Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City, Florida to Louisville from $166

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Louisville departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City, Florida to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:05 am - 2:00 pm
ECP
-
SDF
5h 55m
1 stop
Delta Logo
6:00 am - 8:40 am
SDF
-
ECP
3h 40m
1 stop
$355Delta
Thu, Mar 26 - Sat, Mar 28
Southwest Logo
7:10 am - 11:40 am
ECP
-
SDF
3h 30m
1 stop
Southwest Logo
5:25 pm - 7:50 pm
SDF
-
ECP
3h 25m
1 stop
$367Southwest
Thu, May 21 - Mon, May 25
Southwest Logo
7:10 am - 11:40 am
ECP
-
SDF
3h 30m
1 stop
Southwest Logo
2:40 pm - 7:50 pm
SDF
-
ECP
6h 10m
2 stops
$372Southwest
Thu, May 21 - Mon, May 25
Delta Logo
7:05 pm - 11:59 pm
ECP
-
SDF
3h 54m
1 stop
Delta Logo
9:25 am - 1:52 pm
SDF
-
ECP
5h 27m
1 stop
$387Delta
Mon, Jul 20 - Fri, Jul 24
Delta Logo
6:00 am - 11:58 am
ECP
-
SDF
4h 58m
1 stop
Delta Logo
5:35 pm - 11:04 pm
SDF
-
ECP
6h 29m
1 stop
$389Delta
Sun, Mar 15 - Wed, Mar 25
Southwest Logo
7:50 am - 12:00 pm
ECP
-
SDF
3h 10m
1 stop
Southwest Logo
6:40 am - 2:15 pm
SDF
-
ECP
8h 35m
2 stops
$402Southwest
Mon, Jul 20 - Fri, Jul 24
United Airlines Logo
6:30 am - 1:36 pm
ECP
-
SDF
6h 06m
1 stop
United Airlines Logo
3:30 pm - 9:59 pm
SDF
-
ECP
7h 29m
1 stop
$403United Airlines
Thu, Apr 9 - Mon, Apr 13
Delta Logo
7:05 am - 11:58 am
ECP
-
SDF
3h 53m
1 stop
Delta Logo
6:00 am - 8:40 am
SDF
-
ECP
3h 40m
1 stop
$413Delta
Sun, Mar 15 - Sat, Mar 28
Delta Logo
6:00 am - 11:58 am
ECP
-
SDF
4h 58m
1 stop
Delta Logo
6:00 am - 8:40 am
SDF
-
ECP
3h 40m
1 stop
$417Delta
Sun, Mar 15 - Sun, Mar 29
American Airlines Logo
3:00 pm - 9:26 pm
ECP
-
SDF
5h 26m
1 stop
American Airlines Logo
6:33 am - 4:04 pm
SDF
-
ECP
10h 31m
2 stops
$422American Airlines
Wed, Mar 18 - Wed, Mar 25

Southwest flights from Panama City, Florida to Louisville

Our best Southwest deals on Panama City, Florida to Louisville flight tickets
Southwest
May 21
ECP7:10 amPanama City NW Florida Beaches
3h 30m
1 stop
SDF11:40 amLouisville Intl
May 25
SDF5:25 pmLouisville Intl
3h 25m
1 stop
ECP7:50 pmPanama City NW Florida Beaches
$367
Southwest
May 21
ECP7:10 amPanama City NW Florida Beaches
3h 30m
1 stop
SDF11:40 amLouisville Intl
May 25
SDF2:40 pmLouisville Intl
6h 10m
2 stops
ECP7:50 pmPanama City NW Florida Beaches
$372
Southwest
Jul 20
ECP7:50 amPanama City NW Florida Beaches
3h 10m
1 stop
SDF12:00 pmLouisville Intl
Jul 24
SDF6:40 amLouisville Intl
8h 35m
2 stops
ECP2:15 pmPanama City NW Florida Beaches
$402

