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Cheap flights from Pittsburgh to South America from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
5:50 pm - 1:15 pmPIT-CTG
19h 25m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pmCTG-PIT
9h 23m1 stop
$311Spirit Airlines
Find Deal
sáb., ene. 17 - sáb., ene. 24
Spirit Airlines Logo
6:00 am - 1:13 pmPIT-CTG
7h 13m1 stop
Spirit Airlines Logo
2:21 pm - 11:42 pmCTG-PIT
9h 21m1 stop
$319Spirit Airlines
Find Deal
jue., feb. 19 - lun., feb. 23
United Airlines Logo
6:00 am - 9:05 pmPIT-MDE
16h 05m1 stop
United Airlines Logo
9:45 am - 11:13 pmMDE-PIT
12h 28m1 stop
$333United Airlines
Find Deal
lun., mar. 9 - mié., mar. 11
United Airlines Logo
6:15 am - 10:05 pmPIT-MDE
15h 50m2 stops
United Airlines Logo
10:45 am - 1:06 pmMDE-PIT
26h 21m2 stops
$338United Airlines
Find Deal
mar., dic. 9 - mar., dic. 16
Delta Logo
6:00 am - 2:17 pmPIT-CTG
8h 17m1 stop
Delta Logo
3:32 pm - 12:12 amCTG-PIT
8h 40m1 stop
$398Delta
Find Deal
mar., dic. 2 - mar., dic. 9
Delta Logo
6:00 am - 1:15 pmPIT-CTG
8h 15m1 stop
Delta Logo
5:05 am - 9:53 amCTG-PIT
27h 48m2 stops
$401Delta
Find Deal
mar., mar. 10 - vie., mar. 13
LATAM Airlines Logo
11:55 am - 9:35 pmPIT-UIO
9h 40m1 stop
LATAM Airlines Logo
11:45 pm - 9:15 amUIO-PIT
9h 30m1 stop
$564LATAM Airlines
Find Deal
lun., feb. 9 - mié., feb. 18
LATAM Airlines Logo
5:11 pm - 2:43 pmPIT-UIO
22h 32m2 stops
LATAM Airlines Logo
11:45 pm - 10:45 amUIO-PIT
10h 00m1 stop
$638LATAM Airlines
Find Deal
mar., mar. 17 - mié., mar. 18
American Airlines Logo
6:00 am - 11:02 pmPIT-UIO
17h 02m1 stop
American Airlines Logo
12:55 am - 3:34 pmUIO-PIT
14h 39m1 stop
$639American Airlines
Find Deal
mié., dic. 10 - mar., dic. 16
American Airlines Logo
6:51 pm - 10:15 amPIT-MVD
13h 24m1 stop
American Airlines Logo
11:25 pm - 6:06 pmMVD-PIT
20h 41m1 stop
$970American Airlines
Find Deal
mié., feb. 18 - mar., mar. 3

Copa Airlines flights from Pittsburgh to South America

Our best Copa Airlines deals on Pittsburgh to South America flight tickets
Copa Airlines
May 2
PIT6:20 amPittsburgh
27h 21m
2 stops
CTG8:41 amCartagena Rafael Nunez
May 10
CTG9:22 amCartagena Rafael Nunez
23h 14m
2 stops
PIT9:36 amPittsburgh
$525
Find similar
Copa Airlines
Feb 6
PIT10:35 amPittsburgh
13h 30m
2 stops
BOG12:05 amBogotá El Dorado
Feb 13
BOG2:24 pmBogotá El Dorado
18h 56m
2 stops
PIT9:20 amPittsburgh
$544
Find similar
Copa Airlines
Jan 17
PIT8:07 pmPittsburgh
20h 56m
2 stops
BOG5:03 pmBogotá El Dorado
Jan 23
BOG4:45 amBogotá El Dorado
14h 18m
2 stops
PIT7:03 pmPittsburgh
$549
Find similar

