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Cheap flights from Pittsburgh to Knoxville from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to Knoxville departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Pittsburgh to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:00 am - 1:04 pm
PIT
-
TYS
7h 04m
1 stop
Multiple Airlines Logo
9:36 pm - 11:59 pm
TYS
-
PIT
26h 23m
1 stop
$228Multiple Airlines
Sat, Feb 21 - Mon, Mar 2
Multiple Airlines Logo
6:00 am - 10:08 am
PIT
-
TYS
28h 08m
1 stop
Multiple Airlines Logo
11:50 am - 7:28 pm
TYS
-
PIT
7h 38m
1 stop
$237Multiple Airlines
Tue, Feb 17 - Thu, Feb 19
Multiple Airlines Logo
6:00 am - 2:10 pm
PIT
-
TYS
8h 10m
1 stop
Multiple Airlines Logo
11:30 am - 9:38 pm
TYS
-
PIT
10h 08m
1 stop
$242Multiple Airlines
Tue, Mar 24 - Wed, Mar 25
Multiple Airlines Logo
5:45 am - 6:31 pm
PIT
-
TYS
12h 46m
1 stop
Multiple Airlines Logo
9:36 pm - 4:39 pm
TYS
-
PIT
19h 03m
2 stops
$248Multiple Airlines
Mon, Mar 2 - Mon, Mar 9
Multiple Airlines Logo
9:09 pm - 10:10 am
PIT
-
TYS
13h 01m
1 stop
Multiple Airlines Logo
4:25 pm - 9:38 am
TYS
-
PIT
17h 13m
1 stop
$249Multiple Airlines
Mon, Mar 9 - Wed, Mar 11
Multiple Airlines Logo
6:00 am - 10:08 am
PIT
-
TYS
28h 08m
1 stop
Multiple Airlines Logo
5:56 pm - 2:22 pm
TYS
-
PIT
20h 26m
2 stops
$250Multiple Airlines
Tue, Feb 17 - Thu, Feb 19
Multiple Airlines Logo
6:00 am - 2:10 pm
PIT
-
TYS
8h 10m
1 stop
Multiple Airlines Logo
11:05 am - 11:29 pm
TYS
-
PIT
12h 24m
1 stop
$251Multiple Airlines
Tue, Mar 24 - Thu, Mar 26
Multiple Airlines Logo
6:00 am - 2:10 pm
PIT
-
TYS
8h 10m
1 stop
Multiple Airlines Logo
11:05 am - 11:29 pm
TYS
-
PIT
12h 24m
1 stop
$252Multiple Airlines
Tue, Mar 24 - Thu, Mar 26
Multiple Airlines Logo
6:00 am - 10:08 am
PIT
-
TYS
28h 08m
1 stop
Multiple Airlines Logo
3:52 pm - 11:59 pm
TYS
-
PIT
8h 07m
1 stop
$258Multiple Airlines
Tue, Feb 17 - Wed, Feb 18
Multiple Airlines Logo
9:09 pm - 10:10 am
PIT
-
TYS
13h 01m
1 stop
Multiple Airlines Logo
11:55 am - 6:45 pm
TYS
-
PIT
6h 50m
1 stop
$260Multiple Airlines
Mon, Mar 9 - Thu, Mar 12

Southwest flights from Pittsburgh to Knoxville

Our best Southwest deals on Pittsburgh to Knoxville flight tickets
Southwest
May 12
PIT6:40 amPittsburgh
10h 30m
2 stops
TYS5:10 pmKnoxville McGhee Tyson
May 18
TYS12:15 pmKnoxville McGhee Tyson
7h 45m
2 stops
PIT8:00 pmPittsburgh
$310
Southwest
Mar 23
PIT10:00 amPittsburgh
8h 45m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
Mar 25
TYS12:30 pmKnoxville McGhee Tyson
10h 10m
2 stops
PIT10:40 pmPittsburgh
$323
Southwest
May 9
PIT6:10 amPittsburgh
5h 30m
1 stop
TYS11:40 amKnoxville McGhee Tyson
May 15
TYS8:05 amKnoxville McGhee Tyson
10h 05m
2 stops
PIT6:10 pmPittsburgh
$324

United Airlines flights from Pittsburgh to Knoxville

Our best United Airlines deals on Pittsburgh to Knoxville flight tickets
United Airlines
Apr 13
PIT5:55 pmPittsburgh
4h 34m
1 stop
TYS10:29 pmKnoxville McGhee Tyson
Apr 16
TYS7:00 amKnoxville McGhee Tyson
6h 05m
1 stop
PIT1:05 pmPittsburgh
$281
United Airlines
Apr 13
PIT5:55 pmPittsburgh
4h 34m
1 stop
TYS10:29 pmKnoxville McGhee Tyson
Apr 16
TYS7:00 amKnoxville McGhee Tyson
6h 58m
2 stops
PIT1:58 pmPittsburgh
$286
United Airlines
Mar 24
PIT2:05 pmPittsburgh
6h 42m
1 stop
TYS8:47 pmKnoxville McGhee Tyson
Mar 25
TYS7:00 amKnoxville McGhee Tyson
6h 57m
2 stops
PIT1:57 pmPittsburgh
$308

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Pittsburgh to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 2/21

6:00 am-1:04 pm

1 stop7h 04m

Knoxville McGhee Tyson

Mon 3/2

9:36 pm-11:59 pm

1 stop26h 23m

$228

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 2/17

6:00 am-10:08 am

1 stop28h 08m

Knoxville McGhee Tyson

Thu 2/19

11:50 am-7:28 pm

1 stop7h 38m

$237

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 3/24

6:00 am-2:10 pm

1 stop8h 10m

Knoxville McGhee Tyson

Wed 3/25

11:30 am-9:38 pm

1 stop10h 08m

$242

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Mon 3/2

5:45 am-6:31 pm

1 stop12h 46m

Knoxville McGhee Tyson

Mon 3/9

9:36 pm-4:39 pm

2 stops19h 03m

$248

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Mon 3/9

9:09 pm-10:10 am

1 stop13h 01m

Knoxville McGhee Tyson

Wed 3/11

4:25 pm-9:38 am

1 stop17h 13m

$249

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 2/17

6:00 am-10:08 am

1 stop28h 08m

Knoxville McGhee Tyson

Thu 2/19

5:56 pm-2:22 pm

2 stops20h 26m

$250

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 3/24

6:00 am-2:10 pm

1 stop8h 10m

Knoxville McGhee Tyson

Thu 3/26

11:05 am-11:29 pm

1 stop12h 24m

$251

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 3/24

6:00 am-2:10 pm

1 stop8h 10m

Knoxville McGhee Tyson

Thu 3/26

11:05 am-11:29 pm

1 stop12h 24m

$252

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 2/17

6:00 am-10:08 am

1 stop28h 08m

Knoxville McGhee Tyson

Wed 2/18

3:52 pm-11:59 pm

1 stop8h 07m

$258

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Mon 3/9

9:09 pm-10:10 am

1 stop13h 01m

Knoxville McGhee Tyson

Thu 3/12

11:55 am-6:45 pm

1 stop6h 50m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Pittsburgh to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Pittsburgh, with most prices found around $238. If you aren’t able to travel during the month of August, then book flights to Knoxville from Pittsburgh during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $243.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $299 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Pittsburgh for as low as $236 on momondo.

How have Pittsburgh to Knoxville flight prices changed over time?

As of February 2026, prices for Pittsburgh to Knoxville flights are approximately 69% cheaper when compared to flights at the same time last year.

When to book flights from Pittsburgh to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Pittsburgh to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Pittsburgh to Knoxville (PIT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to Knoxville

Fastest flight time

3h 26m

Direct flights

None
The fastest flight from Pittsburgh to Knoxville takes 3h 26m
There are no direct flights from Pittsburgh to Knoxville. There are no popular flight routes from Pittsburgh to Knoxville.
Search flight deals

  • How far is Pittsburgh to Knoxville McGhee Tyson by plane?

    The straight-line distance from Pittsburgh to Knoxville McGhee Tyson is 375.4 mi. 3h 26m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pittsburgh Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Pittsburgh to Knoxville?

Best airlines flying from Pittsburgh to Knoxville

Compare and see reviews for airlines that fly from Pittsburgh to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $223Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights
United AirlinesPriceFrom $228Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.9
8,144 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Pittsburgh to Knoxville for you.

Can I find flights from Pittsburgh to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Pittsburgh to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Pittsburgh to Knoxville?

Once all potential Pittsburgh to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Pittsburgh to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Pittsburgh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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