What airlines fly to South America?

American Airlines, Copa Airlines and Delta are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, American Airlines, and United Airlines are the most popular carriers operating from Raleigh-Durham to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of September 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$131 Cheap Flights from Raleigh to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:19 pm - 11:00 amRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

19h 41m1 stop Panama City Tocumen Intl

6:25 am - 2:28 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 03m1 stop Panama City Tocumen Intl

$320Copa Airlines

Mon, Oct 19 - Mon, Oct 26

4:21 pm - 2:15 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

22h 54m1 stop Panama City Tocumen Intl

4:30 pm - 2:28 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

20h 58m1 stop Panama City Tocumen Intl

$322Copa Airlines

Wed, Sep 30 - Sun, Oct 4

5:00 am - 3:36 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

10h 36m1 stop Miami

4:37 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 47m1 stop Miami

$335American Airlines

Wed, Nov 11 - Wed, Nov 18

6:20 am - 1:15 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

7h 55m1 stop Atlanta Hartsfield-Jackson

2:30 pm - 12:28 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

8h 58m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sat, Oct 24 - Thu, Oct 29

6:26 pm - 1:35 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

19h 09m2 stops Charlotte Douglas Miami

4:37 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 47m1 stop Miami

$340American Airlines

Fri, Nov 6 - Tue, Nov 10

6:20 am - 1:15 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

7h 55m1 stop Atlanta Hartsfield-Jackson

5:00 am - 7:53 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

13h 53m2 stops Bogotá El Dorado Miami

$343Delta

Sat, Oct 24 - Tue, Oct 27

6:00 am - 9:10 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 10m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

9:45 am - 10:48 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

24h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$346United Airlines

Mon, Sep 28 - Fri, Oct 9

6:00 am - 10:10 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 10m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

10:40 am - 1:43 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

27h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$346United Airlines

Sun, Jan 24 - Sun, Feb 7

8:10 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 00m1 stop Miami

10:45 am - 7:53 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

9h 08m1 stop Miami

$353LATAM Airlines

Sun, Oct 25 - Sat, Nov 7

8:10 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 00m1 stop Miami

10:45 am - 7:53 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

9h 08m1 stop Miami

$358LATAM Airlines

Fri, Oct 30 - Fri, Nov 6

Cheap last minute flights

Enter your travel dates to find the best prices.

6:25 am - 7:20 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 55m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:30 am - 9:59 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 29m1 stop Houston George Bush Intcntl

$427United Airlines

Sat, Sep 5 - Tue, Sep 22

6:30 am - 7:20 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 50m1 stop Houston George Bush Intcntl

8:30 am - 9:59 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 29m1 stop Houston George Bush Intcntl

$427United Airlines

Sat, Sep 5 - Tue, Sep 22

8:05 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 05m1 stop Miami

8:40 am - 7:46 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

10h 06m1 stop Miami

$445LATAM Airlines

Thu, Sep 3 - Thu, Sep 10

5:13 am - 1:05 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

8h 52m1 stop Miami

6:30 am - 7:45 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 15m1 stop Miami

$447American Airlines

Wed, Sep 2 - Wed, Sep 30

8:05 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 05m1 stop Miami

2:55 pm - 10:04 amBOG Bogotá El Dorado-RDU Raleigh-Durham

18h 09m1 stop Atlanta Hartsfield-Jackson

$455LATAM Airlines

Thu, Sep 3 - Thu, Sep 10

5:10 am - 7:15 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

15h 05m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 12:28 amBOG Bogotá El Dorado-RDU Raleigh-Durham

8h 33m1 stop Atlanta Hartsfield-Jackson

$459Delta

Wed, Sep 2 - Wed, Sep 9

5:10 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

16h 00m2 stops Atlanta Hartsfield-Jackson Miami

2:55 pm - 10:04 amBOG Bogotá El Dorado-RDU Raleigh-Durham

18h 09m1 stop Atlanta Hartsfield-Jackson

$460Delta

Thu, Sep 3 - Thu, Sep 10

10:37 am - 9:17 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

11h 40m2 stops Washington, D.C. Reagan-National Miami

2:10 pm - 11:57 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

8h 47m1 stop Miami

$484American Airlines

Wed, Sep 2 - Wed, Sep 9

11:23 am - 1:15 amRDU Raleigh-Durham-UIO Quito Mariscal Sucr

14h 52m2 stops New York John F Kennedy Intl Bogotá El Dorado

5:20 pm - 12:24 pmUIO Quito Mariscal Sucr-RDU Raleigh-Durham

19h 04m1 stop New York John F Kennedy Intl

$577Multiple Airlines

Thu, Sep 3 - Wed, Nov 4

5:42 pm - 5:40 pmRDU Raleigh-Durham-UIO Quito Mariscal Sucr

24h 58m2 stops New York John F Kennedy Intl Bogotá El Dorado

5:20 pm - 12:24 pmUIO Quito Mariscal Sucr-RDU Raleigh-Durham

19h 04m1 stop New York John F Kennedy Intl

$577Multiple Airlines

Thu, Sep 3 - Wed, Nov 4

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LATAM Airlines flights from Raleigh to South America

