What is the cheapest airline that flies from Pittsburgh to South America?

Spirit Airlines, American Airlines, and United Airlines are the most popular carriers operating from Pittsburgh to South America

What airlines fly to South America?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to South America from Pittsburgh according to our data. American Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Pittsburgh Airport to South America?

Prices for flights from Pittsburgh Airport to South America refresh daily.

How many operators does momondo search for flights from Pittsburgh Airport to South America?

As of February 2026, there are 7 operators available to choose from for flights from Pittsburgh Airport to South America.

How old do you have to be to fly from Pittsburgh Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$119 Cheap Flights from Pittsburgh to South America in 2026

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Find the cheapest flights from Pittsburgh to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:55 pm - 12:09 pm

PIT

CTG

17h 14m

2 stops

3:10 pm - 1:04 pm

CTG

PIT

20h 54m

2 stops

$280American Airlines

Sat, May 2 - Sun, May 10

7:16 pm - 12:09 pm

PIT

CTG

17h 53m

1 stop

1:25 pm - 9:43 am

CTG

PIT

19h 18m

2 stops

$287American Airlines

Sat, May 2 - Sun, May 10

6:00 am - 2:13 pm

PIT

MDE

8h 13m

1 stop

3:15 pm - 11:59 pm

MDE

PIT

8h 44m

1 stop

$304Spirit Airlines

Tue, Mar 3 - Fri, Mar 6

9:09 pm - 2:13 pm

PIT

MDE

17h 04m

1 stop

3:15 pm - 11:59 pm

MDE

PIT

8h 44m

1 stop

$306Spirit Airlines

Mon, Mar 2 - Fri, Mar 6

7:00 am - 1:45 pm

PIT

MDE

7h 45m

1 stop

1:25 pm - 10:52 pm

MDE

PIT

8h 27m

1 stop

$346JetBlue

Tue, Mar 10 - Wed, Mar 18

7:30 am - 1:55 pm

PIT

MDE

7h 25m

1 stop

1:20 pm - 10:45 pm

MDE

PIT

8h 25m

1 stop

$347JetBlue

Mon, Apr 13 - Fri, Apr 24

4:54 pm - 2:17 pm

PIT

CTG

21h 23m

1 stop

5:05 am - 8:04 am

CTG

PIT

26h 59m

2 stops

$369LATAM Airlines

Sat, Feb 28 - Sat, Mar 7

7:05 am - 10:10 pm

PIT

BOG

16h 05m

2 stops

11:00 am - 12:35 am

BOG

PIT

12h 35m

2 stops

$452LATAM Airlines

Tue, Apr 14 - Mon, Apr 20

4:15 pm - 4:43 am

PIT

UIO

13h 28m

2 stops

6:50 pm - 1:01 pm

UIO

PIT

17h 11m

2 stops

$630Delta

Fri, Apr 3 - Sun, Apr 19

10:20 am - 9:45 am

PIT

EZE

22h 25m

1 stop

8:10 pm - 7:03 pm

EZE

PIT

23h 53m

1 stop

$1,037Delta

Thu, Apr 30 - Sun, May 31

United Airlines flights from Pittsburgh to South America

Our best United Airlines deals on Pittsburgh to South America flight tickets

United Airlines

Feb 24

PIT6:00 amPittsburgh

16h 05m

1 stop

MDE10:05 pmMedellín Jose Maria Cordova Intl

Feb 26

MDE10:45 amMedellín Jose Maria Cordova Intl

23h 01m

2 stops

PIT9:46 amPittsburgh

$352

United Airlines

Jun 16

PIT6:10 amPittsburgh

16h 00m

2 stops

MDE9:10 pmMedellín Jose Maria Cordova Intl

Jun 27

MDE9:45 amMedellín Jose Maria Cordova Intl

24h 39m

1 stop

PIT11:24 amPittsburgh

$360

United Airlines

Apr 12

PIT6:00 amPittsburgh

16h 10m

1 stop

MDE9:10 pmMedellín Jose Maria Cordova Intl

Apr 22

MDE9:45 amMedellín Jose Maria Cordova Intl

12h 59m

1 stop

PIT11:44 pmPittsburgh

$367

Spirit Airlines flights from Pittsburgh to South America

Our best Spirit Airlines deals on Pittsburgh to South America flight tickets

Spirit Airlines

Mar 3

PIT6:00 amPittsburgh

8h 13m

1 stop

MDE2:13 pmMedellín Jose Maria Cordova Intl

Mar 6

MDE3:15 pmMedellín Jose Maria Cordova Intl

8h 44m

1 stop

PIT11:59 pmPittsburgh

$304

Spirit Airlines

Mar 2

PIT9:09 pmPittsburgh

17h 04m

1 stop

MDE2:13 pmMedellín Jose Maria Cordova Intl

