What airlines fly to South America?

American Airlines, Copa Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, Delta, and United Airlines are the most popular carriers operating from Raleigh-Durham to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of August 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$135 Cheap Flights from Raleigh to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:19 pm - 2:45 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

23h 26m1 stop Panama City Tocumen Intl

5:00 am - 2:28 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

8h 28m1 stop Panama City Tocumen Intl

$318Copa Airlines

Sun, Oct 18 - Mon, Oct 26

4:21 pm - 8:05 amRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

16h 44m1 stop Panama City Tocumen Intl

6:20 am - 2:28 pmCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 08m1 stop Panama City Tocumen Intl

$319Copa Airlines

Wed, Sep 30 - Mon, Oct 5

6:30 am - 10:15 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

15h 45m1 stop Houston George Bush Intcntl

10:45 am - 11:45 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

25h 00m1 stop Houston George Bush Intcntl

$332United Airlines

Tue, Feb 2 - Fri, Feb 12

11:35 am - 10:15 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

34h 40m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:45 am - 11:33 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

12h 48m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$332United Airlines

Thu, Feb 4 - Fri, Feb 12

6:00 am - 2:09 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

8h 09m1 stop Miami

3:10 pm - 11:59 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

8h 49m1 stop Miami

$333American Airlines

Wed, Feb 3 - Wed, Feb 10

5:00 am - 1:35 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

8h 35m1 stop Miami

4:37 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

7h 47m1 stop Miami

$335American Airlines

Sat, Nov 14 - Tue, Nov 17

7:25 am - 2:15 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

6h 50m1 stop Atlanta Hartsfield-Jackson

3:34 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

8h 50m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sat, Nov 7 - Sat, Nov 14

5:15 am - 2:19 pmRDU Raleigh-Durham-CTG Cartagena Rafael Nunez

9h 04m1 stop Atlanta Hartsfield-Jackson

3:34 pm - 12:24 amCTG Cartagena Rafael Nunez-RDU Raleigh-Durham

8h 50m1 stop Atlanta Hartsfield-Jackson

$339Delta

Mon, Nov 9 - Mon, Nov 16

8:10 am - 5:55 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

10h 45m1 stop Miami

10:45 am - 7:53 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

9h 08m1 stop Miami

$358LATAM Airlines

Sun, Oct 25 - Sat, Nov 7

8:10 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

12h 00m1 stop Miami

8:35 am - 8:56 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 21m1 stop Miami

$358LATAM Airlines

Fri, Nov 6 - Fri, Jan 22

Cheap last minute flights

Enter your travel dates to find the best prices.

6:30 am - 9:10 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

15h 40m1 stop Houston George Bush Intcntl

9:45 am - 9:34 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

22h 49m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$346United Airlines

Thu, Aug 27 - Fri, Sep 4

6:00 am - 9:10 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 10m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

9:45 am - 9:34 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

22h 49m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$346United Airlines

Thu, Aug 27 - Fri, Sep 4

4:22 pm - 8:15 amRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 53m1 stop Panama City Tocumen Intl

6:20 pm - 2:28 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

19h 08m1 stop Panama City Tocumen Intl

$442Copa Airlines

Fri, Aug 28 - Thu, Sep 3

4:22 pm - 9:29 amRDU Raleigh-Durham-BOG Bogotá El Dorado

18h 07m1 stop Panama City Tocumen Intl

6:17 pm - 2:28 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

19h 11m1 stop Panama City Tocumen Intl

$447Copa Airlines

Fri, Aug 28 - Sat, Sep 12

8:55 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

12h 15m2 stops Atlanta Hartsfield-Jackson Miami

8:40 am - 7:46 pmBOG Bogotá El Dorado-RDU Raleigh-Durham

10h 06m1 stop Miami

$462Delta

Fri, Aug 28 - Sat, Sep 12

4:22 pm - 8:15 amRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 53m1 stop Panama City Tocumen Intl

10:35 am - 7:20 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

31h 45m2 stops Panama City Tocumen Intl San Juan Luis Munoz Marin Intl

$478Multiple Airlines

Fri, Aug 28 - Wed, Sep 2

4:22 pm - 8:15 amRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

16h 53m1 stop Panama City Tocumen Intl

8:55 am - 12:42 amMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

14h 47m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$485Multiple Airlines

Fri, Aug 28 - Thu, Sep 3

11:26 am - 11:45 pmRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

13h 19m2 stops Orlando Bogotá El Dorado

11:15 pm - 6:02 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

17h 47m2 stops Bogotá El Dorado Orlando

$533LATAM Airlines

Fri, Aug 28 - Mon, Aug 31

8:05 am - 5:05 amRDU Raleigh-Durham-MDE Medellín Jose Maria Cordova Intl

22h 00m2 stops Miami Bogotá El Dorado

5:10 am - 6:02 pmMDE Medellín Jose Maria Cordova Intl-RDU Raleigh-Durham

11h 52m2 stops Bogotá El Dorado Orlando

$533LATAM Airlines

Thu, Aug 27 - Mon, Aug 31

8:55 am - 8:10 pmRDU Raleigh-Durham-BOG Bogotá El Dorado

12h 15m2 stops Atlanta Hartsfield-Jackson Miami

11:00 am - 12:28 amBOG Bogotá El Dorado-RDU Raleigh-Durham

12h 28m2 stops Miami Atlanta Hartsfield-Jackson

$576Delta

Fri, Aug 28 - Sat, Sep 12

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LATAM Airlines flights from Raleigh to South America

Our best LATAM Airlines deals on Raleigh to South America flight tickets

LATAM Airlines

Feb 4

RDU7:58 pmRaleigh-Durham

18h 12m

1 stop

CTG2:10 pmCartagena Rafael Nunez

Feb 18

CTG3:25 pmCartagena Rafael Nunez

17h 26m

1 stop

RDU8:51 amRaleigh-Durham

$356

LATAM Airlines

Oct 21

RDU8:10 amRaleigh-Durham

13h 00m

1 stop

BOG8:10 pmBogotá El Dorado

Oct 28

BOG10:45 amBogotá El Dorado

8h 08m

1 stop

RDU7:53 pmRaleigh-Durham

$358

LATAM Airlines

Oct 25

RDU8:10 amRaleigh-Durham

10h 45m

1 stop

BOG5:55 pmBogotá El Dorado

Nov 7

BOG10:45 amBogotá El Dorado

9h 08m

1 stop

RDU7:53 pmRaleigh-Durham

$366

Copa Airlines flights from Raleigh to South America

Our best Copa Airlines deals on Raleigh to South America flight tickets

Copa Airlines

Oct 18

RDU4:19 pmRaleigh-Durham

23h 26m

1 stop

MDE2:45 pmMedellín Jose Maria Cordova Intl

Oct 26

MDE5:00 amMedellín Jose Maria Cordova Intl

8h 28m

1 stop

RDU2:28 pmRaleigh-Durham

$318

Copa Airlines

Sep 30

RDU4:21 pmRaleigh-Durham

16h 44m

1 stop

CTG8:05 amCartagena Rafael Nunez

Oct 5

CTG6:20 amCartagena Rafael Nunez

7h 08m

1 stop

RDU2:28 pmRaleigh-Durham

$319

Copa Airlines

Oct 21

RDU4:19 pmRaleigh-Durham

26h 36m

1 stop

CTG5:55 pmCartagena Rafael Nunez

Oct 26

CTG6:25 amCartagena Rafael Nunez

7h 03m

1 stop

RDU2:28 pmRaleigh-Durham

$324

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Sun 10/18

4:19 pm-2:45 pm

1 stop23h 26m

Medellín Jose Maria Cordova Intl

Mon 10/26

5:00 am-2:28 pm

1 stop8h 28m

$318

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Wed 9/30

4:21 pm-8:05 am

1 stop16h 44m

Cartagena Rafael Nunez

Mon 10/5

6:20 am-2:28 pm

1 stop7h 08m

$319

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Tue 2/2

6:30 am-10:15 pm

1 stop15h 45m

Medellín Jose Maria Cordova Intl

Fri 2/12

10:45 am-11:45 am

1 stop25h 00m

$332

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Thu 2/4

11:35 am-10:15 pm

2 stops34h 40m

Medellín Jose Maria Cordova Intl

Fri 2/12

10:45 am-11:33 pm

2 stops12h 48m

$332

RaleighMedellín

RDU Raleigh-Durham - MDE Medellín Jose Maria Cordova Intl

RDUMDE

Raleigh-Durham

Wed 2/3

6:00 am-2:09 pm

1 stop8h 09m

Medellín Jose Maria Cordova Intl

Wed 2/10

3:10 pm-11:59 pm

1 stop8h 49m

$333

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 11/14

5:00 am-1:35 pm

1 stop8h 35m

Cartagena Rafael Nunez

Tue 11/17

4:37 pm-12:24 am

1 stop7h 47m

$335

Quickest round-trip

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Sat 11/7

7:25 am-2:15 pm

1 stop6h 50m

Cartagena Rafael Nunez

Sat 11/14

3:34 pm-12:24 am

1 stop8h 50m

$339

RaleighCartagena

RDU Raleigh-Durham - CTG Cartagena Rafael Nunez

RDUCTG

Raleigh-Durham

Mon 11/9

5:15 am-2:19 pm

1 stop9h 04m

Cartagena Rafael Nunez

Mon 11/16

3:34 pm-12:24 am

1 stop8h 50m

$339

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Sun 10/25

8:10 am-5:55 pm

1 stop10h 45m

Bogotá El Dorado

Sat 11/7

10:45 am-7:53 pm

1 stop9h 08m

$358

RaleighBogotá

RDU Raleigh-Durham - BOG Bogotá El Dorado

RDUBOG

Raleigh-Durham

Fri 11/6

8:10 am-8:10 pm

1 stop12h 00m

Bogotá El Dorado

Fri 1/22

8:35 am-8:56 pm

1 stop12h 21m

$358

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $542. If you aren’t able to travel during the month of February, then book flights to South America from Raleigh during April instead. Flights to South America in April, while not as cheap as those in February, still average around $555.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $624 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $539 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Best Price Found	$135
Fastest flight time	6h 19m
Direct flights	None

The best one-way flight to South America from Raleigh in the past 72 hours is $135. The best round-trip flight deal from Raleigh to South America found on momondo in the last 72 hours is $318.

The fastest flight from Raleigh to South America takes 6h 19m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of August 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 3,036 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.6 1,552 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 10,124 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 11,995 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $335	Free Cancellation	Rating 7.4 1,988 reviews	Search LATAM Airlines flights
Delta	PriceFrom $337	Free Cancellation	Rating 7.8 8,529 reviews	Search Delta flights
GOL	PriceFrom $662	Free Cancellation	Rating 7.3 1,282 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.