Our best LATAM Airlines deals on Raleigh to South America flight tickets

LATAM Airlines

Oct 25

RDU8:10 amRaleigh-Durham

13h 00m

1 stop

BOG8:10 pmBogotá El Dorado

Nov 7

BOG10:45 amBogotá El Dorado

9h 08m

1 stop

RDU7:53 pmRaleigh-Durham

$353

LATAM Airlines

Jan 21

RDU7:58 pmRaleigh-Durham

18h 12m

1 stop

CTG2:10 pmCartagena Rafael Nunez

Jan 28

CTG3:25 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:23 amRaleigh-Durham

$356

LATAM Airlines

Oct 30

RDU8:10 amRaleigh-Durham

13h 00m

1 stop

BOG8:10 pmBogotá El Dorado

Nov 6

BOG10:45 amBogotá El Dorado

9h 08m

1 stop

RDU7:53 pmRaleigh-Durham

$358

Copa Airlines flights from Raleigh to South America

Our best Copa Airlines deals on Raleigh to South America flight tickets

Copa Airlines

Oct 19

RDU4:19 pmRaleigh-Durham

19h 41m

1 stop

CTG11:00 amCartagena Rafael Nunez

Oct 26

CTG6:25 amCartagena Rafael Nunez

7h 03m

1 stop

RDU2:28 pmRaleigh-Durham

$320

Copa Airlines

Sep 30

RDU4:21 pmRaleigh-Durham

22h 54m

1 stop

MDE2:15 pmMedellín Jose Maria Cordova Intl

Oct 4

MDE4:30 pmMedellín Jose Maria Cordova Intl

20h 58m

1 stop

RDU2:28 pmRaleigh-Durham

$322

Copa Airlines

Sep 30

RDU4:21 pmRaleigh-Durham

23h 24m

1 stop

MDE2:45 pmMedellín Jose Maria Cordova Intl

Oct 4

MDE4:30 pmMedellín Jose Maria Cordova Intl

20h 58m

1 stop

RDU2:28 pmRaleigh-Durham

$323

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Mon 10/19

4:19 pm-11:00 am

1 stop19h 41m

Cartagena Rafael Nunez

Mon 10/26

6:25 am-2:28 pm

1 stop7h 03m

$320

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Wed 9/30

4:21 pm-2:15 pm

1 stop22h 54m

Medellín Jose Maria Cordova Intl

Sun 10/4

4:30 pm-2:28 pm

1 stop20h 58m

$322

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Wed 11/11

5:00 am-3:36 pm

1 stop10h 36m

Cartagena Rafael Nunez

Wed 11/18

4:37 pm-12:24 am

1 stop7h 47m

$335

Quickest round-trip

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 10/24

6:20 am-1:15 pm

1 stop7h 55m

Cartagena Rafael Nunez

Thu 10/29

2:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Fri 11/6

6:26 pm-1:35 pm

2 stops19h 09m

Cartagena Rafael Nunez

Tue 11/10

4:37 pm-12:24 am

1 stop7h 47m

$340

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 10/24

6:20 am-1:15 pm

1 stop7h 55m

Cartagena Rafael Nunez

Tue 10/27

5:00 am-7:53 pm

2 stops13h 53m

$343

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Mon 9/28

6:00 am-9:10 pm

2 stops16h 10m

Medellín Jose Maria Cordova Intl

Fri 10/9

9:45 am-10:48 am

2 stops24h 03m

$346

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Sun 1/24

6:00 am-10:10 pm

2 stops16h 10m

Medellín Jose Maria Cordova Intl

Sun 2/7

10:40 am-1:43 pm

2 stops27h 03m

$346

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Sun 10/25

8:10 am-8:10 pm

1 stop13h 00m

Bogotá El Dorado

Sat 11/7

10:45 am-7:53 pm

1 stop9h 08m

$353

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Fri 10/30

8:10 am-8:10 pm

1 stop13h 00m

Bogotá El Dorado

Fri 11/6

10:45 am-7:53 pm

1 stop9h 08m

$358

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $539. If you aren’t able to travel during the month of February, then book flights to South America from Raleigh during April instead. Flights to South America in April, while not as cheap as those in February, still average around $555.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $628 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $588 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 19% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Best Price Found	$131
Fastest flight time	6h 14m
Direct flights	None

The best one-way flight to South America from Raleigh in the past 72 hours is $131. The best round-trip flight deal from Raleigh to South America found on momondo in the last 72 hours is $320.

The fastest flight from Raleigh to South America takes 6h 14m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of September 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 3,034 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.6 1,550 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 10,151 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 12,027 reviews	Search American Airlines flights
Delta	PriceFrom $335	Free Cancellation	Rating 7.8 8,536 reviews	Search Delta flights
LATAM Airlines	PriceFrom $343	Free Cancellation	Rating 7.4 1,987 reviews	Search LATAM Airlines flights
GOL	PriceFrom $662	Free Cancellation	Rating 7.3 1,285 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.