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Cheap flights from Pittsburgh to Knoxville from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to Knoxville departing on 12/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Pittsburgh to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:00 am - 3:57 pm
PIT
-
TYS
9h 57m1 stop
Multiple Airlines Logo
11:59 am - 11:44 pm
TYS
-
PIT
11h 45m1 stop
$191Multiple Airlines
Wed, Feb 4 - Sat, Feb 7
Multiple Airlines Logo
10:53 am - 8:33 am
PIT
-
TYS
21h 40m1 stop
Multiple Airlines Logo
7:22 pm - 9:58 am
TYS
-
PIT
14h 36m1 stop
$214Multiple Airlines
Sun, Jan 4 - Tue, Jan 6
Multiple Airlines Logo
5:50 pm - 1:10 pm
PIT
-
TYS
19h 20m2 stops
Multiple Airlines Logo
11:59 am - 11:44 pm
TYS
-
PIT
11h 45m1 stop
$218Multiple Airlines
Wed, Feb 4 - Sat, Feb 7
Multiple Airlines Logo
11:00 am - 11:05 pm
PIT
-
TYS
12h 05m1 stop
Multiple Airlines Logo
1:39 pm - 9:28 pm
TYS
-
PIT
7h 49m2 stops
$229Multiple Airlines
Sun, Jan 11 - Sun, Jan 18
Multiple Airlines Logo
10:53 am - 8:39 am
PIT
-
TYS
21h 46m1 stop
Multiple Airlines Logo
5:59 pm - 9:40 am
TYS
-
PIT
15h 41m1 stop
$230Multiple Airlines
Wed, Jan 7 - Sat, Jan 10
Multiple Airlines Logo
5:50 pm - 5:28 pm
PIT
-
TYS
23h 38m2 stops
Multiple Airlines Logo
1:39 pm - 9:28 pm
TYS
-
PIT
7h 49m2 stops
$235Multiple Airlines
Sun, Jan 11 - Sun, Jan 18
Delta Logo
8:00 am - 1:50 pm
PIT
-
TYS
5h 50m1 stop
Delta Logo
1:00 pm - 6:32 pm
TYS
-
PIT
5h 32m1 stop
$237Delta
Tue, Jan 13 - Tue, Jan 20
American Airlines Logo
7:45 am - 1:54 pm
PIT
-
TYS
6h 09m2 stops
American Airlines Logo
2:17 pm - 6:14 pm
TYS
-
PIT
3h 57m1 stop
$242American Airlines
Tue, Jan 13 - Tue, Jan 20
American Airlines Logo
1:48 pm - 8:56 pm
PIT
-
TYS
7h 08m1 stop
American Airlines Logo
6:00 am - 12:55 pm
TYS
-
PIT
6h 55m1 stop
$243American Airlines
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
7:45 am - 1:54 pm
PIT
-
TYS
6h 09m2 stops
American Airlines Logo
6:00 am - 9:47 am
TYS
-
PIT
3h 47m1 stop
$256American Airlines
Wed, Jan 7 - Sat, Jan 10

United Airlines flights from Pittsburgh to Knoxville

Our best United Airlines deals on Pittsburgh to Knoxville flight tickets
United Airlines
Feb 18
PIT2:05 pmPittsburgh
6h 52m
1 stop
TYS8:57 pmKnoxville McGhee Tyson
Feb 21
TYS7:25 pmKnoxville McGhee Tyson
3h 50m
1 stop
PIT11:15 pmPittsburgh
$297
Find similar
United Airlines
Feb 18
PIT11:23 amPittsburgh
9h 34m
2 stops
TYS8:57 pmKnoxville McGhee Tyson
Feb 21
TYS9:10 amKnoxville McGhee Tyson
6h 35m
1 stop
PIT3:45 pmPittsburgh
$302
Find similar
United Airlines
Jan 16
PIT4:38 pmPittsburgh
7h 06m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Jan 20
TYS2:25 pmKnoxville McGhee Tyson
9h 13m
2 stops
PIT11:38 pmPittsburgh
$335
Find similar

