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Cheap flights from Prague to Des Moines from $643

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Prague to Des Moines departing on 6/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Prague to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 8:34 pm
PRG
-
DSM
21h 34m
2 stops
United Airlines Logo
7:16 pm - 4:05 pm
DSM
-
PRG
13h 49m
2 stops
$1,049United Airlines
Fri, Apr 3 - Tue, Apr 7
Air Canada Logo
11:45 am - 11:17 pm
PRG
-
DSM
18h 32m
3 stops
Air Canada Logo
1:10 pm - 12:45 pm
DSM
-
PRG
16h 35m
3 stops
$1,509Air Canada
Fri, Apr 3 - Tue, Apr 7
Emirates Logo
4:10 pm - 9:25 pm
PRG
-
DSM
36h 15m
2 stops
Emirates Logo
3:30 pm - 8:15 pm
DSM
-
PRG
45h 45m
2 stops
$8,534Emirates
Fri, May 1 - Fri, May 8

momondo Fare Finder

 
Customize your flight search to find flights from Prague to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Prague to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Fri 4/3

6:00 am-8:34 pm

2 stops21h 34m

Des Moines

Tue 4/7

7:16 pm-4:05 pm

2 stops13h 49m

$1,049
Quickest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Fri 4/3

11:45 am-11:17 pm

3 stops18h 32m

Des Moines

Tue 4/7

1:10 pm-12:45 pm

3 stops16h 35m

$1,509

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Fri 5/1

4:10 pm-9:25 pm

2 stops36h 15m

Des Moines

Fri 5/8

3:30 pm-8:15 pm

2 stops45h 45m

$8,534
Cheapest one-way

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-12:12 am

2 stops20h 57m

$643

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-12:12 am

2 stops20h 57m

$676

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-12:12 am

2 stops20h 57m

$763
Quickest one-way

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-9:58 pm

1 stop18h 43m

$768

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

11:50 am-11:59 pm

2 stops43h 09m

$787

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-9:58 pm

1 stop18h 43m

$831

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Sat 6/27

10:15 am-9:58 pm

1 stop18h 43m

$840

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Prague to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Prague to Des Moines flights?

You could potentially save up to 9% on your flight if you consider stops on a Prague to Des Moines flight.

When to book flights from Prague to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Prague to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Prague to Des Moines (PRG to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Prague to Des Moines

Fastest flight time

32h 31m

Direct flights

None
The fastest flight from Prague to Des Moines takes 32h 31m
There are no direct flights from Prague to Des Moines. There are no popular flight routes from Prague to Des Moines.
Search flight deals

  • How far is Václav Havel Prague to Des Moines by plane?

    The straight-line distance from Václav Havel Prague to Des Moines is 4755.3 mi. Flights usually cover this in 32h 31m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Václav Havel Prague Airport to Des Moines Airport?

    Prices for flights from Václav Havel Prague Airport to Des Moines Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Václav Havel Prague Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Václav Havel Prague Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Prague to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Prague to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Prague to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Prague which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Prague to Des Moines?

momondo helps you find the best flight between Prague and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Prague to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Prague are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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