What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, American Airlines, and United Airlines are the most popular carriers operating from Raleigh-Durham to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of December 2025.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$102 Cheap Flights from Raleigh to South America in 2025/26

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Cheap round-trip flights

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3:09 pm - 8:18 am

RDU

MDE

17h 09m1 stop

5:00 am - 1:14 pm

MDE

RDU

8h 14m1 stop

$253Copa Airlines

Wed, Jan 28 - Wed, Feb 4

3:14 pm - 8:06 am

RDU

CTG

16h 52m1 stop

6:25 am - 2:23 pm

CTG

RDU

6h 58m1 stop

$256Copa Airlines

Wed, Mar 4 - Mon, Mar 9

7:54 pm - 3:30 pm

RDU

CTG

19h 36m1 stop

4:30 pm - 11:01 am

CTG

RDU

18h 31m1 stop

$285American Airlines

Thu, Jan 29 - Thu, Feb 5

7:35 pm - 1:30 pm

RDU

CTG

17h 55m2 stops

4:30 pm - 11:01 am

CTG

RDU

18h 31m1 stop

$290American Airlines

Thu, Jan 29 - Thu, Feb 5

6:15 am - 10:35 pm

RDU

BOG

16h 20m2 stops

8:15 am - 2:06 pm

BOG

RDU

29h 51m2 stops

$294United Airlines

Sat, Jan 24 - Tue, Jan 27

6:15 am - 10:05 pm

RDU

MDE

15h 50m1 stop

10:45 am - 10:30 pm

MDE

RDU

11h 45m1 stop

$303United Airlines

Mon, Feb 2 - Fri, Feb 6

6:25 pm - 5:17 am

RDU

UIO

11h 52m2 stops

7:05 am - 8:57 pm

UIO

RDU

12h 52m2 stops

$400LATAM Airlines

Tue, Mar 10 - Sat, Mar 14

6:25 pm - 4:58 am

RDU

UIO

11h 33m2 stops

7:06 am - 9:00 pm

UIO

RDU

12h 54m2 stops

$413LATAM Airlines

Wed, Apr 1 - Wed, Apr 22

5:20 am - 6:59 pm

RDU

UIO

14h 39m1 stop

12:59 am - 12:51 pm

UIO

RDU

10h 52m1 stop

$421Delta

Mon, Apr 20 - Wed, Apr 29

6:25 pm - 4:58 am

RDU

UIO

11h 33m2 stops

7:00 pm - 12:51 pm

UIO

RDU

16h 51m2 stops

$425Delta

Mon, Mar 30 - Wed, Apr 15

Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Delta

Jan 28

RDU12:12 pmRaleigh-Durham

15h 03m

2 stops

BOG3:15 amBogotá El Dorado

Feb 1

BOG10:55 amBogotá El Dorado

9h 39m

1 stop

RDU8:34 pmRaleigh-Durham

$343

Find similar

Delta

Mar 10

RDU8:20 amRaleigh-Durham

12h 41m

2 stops

CTG8:01 pmCartagena Rafael Nunez

Mar 14

CTG4:35 amCartagena Rafael Nunez

15h 22m

2 stops

RDU8:57 pmRaleigh-Durham

$345

Find similar

Delta

Feb 4

RDU4:49 pmRaleigh-Durham

19h 16m

2 stops

BOG12:05 pmBogotá El Dorado

Feb 13

BOG7:00 amBogotá El Dorado

15h 34m

2 stops

RDU10:34 pmRaleigh-Durham

$348

Find similar

Copa Airlines flights from Raleigh to South America

Our best Copa Airlines deals on Raleigh to South America flight tickets

Copa Airlines

Jan 28

RDU3:09 pmRaleigh-Durham

17h 09m

1 stop

MDE8:18 amMedellín Jose Maria Cordova Intl

Feb 4

MDE5:00 amMedellín Jose Maria Cordova Intl

8h 14m

1 stop

RDU1:14 pmRaleigh-Durham

$253

Find similar

Copa Airlines

Mar 4

RDU3:14 pmRaleigh-Durham

16h 52m

1 stop

CTG8:06 amCartagena Rafael Nunez

Mar 9

CTG6:25 amCartagena Rafael Nunez

6h 58m

1 stop

RDU2:23 pmRaleigh-Durham

$256

Find similar

Copa Airlines

Jan 19

RDU3:09 pmRaleigh-Durham

7h 51m

1 stop

CTG11:00 pmCartagena Rafael Nunez

Jan 24

CTG12:03 pmCartagena Rafael Nunez

25h 12m

1 stop

RDU1:15 pmRaleigh-Durham

$265

Find similar

Fly from

Fly to

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 1/28

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

Wed 2/4

5:00 am-1:14 pm

1 stop8h 14m

$253

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 3/4

3:14 pm-8:06 am

1 stop16h 52m

Cartagena Rafael Nunez

Mon 3/9

6:25 am-2:23 pm

1 stop6h 58m

$256

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 1/29

7:54 pm-3:30 pm

1 stop19h 36m

Cartagena Rafael Nunez

Thu 2/5

4:30 pm-11:01 am

1 stop18h 31m

$285

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 1/29

7:35 pm-1:30 pm

2 stops17h 55m

Cartagena Rafael Nunez

Thu 2/5

4:30 pm-11:01 am

1 stop18h 31m

$290

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sat 1/24

6:15 am-10:35 pm

2 stops16h 20m

Bogotá El Dorado

Tue 1/27

8:15 am-2:06 pm

2 stops29h 51m

$294

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 2/2

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-10:30 pm

1 stop11h 45m

$303

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Tue 3/10

6:25 pm-5:17 am

2 stops11h 52m

Quito Mariscal Sucr

Sat 3/14

7:05 am-8:57 pm

