Cheap flights from Pittsburgh to South America from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 1:13 pm
PIT
-
MDE
8h 13m
1 stop
Spirit Airlines Logo
2:10 pm - 11:42 pm
MDE
-
PIT
8h 32m
1 stop
$235Spirit Airlines
Tue, May 5 - Tue, May 19
Spirit Airlines Logo
6:00 am - 1:10 pm
PIT
-
BOG
8h 10m
1 stop
Spirit Airlines Logo
2:05 pm - 11:42 pm
BOG
-
PIT
8h 37m
1 stop
$246Spirit Airlines
Mon, May 4 - Tue, May 19
American Airlines Logo
7:09 pm - 1:30 pm
PIT
-
CTG
18h 21m
2 stops
American Airlines Logo
3:15 pm - 10:22 am
CTG
-
PIT
18h 07m
2 stops
$270American Airlines
Mon, Mar 2 - Mon, Mar 9
American Airlines Logo
7:16 pm - 12:09 pm
PIT
-
CTG
17h 53m
1 stop
American Airlines Logo
1:25 pm - 11:56 pm
CTG
-
PIT
9h 31m
1 stop
$272American Airlines
Sun, May 3 - Thu, May 7
JetBlue Logo
6:00 am - 2:40 pm
PIT
-
CTG
8h 40m
1 stop
JetBlue Logo
2:35 pm - 10:52 pm
CTG
-
PIT
8h 17m
1 stop
$285JetBlue
Fri, Feb 20 - Fri, Feb 27
JetBlue Logo
6:00 am - 2:37 pm
PIT
-
CTG
8h 37m
1 stop
JetBlue Logo
2:35 pm - 10:52 pm
CTG
-
PIT
8h 17m
1 stop
$323JetBlue
Tue, Feb 24 - Wed, Feb 25
LATAM Airlines Logo
5:08 pm - 7:21 pm
PIT
-
UIO
27h 13m
2 stops
LATAM Airlines Logo
11:45 pm - 6:29 pm
UIO
-
PIT
17h 44m
1 stop
$533LATAM Airlines
Tue, Mar 17 - Wed, Mar 18
LATAM Airlines Logo
7:35 pm - 5:17 am
PIT
-
UIO
10h 42m
2 stops
LATAM Airlines Logo
6:50 pm - 10:47 am
UIO
-
PIT
14h 57m
2 stops
$580LATAM Airlines
Tue, Mar 24 - Tue, Mar 31
Delta Logo
10:30 am - 4:43 am
PIT
-
UIO
19h 13m
2 stops
Delta Logo
6:50 pm - 10:41 am
UIO
-
PIT
14h 51m
2 stops
$590Delta
Wed, Jun 10 - Wed, Jun 17
Delta Logo
7:00 am - 4:43 am
PIT
-
UIO
22h 43m
2 stops
Delta Logo
6:50 pm - 10:41 am
UIO
-
PIT
14h 51m
2 stops
$643Delta
Wed, Jun 10 - Wed, Jun 17

Spirit Airlines flights from Pittsburgh to South America

Our best Spirit Airlines deals on Pittsburgh to South America flight tickets
Spirit Airlines
May 5
PIT6:00 amPittsburgh
8h 13m
1 stop
MDE1:13 pmMedellín Jose Maria Cordova Intl
May 19
MDE2:10 pmMedellín Jose Maria Cordova Intl
8h 32m
1 stop
PIT11:42 pmPittsburgh
$235
Spirit Airlines
May 4
PIT6:00 amPittsburgh
8h 10m
1 stop
BOG1:10 pmBogotá El Dorado
May 19
BOG2:05 pmBogotá El Dorado
8h 37m
1 stop
PIT11:42 pmPittsburgh
$246
Spirit Airlines
Mar 2
PIT6:22 pmPittsburgh
19h 33m
1 stop
MDE1:55 pmMedellín Jose Maria Cordova Intl
Mar 5
MDE3:15 pmMedellín Jose Maria Cordova Intl
8h 44m
1 stop
PIT11:59 pmPittsburgh
$250

LATAM Airlines flights from Pittsburgh to South America

Our best LATAM Airlines deals on Pittsburgh to South America flight tickets
LATAM Airlines
Apr 2
PIT11:52 amPittsburgh
33h 38m
2 stops
CTG8:30 pmCartagena Rafael Nunez
Apr 7
CTG2:30 pmCartagena Rafael Nunez
17h 34m
1 stop
PIT9:04 amPittsburgh
$372
LATAM Airlines
Mar 1
PIT7:35 pmPittsburgh
18h 50m
1 stop
BOG2:25 pmBogotá El Dorado
Mar 3
BOG10:35 amBogotá El Dorado
12h 36m
2 stops
PIT11:11 pmPittsburgh
$408
LATAM Airlines
Mar 2
PIT6:00 amPittsburgh
8h 17m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Mar 9
CTG2:30 pmCartagena Rafael Nunez
26h 59m
1 stop
PIT6:29 pmPittsburgh
$409

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Tue 5/5

6:00 am-1:13 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Tue 5/19

2:10 pm-11:42 pm

1 stop8h 32m

$235

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Mon 5/4

6:00 am-1:10 pm

1 stop8h 10m

Bogotá El Dorado

Tue 5/19

2:05 pm-11:42 pm

1 stop8h 37m

$246

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Mon 3/2

7:09 pm-1:30 pm

2 stops18h 21m

Cartagena Rafael Nunez

Mon 3/9

3:15 pm-10:22 am

2 stops18h 07m

$270

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sun 5/3

7:16 pm-12:09 pm

1 stop17h 53m

Cartagena Rafael Nunez

Thu 5/7

1:25 pm-11:56 pm

1 stop9h 31m

$272

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 2/20

6:00 am-2:40 pm

1 stop8h 40m

Cartagena Rafael Nunez

Fri 2/27

2:35 pm-10:52 pm

1 stop8h 17m

$285

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Tue 2/24

6:00 am-2:37 pm

1 stop8h 37m

Cartagena Rafael Nunez

Wed 2/25

2:35 pm-10:52 pm

1 stop8h 17m

$323

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/17

5:08 pm-7:21 pm

2 stops27h 13m

Quito Mariscal Sucr

Wed 3/18

11:45 pm-6:29 pm

1 stop17h 44m

$533

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/24

7:35 pm-5:17 am

2 stops10h 42m

Quito Mariscal Sucr

Tue 3/31

6:50 pm-10:47 am

2 stops14h 57m

$580

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Wed 6/10

10:30 am-4:43 am

2 stops19h 13m

Quito Mariscal Sucr

Wed 6/17

6:50 pm-10:41 am

2 stops14h 51m

$590

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Wed 6/10

7:00 am-4:43 am

2 stops22h 43m

Quito Mariscal Sucr

Wed 6/17

6:50 pm-10:41 am

2 stops14h 51m

$643

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during April instead. Flights to South America in April, while not as cheap as those in September, still average around $673.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Fastest flight time

7h 13m

Direct flights

None
The fastest flight from Pittsburgh to South America takes 7h 13m
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $265Free CancellationRating
6.3
8,430 reviews
Search Spirit Airlines flights
JetBluePriceFrom $333Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
DeltaPriceFrom $359Free CancellationRating
7.9
8,173 reviews
Search Delta flights
American AirlinesPriceFrom $402Free CancellationRating
7.2
11,253 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $575Free CancellationRating
7.5
1,917 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $712Free CancellationRating
7.5
1,556 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $1,080Free CancellationRating
7.4
9,257 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

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1 adult
Tue 3/10
Tue 3/17

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