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Cheap flights from Roanoke to Panama City from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Panama City departing on 5/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Roanoke to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:50 pm - 11:12 pm
ROA
-
ECP
4h 22m
1 stop
Delta Logo
5:10 pm - 12:25 am
ECP
-
ROA
6h 15m
1 stop
$326Delta
Sat, Apr 18 - Wed, Apr 22
Delta Logo
6:00 am - 8:17 am
ROA
-
ECP
3h 17m
1 stop
Delta Logo
7:05 pm - 11:49 pm
ECP
-
ROA
3h 44m
1 stop
$329Delta
Fri, Jun 19 - Fri, Jun 26
Delta Logo
7:51 pm - 11:04 pm
ROA
-
ECP
4h 13m
1 stop
Delta Logo
6:00 am - 10:27 am
ECP
-
ROA
3h 27m
1 stop
$339Delta
Sat, Apr 4 - Wed, Apr 8
Delta Logo
7:05 am - 12:19 pm
ROA
-
ECP
6h 14m
1 stop
Delta Logo
5:49 am - 10:28 am
ECP
-
ROA
3h 39m
1 stop
$351Delta
Tue, Apr 21 - Sat, Apr 25
Delta Logo
7:50 pm - 11:12 pm
ROA
-
ECP
4h 22m
1 stop
Delta Logo
5:10 pm - 12:25 am
ECP
-
ROA
6h 15m
1 stop
$354Delta
Sat, Apr 18 - Tue, Apr 28
Delta Logo
7:05 am - 12:19 pm
ROA
-
ECP
6h 14m
1 stop
Delta Logo
5:10 pm - 12:25 am
ECP
-
ROA
6h 15m
1 stop
$361Delta
Wed, Apr 15 - Wed, Apr 22
Delta Logo
7:05 am - 12:19 pm
ROA
-
ECP
6h 14m
1 stop
Delta Logo
5:49 am - 10:28 am
ECP
-
ROA
3h 39m
1 stop
$364Delta
Wed, Apr 15 - Thu, Apr 23
Delta Logo
7:05 am - 12:19 pm
ROA
-
ECP
6h 14m
1 stop
Delta Logo
5:10 pm - 12:25 am
ECP
-
ROA
6h 15m
1 stop
$389Delta
Wed, Apr 15 - Tue, Apr 28
Delta Logo
7:05 am - 11:44 am
ROA
-
ECP
5h 39m
1 stop
Delta Logo
6:41 pm - 12:29 am
ECP
-
ROA
4h 48m
1 stop
$394Delta
Sat, Jun 6 - Thu, Jun 11
American Airlines Logo
7:58 pm - 11:37 pm
ROA
-
ECP
4h 39m
1 stop
American Airlines Logo
1:17 pm - 7:50 pm
ECP
-
ROA
5h 33m
1 stop
$399American Airlines
Sat, Jul 11 - Sat, Jul 18

United Airlines flights from Roanoke to Panama City, Florida

Our best United Airlines deals on Roanoke to Panama City, Florida flight tickets
United Airlines
Jul 3
ROA6:40 amRoanoke
7h 41m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
Jul 9
ECP10:25 amPanama City NW Florida Beaches
12h 19m
2 stops
ROA11:44 pmRoanoke
$402
United Airlines
Jul 4
ROA6:47 amRoanoke
7h 34m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
Jul 8
ECP10:25 amPanama City NW Florida Beaches
5h 39m
1 stop
ROA5:04 pmRoanoke
$403
United Airlines
Jul 4
ROA6:47 amRoanoke
7h 34m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
Jul 8
ECP10:25 amPanama City NW Florida Beaches
12h 19m
2 stops
ROA11:44 pmRoanoke
$408

Delta flights from Roanoke to Panama City, Florida

Our best Delta deals on Roanoke to Panama City, Florida flight tickets
Delta
Apr 18
ROA7:50 pmRoanoke
4h 22m
1 stop
ECP11:12 pmPanama City NW Florida Beaches
Apr 22
ECP5:10 pmPanama City NW Florida Beaches
6h 15m
1 stop
ROA12:25 amRoanoke
$326
Delta
Jun 19
ROA6:00 amRoanoke
3h 17m
1 stop
ECP8:17 amPanama City NW Florida Beaches
Jun 26
ECP7:05 pmPanama City NW Florida Beaches
3h 44m
1 stop
ROA11:49 pmRoanoke
$329
Delta
Apr 4
ROA7:51 pmRoanoke
4h 13m
1 stop
ECP11:04 pmPanama City NW Florida Beaches
Apr 8
ECP6:00 amPanama City NW Florida Beaches
3h 27m
1 stop
ROA10:27 amRoanoke
$339

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sat 4/18

7:50 pm-11:12 pm

1 stop4h 22m

Panama City NW Florida Beaches

Wed 4/22

5:10 pm-12:25 am

1 stop6h 15m

$326
Quickest round-trip

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 6/19

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Fri 6/26

7:05 pm-11:49 pm

1 stop3h 44m

$329

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sat 4/4

7:51 pm-11:04 pm

1 stop4h 13m

Panama City NW Florida Beaches

Wed 4/8

6:00 am-10:27 am

1 stop3h 27m

$339

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 4/21

7:05 am-12:19 pm

1 stop6h 14m

Panama City NW Florida Beaches

Sat 4/25

5:49 am-10:28 am

1 stop3h 39m

$351

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sat 4/18

7:50 pm-11:12 pm

1 stop4h 22m

Panama City NW Florida Beaches

Tue 4/28

5:10 pm-12:25 am

1 stop6h 15m

$354

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 4/15

7:05 am-12:19 pm

1 stop6h 14m

Panama City NW Florida Beaches

Wed 4/22

5:10 pm-12:25 am

1 stop6h 15m

$361

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 4/15

7:05 am-12:19 pm

1 stop6h 14m

Panama City NW Florida Beaches

Thu 4/23

5:49 am-10:28 am

1 stop3h 39m

$364

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 4/15

7:05 am-12:19 pm

1 stop6h 14m

Panama City NW Florida Beaches

Tue 4/28

5:10 pm-12:25 am

1 stop6h 15m

$389

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sat 6/6

7:05 am-11:44 am

1 stop5h 39m

Panama City NW Florida Beaches

Thu 6/11

6:41 pm-12:29 am

1 stop4h 48m

$394

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sat 7/11

7:58 pm-11:37 pm

1 stop4h 39m

Panama City NW Florida Beaches

Sat 7/18

1:17 pm-7:50 pm

1 stop5h 33m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Roanoke to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Roanoke is in August. Flight prices, which tend to average around $253, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Panama City, Florida, with average flight prices from Roanoke averaging around $298.

When to book flights from Roanoke to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Panama City, Florida (ROA to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Panama City, Florida

Fastest flight time

3h 14m

Direct flights

None
The fastest flight from Roanoke to Panama City, Florida takes 3h 14m
There are no direct flights from Roanoke to Panama City, Florida. There are no popular flight routes from Roanoke to Panama City, Florida.
Search flight deals

  • How far is Roanoke to Panama City NW Florida Beaches by plane?

    A flight from Roanoke to Panama City NW Florida Beaches will travel around 590.4 mi. Typically, this will take 3h 14m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Roanoke Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Roanoke Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Roanoke Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Roanoke to Panama City, Florida?

Best airlines flying from Roanoke to Panama City, Florida

Compare and see reviews for airlines that fly from Roanoke to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,319 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Roanoke to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Roanoke to Panama City with flexible booking policies on momondo?

Flights from Roanoke to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Roanoke to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Roanoke to Panama City.

I’m not ready to book a flight from Roanoke to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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