2 stops12h 52m

$400

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Wed 4/1

6:25 pm-4:58 am

2 stops11h 33m

Quito Mariscal Sucr

Wed 4/22

7:06 am-9:00 pm

2 stops12h 54m

$413

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Mon 4/20

5:20 am-6:59 pm

1 stop14h 39m

Quito Mariscal Sucr

Wed 4/29

12:59 am-12:51 pm

1 stop10h 52m

$421

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Mon 3/30

6:25 pm-4:58 am

2 stops11h 33m

Quito Mariscal Sucr

Wed 4/15

7:00 pm-12:51 pm

2 stops16h 51m

$425

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during November instead. Flights to South America in November, while not as cheap as those in September, still average around $497.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Raleigh to South America is on a Monday when prices can be found for as low as $594. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to South America for around $711.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Raleigh to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $521. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $742 on average. Flights to South America from Raleigh at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $586 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $560 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 14% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	6h 43m
Direct flights	None

The fastest flight from Raleigh to South America takes 6h 43m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 8 as of December 2025.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $242	Free Cancellation	Rating 6.3 8,186 reviews	Search Spirit Airlines flights
Copa Airlines	PriceFrom $245	Free Cancellation	Rating 7.6 1,556 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $282	Free Cancellation	Rating 7.5 1,891 reviews	Search LATAM Airlines flights
Delta	PriceFrom $282	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
American Airlines	PriceFrom $283	Free Cancellation	Rating 7.2 11,049 reviews	Search American Airlines flights
JetBlue	PriceFrom $297	Free Cancellation	Rating 7.2 2,895 reviews	Search JetBlue flights
United Airlines	PriceFrom $307	Free Cancellation	Rating 7.4 9,092 reviews	Search United Airlines flights
GOL	PriceFrom $540	Free Cancellation	Rating 7.3 1,131 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $275

Flights to Buenos Airesfrom $457

Flights to Sao Paulofrom $423

Flights to Bogotáfrom $178

Flights to Rio de Janeirofrom $472

Flights to Medellínfrom $187

Flights to Santiagofrom $378

Flights to Cartagenafrom $166

Flights to Quitofrom $227

Flights to Cuscofrom $417

Flights to Guayaquilfrom $187

Flights to Califrom $180

Cheap flights from Raleigh to South America from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to South America departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Raleigh to South America

Cheap round-trip flights

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Delta flights from Raleigh to South America

Our best Delta deals on Raleigh to South America flight tickets

Copa Airlines flights from Raleigh to South America

Our best Copa Airlines deals on Raleigh to South America flight tickets

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Use the filters below to find and compare flights from Raleigh to South America that are best for you.

How to get the cheapest flight ticket from Raleigh to South America

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Raleigh to South America is on a Monday when prices can be found for as low as $594. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to South America for around $711.

What is the cheapest time of day to depart on your flight to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 14% on your flight if you consider stops on a Raleigh to South America flight.

What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, American Airlines, and United Airlines are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time

Direct flights

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

How old do you have to be to fly from Raleigh-Durham Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

How can momondo help me find flights from Raleigh to South America?

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo