Cheap flights from Pittsburgh to South America from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:39 pm - 2:04 pm
PIT
-
CTG
19h 25m
2 stops
American Airlines Logo
1:25 pm - 1:04 pm
CTG
-
PIT
22h 39m
2 stops
$300American Airlines
Fri, May 8 - Tue, May 12
American Airlines Logo
7:16 pm - 12:09 pm
PIT
-
CTG
17h 53m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
CTG
-
PIT
7h 49m
1 stop
$303American Airlines
Sat, May 2 - Sun, May 10
Spirit Airlines Logo
6:00 am - 1:11 pm
PIT
-
BOG
8h 11m
1 stop
Spirit Airlines Logo
2:10 pm - 9:38 am
BOG
-
PIT
18h 28m
1 stop
$332Spirit Airlines
Tue, Apr 7 - Wed, Apr 8
Spirit Airlines Logo
6:00 am - 12:06 pm
PIT
-
CTG
7h 06m
1 stop
Spirit Airlines Logo
1:14 pm - 9:38 pm
CTG
-
PIT
7h 24m
1 stop
$339Spirit Airlines
Tue, Mar 24 - Wed, Apr 1
JetBlue Logo
6:00 am - 1:50 pm
PIT
-
CTG
8h 50m
1 stop
JetBlue Logo
2:05 pm - 10:45 pm
CTG
-
PIT
7h 40m
1 stop
$354JetBlue
Fri, Apr 17 - Fri, Apr 24
JetBlue Logo
7:00 am - 2:10 pm
PIT
-
MDE
8h 10m
1 stop
JetBlue Logo
1:20 pm - 10:45 pm
MDE
-
PIT
8h 25m
1 stop
$362JetBlue
Wed, May 6 - Thu, May 14
LATAM Airlines Logo
5:08 pm - 7:21 pm
PIT
-
UIO
27h 13m
2 stops
LATAM Airlines Logo
11:45 pm - 9:04 am
UIO
-
PIT
8h 19m
1 stop
$535LATAM Airlines
Tue, Mar 17 - Wed, Mar 18
LATAM Airlines Logo
5:08 pm - 6:21 pm
PIT
-
UIO
26h 13m
2 stops
LATAM Airlines Logo
11:45 pm - 10:47 am
UIO
-
PIT
10h 02m
1 stop
$555LATAM Airlines
Tue, Mar 17 - Wed, Mar 18
Delta Logo
6:00 am - 6:10 am
PIT
-
EZE
23h 10m
2 stops
Delta Logo
8:10 pm - 5:09 pm
EZE
-
PIT
21h 59m
1 stop
$1,047Delta
Wed, Jul 15 - Thu, Jul 23
Delta Logo
1:50 pm - 9:20 am
PIT
-
EZE
18h 30m
2 stops
Delta Logo
1:10 pm - 12:56 pm
EZE
-
PIT
24h 46m
2 stops
$1,051Delta
Mon, Jun 8 - Tue, Jun 16

Spirit Airlines flights from Pittsburgh to South America

Our best Spirit Airlines deals on Pittsburgh to South America flight tickets
Spirit Airlines
Apr 7
PIT6:00 amPittsburgh
8h 11m
1 stop
BOG1:11 pmBogotá El Dorado
Apr 8
BOG2:10 pmBogotá El Dorado
18h 28m
1 stop
PIT9:38 amPittsburgh
$332
Spirit Airlines
Mar 24
PIT6:00 amPittsburgh
7h 06m
1 stop
CTG12:06 pmCartagena Rafael Nunez
Apr 1
CTG1:14 pmCartagena Rafael Nunez
7h 24m
1 stop
PIT9:38 pmPittsburgh
$339
Spirit Airlines
Apr 20
PIT6:35 amPittsburgh
7h 37m
1 stop
BOG1:12 pmBogotá El Dorado
Apr 27
BOG2:07 pmBogotá El Dorado
8h 52m
1 stop
PIT11:59 pmPittsburgh
$342

