What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Ohio according to our data. American Airlines is the first choice among our users, with 73% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

Allegiant Air, Frontier, and American Airlines are the most popular carriers operating from Ohio to Knoxville McGhee Tyson

How many flights depart from Ohio to Knoxville on average per week?

As of July 2025, there are 72 flights per week flying from Ohio to Knoxville. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Ohio to Knoxville depends on which airport you fly into and out of. Flying from Cleveland to Knoxville is 3h 12m on average, while flying from Cincinnati to Knoxville is 3h 56m on average. Knoxville is the most popular airport in Knoxville.

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

As of July 2025, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$95 Cheap Flights from Ohio to Knoxville in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Ohio to Knoxville

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:00 am - 6:45 pmPIT-TYS

11h 45m1 stop

7:30 am - 11:22 pmTYS-PIT

15h 52m2 stops

$184

Find Deal

Thu, Sep 4 - Tue, Sep 9

6:00 am - 5:38 pmCMH-TYS

11h 38m1 stop

1:22 pm - 9:46 pmTYS-CMH

8h 24m1 stop

$187

Find Deal

Fri, Aug 22 - Mon, Aug 25

5:56 pm - 11:48 pmPIT-TYS

5h 52m1 stop

6:14 pm - 11:10 pmTYS-PIT

4h 56m1 stop

$214Delta

Find Deal

Sat, Aug 23 - Sat, Aug 30

6:00 am - 11:22 amCMH-TYS

5h 22m1 stop

4:53 pm - 9:25 pmTYS-CMH

4h 32m1 stop

$219American Airlines

Find Deal

Tue, Sep 2 - Sat, Sep 6

1:19 pm - 7:45 pmCVG-TYS

6h 26m1 stop

3:04 pm - 7:57 pmTYS-CVG

4h 53m1 stop

$219American Airlines

Find Deal

Sun, Aug 24 - Sun, Aug 31

7:45 pm - 11:48 pmCMH-TYS

4h 03m1 stop

7:50 am - 1:29 pmTYS-CMH

5h 39m1 stop

$224Delta

Find Deal

Mon, Aug 18 - Mon, Aug 25

8:10 pm - 11:59 pmPIT-TYS

3h 49m1 stop

5:45 am - 9:28 amTYS-PIT

3h 43m1 stop

$232United Airlines

Find Deal

Thu, Nov 20 - Fri, Nov 28

11:54 am - 7:50 pmDTW-TYS

7h 56m1 stop

5:08 pm - 12:46 amTYS-DTW

7h 38m1 stop

$239Frontier

Find Deal

Thu, Oct 2 - Sun, Oct 5

6:00 am - 10:17 amCVG-TYS

4h 17m1 stop

5:45 am - 10:30 amTYS-CVG

4h 45m1 stop

$244United Airlines

Find Deal

Wed, Aug 13 - Sun, Aug 17

8:11 pm - 6:25 pmCLE-TYS

22h 14m1 stop

8:40 pm - 7:06 pmTYS-CLE

22h 26m1 stop

$245Frontier

Find Deal

Sun, Aug 31 - Thu, Sep 4

American Airlines flights from Ohio to Knoxville

Our best American Airlines deals on Ohio to Knoxville flight tickets

American Airlines

Sep 2

CMH6:00 amColumbus

5h 22m

1 stop

TYS11:22 amKnoxville McGhee Tyson

Sep 6

TYS4:53 pmKnoxville McGhee Tyson

4h 32m

1 stop

CMH9:25 pmColumbus

$219

Find similar

American Airlines

Aug 14

CMH6:14 amColumbus

4h 16m

1 stop

TYS10:30 amKnoxville McGhee Tyson

Aug 16

TYS7:55 amKnoxville McGhee Tyson

5h 58m

1 stop

CMH1:53 pmColumbus

$229

Find similar

American Airlines

Sep 20

CLE4:19 pmCleveland Hopkins Intl

6h 44m

2 stops

TYS11:03 pmKnoxville McGhee Tyson

Sep 24

TYS8:23 amKnoxville McGhee Tyson

4h 08m

1 stop

CLE12:31 pmCleveland Hopkins Intl

$234

Find similar

Frontier flights from Ohio to Knoxville

Our best Frontier deals on Ohio to Knoxville flight tickets

Frontier

Oct 2

DTW11:54 amDetroit Metropolitan Wayne County

7h 56m

1 stop

TYS7:50 pmKnoxville McGhee Tyson

Oct 5

TYS5:08 pmKnoxville McGhee Tyson

7h 38m

1 stop

DTW12:46 amDetroit Metropolitan Wayne County

$239

Find similar

Frontier

Aug 21

DTW11:54 amDetroit Metropolitan Wayne County

7h 47m

1 stop

TYS7:41 pmKnoxville McGhee Tyson

Aug 25

TYS7:10 pmKnoxville McGhee Tyson

26h 33m

1 stop

DTW9:43 pmDetroit Metropolitan Wayne County

$245

Find similar

Frontier

Aug 7

DTW6:00 amDetroit Metropolitan Wayne County

10h 29m

1 stop

TYS4:29 pmKnoxville McGhee Tyson

Aug 10

TYS5:25 pmKnoxville McGhee Tyson

7h 17m

1 stop

DTW12:42 amDetroit Metropolitan Wayne County

$268

Find similar

Fly from

Fly to

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Thu 9/4

7:00 am-6:45 pm

1 stop11h 45m

Knoxville McGhee Tyson

Tue 9/9

7:30 am-11:22 pm

2 stops15h 52m

$184

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 8/22

6:00 am-5:38 pm

1 stop11h 38m

Knoxville McGhee Tyson

Mon 8/25

1:22 pm-9:46 pm

1 stop8h 24m

$187

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 8/23

5:56 pm-11:48 pm

1 stop5h 52m

Knoxville McGhee Tyson

Sat 8/30

6:14 pm-11:10 pm

1 stop4h 56m

$214

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 9/2

6:00 am-11:22 am

1 stop5h 22m

Knoxville McGhee Tyson

Sat 9/6

4:53 pm-9:25 pm

1 stop4h 32m

$219

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Sun 8/24

1:19 pm-7:45 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sun 8/31

3:04 pm-7:57 pm

1 stop4h 53m

$219

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 8/18

7:45 pm-11:48 pm

1 stop4h 03m

Knoxville McGhee Tyson

Mon 8/25

7:50 am-1:29 pm

1 stop5h 39m

$224

