlines
Find Deal
Sun, Sep 7 - Sat, Sep 13
United Airlines Logo
6:20 am - 3:44 pmROA-STL
10h 24m2 stops
United Airlines Logo
3:20 pm - 9:19 pmSTL-ROA
4h 59m1 stop
$374United Airlines
Find Deal
Sat, Sep 6 - Fri, Sep 12
American Airlines Logo
12:36 pm - 9:53 pmROA-STL
10h 17m2 stops
American Airlines Logo
5:27 am - 10:47 amSTL-ROA
4h 20m1 stop
$385American Airlines
Find Deal
Tue, Sep 9 - Sun, Sep 14
United Airlines Logo
10:30 am - 10:35 pmROA-STL
13h 05m2 stops
United Airlines Logo
3:23 pm - 9:41 pmSTL-ROA
5h 18m1 stop
$409United Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
4:07 pm - 7:18 pmROA-STL
4h 11m1 stop
American Airlines Logo
8:43 am - 4:59 pmSTL-ROA
7h 16m2 stops
$422American Airlines
Find Deal
Sat, Aug 30 - Tue, Sep 2
United Airlines Logo
5:40 pm - 9:32 pmROA-STL
4h 52m1 stop
United Airlines Logo
3:23 pm - 2:04 pmSTL-ROA
21h 41m2 stops
$434United Airlines
Find Deal
Tue, Sep 23 - Fri, Sep 26
American Airlines Logo
5:00 am - 8:13 amROA-STL
4h 13m1 stop
American Airlines Logo
7:32 am - 5:02 pmSTL-ROA
8h 30m2 stops
$457American Airlines
Find Deal
Fri, Aug 29 - Sun, Aug 31

United Airlines flights from Roanoke to St. Louis

Our best United Airlines deals on Roanoke to St. Louis flight tickets
United Airlines
Sep 6
ROA6:20 amRoanoke
10h 24m
2 stops
STL3:44 pmLambert-St Louis
Sep 12
STL3:20 pmLambert-St Louis
4h 59m
1 stop
ROA9:19 pmRoanoke
United Airlines
Oct 4
ROA10:30 amRoanoke
13h 05m
2 stops
STL10:35 pmLambert-St Louis
Oct 11
STL3:23 pmLambert-St Louis
5h 18m
1 stop
ROA9:41 pmRoanoke
United Airlines
Sep 23
ROA5:40 pmRoanoke
4h 52m
1 stop
STL9:32 pmLambert-St Louis
Sep 26
STL3:23 pmLambert-St Louis
21h 41m
2 stops
ROA2:04 pmRoanoke

Delta flights from Roanoke to St. Louis

Our best Delta deals on Roanoke to St. Louis flight tickets
Delta
Sep 6
ROA3:32 pmRoanoke
4h 35m
1 stop
STL7:07 pmLambert-St Louis
Sep 12
STL6:42 pmLambert-St Louis
4h 43m
1 stop
ROA12:25 amRoanoke
Delta
Oct 9
ROA7:51 pmRoanoke
4h 50m
1 stop
STL11:41 pmLambert-St Louis
Oct 12
STL6:52 pmLambert-St Louis
4h 17m
1 stop
ROA12:09 amRoanoke
Delta
Aug 14
ROA7:51 pmRoanoke
4h 23m
1 stop
STL11:14 pmLambert-St Louis
Aug 18
STL6:49 pmLambert-St Louis
4h 43m
1 stop
ROA12:32 amRoanoke

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Roanoke to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

3:32 pm-7:07 pm

1 stop4h 35m

Lambert-St Louis

Fri 9/12

6:42 pm-12:25 am

1 stop4h 43m

$249

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 10/9

7:51 pm-11:41 pm

1 stop4h 50m

Lambert-St Louis

Sun 10/12

6:52 pm-12:09 am

1 stop4h 17m

$279

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 8/14

7:51 pm-11:14 pm

1 stop4h 23m

Lambert-St Louis

Mon 8/18

6:49 pm-12:32 am

1 stop4h 43m

$284

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sun 9/7

6:10 pm-11:53 pm

1 stop6h 43m

Lambert-St Louis

Sat 9/13

6:00 am-2:36 pm

1 stop7h 36m

$319

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

6:20 am-3:44 pm

2 stops10h 24m

Lambert-St Louis

Fri 9/12

3:20 pm-9:19 pm

1 stop4h 59m

$374

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 9/9

12:36 pm-9:53 pm

2 stops10h 17m

Lambert-St Louis

Sun 9/14

5:27 am-10:47 am

1 stop4h 20m

$385

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 10/4

10:30 am-10:35 pm

2 stops13h 05m

Lambert-St Louis

Sat 10/11

3:23 pm-9:41 pm

1 stop5h 18m

$409

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 8/30

4:07 pm-7:18 pm

1 stop4h 11m

Lambert-St Louis

Tue 9/2

8:43 am-4:59 pm

2 stops7h 16m

$422

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 9/23

5:40 pm-9:32 pm

1 stop4h 52m

Lambert-St Louis

Fri 9/26

3:23 pm-2:04 pm

2 stops21h 41m

$434

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Fri 8/29

5:00 am-8:13 am

1 stop4h 13m

Lambert-St Louis

Sun 8/31

7:32 am-5:02 pm

2 stops8h 30m

$457

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Roanoke to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Roanoke to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $263. The month of March is another great option to travel to St. Louis, with average flight prices from Roanoke averaging around $336.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $316. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $582. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Roanoke in the evening is the least expensive time of day to depart. momondo users have found prices as low as $269 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $462 per ticket.

When to book flights from Roanoke to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to St. Louis (ROA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to St. Louis

Best Price Found

$239

Fastest flight time

4h 11m

Direct flights

None

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Roanoke in the past 72 hours is $239. The best round-trip flight deal from Roanoke to St. Louis found on momondo in the last 72 hours is $249.
The fastest flight from Roanoke to St. Louis takes 4h 11m
There are no direct flights from Roanoke to St. Louis. Popular non-direct route for this connection is Roanoke Airport - Lambert-St Louis Airport.
There is 1 airport near St. Louis: Lambert-St Louis (STL)

  • How far is Roanoke to Lambert-St Louis by plane?

    The straight-line distance from Roanoke to Lambert-St Louis is 565.9 mi. In terms of flight time, this usually takes a little over 4h 11m.

  • When did momondo last update prices for flights from Roanoke Airport to Lambert-St Louis Airport?

    Prices for flights from Roanoke Airport to Lambert-St Louis Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Roanoke Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The necessary travel and health documents for your Lambert-St Louis Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to St. Louis?


Best airlines flying from Roanoke to St. Louis

Compare and see reviews for airlines that fly from Roanoke to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
8.0
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $302Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
Florissant
Fenton
Collinsville
O'Fallon
Alton
St. Peters
Farmington
Wentzville
Festus
Glencoe
Eureka
Edwardsville
Clayton
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Roanoke.

Can I find flights from Roanoke to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Roanoke.

I’m not ready to book a flight from Roanoke to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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1 adult
Tue 8/5
Tue 8/12

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