Mar 6

MDE3:15 pmMedellín Jose Maria Cordova Intl

8h 44m

1 stop

PIT11:59 pmPittsburgh

$306

Spirit Airlines

Mar 16

PIT6:00 amPittsburgh

8h 22m

1 stop

MDE1:22 pmMedellín Jose Maria Cordova Intl

Mar 20

MDE2:17 pmMedellín Jose Maria Cordova Intl

8h 07m

1 stop

PIT11:24 pmPittsburgh

$349

momondo Fare Finder

Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 5/2

7:55 pm-12:09 pm

2 stops17h 14m

Cartagena Rafael Nunez

Sun 5/10

3:10 pm-1:04 pm

2 stops20h 54m

$280

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 5/2

7:16 pm-12:09 pm

1 stop17h 53m

Cartagena Rafael Nunez

Sun 5/10

1:25 pm-9:43 am

2 stops19h 18m

$287

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Tue 3/3

6:00 am-2:13 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Fri 3/6

3:15 pm-11:59 pm

1 stop8h 44m

$304

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 3/2

9:09 pm-2:13 pm

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Fri 3/6

3:15 pm-11:59 pm

1 stop8h 44m

$306

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Tue 3/10

7:00 am-1:45 pm

1 stop7h 45m

Medellín Jose Maria Cordova Intl

Wed 3/18

1:25 pm-10:52 pm

1 stop8h 27m

$346

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 4/13

7:30 am-1:55 pm

1 stop7h 25m

Medellín Jose Maria Cordova Intl

Fri 4/24

1:20 pm-10:45 pm

1 stop8h 25m

$347

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 2/28

4:54 pm-2:17 pm

1 stop21h 23m

Cartagena Rafael Nunez

Sat 3/7

5:05 am-8:04 am

2 stops26h 59m

$369

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Tue 4/14

7:05 am-10:10 pm

2 stops16h 05m

Bogotá El Dorado

Mon 4/20

11:00 am-12:35 am

2 stops12h 35m

$452

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Fri 4/3

4:15 pm-4:43 am

2 stops13h 28m

Quito Mariscal Sucr

Sun 4/19

6:50 pm-1:01 pm

2 stops17h 11m

$630

PittsburghBuenos Aires

PIT - EZE

PITEZE

Pittsburgh

Thu 4/30

10:20 am-9:45 am

1 stop22h 25m

Buenos Aires Ministro Pistarini

Sun 5/31

8:10 pm-7:03 pm

1 stop23h 53m

$1,037

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during April instead. Flights to South America in April, while not as cheap as those in September, still average around $673.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Fastest flight time	7h 05m
Direct flights	None

The fastest flight from Pittsburgh to South America takes 7h 05m

There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.

Search flight deals

When did momondo last update prices for flights from Pittsburgh Airport to South America?
Prices for flights from Pittsburgh Airport to South America refresh daily.
How many operators does momondo search for flights from Pittsburgh Airport to South America?
As of February 2026, there are 7 operators available to choose from for flights from Pittsburgh Airport to South America.
How old do you have to be to fly from Pittsburgh Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $265	Free Cancellation	Rating 6.3 8,470 reviews	Search Spirit Airlines flights
JetBlue	PriceFrom $333	Free Cancellation	Rating 7.2 2,900 reviews	Search JetBlue flights
Delta	PriceFrom $359	Free Cancellation	Rating 7.9 8,209 reviews	Search Delta flights
American Airlines	PriceFrom $402	Free Cancellation	Rating 7.2 11,309 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $575	Free Cancellation	Rating 7.5 1,921 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $712	Free Cancellation	Rating 7.5 1,556 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $1,080	Free Cancellation	Rating 7.4 9,317 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.