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Cheap flights from Roanoke to Santa Fe from $404

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Santa Fe departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Roanoke to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:54 am - 7:26 pmROA  Roanoke-SAF Santa Fe
10h 32m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
3:11 pm - 10:47 pmSAF  Santa Fe-ROA Roanoke
5h 36m1 stop Dallas/Fort Worth
$404American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
8:50 am - 7:42 pmROA  Roanoke-SAF Santa Fe
12h 52m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
8:00 am - 9:15 pmSAF  Santa Fe-ROA Roanoke
11h 15m2 stops Dallas/Fort Worth Charlotte Douglas
$409American Airlines
Wed, Feb 3 - Sat, Feb 6
United Airlines Logo
10:44 am - 8:36 pmROA  Roanoke-SAF Santa Fe
11h 52m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
10:30 am - 8:59 pmSAF  Santa Fe-ROA Roanoke
8h 29m2 stops Denver Intl Chicago O'Hare Intl
$419United Airlines
Tue, Sep 1 - Sat, Sep 5
American Airlines Logo
7:00 am - 12:07 pmROA  Roanoke-SAF Santa Fe
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
6:48 am - 5:05 pmSAF  Santa Fe-ROA Roanoke
8h 17m1 stop Chicago O'Hare Intl
$464American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
12:33 pm - 9:58 pmROA  Roanoke-SAF Santa Fe
11h 25m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
6:48 am - 5:05 pmSAF  Santa Fe-ROA Roanoke
8h 17m1 stop Chicago O'Hare Intl
$474American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
12:33 pm - 9:58 pmROA  Roanoke-SAF Santa Fe
11h 25m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
7:10 am - 7:21 pmSAF  Santa Fe-ROA Roanoke
10h 11m2 stops Dallas/Fort Worth Charlotte Douglas
$479American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
6:52 am - 1:41 pmROA  Roanoke-SAF Santa Fe
8h 49m1 stop Dallas/Fort Worth
American Airlines Logo
3:11 pm - 10:47 pmSAF  Santa Fe-ROA Roanoke
5h 36m1 stop Dallas/Fort Worth
$486American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
9:21 am - 7:26 pmROA  Roanoke-SAF Santa Fe
12h 05m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
10:12 am - 11:44 pmSAF  Santa Fe-ROA Roanoke
11h 32m2 stops Dallas/Fort Worth Charlotte Douglas
$501American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
5:47 pm - 9:57 pmROA  Roanoke-SAF Santa Fe
6h 10m1 stop Chicago O'Hare Intl
American Airlines Logo
7:15 pm - 8:31 amSAF  Santa Fe-ROA Roanoke
11h 16m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
$515American Airlines
Sat, Oct 3 - Thu, Oct 8
American Airlines Logo
9:21 am - 7:26 pmROA  Roanoke-SAF Santa Fe
12h 05m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
10:12 am - 9:53 pmSAF  Santa Fe-ROA Roanoke
9h 41m2 stops Dallas/Fort Worth Charlotte Douglas
$534American Airlines
Sat, Oct 10 - Sat, Oct 17

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United Airlines flights from Roanoke to Santa Fe

Our best United Airlines deals on Roanoke to Santa Fe flight tickets
United Airlines
Sep 1
ROA10:44 amRoanoke
11h 52m
2 stops
SAF8:36 pmSanta Fe
Sep 5
SAF10:30 amSanta Fe
8h 29m
2 stops
ROA8:59 pmRoanoke
$419
United Airlines
Dec 5
ROA2:13 pmRoanoke
9h 48m
2 stops
SAF10:01 pmSanta Fe
Dec 9
SAF3:20 pmSanta Fe
20h 38m
2 stops
ROA1:58 pmRoanoke
$703
United Airlines
Jan 6
ROA10:20 amRoanoke
25h 12m
2 stops
SAF9:32 amSanta Fe
Jan 9
SAF1:20 pmSanta Fe
22h 38m
2 stops
ROA1:58 pmRoanoke
$784

American Airlines flights from Roanoke to Santa Fe

Our best American Airlines deals on Roanoke to Santa Fe flight tickets
American Airlines
Oct 10
ROA10:54 amRoanoke
10h 32m
2 stops
SAF7:26 pmSanta Fe
Oct 17
SAF3:11 pmSanta Fe
5h 36m
1 stop
ROA10:47 pmRoanoke
$404
American Airlines
Feb 3
ROA8:50 amRoanoke
12h 52m
2 stops
SAF7:42 pmSanta Fe
Feb 6
SAF8:00 amSanta Fe
11h 15m
2 stops
ROA9:15 pmRoanoke
$409
American Airlines
Aug 28
ROA7:00 amRoanoke
7h 07m
1 stop
SAF12:07 pmSanta Fe
Sep 1
SAF6:48 amSanta Fe
8h 17m
1 stop
ROA5:05 pmRoanoke
$464

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Roanoke to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Sat 10/10

10:54 am-7:26 pm

2 stops10h 32m

Santa Fe

Sat 10/17

3:11 pm-10:47 pm

1 stop5h 36m

$404

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Wed 2/3

8:50 am-7:42 pm

2 stops12h 52m

Santa Fe

Sat 2/6

8:00 am-9:15 pm

2 stops11h 15m

$409

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Tue 9/1

10:44 am-8:36 pm

2 stops11h 52m

Santa Fe

Sat 9/5

10:30 am-8:59 pm

2 stops8h 29m

$419

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Fri 8/28

7:00 am-12:07 pm

1 stop7h 07m

Santa Fe

Tue 9/1

6:48 am-5:05 pm

1 stop8h 17m

$464

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Fri 8/28

12:33 pm-9:58 pm

2 stops11h 25m

Santa Fe

Tue 9/1

6:48 am-5:05 pm

1 stop8h 17m

$474

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Fri 8/28

12:33 pm-9:58 pm

2 stops11h 25m

Santa Fe

Tue 9/1

7:10 am-7:21 pm

2 stops10h 11m

$479
Quickest round-trip

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Sat 10/10

6:52 am-1:41 pm

1 stop8h 49m

Santa Fe

Sat 10/17

3:11 pm-10:47 pm

1 stop5h 36m

$486

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Sat 10/10

9:21 am-7:26 pm

2 stops12h 05m

Santa Fe

Sat 10/17

10:12 am-11:44 pm

2 stops11h 32m

$501

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Sat 10/3

5:47 pm-9:57 pm

1 stop6h 10m

Santa Fe

Thu 10/8

7:15 pm-8:31 am

2 stops11h 16m

$515

RoanokeSanta Fe

ROA Roanoke - SAF Santa Fe

ROASAF

Roanoke

Sat 10/10

9:21 am-7:26 pm

2 stops12h 05m

Santa Fe

Sat 10/17

10:12 am-9:53 pm

2 stops9h 41m

$534

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Roanoke to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Roanoke to Santa Fe?

American Airlines and United Airlines are the most popular carriers operating from Roanoke to Santa Fe

What airlines fly to Santa Fe?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Santa Fe from Roanoke according to our data. Delta is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Santa Fe. Keep in mind that there are 3 different airlines that fly to Santa Fe on a routine basis, so you have a few additional options to choose from.

When to book flights from Roanoke to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Fe (ROA to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Fe

Best Price Found

$470

Fastest flight time

9h 01m

Direct flights

None
The best one-way flight to Santa Fe from Roanoke in the past 72 hours is $470. The best round-trip flight deal from Roanoke to Santa Fe found on momondo in the last 72 hours is $404.
The fastest flight from Roanoke to Santa Fe takes 9h 01m
There are no direct flights from Roanoke to Santa Fe. There are no popular flight routes from Roanoke to Santa Fe.
Search flight deals

Frequently asked questions about flying from Roanoke to Santa Fe

  • How far is Roanoke to Santa Fe by plane?

    Santa Fe is 1442.9 mi away from Roanoke. By plane, this route typically takes 9h 01m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Fe Airport?

    Prices for flights from Roanoke Airport to Santa Fe Airport refresh daily.

  • How old do you have to be to fly from Roanoke Airport to Santa Fe Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Fe?

It is quick and easy to find Roanoke to Santa Fe flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Fe that suits you.

Can I find flights from Roanoke to Santa Fe with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Fe from Roanoke which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Roanoke to Santa Fe?

momondo helps you find the best flight between Roanoke and Santa Fe by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Roanoke to Santa Fe right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Roanoke to Santa Fe now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Fe and let you know when they change.

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