Cheap flights from Panama City to Chicago from $316
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 9/14
5:30 am-5:52 am
3 stops24h 22m
Chicago O'Hare Intl
Sun 9/20
1:40 am-1:55 am
3 stops24h 15m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 8/31
4:25 am-9:20 pm
1 stop16h 55m
Chicago O'Hare Intl
Mon 9/14
11:20 pm-2:15 pm
1 stop14h 55m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Fri 10/23
4:25 am-9:20 pm
1 stop16h 55m
Chicago O'Hare Intl
Sat 11/7
10:20 pm-4:55 pm
1 stop17h 35m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sat 10/24
4:25 am-9:20 pm
1 stop16h 55m
Chicago O'Hare Intl
Thu 11/5
10:20 pm-8:50 am
1 stop9h 30m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Tue 9/1
10:10 am-9:20 pm
1 stop11h 10m
Chicago O'Hare Intl
Sat 9/5
11:20 pm-2:15 pm
1 stop14h 55m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sun 9/20
4:25 am-9:20 pm
1 stop16h 55m
Chicago O'Hare Intl
Thu 10/1
11:20 pm-9:15 am
1 stop9h 55m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Tue 9/15
5:55 pm-5:52 am
3 stops35h 57m
Chicago O'Hare Intl
Mon 9/21
1:40 am-1:55 am
3 stops24h 15m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 9/14
8:11 am-5:52 am
2 stops21h 41m
Chicago O'Hare Intl
Mon 9/21
7:11 am-8:19 pm
1 stop13h 08m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Thu 12/24
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Thu 12/31
2:13 pm-8:37 pm
Nonstop5h 24m
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sat 11/21
8:05 am-12:46 pm
Nonstop5h 41m
Chicago O'Hare Intl
Fri 12/4
7:35 am-2:00 pm
Nonstop5h 25m
See travel insights to Chicago from
How to get the cheapest flight ticket from Panama City to Chicago
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Panama City and Chicago?
Prices are currently typical for flights on this route.
Typical prices usually range from $649 to $789.The lowest price recently found on this route was $668.
What is the cheapest month to fly to Chicago?
The month of November is, on average, the cheapest month to fly to Chicago from Panama City, with most prices found around $550. If you’re not able to fly to Chicago in November, then September is your next best option. Flight prices from Panama City to Chicago during September average around $572.
What is the cheapest day to depart on your flight to Chicago?
The cheapest day to depart on your flight to Chicago is on a Saturday when prices can be found for as low as $465. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Panama City to Chicago for around $887.
What is the cheapest time of day to depart on your flight to Chicago?
Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Panama City to Chicago during this time can be as low as $616. In contrast, the most expensive time of day to depart to Chicago is in the morning when prices are around $792.
What is the cheapest Panama City Tocumen Intl to Chicago flight route?
Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago flight prices
How far in advance should I book a flight from Panama City to Chicago?
You are more likely to see cheaper flights to Chicago from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $680 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Panama City for as low as $510 on momondo.
What cabin class options are available on Panama City to Chicago flights?
There are 3 cabin classes available to choose from on Panama City to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on Panama City to Chicago flights?
You could potentially save up to 49% on your flight if you consider stops on a Panama City to Chicago flight.
How have Panama City to Chicago flight prices changed over time?
As of August 2026, prices for Panama City to Chicago flights are approximately 22% cheaper when compared to flights at the same time last year.
How many flights depart from Panama City to Chicago on average per day?
As of August 2026, there are 4 flights per day flying from Panama City to Chicago. The most common time of day flights depart is 8:00AM, with 52% of flights taking off at noon.
How many flights depart from Panama City to Chicago on average per week?
As of August 2026, there are 30 flights per week flying from Panama City to Chicago. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.
When to book flights from Panama City to Chicago
Cheap Panama City to Chicago (PTY to CHI) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago
Frequently asked questions about flying from Panama City to Chicago
How far is Panama City Tocumen Intl to Chicago by plane?
Panama City Tocumen Intl and Chicago are 2323.9 mi apart from one another. Typically, this will take 5h 37m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?
Prices for flights from Panama City Tocumen Intl Airport to Chicago refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?
As of August 2026, there is 1 operator available to choose from for flights from Panama City Tocumen Intl Airport to Chicago.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading plane model is Boeing 737-800, making up 41.41% of the total bookings. Other popular models include Boeing 737 MAX 9 with 31.31%, Boeing 737 MAX 8 with 20.20%, and Boeing 737-900 with 3.03%.
What is the most popular airline from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading airline is Copa Airlines, making up 100% of the total bookings.
Best airlines flying from Panama City to Chicago
Compare and see reviews for airlines that fly from Panama City to Chicago with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $417 | Free Cancellation | Rating 7.6 1,566 reviews |
Copa Airlines Flights From Panama City to Chicago
Copa Airlines flight deals from Panama City to Chicago start from $417 round-trip. Over the 12 Copa Airlines flights for this route in a normal week, average airfare is usually $733 round-trip - but some users have found much cheaper deals with momondo.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Panama City to Chicago?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from Panama City to Chicago with flexible booking policies on momondo?
Flights from Panama City to Chicago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from Panama City to Chicago?
Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to Chicago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.