What is the cheapest airline that flies from Raleigh-Durham to South America?

Copa Airlines, United Airlines, and Delta are the most popular carriers operating from Raleigh-Durham to South America

What airlines fly to South America?

American Airlines, Copa Airlines and Delta are the top three most popular airlines that fly to South America from Raleigh according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?

Prices for flights from Raleigh-Durham Airport to South America refresh daily.

How many operators does momondo search for flights from Raleigh-Durham Airport to South America?

The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of August 2026.

How old do you have to be to fly from Raleigh-Durham Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$125 Cheap Flights from Raleigh to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Raleigh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:21 pm - 8:40 am

RDU

CTG

17h 19m

1 stop

6:20 am - 2:28 pm

CTG

RDU

7h 08m

1 stop

$297Copa Airlines

Mon, Sep 14 - Mon, Sep 21

4:21 pm - 8:40 am

RDU

CTG

17h 19m

1 stop

6:20 am - 2:28 pm

CTG

RDU

7h 08m

1 stop

$297Copa Airlines

Mon, Sep 28 - Wed, Oct 7

10:39 am - 10:10 pm

RDU

MDE

11h 31m

2 stops

10:40 am - 9:59 pm

MDE

RDU

11h 19m

1 stop

$321United Airlines

Wed, Nov 4 - Wed, Nov 11

6:10 am - 9:15 pm

RDU

MDE

16h 05m

1 stop

9:45 am - 9:59 pm

MDE

RDU

11h 14m

1 stop

$321United Airlines

Mon, Oct 26 - Thu, Oct 29

12:16 pm - 11:34 pm

RDU

MDE

11h 18m

1 stop

7:30 am - 8:13 pm

MDE

RDU

12h 43m

2 stops

$326American Airlines

Sun, Nov 8 - Wed, Nov 11

7:25 am - 1:15 pm

RDU

CTG

6h 50m

1 stop

3:30 pm - 12:28 am

CTG

RDU

8h 58m

1 stop

$339LATAM Airlines

Thu, Oct 29 - Thu, Nov 5

4:50 pm - 2:10 pm

RDU

CTG

21h 20m

1 stop

3:25 pm - 8:51 am

CTG

RDU

17h 26m

1 stop

$339LATAM Airlines

Thu, Jan 7 - Fri, Jan 15

7:00 am - 1:15 pm

RDU

CTG

7h 15m

1 stop

3:30 pm - 8:52 am

CTG

RDU

17h 22m

1 stop

$339Delta

Sat, Oct 31 - Sat, Nov 7

5:15 am - 2:15 pm

RDU

CTG

9h 00m

1 stop

3:25 pm - 12:26 am

CTG

RDU

9h 01m

1 stop

$339Delta

Sat, Nov 7 - Sat, Nov 21

5:00 am - 1:35 pm

RDU

CTG

8h 35m

1 stop

2:35 pm - 12:24 am

CTG

RDU

9h 49m

1 stop

$341American Airlines

Mon, Nov 9 - Fri, Nov 13

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LATAM Airlines flights from Raleigh to South America

