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Cheap flights from Raleigh to South America from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to South America departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Raleigh to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
3:09 pm - 8:18 amRDU-MDE
17h 09m1 stop
Copa Airlines Logo
5:00 am - 1:15 pmMDE-RDU
8h 15m1 stop
$285Copa Airlines
Find Deal
Sun, Jan 11 - Fri, Jan 30
Spirit Airlines Logo
5:50 pm - 1:09 amRDU-MDE
7h 19m1 stop
Spirit Airlines Logo
2:25 am - 4:55 pmMDE-RDU
14h 30m1 stop
$288Spirit Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
American Airlines Logo
6:00 am - 9:10 pmRDU-MDE
15h 10m1 stop
American Airlines Logo
7:00 am - 9:39 pmMDE-RDU
14h 39m1 stop
$297American Airlines
Find Deal
Fri, Feb 6 - Tue, Feb 10
American Airlines Logo
7:35 pm - 3:30 pmRDU-CTG
19h 55m2 stops
American Airlines Logo
4:30 pm - 12:17 pmCTG-RDU
19h 47m2 stops
$301American Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9
United Airlines Logo
6:15 am - 10:05 pmRDU-MDE
15h 50m1 stop
United Airlines Logo
10:45 am - 10:30 pmMDE-RDU
11h 45m1 stop
$303United Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9
United Airlines Logo
6:15 am - 10:05 pmRDU-MDE
15h 50m1 stop
United Airlines Logo
10:45 am - 2:06 pmMDE-RDU
27h 21m3 stops
$308United Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9
Delta Logo
7:51 pm - 2:15 pmRDU-CTG
18h 24m1 stop
Delta Logo
3:30 pm - 12:11 amCTG-RDU
8h 41m1 stop
$322Delta
Find Deal
Sun, Feb 22 - Fri, Mar 6
Delta Logo
12:30 pm - 2:15 pmRDU-CTG
25h 45m1 stop
Delta Logo
4:35 am - 10:44 pmCTG-RDU
18h 09m2 stops
$326Delta
Find Deal
Sun, Feb 22 - Thu, Mar 5
LATAM Airlines Logo
7:15 am - 7:30 pmRDU-BOG
12h 15m1 stop
LATAM Airlines Logo
10:55 am - 8:25 pmBOG-RDU
9h 30m1 stop
$335LATAM Airlines
Find Deal
Tue, Nov 25 - Sat, Dec 6
LATAM Airlines Logo
7:15 am - 2:25 pmRDU-BOG
7h 10m1 stop
LATAM Airlines Logo
10:55 am - 8:25 pmBOG-RDU
9h 30m1 stop
$339LATAM Airlines
Find Deal
Tue, Nov 25 - Sat, Dec 6

United Airlines flights from Raleigh to South America

Our best United Airlines deals on Raleigh to South America flight tickets
United Airlines
Feb 5
RDU6:15 amRaleigh-Durham
15h 50m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 9
MDE10:45 amMedellín Jose Maria Cordova Intl
11h 45m
1 stop
RDU10:30 pmRaleigh-Durham
$303
Find similar
United Airlines
Feb 5
RDU6:15 amRaleigh-Durham
15h 50m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 9
MDE10:45 amMedellín Jose Maria Cordova Intl
27h 21m
3 stops
RDU2:06 pmRaleigh-Durham
$308
Find similar
United Airlines
Feb 13
RDU4:47 pmRaleigh-Durham
29h 48m
1 stop
BOG10:35 pmBogotá El Dorado
Feb 16
BOG1:30 amBogotá El Dorado
14h 10m
1 stop
RDU3:40 pmRaleigh-Durham
$310
Find similar

American Airlines flights from Raleigh to South America

Our best American Airlines deals on Raleigh to South America flight tickets
American Airlines
Feb 6
RDU6:00 amRaleigh-Durham
15h 10m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
Feb 10
MDE7:00 amMedellín Jose Maria Cordova Intl
14h 39m
1 stop
RDU9:39 pmRaleigh-Durham
$297
Find similar
American Airlines
Feb 5
RDU7:35 pmRaleigh-Durham
19h 55m
2 stops
CTG3:30 pmCartagena Rafael Nunez
Feb 9
CTG4:30 pmCartagena Rafael Nunez
19h 47m
2 stops
RDU12:17 pmRaleigh-Durham
$301
Find similar
American Airlines
Feb 6
RDU6:00 amRaleigh-Durham
15h 10m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
Feb 10
MDE7:00 amMedellín Jose Maria Cordova Intl
13h 43m
2 stops
RDU8:43 pmRaleigh-Durham
$302
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Raleigh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Raleigh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 1/11

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

Fri 1/30

5:00 am-1:15 pm

1 stop8h 15m

$285

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 12/15

5:50 pm-1:09 am

1 stop7h 19m

Medellín Jose Maria Cordova Intl

Mon 12/22

2:25 am-4:55 pm

1 stop14h 30m

$288

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 2/6

6:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Tue 2/10

7:00 am-9:39 pm

1 stop14h 39m

$297

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 2/5

7:35 pm-3:30 pm

2 stops19h 55m

Cartagena Rafael Nunez

Mon 2/9

4:30 pm-12:17 pm

2 stops19h 47m

$301

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 2/5

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Mon 2/9

10:45 am-10:30 pm

1 stop11h 45m

$303

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 2/5

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Mon 2/9

10:45 am-2:06 pm

3 stops27h 21m

$308

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sun 2/22

7:51 pm-2:15 pm

1 stop18h 24m

Cartagena Rafael Nunez

Fri 3/6

3:30 pm-12:11 am

1 stop8h 41m

$322

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sun 2/22

12:30 pm-2:15 pm

1 stop25h 45m

Cartagena Rafael Nunez

Thu 3/5

4:35 am-10:44 pm

2 stops18h 09m

$326

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 11/25

7:15 am-7:30 pm

1 stop12h 15m

Bogotá El Dorado

Sat 12/6

10:55 am-8:25 pm

1 stop9h 30m

$335

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 11/25

7:15 am-2:25 pm

1 stop7h 10m

Bogotá El Dorado

Sat 12/6

10:55 am-8:25 pm

1 stop9h 30m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Raleigh to South America is on a Monday when prices can be found for as low as $594. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to South America for around $711.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Raleigh to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $521. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $742 on average. Flights to South America from Raleigh at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $597 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $558 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Direct flights

None
There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.
Search flight deals

  • When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

    Prices for flights from Raleigh-Durham Airport to South America refresh daily.

  • How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

  • How old do you have to be to fly from Raleigh-Durham Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $164Free CancellationRating
7.9
8,003 reviews
Search Delta flights
LATAM AirlinesPriceFrom $225Free CancellationRating
7.5
1,878 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $245Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
Spirit AirlinesPriceFrom $260Free CancellationRating
6.3
8,151 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $283Free CancellationRating
7.2
11,044 reviews
Search American Airlines flights
United AirlinesPriceFrom $314Free CancellationRating
7.4
9,019 reviews
Search United Airlines flights
JetBluePriceFrom $374Free CancellationRating
7.2
2,903 reviews
Search JetBlue flights
GOLPriceFrom $540Free CancellationRating
7.3
1,129 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $300
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Flights to Rio de Janeirofrom $451
Flights to Medellínfrom $166
Flights to Santiagofrom $356
Flights to Cartagenafrom $167
Flights to Quitofrom $231
Flights to Cuscofrom $426
Flights to Guayaquilfrom $208
Flights to Califrom $187