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Cheap flights from Pittsburgh to South America from $185

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 9/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Pittsburgh to South America

Cheap round-trip flights

Spirit Airlines Logo
6:45 am - 1:11 pmPIT-MDE
7h 26m1 stop
Spirit Airlines Logo
2:22 pm - 11:16 pmMDE-PIT
7h 54m1 stop
$260Spirit Airlines
Find Deal
Mon, Oct 6 - Tue, Oct 14
Spirit Airlines Logo
6:45 am - 1:11 pmPIT-MDE
7h 26m1 stop
Spirit Airlines Logo
1:12 am - 11:16 pmMDE-PIT
21h 04m1 stop
$267Spirit Airlines
Find Deal
Mon, Oct 6 - Mon, Oct 13
Delta Logo
7:00 am - 2:15 pmPIT-CTG
7h 15m1 stop
Delta Logo
3:30 pm - 11:13 pmCTG-PIT
7h 43m1 stop
$546Delta
Find Deal
Thu, Feb 19 - Mon, Feb 23
Delta Logo
6:00 am - 2:15 pmPIT-CTG
8h 15m1 stop
Delta Logo
3:30 pm - 11:13 pmCTG-PIT
7h 43m1 stop
$556Delta
Find Deal
Thu, Feb 19 - Mon, Feb 23
American Airlines Logo
6:30 am - 1:05 pmPIT-BOG
7h 35m1 stop
American Airlines Logo
12:05 am - 2:49 pmBOG-PIT
13h 44m1 stop
$560American Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 27
American Airlines Logo
12:14 pm - 9:17 pmPIT-BOG
10h 03m2 stops
American Airlines Logo
12:05 am - 2:09 pmBOG-PIT
13h 04m2 stops
$564American Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 27
United Airlines Logo
1:00 pm - 10:35 pmPIT-BOG
10h 35m1 stop
United Airlines Logo
1:30 am - 3:43 pmBOG-PIT
14h 13m1 stop
$566United Airlines
Find Deal
Sat, Oct 25 - Tue, Nov 4
United Airlines Logo
6:10 am - 8:41 amPIT-CTG
26h 31m2 stops
United Airlines Logo
9:42 am - 7:04 pmCTG-PIT
33h 22m2 stops
$585United Airlines
Find Deal
Thu, Feb 19 - Mon, Feb 23
LATAM Airlines Logo
11:45 am - 7:50 amPIT-SCL
19h 05m1 stop
LATAM Airlines Logo
11:55 pm - 4:55 pmSCL-PIT
18h 00m1 stop
$751LATAM Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
LATAM Airlines Logo
4:59 pm - 7:40 amPIT-SCL
13h 41m1 stop
LATAM Airlines Logo
11:40 pm - 11:44 amSCL-PIT
14h 04m1 stop
$807LATAM Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 4

Avianca flights from Pittsburgh to South America

Our best Avianca deals on Pittsburgh to South America flight tickets
Avianca
Oct 25
PIT8:08 pmPittsburgh
18h 32m
2 stops
BOG1:40 pmBogotá El Dorado
Nov 4
BOG4:00 amBogotá El Dorado
14h 49m
2 stops
PIT6:49 pmPittsburgh
$533
Find similar
Avianca
Sep 2
PIT10:45 amPittsburgh
16h 10m
2 stops
BOG1:55 amBogotá El Dorado
Sep 8
BOG3:59 amBogotá El Dorado
13h 49m
2 stops
PIT6:48 pmPittsburgh
$589
Find similar
Avianca
Sep 2
PIT10:45 amPittsburgh
10h 00m
1 stop
BOG7:45 pmBogotá El Dorado
Sep 8
BOG3:59 amBogotá El Dorado
13h 49m
2 stops
PIT6:48 pmPittsburgh
$603
Find similar

American Airlines flights from Pittsburgh to South America

Our best American Airlines deals on Pittsburgh to South America flight tickets
American Airlines
Oct 15
PIT6:30 amPittsburgh
7h 35m
1 stop
BOG1:05 pmBogotá El Dorado
Oct 27
BOG12:05 amBogotá El Dorado
13h 44m
1 stop
PIT2:49 pmPittsburgh
$560
Find similar
American Airlines
Oct 15
PIT12:14 pmPittsburgh
10h 03m
2 stops
BOG9:17 pmBogotá El Dorado
Oct 27
BOG12:05 amBogotá El Dorado
13h 04m
2 stops
PIT2:09 pmPittsburgh
$564
Find similar
American Airlines
Nov 29
PIT8:11 pmPittsburgh
19h 19m
2 stops
CTG3:30 pmCartagena Rafael Nunez
Dec 4
CTG8:00 amCartagena Rafael Nunez
10h 14m
2 stops
PIT6:14 pmPittsburgh
$608
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 30, 2025.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 10/6

6:45 am-1:11 pm

1 stop7h 26m

Medellín Jose Maria Cordova Intl

Tue 10/14

2:22 pm-11:16 pm

1 stop7h 54m

$260

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 10/6

6:45 am-1:11 pm

1 stop7h 26m

Medellín Jose Maria Cordova Intl

Mon 10/13

1:12 am-11:16 pm

1 stop21h 04m

$267

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Thu 2/19

7:00 am-2:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Mon 2/23

3:30 pm-11:13 pm

1 stop7h 43m

$546

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Thu 2/19

6:00 am-2:15 pm

1 stop8h 15m

Cartagena Rafael Nunez

Mon 2/23

3:30 pm-11:13 pm

1 stop7h 43m

$556

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Wed 10/15

6:30 am-1:05 pm

1 stop7h 35m

Bogotá El Dorado

Mon 10/27

12:05 am-2:49 pm

1 stop13h 44m

$560

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Wed 10/15

12:14 pm-9:17 pm

2 stops10h 03m

Bogotá El Dorado

Mon 10/27

12:05 am-2:09 pm

2 stops13h 04m

$564

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Sat 10/25

1:00 pm-10:35 pm

1 stop10h 35m

Bogotá El Dorado

Tue 11/4

1:30 am-3:43 pm

1 stop14h 13m

$566

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Thu 2/19

6:10 am-8:41 am

2 stops26h 31m

Cartagena Rafael Nunez

Mon 2/23

9:42 am-7:04 pm

2 stops33h 22m

$585

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Tue 9/23

11:45 am-7:50 am

1 stop19h 05m

Santiago Arturo Merino Benitez

Tue 9/30

11:55 pm-4:55 pm

1 stop18h 00m

$751

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sat 11/1

4:59 pm-7:40 am

1 stop13h 41m

Santiago Arturo Merino Benitez

Tue 11/4

11:40 pm-11:44 am

1 stop14h 04m

$807

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $614. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during March instead. Flights to South America in March, while not as cheap as those in September, still average around $682.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Pittsburgh to South America is on a Monday when prices can be found for as low as $691. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Pittsburgh to South America for around $866.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Pittsburgh to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $635. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $796 on average. Flights to South America from Pittsburgh in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $793 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Pittsburgh for as low as $665 on momondo.

Can stopping save me money on Pittsburgh to South America flights?

You could potentially save up to 59% on your flight if you consider stops on a Pittsburgh to South America flight.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Direct flights

None
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
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  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $279Free CancellationRating
6.3
8,019 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $453Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $497Free CancellationRating
7.9
7,978 reviews
Search Delta flights
LATAM AirlinesPriceFrom $508Free CancellationRating
7.5
1,844 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $518Free CancellationRating
7.4
8,942 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $712Free CancellationRating
7.5
1,517 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $280
Flights to Buenos Airesfrom $458
Flights to Bogotáfrom $178
Flights to Sao Paulofrom $368
Flights to Medellínfrom $170
Flights to Rio de Janeirofrom $368
Flights to Santiagofrom $312
Flights to Cartagenafrom $181
Flights to Quitofrom $306
Flights to Cuscofrom $360
Flights to Califrom $187
Flights to Guayaquilfrom $231