Which airport is the most popular layover for flights between Panama City and Chicago?

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Panama City Tocumen Intl to Chicago?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Chicago

Which layover airport offers the lowest fares from Panama City to Chicago?

Flights via Bogotá (BOG) offer the lowest average round-trip price of $430.

How many flights depart from Panama City to Chicago on average per week?

As of August 2025, there are 32 flights per week flying from Panama City to Chicago. The most common day of the week flights depart is Wed, with 25% of flights taking off on this day.

Which layover airport has the shortest travel time from Panama City to Chicago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 9h 37m.

Which layover airport has the shortest connection time from Panama City to Chicago?

Bogotá (BOG) has the shortest average layover time for this route: 1h 58m.

How many flights depart from Panama City to Chicago on average per day?

As of August 2025, there are 4 flights per day flying from Panama City to Chicago. The most common time of day flights depart is 6:00PM, with 57% of flights taking off in the evening.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?

Prices for flights from Panama City Tocumen Intl Airport to Chicago refresh daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?

As of August 2025, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Chicago.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago.

What documentation or ID do you need to fly to Chicago?

The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$247 Cheap Flights from Panama City to Chicago in 2025

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Find the cheapest flights from Panama City to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

5:25 pm - 10:48 pmPTY-ORD

29h 23m2 stops

5:05 am - 8:55 amORD-PTY

27h 50m2 stops

$412

Find Deal

Fri, Sep 26 - Wed, Oct 1

3:20 am - 10:48 pmPTY-ORD

19h 28m2 stops

5:05 am - 12:45 amORD-PTY

19h 40m2 stops

$413

Find Deal

Thu, Sep 25 - Wed, Oct 1

9:33 pm - 9:18 amPTY-ORD

11h 45m1 stop

10:27 am - 7:29 pmORD-PTY

9h 02m1 stop

$443

Find Deal

Wed, Sep 24 - Sun, Sep 28

3:25 am - 1:15 pmPTY-ORD

9h 50m1 stop

2:35 pm - 10:10 amORD-PTY

19h 35m1 stop

$489Avianca

Find Deal

Fri, Sep 12 - Sat, Sep 20

2:55 am - 9:20 pmPTY-ORD

18h 25m1 stop

10:20 pm - 4:55 pmORD-PTY

17h 35m1 stop

$490Avianca

Find Deal

Fri, Oct 31 - Thu, Nov 6

3:25 am - 1:15 pmPTY-ORD

33h 50m1 stop

10:20 pm - 4:55 pmORD-PTY

17h 35m1 stop

$495Avianca

Find Deal

Mon, Sep 8 - Mon, Nov 10

2:55 am - 9:20 pmPTY-ORD

18h 25m1 stop

11:20 pm - 4:55 pmORD-PTY

17h 35m1 stop

$496Avianca

Find Deal

Sun, Oct 26 - Fri, Oct 31

3:21 pm - 10:14 pmPTY-MDW

7h 53m1 stop

6:00 am - 2:12 pmMDW-PTY

7h 12m1 stop

$598Delta

Find Deal

Wed, Nov 5 - Wed, Nov 19

2:10 pm - 8:40 amPTY-MDW

18h 30m2 stops

6:00 am - 12:56 pmMDW-PTY

6h 56m1 stop

$633Delta

Find Deal

Fri, Oct 3 - Tue, Oct 7

2:21 pm - 10:14 pmPTY-MDW

7h 53m1 stop

6:00 am - 12:56 pmMDW-PTY

6h 56m1 stop

$635Delta

Find Deal

Mon, Oct 20 - Sat, Oct 25

Avianca flights from Panama City to Chicago

Our best Avianca deals on Panama City to Chicago flight tickets

Avianca

Sep 12

PTY3:25 amPanama City Tocumen Intl

9h 50m

1 stop

ORD1:15 pmChicago O'Hare Intl

Sep 20

ORD2:35 pmChicago O'Hare Intl

19h 35m

1 stop

PTY10:10 amPanama City Tocumen Intl

$489

Find similar

Avianca

Oct 31

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD9:20 pmChicago O'Hare Intl

Nov 6

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$490

Find similar

Avianca

Sep 8

PTY3:25 amPanama City Tocumen Intl

33h 50m

1 stop

ORD1:15 pmChicago O'Hare Intl

Nov 10

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$495

Find similar

Delta flights from Panama City to Chicago

