What is the cheapest airline that flies from Panama to Missouri?

United Airlines and American Airlines are the most popular carriers operating from Panama to Missouri

When did momondo last update prices for flights from Panama to Missouri?

Prices for flights from Panama to Missouri refresh daily.

How many operators does momondo search for flights from Panama to Missouri?

As of December 2025, there are 2 operators available to choose from for flights from Panama to Missouri.

How old do you have to be to fly from Panama to Missouri?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Missouri.

What documentation or ID do you need to fly to Missouri?

The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$258 Cheap Flights from Panama to Missouri in 2025/26

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Find the cheapest flights from Panama to Missouri

Round-trip

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Recent round-trip flight deals from Panama to Missouri

Enter your travel dates to find the best prices.

11:35 am - 9:32 am

PTY

MCI

22h 57m1 stop

6:15 am - 5:07 pm

MCI

PTY

9h 52m1 stop

$418United Airlines

Thu, Feb 19 - Mon, Feb 23

4:41 pm - 2:02 pm

PTY

MCI

22h 21m1 stop

10:15 am - 5:07 pm

MCI

PTY

29h 52m1 stop

$438United Airlines

Fri, Feb 20 - Wed, Feb 25

2:50 pm - 10:06 am

PTY

MCI

20h 16m2 stops

12:30 pm - 1:50 pm

MCI

PTY

24h 20m2 stops

$441American Airlines

Thu, Feb 19 - Mon, Feb 23

4:41 pm - 9:31 am

PTY

MCI

17h 50m1 stop

10:30 am - 7:38 pm

MCI

PTY

8h 08m1 stop

$458United Airlines

Thu, Jan 22 - Mon, Jan 26

8:55 am - 10:40 pm

PTY

MCI

14h 45m1 stop

6:30 pm - 5:07 pm

MCI

PTY

21h 37m2 stops

$463United Airlines

Thu, Jan 22 - Mon, Jan 26

4:05 pm - 11:59 pm

PTY

MCI

8h 54m1 stop

12:30 pm - 1:50 pm

MCI

PTY

24h 20m2 stops

$509American Airlines

Thu, Feb 19 - Mon, Feb 23

4:05 pm - 11:59 pm

PTY

MCI

8h 54m1 stop

5:40 pm - 1:50 pm

MCI

PTY

19h 10m1 stop

$571American Airlines

Thu, Feb 19 - Mon, Feb 23

3:20 pm - 11:39 pm

PTY

STL

9h 19m1 stop

6:55 pm - 1:55 pm

STL

PTY

18h 00m1 stop

$832Delta

Thu, Jan 8 - Mon, Jan 12

3:20 pm - 11:39 pm

PTY

STL

9h 19m1 stop

6:55 pm - 1:55 pm

STL

PTY

18h 00m1 stop

$903Delta

Thu, Jan 8 - Mon, Jan 12

2:20 pm - 10:35 pm

PTY

SGF

8h 15m1 stop

6:00 am - 1:07 pm

SGF

PTY

7h 07m1 stop

$1,039Delta

Wed, Jun 17 - Tue, Jul 7

Delta flights from Panama to Missouri

Our best Delta deals on Panama to Missouri flight tickets

Delta

Jan 8

PTY3:20 pmPanama City Tocumen Intl

9h 19m

1 stop

STL11:39 pmLambert-St Louis

Jan 12

STL6:55 pmLambert-St Louis

18h 00m

1 stop

PTY1:55 pmPanama City Tocumen Intl

$832

Find similar

Delta

Jan 8

PTY3:20 pmPanama City Tocumen Intl

9h 19m

1 stop

STL11:39 pmLambert-St Louis

Jan 12

STL6:55 pmLambert-St Louis

18h 00m

1 stop

PTY1:55 pmPanama City Tocumen Intl

$903

Find similar

Delta

Jun 17

PTY2:20 pmPanama City Tocumen Intl

8h 15m

1 stop

SGF10:35 pmSpringfield-Branson

Jul 7

SGF6:00 amSpringfield-Branson

7h 07m

1 stop

PTY1:07 pmPanama City Tocumen Intl

$1,039

Find similar

United Airlines flights from Panama to Missouri

Our best United Airlines deals on Panama to Missouri flight tickets

United Airlines

Feb 19

PTY4:41 pmPanama City Tocumen Intl

17h 51m

1 stop

MCI9:32 amKansas City

Feb 23

MCI3:22 pmKansas City

22h 23m

2 stops

PTY2:45 pmPanama City Tocumen Intl

$418

Find similar

United Airlines

Jan 22

PTY8:55 amPanama City Tocumen Intl

14h 45m

1 stop

MCI10:40 pmKansas City

Jan 25

MCI6:30 pmKansas City

19h 15m

2 stops

PTY2:45 pmPanama City Tocumen Intl

$463

Find similar

United Airlines

Jan 22

PTY4:41 pmPanama City Tocumen Intl

17h 50m

1 stop

MCI9:31 amKansas City

Jan 25

MCI3:00 pmKansas City

25h 07m

1 stop

PTY5:07 pmPanama City Tocumen Intl

$475

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 2/19

11:35 am-9:32 am

1 stop22h 57m

Kansas City

Mon 2/23

6:15 am-5:07 pm

1 stop9h 52m

$418

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Fri 2/20

4:41 pm-2:02 pm

1 stop22h 21m

Kansas City

Wed 2/25

10:15 am-5:07 pm

1 stop29h 52m

$438

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 2/19

2:50 pm-10:06 am

2 stops20h 16m

Kansas City

Mon 2/23

12:30 pm-1:50 pm

2 stops24h 20m

$441

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 1/22

4:41 pm-9:31 am

1 stop17h 50m

Kansas City

Mon 1/26

10:30 am-7:38 pm

1 stop8h 08m

$458

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 1/22

8:55 am-10:40 pm

1 stop14h 45m

Kansas City

Mon 1/26

6:30 pm-5:07 pm

2 stops21h 37m

$463

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 2/19

4:05 pm-11:59 pm

1 stop8h 54m

Kansas City

Mon 2/23

12:30 pm-1:50 pm

2 stops24h 20m

$509

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 2/19

4:05 pm-11:59 pm

1 stop8h 54m

Kansas City

Mon 2/23

5:40 pm-1:50 pm

1 stop19h 10m

$571

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 1/8

3:20 pm-11:39 pm

1 stop9h 19m

Lambert-St Louis

Mon 1/12

6:55 pm-1:55 pm

1 stop18h 00m

$832

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 1/8

3:20 pm-11:39 pm

1 stop9h 19m

Lambert-St Louis

Mon 1/12

6:55 pm-1:55 pm

1 stop18h 00m

$903

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Wed 6/17

2:20 pm-10:35 pm

1 stop8h 15m

Springfield-Branson

Tue 7/7

6:00 am-1:07 pm

1 stop7h 07m

$1,039

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, June is the cheapest month to fly from Panama to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you aren’t able to travel to Missouri during the month of June, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $398.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Panama to Missouri is on a Thursday when prices can be found for as low as $496. Flights from Panama to Missouri on a Wednesday will generally be more expensive and average around $611. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Panama to Missouri at noon for as low as $535. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $574. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Panama to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Missouri

Fastest flight time	8h 15m
Direct flights	None

The fastest flight from Panama to Missouri takes 8h 15m

There are no direct flights from Panama to Missouri. There are no popular flight routes from Panama to Missouri.

Search flight deals

When did momondo last update prices for flights from Panama to Missouri?
Prices for flights from Panama to Missouri refresh daily.
How many operators does momondo search for flights from Panama to Missouri?
As of December 2025, there are 2 operators available to choose from for flights from Panama to Missouri.
How old do you have to be to fly from Panama to Missouri?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Panama to Missouri

Compare and see reviews for airlines that fly from Panama to Missouri with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $418	Free Cancellation	Rating 7.4 9,113 reviews		Search United Airlines flights
American Airlines	PriceFrom $431	Free Cancellation	Rating 7.2 11,073 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Panama.

Can I find flights from Panama to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Missouri?

momondo helps you find the best flight between Panama and Missouri by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.