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Cheap flights from Panama City, Florida to Louisville from $194

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Louisville departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City, Florida to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:10 pm - 9:59 pm
ECP
-
SDF
7h 49m1 stop
United Airlines Logo
9:15 am - 4:12 pm
SDF
-
ECP
7h 57m1 stop
$325United Airlines
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
1:10 pm - 9:59 pm
ECP
-
SDF
7h 49m1 stop
United Airlines Logo
5:35 am - 4:12 pm
SDF
-
ECP
11h 37m2 stops
$330United Airlines
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
6:30 am - 7:31 pm
ECP
-
SDF
12h 01m2 stops
United Airlines Logo
5:35 am - 4:12 pm
SDF
-
ECP
11h 37m2 stops
$335United Airlines
Sat, Jan 17 - Tue, Jan 20
Southwest Logo
7:15 am - 4:00 pm
ECP
-
SDF
7h 45m1 stop
Southwest Logo
6:25 am - 3:45 pm
SDF
-
ECP
10h 20m2 stops
$357Southwest
Thu, Feb 12 - Sun, Feb 15
Southwest Logo
12:35 pm - 12:05 am
ECP
-
SDF
10h 30m2 stops
Southwest Logo
6:25 am - 3:45 pm
SDF
-
ECP
10h 20m2 stops
$362Southwest
Thu, Feb 12 - Sun, Feb 15
Delta Logo
7:45 am - 1:49 pm
ECP
-
SDF
5h 04m1 stop
Delta Logo
9:25 am - 12:38 pm
SDF
-
ECP
4h 13m1 stop
$367Delta
Fri, Jun 19 - Tue, Jun 23
Delta Logo
3:45 pm - 8:56 pm
ECP
-
SDF
4h 11m1 stop
Delta Logo
5:35 am - 8:39 am
SDF
-
ECP
4h 04m1 stop
$377Delta
Fri, Jan 23 - Fri, Jan 30
American Airlines Logo
12:03 pm - 11:19 pm
ECP
-
SDF
10h 16m2 stops
American Airlines Logo
6:00 am - 1:04 pm
SDF
-
ECP
8h 04m1 stop
$382American Airlines
Fri, Jan 23 - Fri, Jan 30
Delta Logo
6:00 am - 11:36 am
ECP
-
SDF
4h 36m1 stop
Delta Logo
5:45 pm - 10:46 pm
SDF
-
ECP
6h 01m1 stop
$386Delta
Tue, Jun 23 - Tue, Jun 23
American Airlines Logo
12:03 pm - 11:19 pm
ECP
-
SDF
10h 16m2 stops
American Airlines Logo
8:07 am - 5:33 pm
SDF
-
ECP
10h 26m2 stops
$387American Airlines
Fri, Jan 23 - Fri, Jan 30

American Airlines flights from Panama City, Florida to Louisville

Our best American Airlines deals on Panama City, Florida to Louisville flight tickets
American Airlines
Jan 23
ECP12:03 pmPanama City NW Florida Beaches
10h 16m
2 stops
SDF11:19 pmLouisville Intl
Jan 30
SDF6:00 amLouisville Intl
8h 04m
1 stop
ECP1:04 pmPanama City NW Florida Beaches
$382
Find similar
American Airlines
Jan 23
ECP12:03 pmPanama City NW Florida Beaches
10h 16m
2 stops
SDF11:19 pmLouisville Intl
Jan 30
SDF8:07 amLouisville Intl
10h 26m
2 stops
ECP5:33 pmPanama City NW Florida Beaches
$387
Find similar

Delta flights from Panama City, Florida to Louisville

Our best Delta deals on Panama City, Florida to Louisville flight tickets
Delta
Jun 19
ECP7:45 amPanama City NW Florida Beaches
5h 04m
1 stop
SDF1:49 pmLouisville Intl
Jun 23
SDF9:25 amLouisville Intl
4h 13m
1 stop
ECP12:38 pmPanama City NW Florida Beaches
$367
Find similar
Delta
Jan 23
ECP3:45 pmPanama City NW Florida Beaches
4h 11m
1 stop
SDF8:56 pmLouisville Intl
Jan 30
SDF5:35 amLouisville Intl
4h 04m
1 stop
ECP8:39 amPanama City NW Florida Beaches
$377
Find similar
Delta
Jun 23
ECP6:00 amPanama City NW Florida Beaches
4h 36m
1 stop
SDF11:36 amLouisville Intl
Jun 23
SDF5:45 pmLouisville Intl
6h 01m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
$386
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sat 1/17

1:10 pm-9:59 pm

1 stop7h 49m

Louisville Intl

Tue 1/20

9:15 am-4:12 pm

1 stop7h 57m

$325

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sat 1/17

1:10 pm-9:59 pm

1 stop7h 49m

Louisville Intl

Tue 1/20

5:35 am-4:12 pm

2 stops11h 37m

$330

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sat 1/17

6:30 am-7:31 pm

2 stops12h 01m

Louisville Intl

Tue 1/20

5:35 am-4:12 pm

2 stops11h 37m

$335

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 2/12

7:15 am-4:00 pm

1 stop7h 45m

Louisville Intl

Sun 2/15

6:25 am-3:45 pm

2 stops10h 20m

$357

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 2/12

12:35 pm-12:05 am

2 stops10h 30m

Louisville Intl

Sun 2/15

6:25 am-3:45 pm

2 stops10h 20m

$362

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 6/19

7:45 am-1:49 pm

1 stop5h 04m

Louisville Intl

Tue 6/23

9:25 am-12:38 pm

1 stop4h 13m

$367

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 1/23

3:45 pm-8:56 pm

1 stop4h 11m

Louisville Intl

Fri 1/30

5:35 am-8:39 am

1 stop4h 04m

$377

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 1/23

12:03 pm-11:19 pm

2 stops10h 16m

Louisville Intl

Fri 1/30

6:00 am-1:04 pm

1 stop8h 04m

$382

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Tue 6/23

6:00 am-11:36 am

1 stop4h 36m

Louisville Intl

Tue 6/23

5:45 pm-10:46 pm

1 stop6h 01m

$386

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 1/23

12:03 pm-11:19 pm

2 stops10h 16m

Louisville Intl

Fri 1/30

8:07 am-5:33 pm

2 stops10h 26m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Panama City, Florida to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of August, then departing from Panama City, Florida during the month June is also very affordable. Most momondo users find prices during this month for around $302.

How have Panama City, Florida to Louisville flight prices changed over time?

As of December 2025, prices for Panama City, Florida to Louisville flights are approximately 52% more expensive when compared to flights at the same time last year.

When to book flights from Panama City, Florida to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Louisville (ECP to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Louisville

Fastest flight time

3h 54m

Direct flights

None
The fastest flight from Panama City, Florida to Louisville takes 3h 54m
There are no direct flights from Panama City, Florida to Louisville. There are no popular flight routes from Panama City, Florida to Louisville.
Search flight deals

  • How far is Panama City NW Florida Beaches to Louisville Intl by plane?

    A flight from Panama City NW Florida Beaches to Louisville Intl will travel around 558.6 mi. In terms of flight time, this usually takes a little over 3h 54m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The necessary travel and health documents for your Louisville Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Louisville?

Best airlines flying from Panama City, Florida to Louisville

Compare and see reviews for airlines that fly from Panama City, Florida to Louisville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,019 reviews
Search Delta flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Charlestown
Brandenburg
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Louisville with flexible booking policies on momondo?

Yes. All flights to Louisville from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Louisville?

momondo helps you find the best flight between Panama City and Louisville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Louisville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Louisville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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