United Airlines flights from Panama City, Florida to Louisville

Our best United Airlines deals on Panama City, Florida to Louisville flight tickets
United Airlines
Apr 9
ECP6:30 amPanama City NW Florida Beaches
6h 06m
1 stop
SDF1:36 pmLouisville Intl
Apr 13
SDF3:30 pmLouisville Intl
7h 29m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
$403
United Airlines
Mar 14
ECP10:24 amPanama City NW Florida Beaches
5h 22m
1 stop
SDF4:46 pmLouisville Intl
Mar 18
SDF6:00 amLouisville Intl
7h 04m
1 stop
ECP12:04 pmPanama City NW Florida Beaches
$447
United Airlines
Mar 17
ECP1:00 pmPanama City NW Florida Beaches
5h 51m
1 stop
SDF7:51 pmLouisville Intl
Mar 25
SDF7:05 amLouisville Intl
10h 07m
2 stops
ECP4:12 pmPanama City NW Florida Beaches
$464

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 3/26

7:05 am-2:00 pm

1 stop5h 55m

Louisville Intl

Sat 3/28

6:00 am-8:40 am

1 stop3h 40m

$355

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 5/21

7:10 am-11:40 am

1 stop3h 30m

Louisville Intl

Mon 5/25

5:25 pm-7:50 pm

1 stop3h 25m

$367

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 5/21

7:10 am-11:40 am

1 stop3h 30m

Louisville Intl

Mon 5/25

2:40 pm-7:50 pm

2 stops6h 10m

$372

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Mon 7/20

7:05 pm-11:59 pm

1 stop3h 54m

Louisville Intl

Fri 7/24

9:25 am-1:52 pm

1 stop5h 27m

$387

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sun 3/15

6:00 am-11:58 am

1 stop4h 58m

Louisville Intl

Wed 3/25

5:35 pm-11:04 pm

1 stop6h 29m

$389

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Mon 7/20

7:50 am-12:00 pm

1 stop3h 10m

Louisville Intl

Fri 7/24

6:40 am-2:15 pm

2 stops8h 35m

$402

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 4/9

6:30 am-1:36 pm

1 stop6h 06m

Louisville Intl

Mon 4/13

3:30 pm-9:59 pm

1 stop7h 29m

$403

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sun 3/15

7:05 am-11:58 am

1 stop3h 53m

Louisville Intl

Sat 3/28

6:00 am-8:40 am

1 stop3h 40m

$413

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sun 3/15

6:00 am-11:58 am

1 stop4h 58m

Louisville Intl

Sun 3/29

6:00 am-8:40 am

1 stop3h 40m

$417

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Wed 3/18

3:00 pm-9:26 pm

1 stop5h 26m

Louisville Intl

Wed 3/25

6:33 am-4:04 pm

2 stops10h 31m

$422

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Louisville from

How to get the cheapest flight ticket from Panama City, Florida to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of August, then departing from Panama City, Florida during the month June is also very affordable. Most momondo users find prices during this month for around $302.

How have Panama City, Florida to Louisville flight prices changed over time?

As of March 2026, prices for Panama City, Florida to Louisville flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Panama City, Florida to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Louisville (ECP to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Louisville

Fastest flight time

3h 30m

Direct flights

None
The fastest flight from Panama City, Florida to Louisville takes 3h 30m
There are no direct flights from Panama City, Florida to Louisville. There are no popular flight routes from Panama City, Florida to Louisville.
Search flight deals

  • How far is Panama City NW Florida Beaches to Louisville Intl by plane?

    A flight from Panama City NW Florida Beaches to Louisville Intl will travel around 558.6 mi. In terms of flight time, this usually takes a little over 3h 30m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Louisville Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The necessary travel and health documents for your Louisville Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Louisville?

Best airlines flying from Panama City, Florida to Louisville

Compare and see reviews for airlines that fly from Panama City, Florida to Louisville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,242 reviews
Search Delta flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
New Albany
Shepherdsville
Corydon
Elizabeth
Brandenburg
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Louisville with flexible booking policies on momondo?

Yes. All flights to Louisville from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Louisville?

momondo helps you find the best flight between Panama City and Louisville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Louisville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Louisville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Louisville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 4/2
Thu 4/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States