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Cheap flights from Roanoke to Panama City from $269

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Panama City departing on 6/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Roanoke to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 8:17 am
ROA
-
ECP
3h 17m
1 stop
Delta Logo
7:05 pm - 11:49 pm
ECP
-
ROA
3h 44m
1 stop
$269Delta
Thu, Jun 11 - Sun, Jun 14
Delta Logo
6:00 am - 8:39 am
ROA
-
ECP
3h 39m
1 stop
Delta Logo
6:06 pm - 12:06 am
ECP
-
ROA
5h 00m
1 stop
$274Delta
Wed, Feb 11 - Thu, Feb 19
Delta Logo
7:05 am - 11:48 am
ROA
-
ECP
5h 43m
1 stop
Delta Logo
6:43 pm - 12:19 am
ECP
-
ROA
4h 36m
1 stop
$279Delta
Mon, Mar 23 - Mon, Mar 30
Delta Logo
6:00 am - 8:40 am
ROA
-
ECP
3h 40m
1 stop
Delta Logo
6:43 pm - 12:19 am
ECP
-
ROA
4h 36m
1 stop
$284Delta
Sun, Mar 22 - Mon, Mar 30
Delta Logo
6:00 am - 8:17 am
ROA
-
ECP
3h 17m
1 stop
Delta Logo
7:05 pm - 11:49 pm
ECP
-
ROA
3h 44m
1 stop
$294Delta
Fri, Jun 19 - Fri, Jun 26
Delta Logo
7:05 am - 12:10 pm
ROA
-
ECP
6h 05m
1 stop
Delta Logo
6:00 am - 10:30 am
ECP
-
ROA
3h 30m
1 stop
$299Delta
Tue, Feb 10 - Wed, Feb 18
Delta Logo
6:00 am - 8:17 am
ROA
-
ECP
3h 17m
1 stop
Delta Logo
6:00 am - 10:35 am
ECP
-
ROA
3h 35m
1 stop
$343Delta
Wed, May 27 - Sun, May 31
Delta Logo
6:00 am - 8:40 am
ROA
-
ECP
3h 40m
1 stop
Delta Logo
6:43 pm - 12:04 am
ECP
-
ROA
4h 21m
1 stop
$344Delta
Thu, Apr 2 - Thu, Apr 9
American Airlines Logo
8:02 pm - 11:41 pm
ROA
-
ECP
4h 39m
1 stop
American Airlines Logo
6:43 pm - 11:43 pm
ECP
-
ROA
4h 00m
1 stop
$348American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
12:43 pm - 5:33 pm
ROA
-
ECP
5h 50m
1 stop
American Airlines Logo
7:19 am - 8:30 pm
ECP
-
ROA
12h 11m
2 stops
$367American Airlines
Wed, Feb 11 - Thu, Feb 19

American Airlines flights from Roanoke to Panama City, Florida

Our best American Airlines deals on Roanoke to Panama City, Florida flight tickets
American Airlines
May 27
ROA8:02 pmRoanoke
4h 39m
1 stop
ECP11:41 pmPanama City NW Florida Beaches
May 31
ECP6:43 pmPanama City NW Florida Beaches
4h 00m
1 stop
ROA11:43 pmRoanoke
$348
American Airlines
Feb 11
ROA12:43 pmRoanoke
5h 50m
1 stop
ECP5:33 pmPanama City NW Florida Beaches
Feb 19
ECP7:19 amPanama City NW Florida Beaches
12h 11m
2 stops
ROA8:30 pmRoanoke
$367
American Airlines
Mar 21
ROA8:00 pmRoanoke
4h 49m
1 stop
ECP11:49 pmPanama City NW Florida Beaches
Mar 25
ECP4:34 pmPanama City NW Florida Beaches
6h 11m
1 stop
ROA11:45 pmRoanoke
$371

Delta flights from Roanoke to Panama City, Florida

Our best Delta deals on Roanoke to Panama City, Florida flight tickets
Delta
Jun 11
ROA6:00 amRoanoke
3h 17m
1 stop
ECP8:17 amPanama City NW Florida Beaches
Jun 14
ECP7:05 pmPanama City NW Florida Beaches
3h 44m
1 stop
ROA11:49 pmRoanoke
$269
Delta
Feb 11
ROA6:00 amRoanoke
3h 39m
1 stop
ECP8:39 amPanama City NW Florida Beaches
Feb 19
ECP6:06 pmPanama City NW Florida Beaches
5h 00m
1 stop
ROA12:06 amRoanoke
$274
Delta
Mar 23
ROA7:05 amRoanoke
5h 43m
1 stop
ECP11:48 amPanama City NW Florida Beaches
Mar 30
ECP6:43 pmPanama City NW Florida Beaches
4h 36m
1 stop
ROA12:19 amRoanoke
$279

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 6/11

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Sun 6/14

7:05 pm-11:49 pm

1 stop3h 44m

$269

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 2/11

6:00 am-8:39 am

1 stop3h 39m

Panama City NW Florida Beaches

Thu 2/19

6:06 pm-12:06 am

1 stop5h 00m

$274

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Mon 3/23

7:05 am-11:48 am

1 stop5h 43m

Panama City NW Florida Beaches

Mon 3/30

6:43 pm-12:19 am

1 stop4h 36m

$279

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sun 3/22

6:00 am-8:40 am

1 stop3h 40m

Panama City NW Florida Beaches

Mon 3/30

6:43 pm-12:19 am

1 stop4h 36m

$284

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 6/19

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Fri 6/26

7:05 pm-11:49 pm

1 stop3h 44m

$294

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 2/10

7:05 am-12:10 pm

1 stop6h 05m

Panama City NW Florida Beaches

Wed 2/18

6:00 am-10:30 am

1 stop3h 30m

$299

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 5/27

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Sun 5/31

6:00 am-10:35 am

1 stop3h 35m

$343

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 4/2

6:00 am-8:40 am

1 stop3h 40m

Panama City NW Florida Beaches

Thu 4/9

6:43 pm-12:04 am

1 stop4h 21m

$344

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 5/27

8:02 pm-11:41 pm

1 stop4h 39m

Panama City NW Florida Beaches

Sun 5/31

6:43 pm-11:43 pm

1 stop4h 00m

$348

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 2/11

12:43 pm-5:33 pm

1 stop5h 50m

Panama City NW Florida Beaches

Thu 2/19

7:19 am-8:30 pm

2 stops12h 11m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Roanoke to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Roanoke is in August. Flight prices, which tend to average around $253, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Panama City, Florida, with average flight prices from Roanoke averaging around $271.

When to book flights from Roanoke to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Panama City, Florida (ROA to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Panama City, Florida

Fastest flight time

3h 15m

Direct flights

None
The fastest flight from Roanoke to Panama City, Florida takes 3h 15m
There are no direct flights from Roanoke to Panama City, Florida. There are no popular flight routes from Roanoke to Panama City, Florida.
Search flight deals

  • How far is Roanoke to Panama City NW Florida Beaches by plane?

    A flight from Roanoke to Panama City NW Florida Beaches will travel around 590.4 mi. Typically, this will take 3h 15m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Roanoke Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Roanoke Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Roanoke Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Roanoke to Panama City, Florida?

Best airlines flying from Roanoke to Panama City, Florida

Compare and see reviews for airlines that fly from Roanoke to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,128 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Roanoke to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Roanoke to Panama City with flexible booking policies on momondo?

Flights from Roanoke to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Roanoke to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Roanoke to Panama City.

I’m not ready to book a flight from Roanoke to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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