LATAM Airlines flights from Pittsburgh to South America

Our best LATAM Airlines deals on Pittsburgh to South America flight tickets
LATAM Airlines
May 5
PIT7:05 amPittsburgh
7h 15m
1 stop
CTG1:20 pmCartagena Rafael Nunez
May 7
CTG2:13 pmCartagena Rafael Nunez
17h 49m
1 stop
PIT9:02 amPittsburgh
$359
LATAM Airlines
Apr 20
PIT7:05 amPittsburgh
17h 30m
2 stops
CTG11:35 pmCartagena Rafael Nunez
Apr 27
CTG5:30 amCartagena Rafael Nunez
26h 45m
2 stops
PIT9:15 amPittsburgh
$368
LATAM Airlines
Aug 19
PIT6:00 amPittsburgh
13h 45m
2 stops
CTG6:45 pmCartagena Rafael Nunez
Aug 23
CTG10:10 amCartagena Rafael Nunez
31h 33m
2 stops
PIT6:43 pmPittsburgh
$370

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 5/8

7:39 pm-2:04 pm

2 stops19h 25m

Cartagena Rafael Nunez

Tue 5/12

1:25 pm-1:04 pm

2 stops22h 39m

$300

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 5/2

7:16 pm-12:09 pm

1 stop17h 53m

Cartagena Rafael Nunez

Sun 5/10

3:10 pm-11:59 pm

1 stop7h 49m

$303

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Tue 4/7

6:00 am-1:11 pm

1 stop8h 11m

Bogotá El Dorado

Wed 4/8

2:10 pm-9:38 am

1 stop18h 28m

$332
Quickest round-trip

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Tue 3/24

6:00 am-12:06 pm

1 stop7h 06m

Cartagena Rafael Nunez

Wed 4/1

1:14 pm-9:38 pm

1 stop7h 24m

$339

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 4/17

6:00 am-1:50 pm

1 stop8h 50m

Cartagena Rafael Nunez

Fri 4/24

2:05 pm-10:45 pm

1 stop7h 40m

$354

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Wed 5/6

7:00 am-2:10 pm

1 stop8h 10m

Medellín Jose Maria Cordova Intl

Thu 5/14

1:20 pm-10:45 pm

1 stop8h 25m

$362

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/17

5:08 pm-7:21 pm

2 stops27h 13m

Quito Mariscal Sucr

Wed 3/18

11:45 pm-9:04 am

1 stop8h 19m

$535

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/17

5:08 pm-6:21 pm

2 stops26h 13m

Quito Mariscal Sucr

Wed 3/18

11:45 pm-10:47 am

1 stop10h 02m

$555

PittsburghBuenos Aires

PIT - EZE

PITEZE

Pittsburgh

Wed 7/15

6:00 am-6:10 am

2 stops23h 10m

Buenos Aires Ministro Pistarini

Thu 7/23

8:10 pm-5:09 pm

1 stop21h 59m

$1,047

PittsburghBuenos Aires

PIT - EZE

PITEZE

Pittsburgh

Mon 6/8

1:50 pm-9:20 am

2 stops18h 30m

Buenos Aires Ministro Pistarini

Tue 6/16

1:10 pm-12:56 pm

2 stops24h 46m

$1,051

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during March instead. Flights to South America in March, while not as cheap as those in September, still average around $660.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Fastest flight time

6h 31m

Direct flights

None
The fastest flight from Pittsburgh to South America takes 6h 31m
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $279Free CancellationRating
6.3
8,502 reviews
Search Spirit Airlines flights
JetBluePriceFrom $333Free CancellationRating
7.2
2,897 reviews
Search JetBlue flights
United AirlinesPriceFrom $347Free CancellationRating
7.4
9,406 reviews
Search United Airlines flights
DeltaPriceFrom $359Free CancellationRating
7.9
8,270 reviews
Search Delta flights
American AirlinesPriceFrom $392Free CancellationRating
7.1
11,398 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $575Free CancellationRating
7.4
1,917 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $617Free CancellationRating
7.5
1,565 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

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1 adult
Tue 4/7
Tue 4/14

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Popular flights according to clicks in the last 7 days on momondo