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Thu 11/20

8:10 pm-11:59 pm

1 stop3h 49m

Knoxville McGhee Tyson

Fri 11/28

5:45 am-9:28 am

1 stop3h 43m

$232

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 10/2

11:54 am-7:50 pm

1 stop7h 56m

Knoxville McGhee Tyson

Sun 10/5

5:08 pm-12:46 am

1 stop7h 38m

$239

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Wed 8/13

6:00 am-10:17 am

1 stop4h 17m

Knoxville McGhee Tyson

Sun 8/17

5:45 am-10:30 am

1 stop4h 45m

$244

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sun 8/31

8:11 pm-6:25 pm

1 stop22h 14m

Knoxville McGhee Tyson

Thu 9/4

8:40 pm-7:06 pm

1 stop22h 26m

$245

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Ohio to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Ohio, with most prices found around $233. If you aren’t able to travel during the month of February, then book flights to Knoxville from Ohio during November instead. Flights to Knoxville in November, while not as cheap as those in February, still average around $258.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Ohio to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $258. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Ohio to Knoxville for around $418.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Ohio to Knoxville when you can find flight prices for as low as $264. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $392.

What is the cheapest Ohio to Knoxville McGhee Tyson flight route?

Fly from Columbus to Knoxville McGhee Tyson for the best Ohio - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $293 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Ohio for as low as $228 on momondo.

What cabin class options are available on Ohio to Knoxville McGhee Tyson flights?

There are 1 cabin classes available to choose from on Ohio to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Best Price Found	$95
Fastest flight time	3h 04m
Direct flights	Every day
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Ohio in the past 72 hours is $95. The best round-trip flight deal from Ohio to Knoxville found on momondo in the last 72 hours is $184.

The fastest flight from Ohio to Knoxville takes 3h 04m

Direct flights go from Ohio to Knoxville every day.

There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

Search flight deals

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?
Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?
As of July 2025, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $198	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.4 8,900 reviews	Search United Airlines flights
American Airlines	PriceFrom $213	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Newport

Alcoa

Lenoir City

Oak Ridge

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Knoxville.

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Ohio and alert you when they change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Tue 8/5

Tue 8/12

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Cheap flights from Ohio to Knoxville from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Knoxville departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Ohio to Knoxville

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from Ohio to Knoxville

Our best American Airlines deals on Ohio to Knoxville flight tickets

Frontier flights from Ohio to Knoxville

Our best Frontier deals on Ohio to Knoxville flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

See travel insights to Knoxville from

How to get the cheapest flight ticket from Ohio to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

What is the cheapest Ohio to Knoxville McGhee Tyson flight route?

Fly from Columbus to Knoxville McGhee Tyson for the best Ohio - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

What cabin class options are available on Ohio to Knoxville McGhee Tyson flights?

There are 1 cabin classes available to choose from on Ohio to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

Allegiant Air, Frontier, and American Airlines are the most popular carriers operating from Ohio to Knoxville McGhee Tyson

What airlines fly to Knoxville?

How many flights depart from Ohio to Knoxville on average per week?

As of July 2025, there are 72 flights per week flying from Ohio to Knoxville. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Ohio to Knoxville depends on which airport you fly into and out of. Flying from Cleveland to Knoxville is 3h 12m on average, while flying from Cincinnati to Knoxville is 3h 56m on average. Knoxville is the most popular airport in Knoxville.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Best Price Found

Fastest flight time

Direct flights

Airports in Knoxville

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Knoxville?

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Ohio to Knoxville?

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee