What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, American Airlines, and Delta are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Copa Airlines and Delta are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of September 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$133 Cheap Flights from Raleigh to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:19 pm - 8:15 amRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 56m1 stop Panama City Tocumen Intl

5:00 am - 2:28 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

8h 28m1 stop Panama City Tocumen Intl

$319Copa Airlines

Mon, Oct 19 - Mon, Oct 26

4:19 pm - 11:00 amRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

19h 41m1 stop Panama City Tocumen Intl

6:25 am - 2:28 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 03m1 stop Panama City Tocumen Intl

$324Copa Airlines

Mon, Oct 19 - Mon, Oct 26

5:00 am - 1:35 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

8h 35m1 stop Miami

4:37 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 47m1 stop Miami

$335American Airlines

Mon, Nov 9 - Sat, Nov 14

6:20 am - 1:15 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

7h 55m1 stop Atlanta Hartsfield-Jackson

2:30 pm - 12:28 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

8h 58m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sat, Oct 17 - Sat, Oct 24

5:00 am - 3:36 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

10h 36m1 stop Miami

4:37 pm - 12:00 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

19h 23m2 stops Miami Charlotte Douglas

$340American Airlines

Wed, Nov 4 - Sat, Nov 7

7:00 am - 1:15 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

7h 15m1 stop Atlanta Hartsfield-Jackson

9:50 pm - 7:53 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

22h 03m2 stops Bogotá El Dorado Miami

$343LATAM Airlines

Sat, Oct 31 - Wed, Nov 4

8:10 am - 5:55 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

10h 45m1 stop Miami

10:45 am - 7:53 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

9h 08m1 stop Miami

$353LATAM Airlines

Sun, Oct 25 - Sat, Nov 7

6:40 am - 2:25 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

7h 45m1 stop New York John F Kennedy Intl

1:49 pm - 9:23 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 34m1 stop Fort Lauderdale

$361JetBlue

Sat, Nov 7 - Fri, Nov 13

6:30 am - 11:37 amRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

6h 07m1 stop Fort Lauderdale

12:44 pm - 9:23 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 39m1 stop Fort Lauderdale

$383JetBlue

Tue, Oct 20 - Fri, Oct 30

8:00 am - 7:30 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

12h 30m1 stop Atlanta Hartsfield-Jackson

9:00 am - 12:24 amBOG Bogotá El Dorado-RDU Raleigh-Durham

15h 24m1 stop Atlanta Hartsfield-Jackson

$385Delta

Sat, Oct 31 - Wed, Nov 11

Cheap last minute flights

Enter your travel dates to find the best prices.

5:44 pm - 12:48 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

20h 04m2 stops Charlotte Douglas Miami

1:53 pm - 10:10 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

19h 17m2 stops Miami Washington, D.C. Reagan-National

$408GOL

Fri, Sep 11 - Wed, Sep 16

6:30 am - 1:05 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

7h 35m1 stop Miami

6:30 am - 11:57 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

16h 27m1 stop Miami

$425American Airlines

Tue, Sep 8 - Thu, Sep 24

6:30 am - 1:05 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

7h 35m1 stop Miami

6:30 am - 11:57 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

16h 27m1 stop Miami

$427American Airlines

Tue, Sep 8 - Thu, Sep 24

4:21 pm - 12:06 amRDU Raleigh-Durham-BOG Bogotá El Dorado

8h 45m1 stop Panama City Tocumen Intl

6:10 am - 2:28 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

7h 18m1 stop Panama City Tocumen Intl

$443Copa Airlines

Fri, Sep 11 - Mon, Sep 28

4:21 pm - 12:06 amRDU Raleigh-Durham-BOG Bogotá El Dorado

8h 45m1 stop Panama City Tocumen Intl

4:59 am - 2:28 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

8h 29m1 stop Panama City Tocumen Intl

$447Copa Airlines

Mon, Sep 7 - Sun, Sep 27

8:00 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 10m1 stop Miami

11:00 am - 7:46 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

7h 46m1 stop Miami

$459Multiple Airlines

Tue, Sep 8 - Thu, Sep 24

5:15 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

15h 55m2 stops Atlanta Hartsfield-Jackson Miami

11:00 am - 12:28 amBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 28m2 stops Miami Atlanta Hartsfield-Jackson

$460Delta

Tue, Sep 8 - Thu, Sep 24

5:15 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

15h 55m2 stops Atlanta Hartsfield-Jackson Miami

11:00 am - 12:28 amBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 28m2 stops Miami Atlanta Hartsfield-Jackson

