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Cheap flights from Pittsburgh to South America from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 2/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
6:00 am - 1:15 pmPIT-CTG
7h 15m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pmCTG-PIT
9h 23m1 stop
$261Spirit Airlines
Find Deal
Mon, Jan 26 - Thu, Jan 29
Spirit Airlines Logo
6:00 am - 1:15 pmPIT-CTG
7h 15m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pmCTG-PIT
9h 23m1 stop
$262Spirit Airlines
Find Deal
Sat, Jan 17 - Sat, Jan 24
American Airlines Logo
5:42 pm - 1:30 pmPIT-CTG
19h 48m2 stops
American Airlines Logo
4:30 pm - 12:23 pmCTG-PIT
19h 53m2 stops
$291American Airlines
Find Deal
Fri, Jan 16 - Sat, Jan 24
Spirit Airlines Logo
7:59 am - 1:09 amPIT-MDE
17h 10m1 stop
Spirit Airlines Logo
2:05 am - 9:58 amMDE-PIT
7h 53m1 stop
$291Spirit Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11
American Airlines Logo
7:04 pm - 3:30 pmPIT-CTG
20h 26m2 stops
American Airlines Logo
4:30 pm - 11:10 amCTG-PIT
18h 40m1 stop
$298American Airlines
Find Deal
Fri, Jan 16 - Sat, Jan 24
United Airlines Logo
4:50 pm - 5:42 amPIT-MDE
12h 52m1 stop
United Airlines Logo
10:45 am - 10:14 pmMDE-PIT
11h 29m1 stop
$303United Airlines
Find Deal
Mon, Dec 8 - Fri, Dec 12
United Airlines Logo
5:51 pm - 5:42 amPIT-MDE
11h 51m2 stops
United Airlines Logo
1:15 am - 3:48 pmMDE-PIT
14h 33m1 stop
$308United Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11
LATAM Airlines Logo
11:49 am - 5:55 amPIT-SCL
17h 06m1 stop
LATAM Airlines Logo
6:30 pm - 12:55 pmSCL-PIT
19h 25m2 stops
$729LATAM Airlines
Find Deal
Mon, Mar 9 - Wed, Mar 18
LATAM Airlines Logo
11:49 am - 5:55 amPIT-SCL
17h 06m1 stop
LATAM Airlines Logo
12:20 am - 6:38 pmSCL-PIT
19h 18m2 stops
$732LATAM Airlines
Find Deal
Mon, Mar 9 - Tue, Mar 17
Delta Logo
1:50 pm - 7:20 amPIT-EZE
16h 30m1 stop
Delta Logo
10:25 pm - 4:40 pmEZE-PIT
19h 15m1 stop
$976Delta
Find Deal
Wed, Mar 11 - Wed, Mar 18

Copa Airlines flights from Pittsburgh to South America

Our best Copa Airlines deals on Pittsburgh to South America flight tickets
Copa Airlines
Feb 7
PIT8:07 pmPittsburgh
21h 19m
2 stops
BOG5:26 pmBogotá El Dorado
Feb 13
BOG4:45 amBogotá El Dorado
16h 19m
2 stops
PIT9:04 pmPittsburgh
$544
Find similar
Copa Airlines
Feb 19
PIT10:26 amPittsburgh
22h 15m
2 stops
CTG8:41 amCartagena Rafael Nunez
Feb 23
CTG9:42 amCartagena Rafael Nunez
23h 40m
2 stops
PIT9:22 amPittsburgh
$560
Find similar
Copa Airlines
Jan 8
PIT10:35 amPittsburgh
19h 10m
2 stops
BOG5:45 amBogotá El Dorado
Jan 16
BOG4:45 amBogotá El Dorado
15h 56m
2 stops
PIT8:41 pmPittsburgh
$569
Find similar

Spirit Airlines flights from Pittsburgh to South America

Our best Spirit Airlines deals on Pittsburgh to South America flight tickets
Spirit Airlines
Jan 26
PIT6:00 amPittsburgh
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Jan 29
CTG2:21 pmCartagena Rafael Nunez
9h 23m
1 stop
PIT11:44 pmPittsburgh
$261
Find similar
Spirit Airlines
Jan 17
PIT6:00 amPittsburgh
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Jan 24
CTG2:21 pmCartagena Rafael Nunez
9h 23m
1 stop
PIT11:44 pmPittsburgh
$262
Find similar
Spirit Airlines
Jan 14
PIT6:00 amPittsburgh
8h 07m
1 stop
BOG2:07 pmBogotá El Dorado
Jan 23
BOG3:06 pmBogotá El Dorado
18h 34m
1 stop
PIT9:40 amPittsburgh
$270
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Mon 1/26

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Thu 1/29

2:21 pm-11:44 pm

1 stop9h 23m

$261

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 1/17

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Sat 1/24

2:21 pm-11:44 pm

1 stop9h 23m

$262

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 1/16

5:42 pm-1:30 pm

2 stops19h 48m

Cartagena Rafael Nunez

Sat 1/24

4:30 pm-12:23 pm

2 stops19h 53m

$291

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 12/8

7:59 am-1:09 am

1 stop17h 10m

Medellín Jose Maria Cordova Intl

Thu 12/11

2:05 am-9:58 am

1 stop7h 53m

$291

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Fri 1/16

7:04 pm-3:30 pm

2 stops20h 26m

Cartagena Rafael Nunez

Sat 1/24

4:30 pm-11:10 am

1 stop18h 40m

$298

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 12/8

4:50 pm-5:42 am

1 stop12h 52m

Medellín Jose Maria Cordova Intl

Fri 12/12

10:45 am-10:14 pm

1 stop11h 29m

$303

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 12/8

5:51 pm-5:42 am

2 stops11h 51m

Medellín Jose Maria Cordova Intl

Thu 12/11

1:15 am-3:48 pm

1 stop14h 33m

$308

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 3/9

11:49 am-5:55 am

1 stop17h 06m

Santiago Arturo Merino Benitez

Wed 3/18

6:30 pm-12:55 pm

2 stops19h 25m

$729

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 3/9

11:49 am-5:55 am

1 stop17h 06m

Santiago Arturo Merino Benitez

Tue 3/17

12:20 am-6:38 pm

2 stops19h 18m

$732

PittsburghBuenos Aires

PIT - EZE

PITEZE

Pittsburgh

Wed 3/11

1:50 pm-7:20 am

1 stop16h 30m

Buenos Aires Ministro Pistarini

Wed 3/18

10:25 pm-4:40 pm

1 stop19h 15m

$976

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pittsburgh to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Pittsburgh to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of September, then book flights to South America from Pittsburgh during March instead. Flights to South America in March, while not as cheap as those in September, still average around $687.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Pittsburgh to South America is on a Monday when prices can be found for as low as $691. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Pittsburgh to South America for around $866.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Pittsburgh to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $635. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $796 on average. Flights to South America from Pittsburgh in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $780 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Pittsburgh for as low as $634 on momondo.

Can stopping save me money on Pittsburgh to South America flights?

You could potentially save up to 46% on your flight if you consider stops on a Pittsburgh to South America flight.

Cheap Pittsburgh to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to South America

Direct flights

None
There are no direct flights from Pittsburgh to South America. There are no popular flight routes from Pittsburgh to South America.
Search flight deals

  • When did momondo last update prices for flights from Pittsburgh Airport to South America?

    Prices for flights from Pittsburgh Airport to South America refresh daily.

  • How many operators does momondo search for flights from Pittsburgh Airport to South America?

  • How old do you have to be to fly from Pittsburgh Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pittsburgh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Pittsburgh to South America

Compare and see reviews for airlines that fly from Pittsburgh to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $265Free CancellationRating
6.3
8,158 reviews
Search Spirit Airlines flights
DeltaPriceFrom $419Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $488Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
United AirlinesPriceFrom $518Free CancellationRating
7.4
9,029 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $548Free CancellationRating
7.5
1,882 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $712Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Pittsburgh to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Pittsburgh to South America with flexible booking policies on momondo?

All flight searches from Pittsburgh to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Pittsburgh to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Pittsburgh to South America.

I’m not ready to book a flight from Pittsburgh to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pittsburgh to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $303
Flights to Buenos Airesfrom $528
Flights to Bogotáfrom $182
Flights to Sao Paulofrom $416
Flights to Rio de Janeirofrom $434
Flights to Medellínfrom $165
Flights to Santiagofrom $385
Flights to Cartagenafrom $175
Flights to Quitofrom $306
Flights to Cuscofrom $404
Flights to Guayaquilfrom $212
Flights to Califrom $187