What is the cheapest airline that flies from Panama City Tocumen Intl to South Carolina?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Panama City Tocumen Intl to South Carolina

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to South Carolina?

Prices for flights from Panama City Tocumen Intl Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to South Carolina?

The number of operators available for flights from Panama City Tocumen Intl Airport to South Carolina is 2 as of July 2026.

How old do you have to be to fly from Panama City Tocumen Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$288 Cheap Flights from Panama City to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:20 pm - 11:57 pm

PTY

CLT

8h 37m

1 stop

6:40 am - 12:58 pm

CLT

PTY

7h 18m

1 stop

$551Delta

Wed, Sep 2 - Wed, Sep 16

6:41 pm - 9:44 am

PTY

CLT

14h 03m

1 stop

6:00 am - 1:31 pm

CLT

PTY

8h 31m

1 stop

$560Copa Airlines

Sat, Sep 26 - Fri, Oct 16

4:41 pm - 9:54 pm

PTY

CHS

29h 13m

1 stop

6:05 am - 7:38 pm

CHS

PTY

13h 33m

2 stops

$562United Airlines

Mon, Dec 21 - Thu, Jan 21

9:45 am - 10:08 am

PTY

CLT

23h 23m

2 stops

7:00 am - 7:31 pm

CLT

PTY

13h 31m

1 stop

$564United Airlines

Thu, Sep 24 - Mon, Sep 28

5:30 am - 5:12 pm

PTY

CLT

10h 42m

2 stops

6:48 pm - 1:55 am

CLT

PTY

32h 07m

3 stops

$567Multiple Airlines

Thu, Jul 23 - Wed, Jul 29

1:16 pm - 10:20 am

PTY

CLT

20h 04m

1 stop

9:55 pm - 12:26 pm

CLT

PTY

15h 31m

1 stop

$569American Airlines

Thu, Sep 10 - Mon, Sep 14

1:16 pm - 10:20 am

PTY

CLT

20h 04m

1 stop

9:55 pm - 12:24 pm

CLT

PTY

15h 29m

1 stop

$570American Airlines

Thu, Sep 10 - Mon, Sep 14

1:16 pm - 10:20 am

PTY

CLT

20h 04m

1 stop

9:55 pm - 12:24 pm

CLT

PTY

15h 29m

1 stop

$572American Airlines

Thu, Sep 10 - Mon, Sep 14

1:16 pm - 6:23 am

PTY

CLT

16h 07m

2 stops

9:55 pm - 12:24 pm

CLT

PTY

15h 29m

1 stop

$574American Airlines

Thu, Sep 10 - Mon, Sep 14

7:50 pm - 10:31 am

PTY

CHS

14h 41m

2 stops

10:10 am - 2:55 pm

CHS

PTY

28h 45m

3 stops

$1,097Multiple Airlines

Sun, Dec 27 - Wed, Jan 13

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American Airlines flights from Panama City to South Carolina