$464Delta

Tue, Sep 8 - Thu, Sep 24

8:00 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

13h 10m1 stop Miami

2:55 pm - 8:54 amBOG Bogotá El Dorado-RDU Raleigh-Durham

16h 59m1 stop Atlanta Hartsfield-Jackson

$475Multiple Airlines

Fri, Sep 11 - Wed, Sep 16

11:27 am - 8:15 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

9h 48m1 stop Miami

1:53 pm - 10:10 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

19h 17m2 stops Miami Washington, D.C. Reagan-National

$493GOL

Fri, Sep 11 - Wed, Sep 16

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Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

Oct 17

RDU6:20 amRaleigh-Durham

7h 55m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Oct 24

CTG2:30 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:28 amRaleigh-Durham

$339

Delta

Jan 16

RDU10:00 amRaleigh-Durham

28h 10m

1 stop

CTG2:10 pmCartagena Rafael Nunez

Jan 21

CTG3:25 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:23 amRaleigh-Durham

$356

Delta

Oct 24

RDU6:20 amRaleigh-Durham

7h 55m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Oct 29

CTG2:30 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:28 amRaleigh-Durham

$359

American Airlines flights from Raleigh to South America

Our best American Airlines deals on Raleigh to South America flight tickets

American Airlines

Nov 9

RDU5:00 amRaleigh-Durham

8h 35m

1 stop

CTG1:35 pmCartagena Rafael Nunez

Nov 14

CTG4:37 pmCartagena Rafael Nunez

7h 47m

1 stop

RDU12:24 amRaleigh-Durham

$335

American Airlines

Nov 4

RDU5:00 amRaleigh-Durham

10h 36m

1 stop

CTG3:36 pmCartagena Rafael Nunez

Nov 7

CTG4:37 pmCartagena Rafael Nunez

19h 23m

2 stops

RDU12:00 pmRaleigh-Durham

$340

American Airlines

Oct 16

RDU6:20 pmRaleigh-Durham

19h 15m

2 stops

CTG12:35 pmCartagena Rafael Nunez

Oct 23

CTG1:35 pmCartagena Rafael Nunez

19h 58m

2 stops

RDU10:33 amRaleigh-Durham

$341

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Mon 10/19

4:19 pm-8:15 am

1 stop16h 56m

Medellín Jose Maria Cordova Intl

Mon 10/26

5:00 am-2:28 pm

1 stop8h 28m

$319

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Mon 10/19

4:19 pm-11:00 am

1 stop19h 41m

Cartagena Rafael Nunez

Mon 10/26

6:25 am-2:28 pm

1 stop7h 03m

$324

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Mon 11/9

5:00 am-1:35 pm

1 stop8h 35m

Cartagena Rafael Nunez

Sat 11/14

4:37 pm-12:24 am

1 stop7h 47m

$335

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 10/17

6:20 am-1:15 pm

1 stop7h 55m

Cartagena Rafael Nunez

Sat 10/24

2:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Wed 11/4

5:00 am-3:36 pm

1 stop10h 36m

Cartagena Rafael Nunez

Sat 11/7

4:37 pm-12:00 pm

2 stops19h 23m

$340

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 10/31

7:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Wed 11/4

9:50 pm-7:53 pm

2 stops22h 03m

$343

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Sun 10/25

8:10 am-5:55 pm

1 stop10h 45m

Bogotá El Dorado

Sat 11/7

10:45 am-7:53 pm

1 stop9h 08m

$353

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 11/7

6:40 am-2:25 pm

1 stop7h 45m

Cartagena Rafael Nunez

Fri 11/13

1:49 pm-9:23 pm

1 stop7h 34m

$361

Quickest round-trip

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Tue 10/20

6:30 am-11:37 am

1 stop6h 07m

Cartagena Rafael Nunez

Fri 10/30

12:44 pm-9:23 pm

1 stop7h 39m

$383

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Sat 10/31

8:00 am-7:30 pm

1 stop12h 30m

Bogotá El Dorado

Wed 11/11

9:00 am-12:24 am

1 stop15h 24m

$385

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $542. If you aren’t able to travel during the month of February, then book flights to South America from Raleigh during September instead. Flights to South America in September, while not as cheap as those in February, still average around $545.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $636 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $590 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 19% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Best Price Found	$133
Fastest flight time	7h 10m
Direct flights	None

The best one-way flight to South America from Raleigh in the past 72 hours is $133. The best round-trip flight deal from Raleigh to South America found on momondo in the last 72 hours is $319.

The fastest flight from Raleigh to South America takes 7h 10m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of September 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 3,046 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.6 1,552 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 10,172 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 12,041 reviews	Search American Airlines flights
Delta	PriceFrom $337	Free Cancellation	Rating 7.8 8,558 reviews	Search Delta flights
LATAM Airlines	PriceFrom $344	Free Cancellation	Rating 7.4 1,988 reviews	Search LATAM Airlines flights
GOL	PriceFrom $651	Free Cancellation	Rating 7.3 1,291 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.