What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Ohio according to our data. American Airlines is the first choice among our users, with 72% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

How many flights depart from Ohio to Knoxville on average per week?

As of February 2026, there are 42 flights per week flying from Ohio to Knoxville. The most common day of the week flights depart is Tue, with 19% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Ohio to Knoxville depends on which airport you fly into and out of. Flying from Cleveland to Knoxville is 4h on average, while flying from Columbus to Knoxville is 4h 15m on average. Knoxville is the most popular airport in Knoxville.

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

Allegiant Air, Delta, and Southwest are the most popular carriers operating from Ohio to Knoxville McGhee Tyson

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?

Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?

As of February 2026, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$93 Cheap Flights from Ohio to Knoxville in 2026

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Find the cheapest flights from Ohio to Knoxville

Round-trip

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Cheap round-trip flights

Enter your travel dates to find the best prices.

4:47 pm - 6:26 pm

CLE

TYS

25h 39m

1 stop

6:24 pm - 7:42 am

TYS

CLE

13h 18m

1 stop

$173Multiple Airlines

Tue, Mar 3 - Tue, Mar 10

4:47 pm - 6:26 pm

CLE

TYS

25h 39m

1 stop

6:24 pm - 7:42 am

TYS

CLE

13h 18m

1 stop

$174Multiple Airlines

Tue, Mar 3 - Tue, Mar 10

2:41 pm - 8:40 pm

CMH

TYS

5h 59m

1 stop

4:02 pm - 11:28 pm

TYS

CMH

7h 26m

1 stop

$251American Airlines

Wed, Mar 4 - Wed, Mar 11

6:10 am - 10:50 am

PIT

TYS

4h 40m

1 stop

7:00 am - 1:05 pm

TYS

PIT

6h 05m

1 stop

$251United Airlines

Sat, Apr 18 - Sat, Apr 25

6:10 am - 1:17 pm

PIT

TYS

7h 07m

2 stops

7:00 am - 1:05 pm

TYS

PIT

6h 05m

1 stop

$256United Airlines

Sat, Apr 18 - Sat, Apr 25

4:15 pm - 8:05 pm

DTW

TYS

3h 50m

1 stop

6:35 am - 12:15 pm

TYS

DTW

5h 40m

1 stop

$257Southwest

Wed, Mar 11 - Wed, Mar 18

8:20 pm - 10:43 pm

CAK

TYS

26h 23m

1 stop

11:05 am - 4:44 pm

TYS

CAK

5h 39m

1 stop

$269Allegiant Air

Sun, Mar 22 - Thu, Mar 26

5:58 pm - 10:24 pm

PIT

TYS

4h 26m

1 stop

6:00 am - 1:00 pm

TYS

PIT

7h 00m

1 stop

$288American Airlines

Fri, Apr 24 - Tue, Apr 28

5:55 pm - 10:10 pm

CMH

TYS

4h 15m

1 stop

6:30 am - 6:05 pm

TYS

CMH

11h 35m

2 stops

$306Southwest

Mon, Mar 16 - Thu, Mar 19

3:30 pm - 10:24 pm

CVG

TYS

6h 54m

1 stop

8:40 am - 6:11 pm

TYS

CVG

9h 31m

1 stop

$306Allegiant Air

Fri, Mar 6 - Fri, Mar 13

Allegiant Air flights from Ohio to Knoxville

Our best Allegiant Air deals on Ohio to Knoxville flight tickets

Allegiant Air

Mar 22

CAK8:20 pmAkron/Canton

26h 23m

1 stop

TYS10:43 pmKnoxville McGhee Tyson

Mar 26

TYS11:05 amKnoxville McGhee Tyson

5h 39m

1 stop

CAK4:44 pmAkron/Canton

$269

Allegiant Air

Mar 22

PIT1:09 pmPittsburgh

7h 33m

1 stop

TYS8:42 pmKnoxville McGhee Tyson

Mar 26

TYS11:05 amKnoxville McGhee Tyson

12h 24m

1 stop

PIT11:29 pmPittsburgh

$302

Allegiant Air

Mar 6

CVG3:30 pmCincinnati Cinci./N. Kentucky

6h 54m

1 stop

TYS10:24 pmKnoxville McGhee Tyson

Mar 13

TYS8:40 amKnoxville McGhee Tyson

9h 31m

1 stop

CVG6:11 pmCincinnati Cinci./N. Kentucky

$306

American Airlines flights from Ohio to Knoxville

Our best American Airlines deals on Ohio to Knoxville flight tickets

American Airlines

Apr 24

PIT5:58 pmPittsburgh

4h 26m

1 stop

TYS10:24 pmKnoxville McGhee Tyson

Apr 28

TYS6:00 amKnoxville McGhee Tyson

7h 00m

1 stop

PIT1:00 pmPittsburgh

$288

American Airlines

Feb 24

CAK6:30 amAkron/Canton

4h 18m

1 stop

TYS10:48 amKnoxville McGhee Tyson

Feb 28

TYS7:02 amKnoxville McGhee Tyson

4h 13m

1 stop

CAK11:15 amAkron/Canton

$289

American Airlines

Mar 9

PIT5:10 pmPittsburgh

4h 44m

1 stop

TYS9:54 pmKnoxville McGhee Tyson

Mar 15

TYS5:00 amKnoxville McGhee Tyson

4h 11m

1 stop

PIT9:11 amPittsburgh

$295

Fly from

Fly to

Route

Depart

Return

Price

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Tue 3/3

4:47 pm-6:26 pm

1 stop25h 39m

Knoxville McGhee Tyson

Tue 3/10

6:24 pm-7:42 am

1 stop13h 18m

$173

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Tue 3/3

4:47 pm-6:26 pm

1 stop25h 39m

Knoxville McGhee Tyson

Tue 3/10

6:24 pm-7:42 am

1 stop13h 18m

$174

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Wed 3/4

2:41 pm-8:40 pm

1 stop5h 59m

Knoxville McGhee Tyson

Wed 3/11

4:02 pm-11:28 pm

1 stop7h 26m

$251

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 4/18