Our best American Airlines deals on Panama City to South Carolina flight tickets

American Airlines

Sep 10

PTY1:16 pmPanama City Tocumen Intl

20h 04m

1 stop

CLT10:20 amCharlotte Douglas

Sep 14

CLT9:55 pmCharlotte Douglas

15h 31m

1 stop

PTY12:26 pmPanama City Tocumen Intl

$569

American Airlines

Sep 10

PTY1:16 pmPanama City Tocumen Intl

20h 04m

1 stop

CLT10:20 amCharlotte Douglas

Sep 14

CLT9:55 pmCharlotte Douglas

15h 29m

1 stop

PTY12:24 pmPanama City Tocumen Intl

$570

American Airlines

Sep 10

PTY1:16 pmPanama City Tocumen Intl

20h 04m

1 stop

CLT10:20 amCharlotte Douglas

Sep 14

CLT9:55 pmCharlotte Douglas

15h 29m

1 stop

PTY12:24 pmPanama City Tocumen Intl

$572

Copa Airlines flights from Panama City to South Carolina

Our best Copa Airlines deals on Panama City to South Carolina flight tickets

Copa Airlines

Sep 26

PTY6:41 pmPanama City Tocumen Intl

14h 03m

1 stop

CLT9:44 amCharlotte Douglas

Oct 16

CLT6:00 amCharlotte Douglas

8h 31m

1 stop

PTY1:31 pmPanama City Tocumen Intl

$560

Copa Airlines

Oct 30

PTY6:46 pmPanama City Tocumen Intl

23h 00m

1 stop

CLT6:46 pmCharlotte Douglas

Nov 3

CLT6:00 amCharlotte Douglas

7h 31m

1 stop

PTY1:31 pmPanama City Tocumen Intl

$567

Copa Airlines

Jul 16

PTY8:10 amPanama City Tocumen Intl

12h 06m

1 stop

CAE9:16 pmColumbia Metropolitan

Jul 21

CAE7:45 pmColumbia Metropolitan

11h 28m

1 stop

PTY6:13 amPanama City Tocumen Intl

$1,327

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 9/2

2:20 pm-11:57 pm

1 stop8h 37m

Charlotte Douglas

Wed 9/16

6:40 am-12:58 pm

1 stop7h 18m

$551

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sat 9/26

6:41 pm-9:44 am

1 stop14h 03m

Charlotte Douglas

Fri 10/16

6:00 am-1:31 pm

1 stop8h 31m

$560

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 12/21

4:41 pm-9:54 pm

1 stop29h 13m

Charleston

Thu 1/21

6:05 am-7:38 pm

2 stops13h 33m

$562

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/24

9:45 am-10:08 am

2 stops23h 23m

Charlotte Douglas

Mon 9/28

7:00 am-7:31 pm

1 stop13h 31m

$564

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 7/23

5:30 am-5:12 pm

2 stops10h 42m

Charlotte Douglas

Wed 7/29

6:48 pm-1:55 am

3 stops32h 07m

$567

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

1:16 pm-10:20 am

1 stop20h 04m

Charlotte Douglas

Mon 9/14

9:55 pm-12:26 pm

1 stop15h 31m

$569

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

1:16 pm-10:20 am

1 stop20h 04m

Charlotte Douglas

Mon 9/14

9:55 pm-12:24 pm

1 stop15h 29m

$570

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

1:16 pm-10:20 am

1 stop20h 04m

Charlotte Douglas

Mon 9/14

9:55 pm-12:24 pm

1 stop15h 29m

$572

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

1:16 pm-6:23 am

2 stops16h 07m

Charlotte Douglas

Mon 9/14

9:55 pm-12:24 pm

1 stop15h 29m

$574

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 12/27

7:50 pm-10:31 am

2 stops14h 41m

Charleston

Wed 1/13

10:10 am-2:55 pm

3 stops28h 45m

$1,097

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Panama City is in December. Flight prices, which tend to average around $148, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to South Carolina from Panama City during February instead. Flights to South Carolina in February, while not as cheap as those in December, still average around $158.

Can stopping save me money on Panama City to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Panama City to South Carolina flight.

Cheap Panama City to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to South Carolina

Fastest flight time	11h 16m
Direct flights	None

The fastest flight from Panama City to South Carolina takes 11h 16m

There are no direct flights from Panama City to South Carolina. There are no popular flight routes from Panama City to South Carolina.

Search flight deals

Frequently asked questions about flying from Panama City to South Carolina

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to South Carolina?
Prices for flights from Panama City Tocumen Intl Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to South Carolina?
The number of operators available for flights from Panama City Tocumen Intl Airport to South Carolina is 2 as of July 2026.
How old do you have to be to fly from Panama City Tocumen Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama City to South Carolina

Compare and see reviews for airlines that fly from Panama City to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $397	Free Cancellation	Rating 7.1 11,810 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to South Carolina for you.

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

All flight searches from Panama City to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South Carolina from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.