What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Ohio according to our data. American Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

Frontier, American Airlines, and United Airlines are the most popular carriers operating from Ohio to Knoxville McGhee Tyson

How many flights depart from Ohio to Knoxville on average per week?

As of December 2025, there are 22 flights per week flying from Ohio to Knoxville. The most common day of the week flights depart is Tue, with 23% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Ohio to Knoxville depends on which airport you fly into and out of. Flying from Cincinnati to Knoxville is 3h 17m on average, while flying from Cleveland to Knoxville is 3h 32m on average. Knoxville is the most popular airport in Knoxville.

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

As of December 2025, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$81 Cheap Flights from Ohio to Knoxville in 2025/26

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:50 pm - 8:39 am

PIT

TYS

14h 49m1 stop

4:47 pm - 11:44 pm

TYS

PIT

6h 57m1 stop

$170Multiple Airlines

Wed, Jan 21 - Wed, Jan 28

2:53 pm - 9:21 pm

CAK

TYS

6h 28m1 stop

11:50 am - 5:35 pm

TYS

CAK

5h 45m1 stop

$173Multiple Airlines

Thu, Feb 19 - Thu, Feb 26

4:24 pm - 4:47 pm

CVG

TYS

24h 23m1 stop

6:00 am - 2:15 pm

TYS

CVG

8h 15m1 stop

$225Allegiant Air

Mon, Jan 5 - Fri, Jan 9

10:53 am - 4:17 pm

CLE

TYS

5h 24m1 stop

5:02 pm - 10:27 pm

TYS

CLE

5h 25m1 stop

$235Delta

Thu, Feb 26 - Mon, Mar 2

10:00 am - 6:41 pm

CVG

TYS

8h 41m1 stop

7:26 pm - 7:45 pm

TYS

CVG

24h 19m1 stop

$253Allegiant Air

Sun, Jan 18 - Sun, Jan 25

7:00 am - 1:24 pm

CVG

TYS

6h 24m1 stop

11:10 am - 4:43 pm

TYS

CVG

5h 33m1 stop

$255United Airlines

Tue, Jan 20 - Tue, Jan 27

7:04 am - 1:54 pm

CVG

TYS

6h 50m2 stops

5:15 pm - 10:00 pm

TYS

CVG

4h 45m1 stop

$260American Airlines

Tue, Jan 20 - Tue, Jan 27

6:10 am - 1:24 pm

PIT

TYS

7h 14m2 stops

2:25 pm - 11:38 pm

TYS

PIT

9h 13m2 stops

$261United Airlines

Wed, Jan 21 - Wed, Jan 28

6:00 am - 9:52 am

CLE

TYS

3h 52m1 stop

6:40 am - 12:24 pm

TYS

CLE

5h 44m1 stop

$270American Airlines

Wed, Mar 4 - Fri, Mar 6

3:52 pm - 7:24 pm

CLE

TYS

3h 32m1 stop

5:26 pm - 10:27 pm

TYS

CLE

5h 01m1 stop

$283Delta

Sat, Jan 17 - Sun, Jan 18

Delta flights from Ohio to Knoxville

Our best Delta deals on Ohio to Knoxville flight tickets

Delta

Feb 26

CLE10:53 amCleveland Hopkins Intl

5h 24m

1 stop

TYS4:17 pmKnoxville McGhee Tyson

Mar 2

TYS5:02 pmKnoxville McGhee Tyson

5h 25m

1 stop

CLE10:27 pmCleveland Hopkins Intl

$235

Find similar

Delta

Jan 17

CLE3:52 pmCleveland Hopkins Intl

3h 32m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

Jan 18

TYS5:26 pmKnoxville McGhee Tyson

5h 01m

1 stop

CLE10:27 pmCleveland Hopkins Intl

$283

Find similar

Delta

Feb 2

PIT2:07 pmPittsburgh

6h 40m

1 stop

TYS8:47 pmKnoxville McGhee Tyson

Feb 6

TYS11:58 amKnoxville McGhee Tyson

6h 35m

1 stop

PIT6:33 pmPittsburgh

$295

Find similar

American Airlines flights from Ohio to Knoxville

Our best American Airlines deals on Ohio to Knoxville flight tickets

American Airlines

Feb 20

CAK5:03 pmAkron/Canton

4h 20m

1 stop

TYS9:23 pmKnoxville McGhee Tyson

Feb 25

TYS8:50 amKnoxville McGhee Tyson

7h 43m

2 stops

CAK4:33 pmAkron/Canton

$254

Find similar

American Airlines

Jan 6

CAK6:28 amAkron/Canton

6h 18m

1 stop

TYS12:46 pmKnoxville McGhee Tyson

Jan 10

TYS3:00 pmKnoxville McGhee Tyson

4h 13m

1 stop

CAK7:13 pmAkron/Canton

$259

Find similar

American Airlines

Jan 20

CVG7:04 amCincinnati Cinci./N. Kentucky

6h 50m

2 stops

TYS1:54 pmKnoxville McGhee Tyson

Jan 27

TYS5:15 pmKnoxville McGhee Tyson

4h 45m

1 stop

CVG10:00 pmCincinnati Cinci./N. Kentucky

$260

Find similar

Fly from

Fly to

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 1/21

5:50 pm-8:39 am

1 stop14h 49m

Knoxville McGhee Tyson

Wed 1/28

4:47 pm-11:44 pm

1 stop6h 57m

$170

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Thu 2/19

2:53 pm-9:21 pm

1 stop6h 28m

Knoxville McGhee Tyson

Thu 2/26

11:50 am-5:35 pm

1 stop5h 45m

$173

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Mon 1/5

4:24 pm-4:47 pm

1 stop24h 23m

Knoxville McGhee Tyson

Fri 1/9

6:00 am-2:15 pm

1 stop8h 15m

$225

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Thu 2/26

10:53 am-4:17 pm

1 stop5h 24m

Knoxville McGhee Tyson

Mon 3/2

5:02 pm-10:27 pm

1 stop5h 25m

$235

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Sun 1/18

10:00 am-6:41 pm

1 stop8h 41m

Knoxville McGhee Tyson

Sun 1/25

7:26 pm-7:45 pm

1 stop24h 19m

$253

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Tue 1/20

7:00 am-1:24 pm

1 stop6h 24m

Knoxville McGhee Tyson

Tue 1/27

11:10 am-4:43 pm

1 stop5h 33m

$255

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Tue 1/20

7:04 am-1:54 pm

2 stops6h 50m

Knoxville McGhee Tyson

Tue 1/27

5:15 pm-10:00 pm

1 stop4h 45m

$260

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 1/21

6:10 am-1:24 pm

2 stops7h 14m

Knoxville McGhee Tyson

Wed 1/28

2:25 pm-11:38 pm

2 stops9h 13m

$261

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Wed 3/4

6:00 am-9:52 am

1 stop3h 52m

Knoxville McGhee Tyson

Fri 3/6

6:40 am-12:24 pm

1 stop5h 44m

$270

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 1/17

3:52 pm-7:24 pm

1 stop3h 32m

Knoxville McGhee Tyson

Sun 1/18

5:26 pm-10:27 pm

1 stop5h 01m

$283

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How to get the cheapest flight ticket from Ohio to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Ohio, with most prices found around $238. If you aren’t able to travel during the month of February, then book flights to Knoxville from Ohio during September instead. Flights to Knoxville in September, while not as cheap as those in February, still average around $268.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Ohio to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $258. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Ohio to Knoxville for around $418.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Ohio to Knoxville when you can find flight prices for as low as $264. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $392.

What is the cheapest Ohio to Knoxville McGhee Tyson flight route?

Fly from Columbus to Knoxville McGhee Tyson for the best Ohio - Knoxville McGhee Tyson flight prices

What cabin class options are available on Ohio to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Ohio to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Fastest flight time	1h 33m
Direct flights	Every day
Airports in Knoxville	1 airport

The fastest flight from Ohio to Knoxville takes 1h 33m

Direct flights go from Ohio to Knoxville every day.

There is 1 airport in Knoxville. From Ohio there are direct flights to Knoxville McGhee Tyson (TYS).

Search flight deals

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?
Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?
As of December 2025, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.4 9,105 reviews	Search United Airlines flights
Delta	PriceFrom $213	Free Cancellation	Rating 7.9 8,014 reviews	Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,054 reviews	Search American Airlines flights

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Rockford

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Why should I use momondo to find a flight deal from Ohio to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Knoxville.

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Ohio and alert you when they change.

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Cheap flights from Ohio to Knoxville from $81

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Knoxville departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Ohio to Knoxville

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

What is the cheapest Ohio to Knoxville McGhee Tyson flight route?

Fly from Columbus to Knoxville McGhee Tyson for the best Ohio - Knoxville McGhee Tyson flight prices

What cabin class options are available on Ohio to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Ohio to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

Frontier, American Airlines, and United Airlines are the most popular carriers operating from Ohio to Knoxville McGhee Tyson

What airlines fly to Knoxville?

How many flights depart from Ohio to Knoxville on average per week?

As of December 2025, there are 22 flights per week flying from Ohio to Knoxville. The most common day of the week flights depart is Tue, with 23% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Ohio to Knoxville depends on which airport you fly into and out of. Flying from Cincinnati to Knoxville is 3h 17m on average, while flying from Cleveland to Knoxville is 3h 32m on average. Knoxville is the most popular airport in Knoxville.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Fastest flight time

Direct flights

Airports in Knoxville

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Knoxville?

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Ohio to Knoxville?

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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Airports servicing Tennessee