American Airlines flights from Pittsburgh to Knoxville

Our best American Airlines deals on Pittsburgh to Knoxville flight tickets
American Airlines
Jan 13
PIT7:45 amPittsburgh
6h 09m
2 stops
TYS1:54 pmKnoxville McGhee Tyson
Jan 20
TYS2:17 pmKnoxville McGhee Tyson
3h 57m
1 stop
PIT6:14 pmPittsburgh
$242
Find similar
American Airlines
Jan 15
PIT1:48 pmPittsburgh
7h 08m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
Jan 18
TYS6:00 amKnoxville McGhee Tyson
6h 55m
1 stop
PIT12:55 pmPittsburgh
$243
Find similar
American Airlines
Jan 7
PIT7:45 amPittsburgh
6h 09m
2 stops
TYS1:54 pmKnoxville McGhee Tyson
Jan 10
TYS6:00 amKnoxville McGhee Tyson
3h 47m
1 stop
PIT9:47 amPittsburgh
$256
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Pittsburgh to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 2/4

6:00 am-3:57 pm

1 stop9h 57m

Knoxville McGhee Tyson

Sat 2/7

11:59 am-11:44 pm

1 stop11h 45m

$191

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sun 1/4

10:53 am-8:33 am

1 stop21h 40m

Knoxville McGhee Tyson

Tue 1/6

7:22 pm-9:58 am

1 stop14h 36m

$214

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 2/4

5:50 pm-1:10 pm

2 stops19h 20m

Knoxville McGhee Tyson

Sat 2/7

11:59 am-11:44 pm

1 stop11h 45m

$218

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sun 1/11

11:00 am-11:05 pm

1 stop12h 05m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:28 pm

2 stops7h 49m

$229

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 1/7

10:53 am-8:39 am

1 stop21h 46m

Knoxville McGhee Tyson

Sat 1/10

5:59 pm-9:40 am

1 stop15h 41m

$230

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sun 1/11

5:50 pm-5:28 pm

2 stops23h 38m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:28 pm

2 stops7h 49m

$235

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 1/13

8:00 am-1:50 pm

1 stop5h 50m

Knoxville McGhee Tyson

Tue 1/20

1:00 pm-6:32 pm

1 stop5h 32m

$237

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 1/13

7:45 am-1:54 pm

2 stops6h 09m

Knoxville McGhee Tyson

Tue 1/20

2:17 pm-6:14 pm

1 stop3h 57m

$242

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Thu 1/15

1:48 pm-8:56 pm

1 stop7h 08m

Knoxville McGhee Tyson

Sun 1/18

6:00 am-12:55 pm

1 stop6h 55m

$243

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 1/7

7:45 am-1:54 pm

2 stops6h 09m

Knoxville McGhee Tyson

Sat 1/10

6:00 am-9:47 am

1 stop3h 47m

$256

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Pittsburgh to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Pittsburgh, with most prices found around $238. If you aren’t able to travel during the month of August, then book flights to Knoxville from Pittsburgh during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $243.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Pittsburgh to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $237. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Pittsburgh to Knoxville for around $392.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Pittsburgh to Knoxville when you can find flight prices for as low as $268. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $392.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $296 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Pittsburgh for as low as $152 on momondo.

How have Pittsburgh to Knoxville flight prices changed over time?

As of December 2025, prices for Pittsburgh to Knoxville flights are approximately 32% cheaper when compared to flights at the same time last year.

When to book flights from Pittsburgh to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Pittsburgh to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Pittsburgh to Knoxville (PIT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to Knoxville

Fastest flight time

3h 51m

Direct flights

None
The fastest flight from Pittsburgh to Knoxville takes 3h 51m
There are no direct flights from Pittsburgh to Knoxville. There are no popular flight routes from Pittsburgh to Knoxville.
Search flight deals

  • How far is Pittsburgh to Knoxville McGhee Tyson by plane?

    The straight-line distance from Pittsburgh to Knoxville McGhee Tyson is 375.4 mi. 3h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Pittsburgh Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pittsburgh Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Pittsburgh to Knoxville?

Best airlines flying from Pittsburgh to Knoxville

Compare and see reviews for airlines that fly from Pittsburgh to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
United AirlinesPriceFrom $228Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Pittsburgh to Knoxville for you.

Can I find flights from Pittsburgh to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Pittsburgh to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Pittsburgh to Knoxville?

Once all potential Pittsburgh to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Pittsburgh to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Pittsburgh. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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