Cheap flights from Panama to Illinois from $318

The cheapest month to fly to Illinois from Panama is in November. Flight prices, which tend to average around $239, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $239.

The cheapest day to depart from Panama to Illinois is on a Saturday when prices can be found for as low as $574. Flights from Panama to Illinois on a Sunday will generally be more expensive and average around $887. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our most recent data shows that the best time of day to fly to Illinois is in the afternoon. Flights from Panama to Illinois during this time can be as low as $496. Flights in the morning are often more expensive with an average ticket price of $762.

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama - Illinois flight prices

You are more likely to see cheaper flights to Illinois from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $627 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Panama for as low as $474 on momondo.

There are 2 cabin classes available to choose from on Panama to Illinois flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

The number of flights available between Panama and Illinois is 3 per day as of June 2026. The most frequent departure time is 7:00PM, with 66% of daily flights leaving in the evening.

The number of flights available between Panama and Illinois is 25 per week as of June 2026. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.