Our best Delta deals on Panama City to Chicago flight tickets

Delta

Nov 5

PTY3:21 pmPanama City Tocumen Intl

7h 53m

1 stop

MDW10:14 pmChicago Midway

Nov 19

MDW6:00 amChicago Midway

7h 12m

1 stop

PTY2:12 pmPanama City Tocumen Intl

$598

Find similar

Delta

Oct 3

PTY2:10 pmPanama City Tocumen Intl

18h 30m

2 stops

MDW8:40 amChicago Midway

Oct 7

MDW6:00 amChicago Midway

6h 56m

1 stop

PTY12:56 pmPanama City Tocumen Intl

$633

Find similar

Delta

Oct 20

PTY2:21 pmPanama City Tocumen Intl

7h 53m

1 stop

MDW10:14 pmChicago Midway

Oct 25

MDW6:00 amChicago Midway

6h 56m

1 stop

PTY12:56 pmPanama City Tocumen Intl

$635

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 9/26

5:25 pm-10:48 pm

2 stops29h 23m

Chicago O'Hare Intl

Wed 10/1

5:05 am-8:55 am

2 stops27h 50m

$412

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 9/25

3:20 am-10:48 pm

2 stops19h 28m

Chicago O'Hare Intl

Wed 10/1

5:05 am-12:45 am

2 stops19h 40m

$413

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/24

9:33 pm-9:18 am

1 stop11h 45m

Chicago O'Hare Intl

Sun 9/28

10:27 am-7:29 pm

1 stop9h 02m

$443

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 9/12

3:25 am-1:15 pm

1 stop9h 50m

Chicago O'Hare Intl

Sat 9/20

2:35 pm-10:10 am

1 stop19h 35m

$489

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/31

2:55 am-9:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-4:55 pm

1 stop17h 35m

$490

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 9/8

3:25 am-1:15 pm

1 stop33h 50m

Chicago O'Hare Intl

Mon 11/10

10:20 pm-4:55 pm

1 stop17h 35m

$495

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 10/26

2:55 am-9:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Fri 10/31

11:20 pm-4:55 pm

1 stop17h 35m

$496

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 11/5

3:21 pm-10:14 pm

1 stop7h 53m

Chicago Midway

Wed 11/19

6:00 am-2:12 pm

1 stop7h 12m

$598

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 10/3

2:10 pm-8:40 am

2 stops18h 30m

Chicago Midway

Tue 10/7

6:00 am-12:56 pm

1 stop6h 56m

$633

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Mon 10/20

2:21 pm-10:14 pm

1 stop7h 53m

Chicago Midway

Sat 10/25

6:00 am-12:56 pm

1 stop6h 56m

$635

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to Chicago?

The month of July is, on average, the cheapest month to fly to Chicago from Panama City, with most prices found around $423. If you’re not able to fly to Chicago in July, then April is your next best option. Flight prices from Panama City to Chicago during April average around $479.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Wednesday when prices can be found for as low as $494. This is often the case because there is less demand to fly during this day of the week. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Panama City to Chicago for around $1,166.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Panama City to Chicago during this time can be as low as $550. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $1,152.

What is the cheapest Panama City Tocumen Intl to Chicago flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $575 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Panama City for as low as $478 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Chicago flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Chicago flight prices changed over time?

As of August 2025, prices for Panama City to Chicago flights are approximately 55% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Chicago (PTY to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago

Best Price Found	$722
Fastest flight time	5h 36m
Direct flights	Every day
Airports in Chicago	1 airport

The best one-way flight to Chicago from Panama City in the past 72 hours is $722. The best round-trip flight deal from Panama City to Chicago found on momondo in the last 72 hours is $465.

