Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Roanoke to Knoxville from $240

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Knoxville departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Roanoke to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:59 am - 5:37 pm
ROA
-
TYS
5h 38m
1 stop
American Airlines Logo
5:00 am - 10:37 am
TYS
-
ROA
5h 37m
1 stop
$289American Airlines
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
2:54 pm - 6:13 pm
ROA
-
TYS
3h 19m
1 stop
American Airlines Logo
5:00 am - 8:36 am
TYS
-
ROA
3h 36m
1 stop
$291American Airlines
Sat, Apr 11 - Fri, Apr 17
American Airlines Logo
8:15 am - 5:37 pm
ROA
-
TYS
9h 22m
2 stops
American Airlines Logo
7:02 am - 10:37 am
TYS
-
ROA
3h 35m
1 stop
$304American Airlines
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
8:00 pm - 11:50 pm
ROA
-
TYS
3h 50m
1 stop
American Airlines Logo
5:00 am - 9:46 am
TYS
-
ROA
4h 46m
1 stop
$309American Airlines
Fri, Apr 3 - Tue, Apr 7
American Airlines Logo
5:00 am - 8:42 am
ROA
-
TYS
3h 42m
1 stop
American Airlines Logo
5:00 am - 12:33 pm
TYS
-
ROA
7h 33m
2 stops
$314American Airlines
Fri, Apr 3 - Tue, Apr 7
Delta Logo
6:00 am - 11:09 am
ROA
-
TYS
5h 09m
1 stop
Delta Logo
7:33 pm - 12:34 am
TYS
-
ROA
5h 01m
1 stop
$324Delta
Wed, May 20 - Wed, May 27
Delta Logo
6:00 am - 11:09 am
ROA
-
TYS
5h 09m
1 stop
Delta Logo
7:33 pm - 12:34 am
TYS
-
ROA
5h 01m
1 stop
$333Delta
Wed, May 20 - Wed, May 27
Delta Logo
6:00 am - 11:09 am
ROA
-
TYS
5h 09m
1 stop
Delta Logo
7:33 pm - 12:34 am
TYS
-
ROA
5h 01m
1 stop
$359Delta
Wed, May 20 - Wed, May 27
Allegiant Air Logo
3:18 pm - 10:43 pm
ROA
-
TYS
7h 25m
1 stop
Allegiant Air Logo
8:40 am - 9:10 pm
TYS
-
ROA
12h 30m
1 stop
$360Allegiant Air
Thu, Apr 2 - Mon, Apr 6
United Airlines Logo
6:00 am - 10:49 am
ROA
-
TYS
4h 49m
1 stop
United Airlines Logo
6:30 am - 2:00 pm
TYS
-
ROA
7h 30m
2 stops
$369United Airlines
Wed, May 20 - Wed, May 27

Delta flights from Roanoke to Knoxville

Our best Delta deals on Roanoke to Knoxville flight tickets
Delta
May 20
ROA6:00 amRoanoke
5h 09m
1 stop
TYS11:09 amKnoxville McGhee Tyson
May 27
TYS7:33 pmKnoxville McGhee Tyson
5h 01m
1 stop
ROA12:34 amRoanoke
$324
Delta
May 20
ROA6:00 amRoanoke
5h 09m
1 stop
TYS11:09 amKnoxville McGhee Tyson
May 27
TYS7:33 pmKnoxville McGhee Tyson
5h 01m
1 stop
ROA12:34 amRoanoke
$333
Delta
May 20
ROA6:00 amRoanoke
5h 09m
1 stop
TYS11:09 amKnoxville McGhee Tyson
May 27
TYS7:33 pmKnoxville McGhee Tyson
5h 01m
1 stop
ROA12:34 amRoanoke
$359

American Airlines flights from Roanoke to Knoxville

Our best American Airlines deals on Roanoke to Knoxville flight tickets
American Airlines
Mar 31
ROA11:59 amRoanoke
5h 38m
1 stop
TYS5:37 pmKnoxville McGhee Tyson
Apr 4
TYS5:00 amKnoxville McGhee Tyson
5h 37m
1 stop
ROA10:37 amRoanoke
$289
American Airlines
Apr 11
ROA2:54 pmRoanoke
3h 19m
1 stop
TYS6:13 pmKnoxville McGhee Tyson
Apr 17
TYS5:00 amKnoxville McGhee Tyson
3h 36m
1 stop
ROA8:36 amRoanoke
$291
American Airlines
Mar 31
ROA8:15 amRoanoke
9h 22m
2 stops
TYS5:37 pmKnoxville McGhee Tyson
Apr 4
TYS7:02 amKnoxville McGhee Tyson
3h 35m
1 stop
ROA10:37 amRoanoke
$304

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 3/31

11:59 am-5:37 pm

1 stop5h 38m

Knoxville McGhee Tyson

Sat 4/4

5:00 am-10:37 am

1 stop5h 37m

$289
Quickest round-trip

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 4/11

2:54 pm-6:13 pm

1 stop3h 19m

Knoxville McGhee Tyson

Fri 4/17

5:00 am-8:36 am

1 stop3h 36m

$291

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 3/31

8:15 am-5:37 pm

2 stops9h 22m

Knoxville McGhee Tyson

Sat 4/4

7:02 am-10:37 am

1 stop3h 35m

$304

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 4/3

8:00 pm-11:50 pm

1 stop3h 50m

Knoxville McGhee Tyson

Tue 4/7

5:00 am-9:46 am

1 stop4h 46m

$309

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 4/3

5:00 am-8:42 am

1 stop3h 42m

Knoxville McGhee Tyson

Tue 4/7

5:00 am-12:33 pm

2 stops7h 33m

$314

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

6:00 am-11:09 am

1 stop5h 09m

Knoxville McGhee Tyson

Wed 5/27

7:33 pm-12:34 am

1 stop5h 01m

$324

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

6:00 am-11:09 am

1 stop5h 09m

Knoxville McGhee Tyson

Wed 5/27

7:33 pm-12:34 am

1 stop5h 01m

$333

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

6:00 am-11:09 am

1 stop5h 09m

Knoxville McGhee Tyson

Wed 5/27

7:33 pm-12:34 am

1 stop5h 01m

$359

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 4/2

3:18 pm-10:43 pm

1 stop7h 25m

Knoxville McGhee Tyson

Mon 4/6

8:40 am-9:10 pm

1 stop12h 30m

$360

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

6:00 am-10:49 am

1 stop4h 49m

Knoxville McGhee Tyson

Wed 5/27

6:30 am-2:00 pm

2 stops7h 30m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Roanoke to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Roanoke to Knoxville McGhee Tyson?

Allegiant Air and United Airlines are the most popular carriers operating from Roanoke to Knoxville McGhee Tyson

When to book flights from Roanoke to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Knoxville (ROA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Knoxville

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Roanoke to Knoxville takes 4h 06m
There are no direct flights from Roanoke to Knoxville. There are no popular flight routes from Roanoke to Knoxville.
Search flight deals

  • How far is Roanoke to Knoxville McGhee Tyson by plane?

    The distance between Roanoke and Knoxville McGhee Tyson is about 238.3 mi. In terms of flight time, this usually takes a little over 4h 06m.

  • When did momondo last update prices for flights from Roanoke Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Roanoke Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Roanoke Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Roanoke Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Knoxville for you.

Can I find flights from Roanoke to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Roanoke with this policy.

How can momondo help me find flights from Roanoke to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Roanoke.

I’m not ready to book a flight from Roanoke to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Roanoke and alert you when they change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 4/19
Sun 4/26
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States