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Cheap flights from Chicago O'Hare Intl Airport to South Carolina from $58

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to South Carolina departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
4:03 pm - 7:03 pmORD-CLT
2h 00mnonstop
Spirit Airlines Logo
5:45 am - 1:26 pmCLT-ORD
8h 41m1 stop
$87Spirit Airlines
Find Deal
sáb., nov. 1 - jue., nov. 6
Frontier Logo
6:50 am - 9:57 amORD-CLT
2h 07mnonstop
Frontier Logo
10:52 am - 12:05 pmCLT-ORD
2h 13mnonstop
$88Frontier
Find Deal
mar., dic. 23 - mar., dic. 30
United Airlines Logo
2:15 pm - 5:20 pmORD-CLT
2h 05mnonstop
United Airlines Logo
5:28 pm - 6:54 pmCLT-ORD
2h 26mnonstop
$127United Airlines
Find Deal
jue., dic. 4 - sáb., dic. 6
Delta Logo
11:15 am - 6:01 pmORD-MYR
5h 46m1 stop
Delta Logo
11:09 am - 4:19 pmMYR-ORD
6h 10m1 stop
$187Delta
Find Deal
jue., dic. 18 - lun., dic. 22
American Airlines Logo
6:53 pm - 10:00 pmORD-GSP
2h 07mnonstop
American Airlines Logo
6:12 am - 7:30 amGSP-ORD
2h 18mnonstop
$219American Airlines
Find Deal
jue., nov. 13 - dom., nov. 16
Delta Logo
4:20 pm - 11:40 pmORD-GSP
6h 20m1 stop
Delta Logo
5:35 am - 8:42 amGSP-ORD
4h 07m1 stop
$222Delta
Find Deal
mié., dic. 10 - dom., dic. 14
American Airlines Logo
6:04 am - 11:50 amORD-MYR
4h 46m1 stop
American Airlines Logo
5:44 pm - 11:44 pmMYR-ORD
7h 00m1 stop
$228American Airlines
Find Deal
vie., ene. 16 - lun., ene. 19
United Airlines Logo
6:15 pm - 9:30 pmORD-CAE
2h 15mnonstop
United Airlines Logo
2:29 pm - 4:02 pmCAE-ORD
2h 33mnonstop
$241United Airlines
Find Deal
vie., nov. 21 - dom., nov. 23
Southwest Logo
2:15 pm - 11:30 pmORD-CHS
8h 15m2 stops
Southwest Logo
6:00 am - 12:15 pmCHS-ORD
7h 15m1 stop
$286Southwest
Find Deal
jue., dic. 18 - jue., ene. 1
Southwest Logo
6:05 am - 7:50 pmORD-CHS
12h 45m2 stops
Southwest Logo
10:35 am - 9:50 pmCHS-ORD
12h 15m2 stops
$290Southwest
Find Deal
sáb., dic. 6 - mié., dic. 10

Frontier flights from Chicago O'Hare Intl Airport to South Carolina

Our best Frontier deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
Frontier
Dec 23
ORD6:50 amChicago O'Hare Intl
2h 07m
CLT9:57 amCharlotte Douglas
Dec 30
CLT10:52 amCharlotte Douglas
2h 13m
ORD12:05 pmChicago O'Hare Intl
$88
Find similar
Frontier
Nov 8
ORD11:51 amChicago O'Hare Intl
2h 05m
CLT2:56 pmCharlotte Douglas
Nov 10
CLT3:53 pmCharlotte Douglas
2h 22m
ORD5:15 pmChicago O'Hare Intl
$91
Find similar
Frontier
Nov 13
ORD11:50 amChicago O'Hare Intl
2h 05m
CLT2:55 pmCharlotte Douglas
Nov 17
CLT3:53 pmCharlotte Douglas
2h 22m
ORD5:15 pmChicago O'Hare Intl
$92
Find similar

Spirit Airlines flights from Chicago O'Hare Intl Airport to South Carolina

Our best Spirit Airlines deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
Spirit Airlines
Nov 1
ORD4:03 pmChicago O'Hare Intl
2h 00m
CLT7:03 pmCharlotte Douglas
Nov 6
CLT5:45 amCharlotte Douglas
8h 41m
1 stop
ORD1:26 pmChicago O'Hare Intl
$87
Find similar
Spirit Airlines
Nov 1
ORD4:03 pmChicago O'Hare Intl
2h 00m
CLT7:03 pmCharlotte Douglas
Nov 5
CLT6:00 amCharlotte Douglas
9h 31m
1 stop
ORD2:31 pmChicago O'Hare Intl
$97
Find similar
Spirit Airlines
Nov 10
ORD2:31 pmChicago O'Hare Intl
7h 37m
1 stop
CLT11:08 pmCharlotte Douglas
Nov 12
CLT6:00 amCharlotte Douglas
9h 31m
1 stop
ORD2:31 pmChicago O'Hare Intl
$99
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 11/1

4:03 pm-7:03 pm

Nonstop2h 00m

Charlotte Douglas

jue. 11/6

5:45 am-1:26 pm

1 stop8h 41m

$87

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mar. 12/23

6:50 am-9:57 am

Nonstop2h 07m

Charlotte Douglas

mar. 12/30

10:52 am-12:05 pm

Nonstop2h 13m

$88

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 12/4

2:15 pm-5:20 pm

Nonstop2h 05m

Charlotte Douglas

sáb. 12/6

5:28 pm-6:54 pm

Nonstop2h 26m

$127

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

jue. 12/18

11:15 am-6:01 pm

1 stop5h 46m

Myrtle Beach Intl

lun. 12/22

11:09 am-4:19 pm

1 stop6h 10m

$187

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

jue. 11/13

6:53 pm-10:00 pm

Nonstop2h 07m

Greenville

dom. 11/16

6:12 am-7:30 am

Nonstop2h 18m

$219

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mié. 12/10

4:20 pm-11:40 pm

1 stop6h 20m

Greenville

dom. 12/14

5:35 am-8:42 am

1 stop4h 07m

$222

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

vie. 1/16

6:04 am-11:50 am

1 stop4h 46m

Myrtle Beach Intl

lun. 1/19

5:44 pm-11:44 pm

1 stop7h 00m

$228

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

vie. 11/21

6:15 pm-9:30 pm

Nonstop2h 15m

Columbia Metropolitan

dom. 11/23

2:29 pm-4:02 pm

Nonstop2h 33m

$241

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

jue. 12/18

2:15 pm-11:30 pm

2 stops8h 15m

Charleston

jue. 1/1

6:00 am-12:15 pm

1 stop7h 15m

$286

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

sáb. 12/6

6:05 am-7:50 pm

2 stops12h 45m

Charleston

mié. 12/10

10:35 am-9:50 pm

2 stops12h 15m

$290

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago O'Hare Intl Airport is in August. Flight prices, which tend to average around $326, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Chicago O'Hare Intl Airport during September instead. Flights to South Carolina in September, while not as cheap as those in August, still average around $327.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $365. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $413.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago O'Hare Intl Airport to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $362. Try not to purchase tickets in the afternoon because they tend to be around $396. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago O'Hare Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago O'Hare Intl Airport for as low as $320 on momondo.

What cabin class options are available on Chicago O'Hare Intl to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to South Carolina.

Cheap Chicago O'Hare Intl Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to South Carolina

Best Price Found

$146

Fastest flight time

1h 48m

Direct flights

Every day

Airports in South Carolina

2 airports
The best one-way flight to South Carolina from Chicago O'Hare Intl Airport in the past 72 hours is $146. The best round-trip flight deal from Chicago O'Hare Intl Airport to South Carolina found on momondo in the last 72 hours is $229.
The fastest flight from Chicago O'Hare Intl Airport to South Carolina takes 1h 48m
Direct flights go from Chicago O'Hare Intl Airport to South Carolina every day.
There are 2 airports near South Carolina: Greenville (GSP), Charlotte Douglas (CLT)
Search flight deals

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to South Carolina?

    Prices for flights from Chicago O'Hare Intl Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to South Carolina?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to South Carolina?

Best airlines flying from Chicago O'Hare Intl Airport to South Carolina

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $64Free CancellationRating
6.3
8,103 reviews
Search Spirit Airlines flights
DeltaPriceFrom $148Free CancellationRating
7.9
7,982 reviews
Search Delta flights
United AirlinesPriceFrom $188Free CancellationRating
7.4
8,995 reviews
Search United Airlines flights
American AirlinesPriceFrom $202Free CancellationRating
7.2
11,033 reviews
Search American Airlines flights
SouthwestPriceFrom $210Free CancellationRating
8.0
4,236 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

momondo helps you find the best flight between Chicago and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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