Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Prague to Des Moines from $1,014

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Prague to Des Moines departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Prague to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
4:28 pm - 11:15 pm
DSM
-
PRG
23h 47m
2 stops
$1,014American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
4:28 pm - 11:15 pm
DSM
-
PRG
23h 47m
2 stops
$1,017American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 11:44 pm
PRG
-
DSM
20h 29m
2 stops
American Airlines Logo
7:56 pm - 8:10 pm
DSM
-
PRG
17h 14m
2 stops
$1,018American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
4:28 pm - 11:15 pm
DSM
-
PRG
23h 47m
2 stops
$1,020American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 11:44 pm
PRG
-
DSM
20h 29m
2 stops
American Airlines Logo
7:56 pm - 8:10 pm
DSM
-
PRG
17h 14m
2 stops
$1,021American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 11:44 pm
PRG
-
DSM
20h 29m
2 stops
American Airlines Logo
7:56 pm - 8:10 pm
DSM
-
PRG
17h 14m
2 stops
$1,024American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
12:52 pm - 8:15 am
DSM
-
PRG
12h 23m
1 stop
$1,027American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
12:52 pm - 8:15 am
DSM
-
PRG
12h 23m
1 stop
$1,031American Airlines
Thu, Sep 3 - Sun, Sep 6
Emirates Logo
4:10 pm - 10:35 pm
PRG
-
DSM
37h 25m
2 stops
Emirates Logo
3:24 pm - 1:00 pm
DSM
-
PRG
38h 36m
2 stops
$3,073Emirates
Wed, Jul 29 - Wed, Aug 5

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Prague to Des Moines

Our best American Airlines deals on Prague to Des Moines flight tickets
American Airlines
Sep 3
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
Sep 6
DSM4:28 pmDes Moines
23h 47m
2 stops
PRG11:15 pmVáclav Havel Prague
$1,014
American Airlines
Sep 3
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
Sep 6
DSM4:28 pmDes Moines
23h 47m
2 stops
PRG11:15 pmVáclav Havel Prague
$1,017
American Airlines
Sep 3
PRG10:15 amVáclav Havel Prague
20h 29m
2 stops
DSM11:44 pmDes Moines
Sep 6
DSM7:56 pmDes Moines
17h 14m
2 stops
PRG8:10 pmVáclav Havel Prague
$1,018

momondo Fare Finder

 
Customize your flight search to find flights from Prague to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Prague to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Sun 9/6

4:28 pm-11:15 pm

2 stops23h 47m

$1,014

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Sun 9/6

4:28 pm-11:15 pm

2 stops23h 47m

$1,017

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-11:44 pm

2 stops20h 29m

Des Moines

Sun 9/6

7:56 pm-8:10 pm

2 stops17h 14m

$1,018

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Sun 9/6

4:28 pm-11:15 pm

2 stops23h 47m

$1,020

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-11:44 pm

2 stops20h 29m

Des Moines

Sun 9/6

7:56 pm-8:10 pm

2 stops17h 14m

$1,021

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-11:44 pm

2 stops20h 29m

Des Moines

Sun 9/6

7:56 pm-8:10 pm

2 stops17h 14m

$1,024
Quickest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Sun 9/6

12:52 pm-8:15 am

1 stop12h 23m

$1,027

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 9/3

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Sun 9/6

12:52 pm-8:15 am

1 stop12h 23m

$1,031

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Wed 7/29

4:10 pm-10:35 pm

2 stops37h 25m

Des Moines

Wed 8/5

3:24 pm-1:00 pm

2 stops38h 36m

$3,073

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Des Moines from

How to get the cheapest flight ticket from Prague to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Prague to Des Moines flights?

You could potentially save up to 23% on your flight if you consider stops on a Prague to Des Moines flight.

When to book flights from Prague to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Prague to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Prague to Des Moines (PRG to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Prague to Des Moines

Fastest flight time

37h 25m

Direct flights

None
The fastest flight from Prague to Des Moines takes 37h 25m
There are no direct flights from Prague to Des Moines. There are no popular flight routes from Prague to Des Moines.
Search flight deals

Frequently asked questions about flying from Prague to Des Moines

  • How far is Václav Havel Prague to Des Moines by plane?

    The straight-line distance from Václav Havel Prague to Des Moines is 4755.3 mi. Flights usually cover this in 37h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Václav Havel Prague Airport to Des Moines Airport?

    Prices for flights from Václav Havel Prague Airport to Des Moines Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Václav Havel Prague Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Václav Havel Prague Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Prague to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Prague to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Prague to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Prague which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Prague to Des Moines?

momondo helps you find the best flight between Prague and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Prague to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Prague are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 7/18
Sat 7/25
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States