What is the cheapest airline that flies from Panama City Tocumen Intl to South Carolina?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Panama City Tocumen Intl to South Carolina

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to South Carolina?

Prices for flights from Panama City Tocumen Intl Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to South Carolina?

The number of operators available for flights from Panama City Tocumen Intl Airport to South Carolina is 3 as of April 2026.

How old do you have to be to fly from Panama City Tocumen Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$222 Cheap Flights from Panama City to South Carolina in 2026

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Find the cheapest flights from Panama City to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:10 pm - 11:45 am

PTY

CLT

19h 35m

2 stops

6:30 am - 9:15 am

CLT

PTY

27h 45m

2 stops

$431Multiple Airlines

mer, apr 15 - dom, apr 19

10:10 am - 11:45 am

PTY

CLT

24h 35m

2 stops

6:30 am - 10:30 am

CLT

PTY

29h 00m

3 stops

$446Multiple Airlines

mer, apr 15 - dom, apr 19

2:21 pm - 11:57 pm

PTY

CLT

8h 36m

1 stop

6:45 am - 12:56 pm

CLT

PTY

7h 11m

1 stop

$465Delta

gio, set 10 - lun, set 14

2:15 pm - 10:56 pm

PTY

CHS

7h 41m

1 stop

6:15 am - 1:09 pm

CHS

PTY

7h 54m

1 stop

$476Delta

lun, giu 1 - mar, giu 16

3:40 pm - 6:27 am

PTY

CLT

13h 47m

2 stops

9:00 pm - 2:10 pm

CLT

PTY

18h 10m

1 stop

$477American Airlines

gio, set 10 - lun, set 14

3:40 pm - 6:27 am

PTY

CLT

13h 47m

2 stops

8:15 pm - 2:10 pm

CLT

PTY

18h 55m

1 stop

$478American Airlines

gio, set 10 - lun, set 14

3:40 pm - 6:27 am

PTY

CLT

13h 47m

2 stops

8:15 pm - 2:10 pm

CLT

PTY

18h 55m

1 stop

$479American Airlines

gio, set 10 - lun, set 14

7:55 am - 10:15 pm

PTY

CHS

13h 20m

1 stop

6:50 am - 2:14 pm

CHS

PTY

8h 24m

1 stop

$495United Airlines

lun, giu 1 - mar, giu 16

7:55 am - 10:08 am

PTY

CHS

25h 13m

2 stops

10:00 am - 7:31 pm

CHS

PTY

10h 31m

2 stops

$509United Airlines

mer, mag 27 - mer, giu 3

2:15 pm - 11:58 pm

PTY

MYR

8h 43m

1 stop

7:00 am - 12:59 pm

MYR

PTY

6h 59m

1 stop

$699JetBlue

ven, giu 5 - sab, giu 20

American Airlines flights from Panama City to South Carolina

Our best American Airlines deals on Panama City to South Carolina flight tickets

American Airlines

Sep 10

PTY3:40 pmPanama City Tocumen Intl

13h 47m

2 stops

CLT6:27 amCharlotte Douglas

Sep 14

CLT9:00 pmCharlotte Douglas

18h 10m

1 stop

PTY2:10 pmPanama City Tocumen Intl

$477

American Airlines

Sep 10

PTY3:40 pmPanama City Tocumen Intl

13h 47m

2 stops

CLT6:27 amCharlotte Douglas

Sep 14

CLT8:15 pmCharlotte Douglas

18h 55m

1 stop

PTY2:10 pmPanama City Tocumen Intl

$478

American Airlines

Sep 10

PTY3:40 pmPanama City Tocumen Intl

13h 47m

2 stops

CLT6:27 amCharlotte Douglas

Sep 14

CLT8:15 pmCharlotte Douglas

18h 55m

1 stop

PTY2:10 pmPanama City Tocumen Intl

$479

United Airlines flights from Panama City to South Carolina

Our best United Airlines deals on Panama City to South Carolina flight tickets

United Airlines

Jun 1

PTY7:55 amPanama City Tocumen Intl

25h 13m

2 stops

CHS10:08 amCharleston

Jun 16

CHS6:50 amCharleston

12h 47m

1 stop

PTY6:37 pmPanama City Tocumen Intl

$495

United Airlines

May 27

PTY7:55 amPanama City Tocumen Intl

25h 13m

2 stops

CHS10:08 amCharleston

Jun 3

CHS10:00 amCharleston

10h 31m

2 stops

PTY7:31 pmPanama City Tocumen Intl

$509

United Airlines

Jun 5

PTY3:30 pmPanama City Tocumen Intl

17h 38m

2 stops

CHS10:08 amCharleston

Jun 15

CHS6:50 amCharleston

8h 24m

1 stop

PTY2:14 pmPanama City Tocumen Intl

$515

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mer 4/15

3:10 pm-11:45 am

2 stops19h 35m

Charlotte Douglas

dom 4/19

6:30 am-9:15 am

2 stops27h 45m

$431

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mer 4/15

10:10 am-11:45 am

2 stops24h 35m

Charlotte Douglas

dom 4/19

6:30 am-10:30 am

3 stops29h 00m

$446

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

gio 9/10

2:21 pm-11:57 pm

1 stop8h 36m

Charlotte Douglas

lun 9/14

6:45 am-12:56 pm

1 stop7h 11m

$465

Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

lun 6/1

2:15 pm-10:56 pm

1 stop7h 41m

Charleston

mar 6/16

6:15 am-1:09 pm

1 stop7h 54m

$476

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

gio 9/10

3:40 pm-6:27 am

2 stops13h 47m

Charlotte Douglas

lun 9/14

9:00 pm-2:10 pm

1 stop18h 10m

$477

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

gio 9/10

3:40 pm-6:27 am

2 stops13h 47m

Charlotte Douglas

lun 9/14

8:15 pm-2:10 pm

1 stop18h 55m

$478

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

gio 9/10

3:40 pm-6:27 am

2 stops13h 47m

Charlotte Douglas

lun 9/14

8:15 pm-2:10 pm

1 stop18h 55m

$479

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

lun 6/1

7:55 am-10:15 pm

1 stop13h 20m

Charleston

mar 6/16

6:50 am-2:14 pm

1 stop8h 24m

$495

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

mer 5/27

7:55 am-10:08 am

2 stops25h 13m

Charleston

mer 6/3

10:00 am-7:31 pm

2 stops10h 31m

$509

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

ven 6/5

2:15 pm-11:58 pm

1 stop8h 43m

Myrtle Beach Intl

sab 6/20

7:00 am-12:59 pm

1 stop6h 59m

$699

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Panama City is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to South Carolina from Panama City during August instead. Flights to South Carolina in August, while not as cheap as those in December, still average around $395.

Can stopping save me money on Panama City to South Carolina flights?

You could potentially save up to 15% on your flight if you consider stops on a Panama City to South Carolina flight.

Cheap Panama City to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to South Carolina

Fastest flight time	7h 41m
Direct flights	None

The fastest flight from Panama City to South Carolina takes 7h 41m

There are no direct flights from Panama City to South Carolina. There are no popular flight routes from Panama City to South Carolina.

Search flight deals

Frequently asked questions about flying from Panama City to South Carolina

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to South Carolina?
Prices for flights from Panama City Tocumen Intl Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to South Carolina?
The number of operators available for flights from Panama City Tocumen Intl Airport to South Carolina is 3 as of April 2026.
How old do you have to be to fly from Panama City Tocumen Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to South Carolina for you.

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

All flight searches from Panama City to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South Carolina from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.