What is the cheapest airline that flies from Panama City Tocumen Intl to Chicago?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Chicago

How many flights depart from Panama City to Chicago on average per day?

As of February 2026, there are 3 flights per day flying from Panama City to Chicago. The most common time of day flights depart is 8:00AM, with 60% of flights taking off at noon.

How many flights depart from Panama City to Chicago on average per week?

As of February 2026, there are 26 flights per week flying from Panama City to Chicago. The most common day of the week flights depart is Mon, with 19% of flights taking off on this day.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?

Prices for flights from Panama City Tocumen Intl Airport to Chicago refresh daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?

As of February 2026, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Chicago.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago.

What documentation or ID do you need to fly to Chicago?

The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$176 Cheap Flights from Panama City to Chicago in 2026

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Find the cheapest flights from Panama City to Chicago

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

2:55 am - 8:20 pm

PTY

ORD

18h 25m

1 stop

10:20 pm - 4:55 pm

ORD

PTY

17h 35m

1 stop

$289Avianca

Wed, Feb 25 - Wed, Mar 4

9:45 am - 8:20 pm

PTY

ORD

11h 35m

1 stop

10:20 pm - 2:00 pm

ORD

PTY

14h 40m

1 stop

$291Avianca

Thu, Feb 12 - Tue, Feb 17

9:45 am - 8:20 pm

PTY

ORD

11h 35m

1 stop

7:23 pm - 8:50 am

ORD

PTY

12h 27m

2 stops

$368Multiple Airlines

Thu, Feb 26 - Wed, Mar 4

9:45 am - 9:20 pm

PTY

ORD

11h 35m

1 stop

4:51 pm - 8:50 am

ORD

PTY

15h 59m

2 stops

$378Multiple Airlines

Tue, Mar 17 - Tue, Mar 24

7:50 pm - 6:31 pm

PTY

ORD

22h 41m

3 stops

11:20 pm - 2:00 pm

ORD

PTY

14h 40m

1 stop

$392Multiple Airlines

Tue, Mar 17 - Tue, Mar 24

9:45 am - 8:20 pm

PTY

ORD

11h 35m

1 stop

9:18 am - 8:50 am

ORD

PTY

22h 32m

2 stops

$396Multiple Airlines

Thu, Feb 12 - Tue, Feb 17

5:50 pm - 9:39 am

PTY

ORD

16h 49m

2 stops

11:20 pm - 8:50 am

ORD

PTY

9h 30m

1 stop

$398Multiple Airlines

Wed, Mar 4 - Wed, Mar 11

2:27 pm - 10:28 pm

PTY

MDW

8h 01m

1 stop

6:00 am - 12:55 pm

MDW

PTY

6h 55m

1 stop

$660Delta

Wed, May 6 - Sat, May 9

3:15 pm - 10:31 pm

PTY

MDW

8h 16m

1 stop

6:00 am - 1:02 pm

MDW

PTY

7h 02m

1 stop

$690Delta

Sat, Feb 14 - Sat, Apr 25

2:28 pm - 9:56 am

PTY

MDW

19h 28m

1 stop

10:45 am - 1:03 pm

MDW

PTY

26h 18m

1 stop

$691LATAM Airlines

Wed, Apr 1 - Fri, Apr 10

Avianca flights from Panama City to Chicago

Our best Avianca deals on Panama City to Chicago flight tickets

Avianca

Feb 25

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

Mar 4

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$289

Avianca

Feb 12

PTY9:45 amPanama City Tocumen Intl

11h 35m

1 stop

ORD8:20 pmChicago O'Hare Intl

Feb 17

ORD10:20 pmChicago O'Hare Intl

14h 40m

1 stop

PTY2:00 pmPanama City Tocumen Intl

$291

Avianca

Feb 9

PTY9:45 amPanama City Tocumen Intl

11h 35m

1 stop

ORD8:20 pmChicago O'Hare Intl

Feb 17

ORD10:20 pmChicago O'Hare Intl

9h 30m

1 stop

PTY8:50 amPanama City Tocumen Intl

$303

Copa Airlines flights from Panama City to Chicago

Our best Copa Airlines deals on Panama City to Chicago flight tickets

Copa Airlines

Feb 14

PTY7:20 pmPanama City Tocumen Intl

5h 44m

ORD12:04 amChicago O'Hare Intl

Apr 25

ORD3:21 pmChicago O'Hare Intl

5h 20m

PTY8:41 pmPanama City Tocumen Intl

$684

Copa Airlines

Feb 10

PTY7:55 amPanama City Tocumen Intl

5h 36m

ORD12:31 pmChicago O'Hare Intl

Feb 26

ORD2:22 pmChicago O'Hare Intl

5h 13m

PTY8:35 pmPanama City Tocumen Intl

$718

Copa Airlines

Feb 9

PTY7:55 amPanama City Tocumen Intl

5h 36m

ORD12:31 pmChicago O'Hare Intl

Feb 17

ORD7:34 amChicago O'Hare Intl

5h 26m

PTY2:00 pmPanama City Tocumen Intl

$1,235

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 2/25

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Wed 3/4

10:20 pm-4:55 pm

1 stop17h 35m

$289

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 2/12

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Tue 2/17

10:20 pm-2:00 pm

1 stop14h 40m

$291

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 2/26

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Wed 3/4

7:23 pm-8:50 am

2 stops12h 27m

$368

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 3/17

9:45 am-9:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Tue 3/24

4:51 pm-8:50 am

2 stops15h 59m

$378

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 3/17

7:50 pm-6:31 pm

3 stops22h 41m

Chicago O'Hare Intl

Tue 3/24

11:20 pm-2:00 pm

1 stop14h 40m

$392

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 2/12

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Tue 2/17

9:18 am-8:50 am

2 stops22h 32m

$396

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 3/4

5:50 pm-9:39 am

2 stops16h 49m

Chicago O'Hare Intl

Wed 3/11

11:20 pm-8:50 am

1 stop9h 30m

$398

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 5/6

2:27 pm-10:28 pm

1 stop8h 01m

Chicago Midway

Sat 5/9

6:00 am-12:55 pm

1 stop6h 55m

$660

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sat 2/14

3:15 pm-10:31 pm

1 stop8h 16m

Chicago Midway

Sat 4/25

6:00 am-1:02 pm

1 stop7h 02m

$690

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 4/1

2:28 pm-9:56 am

1 stop19h 28m

Chicago Midway

Fri 4/10

10:45 am-1:03 pm

1 stop26h 18m

$691

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago?

The month of July is, on average, the cheapest month to fly to Chicago from Panama City, with most prices found around $405. If you’re not able to fly to Chicago in July, then April is your next best option. Flight prices from Panama City to Chicago during April average around $411.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Wednesday when prices can be found for as low as $479. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Panama City to Chicago for around $917.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Panama City to Chicago during this time can be as low as $532. In contrast, the most expensive time of day to depart to Chicago is in the morning when prices are around $711.

What is the cheapest Panama City Tocumen Intl to Chicago flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $567 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Panama City for as low as $463 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Chicago flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago flights?

You could potentially save up to 72% on your flight if you consider stops on a Panama City to Chicago flight.

How have Panama City to Chicago flight prices changed over time?

As of February 2026, prices for Panama City to Chicago flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Chicago (PTY to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago

Best Price Found	$485
Fastest flight time	5h 36m
Direct flights	Every day
Airports in Chicago	3 airports

The best one-way flight to Chicago from Panama City in the past 72 hours is $485. The best round-trip flight deal from Panama City to Chicago found on momondo in the last 72 hours is $887.

The fastest flight from Panama City to Chicago takes 5h 36m

Direct flights go from Panama City to Chicago every day.

There are 3 airports in Chicago. From Panama City there are direct flights to Chicago O'Hare Intl (ORD).

Search flight deals

How far is Panama City Tocumen Intl to Chicago by plane?
Panama City Tocumen Intl and Chicago are 2323.9 mi apart from one another. Typically, this will take 5h 36m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?
Prices for flights from Panama City Tocumen Intl Airport to Chicago refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?
As of February 2026, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Chicago.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading plane model is Boeing 737-800, making up 65.00% of the total bookings. Other popular models include Boeing 737 MAX 8 with 21.00%, Boeing 737 MAX 9 with 7.00%, and Boeing 787-9 Dreamliner with 2.00%.
What is the most popular airline from Panama City to Chicago?
Based on momondo bookings for flights between Panama City and Chicago, the leading airline is Copa Airlines, making up 100% of the total bookings.

Best airlines flying from Panama City to Chicago

Compare and see reviews for airlines that fly from Panama City to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $405	Free Cancellation	Rating 7.5 1,559 reviews		Search Copa Airlines flights
United Airlines	PriceFrom $423	Free Cancellation	Rating 7.4 9,231 reviews		Search United Airlines flights

Copa Airlines Flights From Panama City to Chicago
Copa Airlines flight deals from Panama City to Chicago start from $405 round-trip. Over the 11 Copa Airlines flights for this route in a normal week, average airfare is usually $581 round-trip - but some users have found much cheaper deals with momondo.
United Airlines Flights From Panama City to Chicago
Across 9,231 United Airlines reviews on momondo, the average score is 7.4/10. United Airlines flies from Panama City to Chicago about 11 times each week, with ticket deals ranging from $423 to $485. Price data is based on momondo searches in the last 72 hours.

Merrillville

New Buffalo

Hammond

Benton Harbor

Saint Joseph

Portage

Lansing

Schererville

Valparaiso

Munster

Crown Point

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Flights from Panama City to Chicago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Panama City to Chicago from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 3/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from Panama City to Chicago

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Avianca flights from Panama City to Chicago

Our best Avianca deals on Panama City to Chicago flight tickets

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Our best Copa Airlines deals on Panama City to Chicago flight tickets

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Use the filters below to find and compare flights from Panama City to Chicago that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago

What is the cheapest month to fly to Chicago?

The month of July is, on average, the cheapest month to fly to Chicago from Panama City, with most prices found around $405. If you’re not able to fly to Chicago in July, then April is your next best option. Flight prices from Panama City to Chicago during April average around $411.

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Panama City to Chicago during this time can be as low as $532. In contrast, the most expensive time of day to depart to Chicago is in the morning when prices are around $711.

What is the cheapest Panama City Tocumen Intl to Chicago flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on Panama City Tocumen Intl to Chicago flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago flights?

You could potentially save up to 72% on your flight if you consider stops on a Panama City to Chicago flight.

How have Panama City to Chicago flight prices changed over time?

As of February 2026, prices for Panama City to Chicago flights are approximately 35% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Chicago?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Chicago

How many flights depart from Panama City to Chicago on average per day?

As of February 2026, there are 3 flights per day flying from Panama City to Chicago. The most common time of day flights depart is 8:00AM, with 60% of flights taking off at noon.

How many flights depart from Panama City to Chicago on average per week?

As of February 2026, there are 26 flights per week flying from Panama City to Chicago. The most common day of the week flights depart is Mon, with 19% of flights taking off on this day.

When to book flights from Panama City to Chicago

Cheap Panama City to Chicago (PTY to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

How far is Panama City Tocumen Intl to Chicago by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from Panama City to Chicago?

What is the most popular airline from Panama City to Chicago?

Best airlines flying from Panama City to Chicago

Compare and see reviews for airlines that fly from Panama City to Chicago with momondo

Copa Airlines Flights From Panama City to Chicago

United Airlines Flights From Panama City to Chicago

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Chicago?

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago