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Cheap flights from Pittsburgh to South America from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Pittsburgh to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 1:15 pm
PIT
-
CTG
7h 15m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pm
CTG
-
PIT
9h 23m1 stop
$216Spirit Airlines
Wed, Jan 28 - Wed, Feb 4
Spirit Airlines Logo
5:50 pm - 1:15 pm
PIT
-
CTG
19h 25m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pm
CTG
-
PIT
9h 23m1 stop
$255Spirit Airlines
Sat, Jan 17 - Sat, Jan 24
American Airlines Logo
7:04 pm - 1:30 pm
PIT
-
CTG
18h 26m2 stops
American Airlines Logo
4:30 pm - 9:01 am
CTG
-
PIT
16h 31m2 stops
$291American Airlines
Fri, Jan 16 - Sat, Jan 24
American Airlines Logo
6:00 am - 3:30 pm
PIT
-
CTG
9h 30m1 stop
American Airlines Logo
2:30 pm - 9:33 am
CTG
-
PIT
19h 03m2 stops
$292American Airlines
Wed, Jan 28 - Wed, Feb 4
United Airlines Logo
8:10 pm - 10:05 pm
PIT
-
MDE
25h 55m2 stops
United Airlines Logo
10:45 am - 9:28 am
MDE
-
PIT
22h 43m2 stops
$308United Airlines
Mon, Feb 2 - Fri, Feb 6
United Airlines Logo
4:38 pm - 10:05 pm
PIT
-
MDE
29h 27m1 stop
United Airlines Logo
10:45 am - 1:10 pm
MDE
-
PIT
26h 25m2 stops
$315United Airlines
Mon, Feb 2 - Fri, Feb 6
LATAM Airlines Logo
7:00 am - 4:25 pm
PIT
-
BOG
10h 25m2 stops
LATAM Airlines Logo
11:00 am - 12:24 am
BOG
-
PIT
12h 24m2 stops
$449LATAM Airlines
Tue, May 5 - Tue, May 12
Delta Logo
1:41 pm - 9:35 pm
PIT
-
UIO
7h 54m1 stop
Delta Logo
11:45 pm - 12:36 pm
UIO
-
PIT
12h 51m1 stop
$564Delta
Mon, Feb 2 - Wed, Mar 4
Delta Logo
1:41 pm - 5:17 am
PIT
-
UIO
15h 36m2 stops
Delta Logo
11:45 pm - 3:56 pm
UIO
-
PIT
16h 11m1 stop
$569Delta
Mon, Feb 2 - Thu, Mar 5
LATAM Airlines Logo
11:30 am - 5:55 am
PIT
-
SCL
17h 25m1 stop
LATAM Airlines Logo
10:30 pm - 11:42 am
SCL
-
PIT
14h 12m1 stop
$714LATAM Airlines
Mon, Mar 9 - Wed, Mar 18

LATAM Airlines flights from Pittsburgh to South America

Our best LATAM Airlines deals on Pittsburgh to South America flight tickets
LATAM Airlines
May 5
PIT7:00 amPittsburgh
10h 25m
2 stops
BOG4:25 pmBogotá El Dorado
May 12
BOG11:00 amBogotá El Dorado
12h 24m
2 stops
PIT12:24 amPittsburgh
$449
Find similar
LATAM Airlines
Feb 2
PIT11:55 amPittsburgh
11h 21m
2 stops
CTG11:16 pmCartagena Rafael Nunez
Feb 4
CTG10:07 pmCartagena Rafael Nunez
20h 26m
2 stops
PIT6:33 pmPittsburgh
$506
Find similar
LATAM Airlines
Apr 2
PIT7:05 amPittsburgh
7h 10m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Apr 7
CTG2:30 pmCartagena Rafael Nunez
17h 33m
1 stop
PIT9:03 amPittsburgh
$541
Find similar

Avianca flights from Pittsburgh to South America

Our best Avianca deals on Pittsburgh to South America flight tickets
Avianca
May 5
PIT10:20 amPittsburgh
16h 35m
2 stops
BOG1:55 amBogotá El Dorado
May 12
BOG11:00 pmBogotá El Dorado
9h 36m
1 stop
PIT9:36 amPittsburgh
$542
Find similar
Avianca
Jan 30
PIT10:35 amPittsburgh
40h 15m
3 stops
UIO2:50 amQuito Mariscal Sucr
Mar 3
UIO4:00 amQuito Mariscal Sucr
29h 35m
2 stops
PIT9:35 amPittsburgh
$650
Find similar
Avianca
Dec 24
PIT10:55 amPittsburgh
22h 00m
2 stops
UIO8:55 amQuito Mariscal Sucr
Dec 27
UIO4:00 amQuito Mariscal Sucr
34h 03m
3 stops
PIT2:03 pmPittsburgh
$1,526
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Wed 1/28

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Wed 2/4

2:21 pm-11:44 pm

1 stop9h 23m

$216

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 1/17

5:50 pm-1:15 pm

1 stop19h 25m

Cartagena Rafael Nunez

Sat 1/24

2:21 pm-11:44 pm

1 stop9h 23m

$255

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 1/16

7:04 pm-1:30 pm

2 stops18h 26m

Cartagena Rafael Nunez

Sat 1/24

4:30 pm-9:01 am

2 stops16h 31m

$291

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Wed 1/28

6:00 am-3:30 pm

1 stop9h 30m

Cartagena Rafael Nunez

Wed 2/4

2:30 pm-9:33 am

2 stops19h 03m

$292

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/2

8:10 pm-10:05 pm

2 stops25h 55m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-9:28 am

2 stops22h 43m

$308

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/2

4:38 pm-10:05 pm

1 stop29h 27m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-1:10 pm

2 stops26h 25m

$315

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Tue 5/5

7:00 am-4:25 pm

2 stops10h 25m

Bogotá El Dorado

Tue 5/12

11:00 am-12:24 am

2 stops12h 24m

$449

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Mon 2/2

1:41 pm-9:35 pm

1 stop7h 54m

Quito Mariscal Sucr

Wed 3/4

11:45 pm-12:36 pm

1 stop12h 51m

$564

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Mon 2/2

1:41 pm-5:17 am

2 stops15h 36m

Quito Mariscal Sucr

Thu 3/5

11:45 pm-3:56 pm

1 stop16h 11m

$569

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 3/9

11:30 am-5:55 am

1 stop17h 25m

Santiago Arturo Merino Benitez

Wed 3/18

10:30 pm-11:42 am

1 stop14h 12m

$714

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during March instead. Flights to South America in March, while not as cheap as those in September, still average around $687.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Pittsburgh to South America is on a Monday when prices can be found for as low as $691. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Pittsburgh to South America for around $866.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Pittsburgh to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $635. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $796 on average. Flights to South America from Pittsburgh in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $772 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Pittsburgh for as low as $670 on momondo.

Can stopping save me money on Pittsburgh to South America flights?

You could potentially save up to 46% on your flight if you consider stops on a Pittsburgh to South America flight.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Fastest flight time

7h 18m

Direct flights

None
The fastest flight from Pittsburgh to South America takes 7h 18m
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
Search flight deals

  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $269Free CancellationRating
6.3
8,188 reviews
Search Spirit Airlines flights
JetBluePriceFrom $333Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
United AirlinesPriceFrom $347Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
American AirlinesPriceFrom $495Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $548Free CancellationRating
7.5
1,890 reviews
Search LATAM Airlines flights
DeltaPriceFrom $555Free CancellationRating
7.9
8,008 reviews
Search Delta flights
Copa AirlinesPriceFrom $712Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $275
Flights to Buenos Airesfrom $457
Flights to Sao Paulofrom $423
Flights to Bogotáfrom $178
Flights to Rio de Janeirofrom $472
Flights to Medellínfrom $187
Flights to Santiagofrom $378
Flights to Cartagenafrom $166
Flights to Quitofrom $227
Flights to Cuscofrom $417
Flights to Guayaquilfrom $187
Flights to Califrom $180