What is the cheapest airline that flies from Raleigh-Durham to South America?

Spirit Airlines, Copa Airlines, and American Airlines are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Delta and Copa Airlines are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 28% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of February 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$100 Cheap Flights from Raleigh to South America in 2026

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Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:58 pm - 12:42 am

RDU

MDE

6h 44m

1 stop

1:37 am - 6:03 pm

MDE

RDU

15h 26m

1 stop

$261Spirit Airlines

Thu, Apr 16 - Sun, Apr 26

3:12 pm - 10:55 pm

RDU

BOG

7h 43m

1 stop

6:10 am - 1:23 pm

BOG

RDU

7h 13m

1 stop

$263Copa Airlines

Wed, Feb 25 - Wed, Mar 4

6:06 am - 1:30 pm

RDU

CTG

7h 24m

1 stop

4:30 pm - 11:59 pm

CTG

RDU

7h 29m

1 stop

$271American Airlines

Mon, Feb 23 - Thu, Feb 26

8:13 pm - 12:09 pm

RDU

CTG

16h 56m

2 stops

1:25 pm - 9:30 pm

CTG

RDU

7h 05m

1 stop

$276American Airlines

Sat, May 16 - Thu, May 21

12:45 pm - 7:30 pm

RDU

BOG

7h 45m

1 stop

8:35 am - 5:29 pm

BOG

RDU

7h 54m

1 stop

$301LATAM Airlines

Thu, Mar 12 - Wed, Mar 18

6:20 am - 9:35 pm

RDU

UIO

15h 15m

1 stop

7:05 am - 7:56 pm

UIO

RDU

11h 51m

2 stops

$386LATAM Airlines

Mon, Mar 2 - Thu, Mar 12

3:18 pm - 5:02 am

RDU

UIO

13h 44m

2 stops

7:00 pm - 2:13 pm

UIO

RDU

19h 13m

2 stops

$406Delta

Mon, Feb 23 - Sun, Mar 1

6:15 am - 8:35 pm

RDU

UIO

15h 20m

1 stop

7:00 pm - 7:56 pm

UIO

RDU

23h 56m

1 stop

$407Delta

Thu, Mar 19 - Mon, Mar 23

10:30 am - 10:20 am

RDU

GRU

22h 50m

1 stop

9:30 pm - 9:34 am

GRU

RDU

13h 04m

1 stop

$592United Airlines

Mon, Mar 23 - Thu, Mar 26

1:27 pm - 7:15 am

RDU

GRU

16h 48m

1 stop

9:30 pm - 11:44 pm

GRU

RDU

27h 14m

1 stop

$594United Airlines

Mon, Mar 23 - Thu, Mar 26

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

Feb 15

RDU8:08 amRaleigh-Durham

8h 37m

1 stop

BOG4:45 pmBogotá El Dorado

Feb 19

BOG10:55 amBogotá El Dorado

9h 05m

1 stop

RDU8:00 pmRaleigh-Durham

$306

Delta

Feb 26

RDU8:20 amRaleigh-Durham

11h 10m

1 stop

BOG7:30 pmBogotá El Dorado

Mar 22

BOG3:55 pmBogotá El Dorado

17h 19m

1 stop

RDU10:14 amRaleigh-Durham

$315

Delta

Mar 14

RDU5:20 pmRaleigh-Durham

22h 05m

1 stop

BOG2:25 pmBogotá El Dorado

Mar 21

BOG3:55 pmBogotá El Dorado

17h 19m

1 stop

RDU10:14 amRaleigh-Durham

$321

LATAM Airlines flights from Raleigh to South America

Our best LATAM Airlines deals on Raleigh to South America flight tickets

LATAM Airlines

Mar 16

RDU8:20 amRaleigh-Durham

9h 25m

1 stop

BOG4:45 pmBogotá El Dorado

Mar 22

BOG3:55 pmBogotá El Dorado

16h 11m

1 stop

RDU9:06 amRaleigh-Durham

$311

LATAM Airlines

Mar 20

RDU5:15 amRaleigh-Durham

10h 10m

1 stop

BOG2:25 pmBogotá El Dorado

Mar 27

BOG3:55 pmBogotá El Dorado

16h 11m

1 stop

RDU9:06 amRaleigh-Durham

$317

LATAM Airlines

Feb 23

RDU6:20 amRaleigh-Durham

8h 05m

1 stop

BOG2:25 pmBogotá El Dorado

Feb 26

BOG7:00 amBogotá El Dorado

17h 09m

2 stops

RDU12:09 amRaleigh-Durham

$320

Fly from

Fly to

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 4/16

6:58 pm-12:42 am

1 stop6h 44m

Medellín Jose Maria Cordova Intl

Sun 4/26

1:37 am-6:03 pm

1 stop15h 26m

$261

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 2/25

3:12 pm-10:55 pm

1 stop7h 43m

Bogotá El Dorado

Wed 3/4

6:10 am-1:23 pm

1 stop7h 13m

$263

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 2/23

6:06 am-1:30 pm

1 stop7h 24m

Cartagena Rafael Nunez

Thu 2/26

4:30 pm-11:59 pm

1 stop7h 29m

$271

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 5/16

8:13 pm-12:09 pm

2 stops16h 56m

Cartagena Rafael Nunez

Thu 5/21

1:25 pm-9:30 pm

1 stop7h 05m

$276

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Thu 3/12

12:45 pm-7:30 pm

1 stop7h 45m

Bogotá El Dorado

Wed 3/18

8:35 am-5:29 pm

1 stop7h 54m

$301

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Mon 3/2

6:20 am-9:35 pm

1 stop15h 15m

Quito Mariscal Sucr

Thu 3/12

7:05 am-7:56 pm

2 stops11h 51m

$386

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Mon 2/23

3:18 pm-5:02 am

2 stops13h 44m

Quito Mariscal Sucr

Sun 3/1

7:00 pm-2:13 pm

2 stops19h 13m

$406

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Thu 3/19

6:15 am-8:35 pm

1 stop15h 20m

Quito Mariscal Sucr

Mon 3/23

7:00 pm-7:56 pm

1 stop23h 56m

$407

RaleighSao Paulo

RDU - GRU

RDUGRU

Raleigh-Durham

Mon 3/23

10:30 am-10:20 am

1 stop22h 50m

Sao Paulo Guarulhos Intl

Thu 3/26

9:30 pm-9:34 am

1 stop13h 04m

$592

RaleighSao Paulo

RDU - GRU

RDUGRU

Raleigh-Durham

Mon 3/23

1:27 pm-7:15 am

1 stop16h 48m

Sao Paulo Guarulhos Intl

Thu 3/26

9:30 pm-11:44 pm

1 stop27h 14m

$594

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $580 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $509 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 8% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	7h 31m
Direct flights	None

The fastest flight from Raleigh to South America takes 7h 31m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of February 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $163	Free Cancellation	Rating 7.9 8,193 reviews	Search Delta flights
Spirit Airlines	PriceFrom $183	Free Cancellation	Rating 6.3 8,451 reviews	Search Spirit Airlines flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.5 1,559 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 9,283 reviews	Search United Airlines flights
JetBlue	PriceFrom $268	Free Cancellation	Rating 7.2 2,897 reviews	Search JetBlue flights
American Airlines	PriceFrom $283	Free Cancellation	Rating 7.2 11,278 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $288	Free Cancellation	Rating 7.5 1,920 reviews	Search LATAM Airlines flights
GOL	PriceFrom $447	Free Cancellation	Rating 7.3 1,172 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.