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Cheap flights from Raleigh to South America from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to South America departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Raleigh to South America

Cheap round-trip flights

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Copa Airlines Logo
3:11 pm - 8:18 amRDU-MDE
17h 07m1 stop
Copa Airlines Logo
6:24 am - 1:25 pmMDE-RDU
7h 01m1 stop
$253Copa Airlines
Find Deal
Mon, Dec 8 - Wed, Dec 10
Spirit Airlines Logo
5:50 pm - 1:09 amRDU-MDE
7h 19m1 stop
Spirit Airlines Logo
2:05 am - 4:55 pmMDE-RDU
14h 50m1 stop
$264Spirit Airlines
Find Deal
Mon, Dec 8 - Wed, Dec 10
American Airlines Logo
7:21 pm - 1:30 pmRDU-CTG
18h 09m2 stops
American Airlines Logo
4:30 pm - 10:03 amCTG-RDU
17h 33m2 stops
$291American Airlines
Find Deal
Mon, Dec 8 - Wed, Dec 10
American Airlines Logo
7:54 pm - 1:30 pmRDU-CTG
17h 36m1 stop
American Airlines Logo
4:30 pm - 11:59 pmCTG-RDU
7h 29m1 stop
$293American Airlines
Find Deal
Mon, Jan 19 - Wed, Jan 21
United Airlines Logo
6:07 am - 10:05 pmRDU-MDE
15h 58m1 stop
United Airlines Logo
10:45 am - 2:07 pmMDE-RDU
27h 22m2 stops
$294United Airlines
Find Deal
Tue, Nov 18 - Tue, Dec 9
United Airlines Logo
6:15 am - 10:05 pmRDU-MDE
15h 50m1 stop
United Airlines Logo
10:45 am - 10:30 pmMDE-RDU
11h 45m1 stop
$303United Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9
LATAM Airlines Logo
11:05 am - 7:30 pmRDU-BOG
8h 25m1 stop
LATAM Airlines Logo
7:00 am - 8:27 pmBOG-RDU
13h 27m1 stop
$336LATAM Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
LATAM Airlines Logo
7:15 am - 2:25 pmRDU-BOG
7h 10m1 stop
LATAM Airlines Logo
3:55 pm - 12:20 amBOG-RDU
8h 25m1 stop
$341LATAM Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Delta Logo
6:18 am - 2:15 pmRDU-CTG
7h 57m1 stop
Delta Logo
3:30 pm - 3:45 pmCTG-RDU
24h 15m1 stop
$343Delta
Find Deal
Mon, Feb 16 - Fri, Feb 20
Delta Logo
8:08 am - 4:45 pmRDU-BOG
8h 37m1 stop
Delta Logo
3:55 pm - 9:50 amBOG-RDU
16h 55m1 stop
$343Delta
Find Deal
Fri, Feb 27 - Mon, Mar 23

LATAM Airlines flights from Raleigh to South America

Our best LATAM Airlines deals on Raleigh to South America flight tickets
LATAM Airlines
Nov 14
RDU11:05 amRaleigh-Durham
8h 25m
1 stop
BOG7:30 pmBogotá El Dorado
Nov 17
BOG7:00 amBogotá El Dorado
13h 27m
1 stop
RDU8:27 pmRaleigh-Durham
$336
Find similar
LATAM Airlines
Nov 14
RDU7:15 amRaleigh-Durham
7h 10m
1 stop
BOG2:25 pmBogotá El Dorado
Nov 17
BOG3:55 pmBogotá El Dorado
8h 25m
1 stop
RDU12:20 amRaleigh-Durham
$341
Find similar
LATAM Airlines
Nov 6
RDU12:35 pmRaleigh-Durham
6h 55m
1 stop
BOG7:30 pmBogotá El Dorado
Nov 10
BOG3:55 pmBogotá El Dorado
8h 25m
1 stop
RDU12:20 amRaleigh-Durham
$367
Find similar

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets
Delta
Feb 27
RDU8:08 amRaleigh-Durham
8h 37m
1 stop
BOG4:45 pmBogotá El Dorado
Mar 23
BOG3:55 pmBogotá El Dorado
16h 55m
1 stop
RDU9:50 amRaleigh-Durham
$343
Find similar
Delta
Feb 28
RDU6:59 pmRaleigh-Durham
21h 46m
2 stops
BOG4:45 pmBogotá El Dorado
Mar 24
BOG7:00 amBogotá El Dorado
13h 58m
2 stops
RDU9:58 pmRaleigh-Durham
$348
Find similar
Delta
Feb 28
RDU5:55 pmRaleigh-Durham
20h 40m
1 stop
BOG2:35 pmBogotá El Dorado
Mar 28
BOG3:55 pmBogotá El Dorado
16h 55m
1 stop
RDU9:50 amRaleigh-Durham
$349
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Raleigh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Raleigh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 12/8

3:11 pm-8:18 am

1 stop17h 07m

Medellín Jose Maria Cordova Intl

Wed 12/10

6:24 am-1:25 pm

1 stop7h 01m

$253

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 12/8

5:50 pm-1:09 am

1 stop7h 19m

Medellín Jose Maria Cordova Intl

Wed 12/10

2:05 am-4:55 pm

1 stop14h 50m

$264

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 12/8

7:21 pm-1:30 pm

2 stops18h 09m

Cartagena Rafael Nunez

Wed 12/10

4:30 pm-10:03 am

2 stops17h 33m

$291

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 1/19

7:54 pm-1:30 pm

1 stop17h 36m

Cartagena Rafael Nunez

Wed 1/21

4:30 pm-11:59 pm

1 stop7h 29m

$293

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Tue 11/18

6:07 am-10:05 pm

1 stop15h 58m

Medellín Jose Maria Cordova Intl

Tue 12/9

10:45 am-2:07 pm

2 stops27h 22m

$294

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 2/5

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Mon 2/9

10:45 am-10:30 pm

1 stop11h 45m

$303

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 11/14

11:05 am-7:30 pm

1 stop8h 25m

Bogotá El Dorado

Mon 11/17

7:00 am-8:27 pm

1 stop13h 27m

$336

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 11/14

7:15 am-2:25 pm

1 stop7h 10m

Bogotá El Dorado

Mon 11/17

3:55 pm-12:20 am

1 stop8h 25m

$341

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 2/16

6:18 am-2:15 pm

1 stop7h 57m

Cartagena Rafael Nunez

Fri 2/20

3:30 pm-3:45 pm

1 stop24h 15m

$343

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 2/27

8:08 am-4:45 pm

1 stop8h 37m

Bogotá El Dorado

Mon 3/23

3:55 pm-9:50 am

1 stop16h 55m

$343

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Raleigh to South America is on a Monday when prices can be found for as low as $594. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to South America for around $711.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Raleigh to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $521. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $742 on average. Flights to South America from Raleigh at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $545 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Direct flights

None
There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.
Search flight deals

  • When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

    Prices for flights from Raleigh-Durham Airport to South America refresh daily.

  • How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

  • How old do you have to be to fly from Raleigh-Durham Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $245Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
Spirit AirlinesPriceFrom $272Free CancellationRating
6.3
8,113 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $282Free CancellationRating
7.5
1,874 reviews
Search LATAM Airlines flights
DeltaPriceFrom $282Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $283Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $314Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights
JetBluePriceFrom $374Free CancellationRating
7.2
2,908 reviews
Search JetBlue flights
GOLPriceFrom $540Free CancellationRating
7.3
1,123 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $273
Flights to Buenos Airesfrom $466
Flights to Bogotáfrom $182
Flights to Sao Paulofrom $381
Flights to Rio de Janeirofrom $424
Flights to Medellínfrom $166
Flights to Santiagofrom $380
Flights to Cartagenafrom $183
Flights to Quitofrom $315
Flights to Cuscofrom $367
Flights to Guayaquilfrom $233
Flights to Califrom $187