6:10 am-10:50 am

1 stop4h 40m

Knoxville McGhee Tyson

Sat 4/25

7:00 am-1:05 pm

1 stop6h 05m

$251

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 4/18

6:10 am-1:17 pm

2 stops7h 07m

Knoxville McGhee Tyson

Sat 4/25

7:00 am-1:05 pm

1 stop6h 05m

$256

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 3/11

4:15 pm-8:05 pm

1 stop3h 50m

Knoxville McGhee Tyson

Wed 3/18

6:35 am-12:15 pm

1 stop5h 40m

$257

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Sun 3/22

8:20 pm-10:43 pm

1 stop26h 23m

Knoxville McGhee Tyson

Thu 3/26

11:05 am-4:44 pm

1 stop5h 39m

$269

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Fri 4/24

5:58 pm-10:24 pm

1 stop4h 26m

Knoxville McGhee Tyson

Tue 4/28

6:00 am-1:00 pm

1 stop7h 00m

$288

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 3/16

5:55 pm-10:10 pm

1 stop4h 15m

Knoxville McGhee Tyson

Thu 3/19

6:30 am-6:05 pm

2 stops11h 35m

$306

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Fri 3/6

3:30 pm-10:24 pm

1 stop6h 54m

Knoxville McGhee Tyson

Fri 3/13

8:40 am-6:11 pm

1 stop9h 31m

$306

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How to get the cheapest flight ticket from Ohio to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

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Other information

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Ohio, with most prices found around $267. If you aren’t able to travel during the month of February, then book flights to Knoxville from Ohio during July instead. Flights to Knoxville in July, while not as cheap as those in February, still average around $274.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $345 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Ohio for as low as $283 on momondo.

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Fastest flight time	1h 32m
Direct flights	Every day
Airports in Knoxville	1 airport

The fastest flight from Ohio to Knoxville takes 1h 32m

Direct flights go from Ohio to Knoxville every day.

There is 1 airport in Knoxville. From Ohio there are direct flights to Knoxville McGhee Tyson (TYS).

Search flight deals

When did momondo last update prices for flights from Ohio to Knoxville McGhee Tyson Airport?
Prices for flights from Ohio to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Ohio to Knoxville McGhee Tyson Airport?
As of February 2026, there are 3 operators available to choose from for flights from Ohio to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Ohio to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $213	Free Cancellation	Rating 7.9 8,179 reviews	Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,267 reviews	Search American Airlines flights
United Airlines	PriceFrom $238	Free Cancellation	Rating 7.4 9,276 reviews	Search United Airlines flights

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Morristown

Corbin

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Murphy

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Rockford

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Why should I use momondo to find a flight deal from Ohio to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Knoxville.

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Ohio and alert you when they change.

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Cheap flights from Ohio to Knoxville from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Knoxville departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Ohio to Knoxville

What is the cheapest month to fly to Knoxville?

How far in advance should I book a flight to Knoxville?

What is the cheapest airline that flies from Ohio to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

How many flights depart from Ohio to Knoxville on average per week?

How long does it take to fly to Knoxville?

Cheap Ohio to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Knoxville

Fastest flight time

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Airports in Knoxville

Best airlines flying from Ohio to Knoxville

Compare and see reviews for airlines that fly from Ohio to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Knoxville?

Can I find flights from Ohio to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Ohio to Knoxville?

I’m not ready to book a flight from Ohio to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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Fly your favorite airline to Knoxville

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List of cabin classes available on flights landing in Knoxville. Availability may vary depending on flight origin and airline.

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