What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, American Airlines, and United Airlines are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Delta and Copa Airlines are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of January 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$115 Cheap Flights from Raleigh to South America in 2026

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Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:14 pm - 8:18 am

RDU

MDE

17h 04m

1 stop

6:25 am - 2:23 pm

MDE

RDU

6h 58m

1 stop

$252Copa Airlines

Fri, Mar 20 - Mon, Mar 23

3:12 pm - 8:41 am

RDU

CTG

17h 29m

1 stop

6:25 am - 1:14 pm

CTG

RDU

6h 49m

1 stop

$259Copa Airlines

Fri, Feb 6 - Wed, Feb 11

11:51 am - 9:10 pm

RDU

MDE

9h 19m

1 stop

7:00 am - 11:44 pm

MDE

RDU

16h 44m

2 stops

$289American Airlines

Mon, Feb 2 - Fri, Feb 6

7:27 pm - 1:30 pm

RDU

CTG

18h 03m

2 stops

4:30 pm - 11:59 pm

CTG

RDU

7h 29m

1 stop

$294American Airlines

Sat, Feb 7 - Tue, Feb 10

6:15 am - 10:05 pm

RDU

MDE

15h 50m

1 stop

10:45 am - 10:38 pm

MDE

RDU

11h 53m

1 stop

$304United Airlines

Mon, Feb 2 - Thu, Feb 5

6:18 am - 10:35 pm

RDU

BOG

16h 17m

1 stop

8:15 am - 10:37 pm

BOG

RDU

13h 22m

1 stop

$304United Airlines

Sun, Feb 22 - Fri, Mar 13

5:54 pm - 5:17 am

RDU

UIO

11h 23m

2 stops

6:45 pm - 7:56 pm

UIO

RDU

24h 11m

2 stops

$379LATAM Airlines

Mon, Mar 2 - Thu, Mar 12

6:25 am - 9:35 pm

RDU

UIO

15h 10m

1 stop

6:45 pm - 8:34 pm

UIO

RDU

25h 49m

2 stops

$391LATAM Airlines

Wed, Jan 28 - Mon, Feb 2

8:15 am - 10:00 pm

RDU

LIM

14h 45m

1 stop

8:55 am - 12:18 am

LIM

RDU

14h 23m

2 stops

$444Delta

Thu, Apr 23 - Sun, Apr 26

3:45 pm - 9:15 am

RDU

GIG

16h 30m

1 stop

7:35 pm - 12:18 pm

GIG

RDU

17h 43m

2 stops

$529Delta

Tue, Mar 17 - Fri, Mar 20

American Airlines flights from Raleigh to South America

Our best American Airlines deals on Raleigh to South America flight tickets

American Airlines

Apr 11

RDU5:05 amRaleigh-Durham

16h 10m

2 stops

MDE8:15 pmMedellín Jose Maria Cordova Intl

Apr 16

MDE1:53 pmMedellín Jose Maria Cordova Intl

17h 13m

2 stops

RDU8:06 amRaleigh-Durham

$289

American Airlines

Feb 7

RDU7:27 pmRaleigh-Durham

18h 03m

2 stops

CTG1:30 pmCartagena Rafael Nunez

Feb 10

CTG4:30 pmCartagena Rafael Nunez

7h 29m

1 stop

RDU11:59 pmRaleigh-Durham

$294

American Airlines

Feb 27

RDU8:19 pmRaleigh-Durham

19h 11m

2 stops

CTG3:30 pmCartagena Rafael Nunez

Mar 6

CTG2:30 pmCartagena Rafael Nunez

20h 03m

2 stops

RDU10:33 amRaleigh-Durham

$295

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

Jan 29

RDU11:00 amRaleigh-Durham

16h 15m

2 stops

BOG3:15 amBogotá El Dorado

Mar 29

BOG3:55 pmBogotá El Dorado

16h 11m

1 stop

RDU9:06 amRaleigh-Durham

$354

Delta

Feb 18

RDU5:54 pmRaleigh-Durham

22h 51m

2 stops

BOG4:45 pmBogotá El Dorado

Mar 4

BOG10:55 amBogotá El Dorado

13h 14m

2 stops

RDU12:09 amRaleigh-Durham

$359

Delta

Feb 26

RDU6:20 amRaleigh-Durham

8h 05m

1 stop

BOG2:25 pmBogotá El Dorado

Mar 21

BOG3:55 pmBogotá El Dorado

16h 11m

1 stop

RDU9:06 amRaleigh-Durham

$364

Fly from

Fly to

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 3/20

4:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Mon 3/23

6:25 am-2:23 pm

1 stop6h 58m

$252

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 2/6

3:12 pm-8:41 am

1 stop17h 29m

Cartagena Rafael Nunez

Wed 2/11

6:25 am-1:14 pm

1 stop6h 49m

$259

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 2/2

11:51 am-9:10 pm

1 stop9h 19m

Medellín Jose Maria Cordova Intl

Fri 2/6

7:00 am-11:44 pm

2 stops16h 44m

$289

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 2/7

7:27 pm-1:30 pm

2 stops18h 03m

Cartagena Rafael Nunez

Tue 2/10

4:30 pm-11:59 pm

1 stop7h 29m

$294

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 2/2

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Thu 2/5

10:45 am-10:38 pm

1 stop11h 53m

$304

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sun 2/22

6:18 am-10:35 pm

1 stop16h 17m

Bogotá El Dorado

Fri 3/13

8:15 am-10:37 pm

1 stop13h 22m

$304

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Mon 3/2

5:54 pm-5:17 am

2 stops11h 23m

Quito Mariscal Sucr

Thu 3/12

6:45 pm-7:56 pm

2 stops24h 11m

$379

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Wed 1/28

6:25 am-9:35 pm

1 stop15h 10m

Quito Mariscal Sucr

Mon 2/2

6:45 pm-8:34 pm

2 stops25h 49m

$391

RaleighLima

RDU - LIM

RDULIM

Raleigh-Durham

Thu 4/23

8:15 am-10:00 pm

1 stop14h 45m

Lima J Chavez Intl

Sun 4/26

8:55 am-12:18 am

2 stops14h 23m

$444

RaleighRio de Janeiro

RDU - GIG

RDUGIG

Raleigh-Durham

Tue 3/17

3:45 pm-9:15 am

1 stop16h 30m

Rio de Janeiro–Galeão Intl

Fri 3/20

7:35 pm-12:18 pm

2 stops17h 43m

$529

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $595 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $554 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	7h 26m
Direct flights	None

The fastest flight from Raleigh to South America takes 7h 26m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of January 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $161	Free Cancellation	Rating 7.9 8,049 reviews	Search Delta flights
Spirit Airlines	PriceFrom $183	Free Cancellation	Rating 6.3 8,320 reviews	Search Spirit Airlines flights
LATAM Airlines	PriceFrom $225	Free Cancellation	Rating 7.5 1,904 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $245	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 9,164 reviews	Search United Airlines flights
American Airlines	PriceFrom $283	Free Cancellation	Rating 7.2 11,132 reviews	Search American Airlines flights
JetBlue	PriceFrom $297	Free Cancellation	Rating 7.2 2,887 reviews	Search JetBlue flights
GOL	PriceFrom $447	Free Cancellation	Rating 7.3 1,151 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.