What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, United Airlines, and American Airlines are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Copa Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of April 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$118 Cheap Flights from Raleigh to South America in 2026

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Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:19 pm - 8:15 am

RDU

MDE

16h 56m

1 stop

5:00 am - 2:29 pm

MDE

RDU

8h 29m

1 stop

$289Copa Airlines

Wed, May 6 - Mon, May 11

6:28 pm - 12:09 pm

RDU

CTG

18h 41m

2 stops

3:15 pm - 12:03 pm

CTG

RDU

19h 48m

2 stops

$294American Airlines

Sat, May 16 - Thu, May 21

5:05 am - 9:12 pm

RDU

GYE

17h 07m

2 stops

2:31 pm - 9:21 am

GYE

RDU

17h 50m

2 stops

$295American Airlines

Sat, May 9 - Mon, May 11

4:19 pm - 8:40 am

RDU

CTG

17h 21m

1 stop

6:20 am - 2:29 pm

CTG

RDU

7h 09m

1 stop

$298Copa Airlines

Sun, May 10 - Wed, May 13

4:21 pm - 8:39 am

RDU

CTG

17h 18m

1 stop

6:17 am - 2:28 pm

CTG

RDU

7h 11m

1 stop

$299Copa Airlines

Wed, Sep 2 - Mon, Sep 7

6:35 am - 1:13 pm

RDU

CTG

7h 38m

1 stop

2:30 pm - 12:27 am

CTG

RDU

8h 57m

1 stop

$311Delta

Tue, Sep 1 - Thu, Sep 10

6:15 am - 9:10 pm

RDU

MDE

15h 55m

1 stop

9:45 am - 10:07 am

MDE

RDU

23h 22m

2 stops

$312United Airlines

Mon, May 4 - Thu, May 14

7:55 pm - 12:58 pm

RDU

CTG

18h 03m

1 stop

2:30 pm - 8:51 am

CTG

RDU

17h 21m

1 stop

$315LATAM Airlines

Mon, May 18 - Sat, May 23

7:58 pm - 1:13 pm

RDU

CTG

18h 15m

1 stop

2:30 pm - 12:27 am

CTG

RDU

8h 57m

1 stop

$318LATAM Airlines

Mon, Aug 31 - Thu, Sep 10

8:04 am - 8:10 pm

RDU

BOG

13h 06m

1 stop

6:30 pm - 1:36 pm

BOG

RDU

18h 06m

2 stops

$365Delta

Tue, May 26 - Wed, Jun 3

GOL flights from Raleigh to South America

Our best GOL deals on Raleigh to South America flight tickets

GOL

Apr 26

RDU8:13 pmRaleigh-Durham

17h 35m

2 stops

MDE12:48 pmMedellín Jose Maria Cordova Intl

May 1

MDE1:50 pmMedellín Jose Maria Cordova Intl

17h 16m

2 stops

RDU8:06 amRaleigh-Durham

$457

GOL

Apr 26

RDU8:13 pmRaleigh-Durham

17h 35m

2 stops

MDE12:48 pmMedellín Jose Maria Cordova Intl

May 1

MDE1:50 pmMedellín Jose Maria Cordova Intl

17h 16m

2 stops

RDU8:06 amRaleigh-Durham

$461

GOL

May 4

RDU5:05 amRaleigh-Durham

9h 59m

2 stops

CTG2:04 pmCartagena Rafael Nunez

May 18

CTG1:25 pmCartagena Rafael Nunez

22h 32m

2 stops

RDU12:57 pmRaleigh-Durham

$483

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

May 2

RDU5:18 amRaleigh-Durham

9h 02m

1 stop

CTG1:20 pmCartagena Rafael Nunez

May 21

CTG2:13 pmCartagena Rafael Nunez

17h 38m

1 stop

RDU8:51 amRaleigh-Durham

$309

Delta

Sep 1

RDU6:35 amRaleigh-Durham

7h 38m

1 stop

CTG1:13 pmCartagena Rafael Nunez

Sep 10

CTG2:30 pmCartagena Rafael Nunez

8h 57m

1 stop

RDU12:27 amRaleigh-Durham

$311

Delta

May 2

RDU6:20 amRaleigh-Durham

8h 00m

1 stop

CTG1:20 pmCartagena Rafael Nunez

May 21

CTG8:24 amCartagena Rafael Nunez

11h 27m

2 stops

RDU8:51 pmRaleigh-Durham

$312

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 5/6

4:19 pm-8:15 am

1 stop16h 56m

Medellín Jose Maria Cordova Intl

Mon 5/11

5:00 am-2:29 pm

1 stop8h 29m

$289

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 5/16

6:28 pm-12:09 pm

2 stops18h 41m

Cartagena Rafael Nunez

Thu 5/21

3:15 pm-12:03 pm

2 stops19h 48m

$294

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sat 5/9

5:05 am-9:12 pm

2 stops17h 07m

Guayaquil Jose Joaquin de Olmedo

Mon 5/11

2:31 pm-9:21 am

2 stops17h 50m

$295

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sun 5/10

4:19 pm-8:40 am

1 stop17h 21m

Cartagena Rafael Nunez

Wed 5/13

6:20 am-2:29 pm

1 stop7h 09m

$298

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 9/2

4:21 pm-8:39 am

1 stop17h 18m

Cartagena Rafael Nunez

Mon 9/7

6:17 am-2:28 pm

1 stop7h 11m

$299

Quickest round-trip

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Tue 9/1

6:35 am-1:13 pm

1 stop7h 38m

Cartagena Rafael Nunez

Thu 9/10

2:30 pm-12:27 am

1 stop8h 57m

$311

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 5/4

6:15 am-9:10 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Thu 5/14

9:45 am-10:07 am

2 stops23h 22m

$312

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 5/18

7:55 pm-12:58 pm

1 stop18h 03m

Cartagena Rafael Nunez

Sat 5/23

2:30 pm-8:51 am

1 stop17h 21m

$315

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 8/31

7:58 pm-1:13 pm

1 stop18h 15m

Cartagena Rafael Nunez

Thu 9/10

2:30 pm-12:27 am

1 stop8h 57m

$318

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 5/26

8:04 am-8:10 pm

1 stop13h 06m

Bogotá El Dorado

Wed 6/3

6:30 pm-1:36 pm

2 stops18h 06m

$365

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $574 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $495 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 1% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	6h 05m
Direct flights	None

The fastest flight from Raleigh to South America takes 6h 05m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of April 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $102	Free Cancellation	Rating 7.9 8,458 reviews	Search Delta flights
LATAM Airlines	PriceFrom $143	Free Cancellation	Rating 7.4 1,911 reviews	Search LATAM Airlines flights
Spirit Airlines	PriceFrom $183	Free Cancellation	Rating 6.3 8,637 reviews	Search Spirit Airlines flights
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 2,954 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.5 1,578 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 9,650 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 11,672 reviews	Search American Airlines flights
GOL	PriceFrom $447	Free Cancellation	Rating 7.3 1,205 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.