Our best LATAM Airlines deals on Raleigh to South America flight tickets

LATAM Airlines

Oct 21

RDU8:10 amRaleigh-Durham

13h 00m

1 stop

BOG8:10 pmBogotá El Dorado

Nov 4

BOG10:45 amBogotá El Dorado

9h 08m

1 stop

RDU7:53 pmRaleigh-Durham

$341

LATAM Airlines

Sep 12

RDU7:25 amRaleigh-Durham

6h 40m

1 stop

CTG1:05 pmCartagena Rafael Nunez

Sep 19

CTG2:30 pmCartagena Rafael Nunez

17h 24m

1 stop

RDU8:54 amRaleigh-Durham

$342

LATAM Airlines

Oct 21

RDU8:10 amRaleigh-Durham

13h 00m

1 stop

BOG8:10 pmBogotá El Dorado

Nov 4

BOG10:45 amBogotá El Dorado

13h 43m

2 stops

RDU12:28 amRaleigh-Durham

$345

Copa Airlines flights from Raleigh to South America

Our best Copa Airlines deals on Raleigh to South America flight tickets

Copa Airlines

Sep 14

RDU4:21 pmRaleigh-Durham

17h 19m

1 stop

CTG8:40 amCartagena Rafael Nunez

Sep 21

CTG6:20 amCartagena Rafael Nunez

7h 08m

1 stop

RDU2:28 pmRaleigh-Durham

$297

Copa Airlines

Nov 4

RDU3:17 pmRaleigh-Durham

23h 28m

1 stop

MDE2:45 pmMedellín Jose Maria Cordova Intl

Nov 11

MDE5:00 amMedellín Jose Maria Cordova Intl

8h 27m

1 stop

RDU1:27 pmRaleigh-Durham

$309

Copa Airlines

Sep 16

RDU4:21 pmRaleigh-Durham

26h 34m

1 stop

CTG5:55 pmCartagena Rafael Nunez

Sep 21

CTG6:20 amCartagena Rafael Nunez

7h 08m

1 stop

RDU2:28 pmRaleigh-Durham

$324

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 9/14

4:21 pm-8:40 am

1 stop17h 19m

Cartagena Rafael Nunez

Mon 9/21

6:20 am-2:28 pm

1 stop7h 08m

$297

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 9/28

4:21 pm-8:40 am

1 stop17h 19m

Cartagena Rafael Nunez

Wed 10/7

6:20 am-2:28 pm

1 stop7h 08m

$297

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 11/4

10:39 am-10:10 pm

2 stops11h 31m

Medellín Jose Maria Cordova Intl

Wed 11/11

10:40 am-9:59 pm

1 stop11h 19m

$321

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 10/26

6:10 am-9:15 pm

1 stop16h 05m

Medellín Jose Maria Cordova Intl

Thu 10/29

9:45 am-9:59 pm

1 stop11h 14m

$321

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 11/8

12:16 pm-11:34 pm

1 stop11h 18m

Medellín Jose Maria Cordova Intl

Wed 11/11

7:30 am-8:13 pm

2 stops12h 43m

$326

Quickest round-trip

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 10/29

7:25 am-1:15 pm

1 stop6h 50m

Cartagena Rafael Nunez

Thu 11/5

3:30 pm-12:28 am

1 stop8h 58m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 1/7

4:50 pm-2:10 pm

1 stop21h 20m

Cartagena Rafael Nunez

Fri 1/15

3:25 pm-8:51 am

1 stop17h 26m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 10/31

7:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Sat 11/7

3:30 pm-8:52 am

1 stop17h 22m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 11/7

5:15 am-2:15 pm

1 stop9h 00m

Cartagena Rafael Nunez

Sat 11/21

3:25 pm-12:26 am

1 stop9h 01m

$339

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 11/9

5:00 am-1:35 pm

1 stop8h 35m

Cartagena Rafael Nunez

Fri 11/13

2:35 pm-12:24 am

1 stop9h 49m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Raleigh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Raleigh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $460. If you aren’t able to travel during the month of September, then book flights to South America from Raleigh during October instead. Flights to South America in October, while not as cheap as those in September, still average around $534.

How far in advance should I book a flight from Raleigh to South America?

You are more likely to see cheaper flights to South America from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $611 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Raleigh for as low as $539 on momondo.

Can stopping save me money on Raleigh to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Raleigh to South America flight.

Cheap Raleigh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to South America

Fastest flight time	6h 01m
Direct flights	None

The fastest flight from Raleigh to South America takes 6h 01m

There are no direct flights from Raleigh to South America. There are no popular flight routes from Raleigh to South America.

Search flight deals

Frequently asked questions about flying from Raleigh to South America

When did momondo last update prices for flights from Raleigh-Durham Airport to South America?
Prices for flights from Raleigh-Durham Airport to South America refresh daily.
How many operators does momondo search for flights from Raleigh-Durham Airport to South America?
The number of operators available for flights from Raleigh-Durham Airport to South America is 7 as of August 2026.
How old do you have to be to fly from Raleigh-Durham Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Raleigh to South America

Compare and see reviews for airlines that fly from Raleigh to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $102	Free Cancellation	Rating 7.8 8,490 reviews	Search Delta flights
JetBlue	PriceFrom $197	Free Cancellation	Rating 7.1 3,029 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $216	Free Cancellation	Rating 7.6 1,564 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $264	Free Cancellation	Rating 7.4 10,062 reviews	Search United Airlines flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.1 11,845 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $338	Free Cancellation	Rating 7.4 1,968 reviews	Search LATAM Airlines flights
GOL	PriceFrom $662	Free Cancellation	Rating 7.3 1,268 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to South America?

Finding the right flight to South America from Raleigh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Raleigh to South America with flexible booking policies on momondo?

Flights from Raleigh to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Raleigh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Raleigh to South America.

I’m not ready to book a flight from Raleigh to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Raleigh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.