The fastest flight from Panama City to Chicago takes 5h 36m

Direct flights go from Panama City to Chicago every day.

There is 1 airport near Chicago: Chicago O'Hare Intl (ORD)

Search flight deals

How far is Panama City Tocumen Intl to Chicago by plane?
Panama City Tocumen Intl and Chicago are 2323.9 mi apart from one another. Typically, this will take 7h 53m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?
Prices for flights from Panama City Tocumen Intl Airport to Chicago refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?
As of August 2025, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Chicago.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading plane model is Boeing 737-800, making up 89.43% of the total bookings. Other popular models include Boeing 737 MAX 9 with 3.25%, Boeing 787-9 Dreamliner with 1.63%, and Boeing 737-900 with 1.63%.
What is the most popular airline from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading airline is Copa Airlines, making up 79% of the total bookings. Other popular airlines include Avianca with 21%.

Best airlines flying from Panama City to Chicago

Compare and see reviews for airlines that fly from Panama City to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $415	Free Cancellation	Rating 7.5 1,517 reviews		Search Copa Airlines flights
Delta	PriceFrom $569	Free Cancellation	Rating 7.9 7,977 reviews		Search Delta flights

Copa Airlines Flights From Panama City to Chicago
Copa Airlines flight deals from Panama City to Chicago start from $415 round-trip. Over the 13 Copa Airlines flights for this route in a normal week, average airfare is usually $549 round-trip - but some users have found much cheaper deals with momondo.

Merrillville

New Buffalo

Hammond

Benton Harbor

Saint Joseph

Lansing

Portage

Schererville

Valparaiso

Crown Point

Munster

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Flights from Panama City to Chicago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to the United States

Cheap flights from Panama City to Chicago from $247

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 9/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Avianca flights from Panama City to Chicago

Our best Avianca deals on Panama City to Chicago flight tickets

Delta flights from Panama City to Chicago

Our best Delta deals on Panama City to Chicago flight tickets

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Use the filters below to find and compare flights from Panama City to Chicago that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of July is, on average, the cheapest month to fly to Chicago from Panama City, with most prices found around $423. If you’re not able to fly to Chicago in July, then April is your next best option. Flight prices from Panama City to Chicago during April average around $479.

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Panama City to Chicago during this time can be as low as $550. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $1,152.

What is the cheapest Panama City Tocumen Intl to Chicago flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on Panama City Tocumen Intl to Chicago flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Chicago flight prices changed over time?

As of August 2025, prices for Panama City to Chicago flights are approximately 55% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Chicago?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Chicago

Which airport is the most popular layover for flights between Panama City and Chicago?

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Panama City to Chicago?

Flights via Bogotá (BOG) offer the lowest average round-trip price of $430.

Which layover airport has the shortest travel time from Panama City to Chicago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 9h 37m.

Which layover airport has the shortest connection time from Panama City to Chicago?

Bogotá (BOG) has the shortest average layover time for this route: 1h 58m.

How many flights depart from Panama City to Chicago on average per day?

As of August 2025, there are 4 flights per day flying from Panama City to Chicago. The most common time of day flights depart is 6:00PM, with 57% of flights taking off in the evening.

How many flights depart from Panama City to Chicago on average per week?

As of August 2025, there are 32 flights per week flying from Panama City to Chicago. The most common day of the week flights depart is Wed, with 25% of flights taking off on this day.

When to book flights from Panama City to Chicago

Cheap Panama City to Chicago (PTY to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

How far is Panama City Tocumen Intl to Chicago by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from Panama City to Chicago?

What is the most popular airline from Panama City to Chicago?

Best airlines flying from Panama City to Chicago

Compare and see reviews for airlines that fly from Panama City to Chicago with momondo

Copa Airlines Flights From Panama City to Chicago

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Chicago?

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago