Cheap flights from Panama to Illinois from $207

The cheapest month to fly to Illinois from Panama is in July. Flight prices, which tend to average around $405, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of July, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $413.

The cheapest day to depart from Panama to Illinois is on a Wednesday when prices can be found for as low as $493. Flights from Panama to Illinois on a Sunday will generally be more expensive and average around $917. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our most recent data shows that the best time of day to fly to Illinois is in the afternoon. Flights from Panama to Illinois during this time can be as low as $496. Flights in the morning are often more expensive with an average ticket price of $741.

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama - Illinois flight prices

You are more likely to see cheaper flights to Illinois from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $590 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Panama for as low as $478 on momondo.

There are 2 cabin classes available to choose from on Panama to Illinois flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

The number of flights available between Panama and Illinois is 3 per day as of April 2026. The most frequent departure time is 7:00AM, with 60% of daily flights leaving at noon.

The number of flights available between Panama and Illinois is 27 per week as of April 2026. The most frequent departure day is Mon, with 19% of weekly flights leaving on this day.