What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, United Airlines, and Delta are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Copa Airlines and Delta are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of July 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$125 Cheap Flights from Raleigh to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:21 pm - 8:40 am

RDU

CTG

17h 19m

1 stop

6:20 am - 2:28 pm

CTG

RDU

7h 08m

1 stop

$297Copa Airlines

Mon, Sep 14 - Mon, Sep 21

4:21 pm - 8:40 am

RDU

CTG

17h 19m

1 stop

6:20 am - 2:28 pm

CTG

RDU

7h 08m

1 stop

$297Copa Airlines

Wed, Sep 23 - Wed, Sep 30

5:00 pm - 9:10 pm

RDU

MDE

29h 10m

2 stops

9:45 am - 9:34 am

MDE

RDU

22h 49m

2 stops

$326United Airlines

Mon, Sep 21 - Thu, Sep 24

1:00 pm - 10:10 pm

RDU

MDE

9h 10m

1 stop

10:40 am - 10:44 am

MDE

RDU

24h 04m

2 stops

$326United Airlines

Wed, Nov 4 - Wed, Nov 11

7:25 am - 1:15 pm

RDU

CTG

6h 50m

1 stop

3:30 pm - 12:28 am

CTG

RDU

8h 58m

1 stop

$339LATAM Airlines

Thu, Oct 29 - Thu, Nov 5

7:25 am - 1:15 pm

RDU

CTG

6h 50m

1 stop

2:30 pm - 8:52 am

CTG

RDU

17h 22m

1 stop

$339LATAM Airlines

Sat, Oct 17 - Sat, Oct 24

6:20 am - 1:15 pm

RDU

CTG

7h 55m

1 stop

3:30 pm - 12:28 am

CTG

RDU

8h 58m

1 stop

$339Delta

Thu, Oct 29 - Sat, Nov 7

5:15 am - 1:05 pm

RDU

CTG

8h 50m

1 stop

2:30 pm - 12:28 am

CTG

RDU

8h 58m

1 stop

$339Delta

Sat, Sep 12 - Sat, Sep 19

5:30 pm - 12:35 pm

RDU

CTG

20h 05m

2 stops

1:35 pm - 10:02 am

CTG

RDU

19h 27m

2 stops

$358American Airlines

Sat, Sep 12 - Sat, Sep 19

5:30 pm - 12:35 pm

RDU

CTG

20h 05m

2 stops

1:35 pm - 10:14 pm

CTG

RDU

7h 39m

1 stop

$358American Airlines

Sat, Sep 19 - Fri, Sep 25

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American Airlines flights from Raleigh to South America

Our best American Airlines deals on Raleigh to South America flight tickets

American Airlines

Sep 19

RDU6:23 pmRaleigh-Durham

19h 12m

2 stops

CTG12:35 pmCartagena Rafael Nunez

Sep 25

CTG1:35 pmCartagena Rafael Nunez

19h 27m

2 stops

RDU10:02 amRaleigh-Durham

$358

American Airlines

Sep 12

RDU4:50 pmRaleigh-Durham

20h 45m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Sep 19

CTG1:35 pmCartagena Rafael Nunez

19h 27m

2 stops

RDU10:02 amRaleigh-Durham

$361

American Airlines

Sep 9

RDU6:20 amRaleigh-Durham

7h 45m

1 stop

BOG1:05 pmBogotá El Dorado

Sep 16

BOG2:10 pmBogotá El Dorado

8h 47m

1 stop

RDU11:57 pmRaleigh-Durham

$362

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

Oct 29

RDU6:20 amRaleigh-Durham

7h 55m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Nov 7

CTG3:30 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:28 amRaleigh-Durham

$339

Delta

Oct 29

RDU5:15 amRaleigh-Durham

9h 00m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Nov 4

CTG4:00 amCartagena Rafael Nunez

15h 53m

2 stops

RDU7:53 pmRaleigh-Durham

$343

Delta

Oct 28

RDU6:13 pmRaleigh-Durham

20h 02m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Nov 7

CTG3:30 pmCartagena Rafael Nunez

8h 58m

1 stop

RDU12:28 amRaleigh-Durham

$346

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 9/14

4:21 pm-8:40 am

1 stop17h 19m

Cartagena Rafael Nunez

Mon 9/21

6:20 am-2:28 pm

1 stop7h 08m

$297

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 9/23

4:21 pm-8:40 am

1 stop17h 19m

Cartagena Rafael Nunez

Wed 9/30

6:20 am-2:28 pm

1 stop7h 08m

$297

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 9/21

5:00 pm-9:10 pm

2 stops29h 10m

Medellín Jose Maria Cordova Intl

Thu 9/24

9:45 am-9:34 am

2 stops22h 49m

$326

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 11/4

1:00 pm-10:10 pm

1 stop9h 10m

Medellín Jose Maria Cordova Intl

Wed 11/11

10:40 am-10:44 am

2 stops24h 04m

$326

Quickest round-trip

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 10/29

7:25 am-1:15 pm

1 stop6h 50m

Cartagena Rafael Nunez

Thu 11/5

3:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 10/17

7:25 am-1:15 pm

1 stop6h 50m

Cartagena Rafael Nunez

Sat 10/24

2:30 pm-8:52 am

1 stop17h 22m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 10/29

6:20 am-1:15 pm

1 stop7h 55m

Cartagena Rafael Nunez

Sat 11/7

3:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 9/12

5:15 am-1:05 pm

1 stop8h 50m

Cartagena Rafael Nunez

Sat 9/19

2:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 9/12

5:30 pm-12:35 pm

2 stops20h 05m

Cartagena Rafael Nunez

Sat 9/19

1:35 pm-10:02 am

2 stops19h 27m

$358

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 9/19

5:30 pm-12:35 pm

2 stops20h 05m

Cartagena Rafael Nunez

Fri 9/25

1:35 pm-10:14 pm

1 stop7h 39m

$358

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $460. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during October instead. Flights to South America in October, while not as cheap as those in September, still average around $534.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $611 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $539 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	6h 01m
Direct flights	None

The fastest flight from Raleigh to South America takes 6h 01m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of July 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $102	Free Cancellation	Rating 7.8 8,489 reviews	Search Delta flights
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 3,030 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.6 1,558 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 10,046 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 11,841 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $335	Free Cancellation	Rating 7.4 1,968 reviews	Search LATAM Airlines flights
GOL	PriceFrom $662	Free Cancellation	Rating 7.3 1,264 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.