Spirit Airlines flights from Pittsburgh to South America

Our best Spirit Airlines deals on Pittsburgh to South America flight tickets
Spirit Airlines
Jan 17
PIT5:50 pmPittsburgh
19h 25m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Jan 24
CTG2:21 pmCartagena Rafael Nunez
9h 23m
1 stop
PIT11:44 pmPittsburgh
$311
Find similar
Spirit Airlines
Feb 19
PIT6:00 amPittsburgh
7h 13m
1 stop
CTG1:13 pmCartagena Rafael Nunez
Feb 23
CTG2:21 pmCartagena Rafael Nunez
9h 21m
1 stop
PIT11:42 pmPittsburgh
$319
Find similar
Spirit Airlines
Dec 11
PIT10:53 amPittsburgh
14h 16m
1 stop
MDE1:09 amMedellín Jose Maria Cordova Intl
Dec 17
MDE2:25 amMedellín Jose Maria Cordova Intl
7h 33m
1 stop
PIT9:58 amPittsburgh
$334
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

sáb. 1/17

5:50 pm-1:15 pm

1 stop19h 25m

Cartagena Rafael Nunez

sáb. 1/24

2:21 pm-11:44 pm

1 stop9h 23m

$311

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

jue. 2/19

6:00 am-1:13 pm

1 stop7h 13m

Cartagena Rafael Nunez

lun. 2/23

2:21 pm-11:42 pm

1 stop9h 21m

$319

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

lun. 3/9

6:00 am-9:05 pm

1 stop16h 05m

Medellín Jose Maria Cordova Intl

mié. 3/11

9:45 am-11:13 pm

1 stop12h 28m

$333

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

mar. 12/9

6:15 am-10:05 pm

2 stops15h 50m

Medellín Jose Maria Cordova Intl

mar. 12/16

10:45 am-1:06 pm

2 stops26h 21m

$338

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

mar. 12/2

6:00 am-2:17 pm

1 stop8h 17m

Cartagena Rafael Nunez

mar. 12/9

3:32 pm-12:12 am

1 stop8h 40m

$398

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

mar. 3/10

6:00 am-1:15 pm

1 stop8h 15m

Cartagena Rafael Nunez

vie. 3/13

5:05 am-9:53 am

2 stops27h 48m

$401

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

lun. 2/9

11:55 am-9:35 pm

1 stop9h 40m

Quito Mariscal Sucr

mié. 2/18

11:45 pm-9:15 am

1 stop9h 30m

$564

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

mar. 3/17

5:11 pm-2:43 pm

2 stops22h 32m

Quito Mariscal Sucr

mié. 3/18

11:45 pm-10:45 am

1 stop10h 00m

$638

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

mié. 12/10

6:00 am-11:02 pm

1 stop17h 02m

Quito Mariscal Sucr

mar. 12/16

12:55 am-3:34 pm

1 stop14h 39m

$639

PittsburghMontevideo

PIT - MVD

PITMVD

Pittsburgh

mié. 2/18

6:51 pm-10:15 am

1 stop13h 24m

Montevideo Carrasco

mar. 3/3

11:25 pm-6:06 pm

1 stop20h 41m

$970

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during March instead. Flights to South America in March, while not as cheap as those in September, still average around $687.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Pittsburgh to South America is on a Monday when prices can be found for as low as $691. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Pittsburgh to South America for around $866.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Pittsburgh to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $635. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $796 on average. Flights to South America from Pittsburgh in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $781 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Pittsburgh for as low as $634 on momondo.

Can stopping save me money on Pittsburgh to South America flights?

You could potentially save up to 46% on your flight if you consider stops on a Pittsburgh to South America flight.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Direct flights

None
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
Search flight deals

  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $265Free CancellationRating
6.3
8,139 reviews
Search Spirit Airlines flights
DeltaPriceFrom $419Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $488Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
United AirlinesPriceFrom $518Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $548Free CancellationRating
7.5
1,876 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $712Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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sáb. 12/13
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $291
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Flights to Bogotáfrom $182
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Flights to Rio de Janeirofrom $449
Flights to Medellínfrom $166
Flights to Santiagofrom $356
Flights to Cartagenafrom $175
Flights to Quitofrom $315
Flights to Cuscofrom $367
Flights to Guayaquilfrom $196
Flights to Califrom $187