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Cheap flights from Ohio to Knoxville from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Knoxville departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Ohio to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
4:36 pm - 10:00 pm
CAK
-
TYS
5h 24m
1 stop
Allegiant Air Logo
12:40 pm - 9:31 pm
TYS
-
CAK
8h 51m
1 stop
$177Allegiant Air
Fri, Jul 10 - Mon, Jul 13
Allegiant Air Logo
6:00 am - 10:01 pm
PIT
-
TYS
16h 01m
1 stop
Allegiant Air Logo
8:45 am - 10:32 pm
TYS
-
PIT
13h 47m
1 stop
$191Allegiant Air
Mon, Jun 1 - Sat, Jun 6
Multiple Airlines Logo
6:00 am - 10:01 pm
PIT
-
TYS
16h 01m
1 stop
Multiple Airlines Logo
12:49 pm - 2:22 pm
TYS
-
PIT
25h 33m
2 stops
$200Multiple Airlines
Mon, Jun 1 - Fri, Jun 5
Multiple Airlines Logo
5:30 am - 9:48 pm
CLE
-
TYS
16h 18m
1 stop
Multiple Airlines Logo
12:49 pm - 11:52 am
TYS
-
CLE
23h 03m
2 stops
$203Multiple Airlines
Mon, May 18 - Fri, Jun 12
Frontier Logo
12:08 pm - 7:33 pm
CLE
-
TYS
7h 25m
1 stop
Frontier Logo
8:32 pm - 11:03 am
TYS
-
CLE
14h 31m
1 stop
$210Frontier
Mon, Jun 8 - Wed, Jun 10
Frontier Logo
8:00 am - 7:36 pm
DTW
-
TYS
11h 36m
1 stop
Frontier Logo
8:32 pm - 12:34 pm
TYS
-
DTW
16h 02m
1 stop
$239Frontier
Fri, Jul 31 - Mon, Aug 3
Southwest Logo
3:50 pm - 9:15 pm
DTW
-
TYS
5h 25m
1 stop
Southwest Logo
7:10 am - 12:45 pm
TYS
-
DTW
5h 35m
1 stop
$299Southwest
Tue, Jun 9 - Tue, Jun 16
Southwest Logo
6:40 am - 5:00 pm
DTW
-
TYS
10h 20m
2 stops
Southwest Logo
7:10 am - 12:45 pm
TYS
-
DTW
5h 35m
1 stop
$304Southwest
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
1:01 pm - 8:10 pm
CMH
-
TYS
7h 09m
1 stop
American Airlines Logo
7:59 pm - 11:52 pm
TYS
-
CMH
3h 53m
1 stop
$324American Airlines
Sat, Jun 6 - Sat, Jun 13
American Airlines Logo
5:20 pm - 11:51 pm
ERI
-
TYS
6h 31m
1 stop
American Airlines Logo
7:00 am - 11:24 am
TYS
-
ERI
4h 24m
1 stop
$432American Airlines
Sat, Aug 1 - Sat, Aug 8

Frontier flights from Ohio to Knoxville

Our best Frontier deals on Ohio to Knoxville flight tickets
Frontier
Jun 8
CLE12:08 pmCleveland Hopkins Intl
7h 25m
1 stop
TYS7:33 pmKnoxville McGhee Tyson
Jun 10
TYS8:32 pmKnoxville McGhee Tyson
14h 31m
1 stop
CLE11:03 amCleveland Hopkins Intl
$210
Frontier
Jul 31
DTW8:00 amDetroit Metropolitan Wayne County
11h 36m
1 stop
TYS7:36 pmKnoxville McGhee Tyson
Aug 3
TYS8:32 pmKnoxville McGhee Tyson
16h 02m
1 stop
DTW12:34 pmDetroit Metropolitan Wayne County
$239
Frontier
Aug 3
DTW8:00 amDetroit Metropolitan Wayne County
11h 36m
1 stop
TYS7:36 pmKnoxville McGhee Tyson
Aug 7
TYS8:32 pmKnoxville McGhee Tyson
27h 27m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$242

United Airlines flights from Ohio to Knoxville

Our best United Airlines deals on Ohio to Knoxville flight tickets
United Airlines
Jun 9
PIT4:10 pmPittsburgh
4h 46m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
Jun 16
TYS6:00 amKnoxville McGhee Tyson
7h 07m
1 stop
PIT1:07 pmPittsburgh
$281
United Airlines
Jul 13
PIT6:16 pmPittsburgh
4h 18m
1 stop
TYS10:34 pmKnoxville McGhee Tyson
Jul 14
TYS6:00 amKnoxville McGhee Tyson
8h 03m
2 stops
PIT2:03 pmPittsburgh
$310
United Airlines
Jul 22
CVG10:18 amCincinnati Cinci./N. Kentucky
4h 09m
1 stop
TYS2:27 pmKnoxville McGhee Tyson
Jul 27
TYS7:19 pmKnoxville McGhee Tyson
4h 40m
1 stop
CVG11:59 pmCincinnati Cinci./N. Kentucky
$318

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Fri 7/10

4:36 pm-10:00 pm

1 stop5h 24m

Knoxville McGhee Tyson

Mon 7/13

12:40 pm-9:31 pm

1 stop8h 51m

$177

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Mon 6/1

6:00 am-10:01 pm

1 stop16h 01m

Knoxville McGhee Tyson

Sat 6/6

8:45 am-10:32 pm

1 stop13h 47m

$191

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Mon 6/1

6:00 am-10:01 pm

1 stop16h 01m

Knoxville McGhee Tyson

Fri 6/5

12:49 pm-2:22 pm

2 stops25h 33m

$200

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Mon 5/18

5:30 am-9:48 pm

1 stop16h 18m

Knoxville McGhee Tyson

Fri 6/12

12:49 pm-11:52 am

2 stops23h 03m

$203

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Mon 6/8

12:08 pm-7:33 pm

1 stop7h 25m

Knoxville McGhee Tyson

Wed 6/10

8:32 pm-11:03 am

1 stop14h 31m

$210

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 7/31

8:00 am-7:36 pm

1 stop11h 36m

Knoxville McGhee Tyson

Mon 8/3

8:32 pm-12:34 pm

1 stop16h 02m

$239

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 6/9

3:50 pm-9:15 pm

1 stop5h 25m

Knoxville McGhee Tyson

Tue 6/16

7:10 am-12:45 pm

1 stop5h 35m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 6/9

6:40 am-5:00 pm

2 stops10h 20m

Knoxville McGhee Tyson

Tue 6/16

7:10 am-12:45 pm

1 stop5h 35m

$304

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 6/6

1:01 pm-8:10 pm

1 stop7h 09m

Knoxville McGhee Tyson

Sat 6/13

7:59 pm-11:52 pm

1 stop3h 53m

$324
Quickest round-trip

ErieKnoxville

ERI - TYS

ERITYS

Erie

Sat 8/1

5:20 pm-11:51 pm

1 stop6h 31m

Knoxville McGhee Tyson

Sat 8/8

7:00 am-11:24 am

1 stop4h 24m

$432

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Ohio to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Ohio, with most prices found around $165. If you aren’t able to travel during the month of July, then book flights to Knoxville from Ohio during June instead. Flights to Knoxville in June, while not as cheap as those in July, still average around $184.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Fastest flight time

1h 33m

Direct flights

Every day

Airports in Knoxville

1 airport
The fastest flight from Ohio to Knoxville takes 1h 33m
Direct flights go from Ohio to Knoxville every day.
There is 1 airport in Knoxville. From Ohio there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Ohio to Knoxville

  • When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

    Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $213Free CancellationRating
7.9
8,446 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.1
11,661 reviews
Search American Airlines flights
United AirlinesPriceFrom $235Free CancellationRating
7.4
9,701 reviews
Search United Airlines flights
SouthwestPriceFrom $263Free CancellationRating
8.0
4,295 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Knoxville.

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Ohio and alert you when they change.

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