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Cheap flights from Panama City, Florida to Buffalo from $132

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Buffalo departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:25 am - 4:46 pm
ECP
-
BUF
5h 21m
1 stop
United Airlines Logo
7:00 am - 1:21 pm
BUF
-
ECP
7h 21m
1 stop
$397United Airlines
Fri, May 29 - Tue, Jun 2
United Airlines Logo
10:25 am - 11:59 pm
ECP
-
BUF
12h 34m
2 stops
United Airlines Logo
7:00 am - 1:21 pm
BUF
-
ECP
7h 21m
1 stop
$402United Airlines
Fri, May 29 - Tue, Jun 2
United Airlines Logo
10:25 am - 4:46 pm
ECP
-
BUF
5h 21m
1 stop
United Airlines Logo
7:00 am - 1:21 pm
BUF
-
ECP
7h 21m
1 stop
$407United Airlines
Thu, Jul 2 - Mon, Jul 6
Southwest Logo
7:40 am - 2:20 pm
ECP
-
BUF
5h 40m
1 stop
Southwest Logo
6:00 am - 1:05 pm
BUF
-
ECP
8h 05m
2 stops
$412Southwest
Wed, Jul 15 - Fri, Aug 21
Southwest Logo
1:25 pm - 12:10 am
ECP
-
BUF
9h 45m
2 stops
Southwest Logo
6:20 am - 2:35 pm
BUF
-
ECP
9h 15m
2 stops
$417Southwest
Fri, Jul 10 - Sun, Aug 9
Delta Logo
5:49 am - 11:01 am
ECP
-
BUF
4h 12m
1 stop
Delta Logo
6:00 am - 12:19 pm
BUF
-
ECP
7h 19m
1 stop
$419Delta
Wed, Apr 15 - Wed, Apr 22
Southwest Logo
6:10 am - 3:30 pm
ECP
-
BUF
8h 20m
1 stop
Southwest Logo
6:20 am - 10:55 am
BUF
-
ECP
5h 35m
1 stop
$422Southwest
Fri, Jul 10 - Sun, Aug 9
United Airlines Logo
10:25 am - 11:59 pm
ECP
-
BUF
12h 34m
2 stops
United Airlines Logo
10:34 am - 8:01 pm
BUF
-
ECP
10h 27m
2 stops
$434United Airlines
Fri, May 29 - Tue, Jun 2
United Airlines Logo
10:10 am - 11:33 pm
ECP
-
BUF
12h 23m
2 stops
United Airlines Logo
7:00 am - 1:23 pm
BUF
-
ECP
7h 23m
1 stop
$437United Airlines
Thu, Apr 9 - Mon, Apr 13
Delta Logo
5:07 pm - 11:59 pm
ECP
-
BUF
5h 52m
1 stop
Delta Logo
6:05 am - 12:23 pm
BUF
-
ECP
7h 18m
1 stop
$443Delta
Thu, Jul 23 - Sun, Jul 26

Delta flights from Panama City, Florida to Buffalo

Our best Delta deals on Panama City, Florida to Buffalo flight tickets
Delta
Apr 15
ECP5:49 amPanama City NW Florida Beaches
4h 12m
1 stop
BUF11:01 amBuffalo
Apr 22
BUF6:00 amBuffalo
7h 19m
1 stop
ECP12:19 pmPanama City NW Florida Beaches
$419
Delta
Jul 23
ECP5:07 pmPanama City NW Florida Beaches
5h 52m
1 stop
BUF11:59 pmBuffalo
Jul 26
BUF6:05 amBuffalo
7h 18m
1 stop
ECP12:23 pmPanama City NW Florida Beaches
$443
Delta
Apr 15
ECP9:21 amPanama City NW Florida Beaches
5h 32m
1 stop
BUF3:53 pmBuffalo
Apr 22
BUF4:59 pmBuffalo
7h 13m
1 stop
ECP11:12 pmPanama City NW Florida Beaches
$498

United Airlines flights from Panama City, Florida to Buffalo

Our best United Airlines deals on Panama City, Florida to Buffalo flight tickets
United Airlines
May 29
ECP10:25 amPanama City NW Florida Beaches
5h 21m
1 stop
BUF4:46 pmBuffalo
Jun 2
BUF7:00 amBuffalo
7h 21m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
$397
United Airlines
May 29
ECP10:25 amPanama City NW Florida Beaches
12h 34m
2 stops
BUF11:59 pmBuffalo
Jun 2
BUF7:00 amBuffalo
7h 21m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
$402
United Airlines
Jul 2
ECP10:25 amPanama City NW Florida Beaches
5h 21m
1 stop
BUF4:46 pmBuffalo
Jul 6
BUF7:00 amBuffalo
7h 21m
1 stop
ECP1:21 pmPanama City NW Florida Beaches
$407

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 5/29

10:25 am-4:46 pm

1 stop5h 21m

Buffalo

Tue 6/2

7:00 am-1:21 pm

1 stop7h 21m

$397

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 5/29

10:25 am-11:59 pm

2 stops12h 34m

Buffalo

Tue 6/2

7:00 am-1:21 pm

1 stop7h 21m

$402

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Thu 7/2

10:25 am-4:46 pm

1 stop5h 21m

Buffalo

Mon 7/6

7:00 am-1:21 pm

1 stop7h 21m

$407

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 7/15

7:40 am-2:20 pm

1 stop5h 40m

Buffalo

Fri 8/21

6:00 am-1:05 pm

2 stops8h 05m

$412

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 7/10

1:25 pm-12:10 am

2 stops9h 45m

Buffalo

Sun 8/9

6:20 am-2:35 pm

2 stops9h 15m

$417
Quickest round-trip

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 4/15

5:49 am-11:01 am

1 stop4h 12m

Buffalo

Wed 4/22

6:00 am-12:19 pm

1 stop7h 19m

$419

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 7/10

6:10 am-3:30 pm

1 stop8h 20m

Buffalo

Sun 8/9

6:20 am-10:55 am

1 stop5h 35m

$422

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 5/29

10:25 am-11:59 pm

2 stops12h 34m

Buffalo

Tue 6/2

10:34 am-8:01 pm

2 stops10h 27m

$434

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Thu 4/9

10:10 am-11:33 pm

2 stops12h 23m

Buffalo

Mon 4/13

7:00 am-1:23 pm

1 stop7h 23m

$437

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Thu 7/23

5:07 pm-11:59 pm

1 stop5h 52m

Buffalo

Sun 7/26

6:05 am-12:23 pm

1 stop7h 18m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Panama City, Florida to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and Buffalo?

When to book flights from Panama City, Florida to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Buffalo (ECP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Buffalo

Fastest flight time

4h 13m

Direct flights

None
The fastest flight from Panama City, Florida to Buffalo takes 4h 13m
There are no direct flights from Panama City, Florida to Buffalo. There are no popular flight routes from Panama City, Florida to Buffalo.
Search flight deals

  • How far is Panama City NW Florida Beaches to Buffalo by plane?

    Buffalo is 955.1 mi away from Panama City NW Florida Beaches. In terms of flight time, this usually takes a little over 4h 13m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Buffalo Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Buffalo Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Buffalo Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Buffalo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Panama City, Florida to Buffalo?

Best airlines flying from Panama City, Florida to Buffalo

Compare and see reviews for airlines that fly from Panama City, Florida to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $236Free CancellationRating
7.1
11,506 reviews
Search American Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,341 reviews
Search Delta flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Orchard Park
Williamsville
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Panama City.

Can I find flights from Panama City to Buffalo with flexible booking policies on momondo?

All flight searches from Panama City to Buffalo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Buffalo?

Once you have performed a search for Panama City to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Buffalo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Buffalo from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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