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Cheap flights from Chicago O'Hare Intl Airport to South Carolina from $60

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to South Carolina departing on 4/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:16 pm - 3:24 pm
ORD
-
CLT
2h 08mnonstop
Frontier Logo
4:40 pm - 6:14 pm
CLT
-
ORD
2h 34mnonstop
$132Frontier
Thu, Apr 30 - Mon, May 4
Multiple Airlines Logo
1:12 pm - 4:22 pm
ORD
-
CLT
2h 10mnonstop
Multiple Airlines Logo
12:50 pm - 12:24 am
CLT
-
ORD
12h 34m
1 stop
$133Multiple Airlines
Mon, Apr 20 - Thu, Apr 23
Spirit Airlines Logo
7:15 pm - 9:10 am
ORD
-
CLT
12h 55m
1 stop
Spirit Airlines Logo
12:48 pm - 11:56 pm
CLT
-
ORD
12h 08m
1 stop
$134Spirit Airlines
Mon, Apr 20 - Thu, May 7
Spirit Airlines Logo
7:15 pm - 9:10 am
ORD
-
CLT
12h 55m
1 stop
Spirit Airlines Logo
9:54 pm - 9:36 am
CLT
-
ORD
12h 42m
1 stop
$139Spirit Airlines
Mon, Apr 27 - Wed, Apr 29
Delta Logo
3:35 pm - 9:41 pm
ORD
-
AGS
5h 06m
1 stop
Delta Logo
7:00 am - 12:08 pm
AGS
-
ORD
6h 08m
1 stop
$177Delta
Tue, Aug 25 - Sat, Aug 29
Delta Logo
5:53 pm - 11:58 pm
ORD
-
AGS
5h 05m
1 stop
Delta Logo
6:17 pm - 11:59 pm
AGS
-
ORD
6h 42m
1 stop
$201Delta
Tue, Apr 21 - Mon, May 4
American Airlines Logo
5:00 am - 10:34 am
ORD
-
AGS
4h 34m
1 stop
American Airlines Logo
8:23 pm - 11:54 pm
AGS
-
ORD
4h 31m
1 stop
$225American Airlines
Sun, Apr 19 - Thu, Apr 23
American Airlines Logo
6:41 pm - 11:58 pm
ORD
-
AGS
4h 17m
1 stop
American Airlines Logo
8:23 pm - 11:54 pm
AGS
-
ORD
4h 31m
1 stop
$228American Airlines
Thu, Apr 30 - Sun, May 3
United Airlines Logo
10:45 am - 2:21 pm
ORD
-
HHH
2h 36mnonstop
United Airlines Logo
3:05 pm - 4:51 pm
HHH
-
ORD
2h 46mnonstop
$269United Airlines
Fri, Jun 26 - Tue, Jun 30
United Airlines Logo
9:05 am - 5:13 pm
ORD
-
MYR
7h 08m
1 stop
United Airlines Logo
11:30 am - 1:09 pm
MYR
-
ORD
2h 39mnonstop
$281United Airlines
Sat, May 2 - Thu, May 7

Frontier flights from Chicago O'Hare Intl Airport to South Carolina

Our best Frontier deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
Frontier
Apr 30
ORD1:27 pmChicago O'Hare Intl
23h 51m
1 stop
CLT2:18 pmCharlotte Douglas
May 4
CLT4:40 pmCharlotte Douglas
2h 34m
ORD6:14 pmChicago O'Hare Intl
$125
Frontier
Apr 30
ORD12:16 pmChicago O'Hare Intl
2h 08m
CLT3:24 pmCharlotte Douglas
May 4
CLT4:40 pmCharlotte Douglas
2h 34m
ORD6:14 pmChicago O'Hare Intl
$132
Frontier
Apr 27
ORD12:37 pmChicago O'Hare Intl
2h 08m
CLT3:45 pmCharlotte Douglas
May 2
CLT5:51 pmCharlotte Douglas
16h 54m
1 stop
ORD9:45 amChicago O'Hare Intl
$135

Spirit Airlines flights from Chicago O'Hare Intl Airport to South Carolina

Our best Spirit Airlines deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
Spirit Airlines
Apr 20
ORD7:15 pmChicago O'Hare Intl
12h 55m
1 stop
CLT9:10 amCharlotte Douglas
May 11
CLT12:48 pmCharlotte Douglas
12h 08m
1 stop
ORD11:56 pmChicago O'Hare Intl
$134
Spirit Airlines
Apr 21
ORD7:15 pmChicago O'Hare Intl
12h 55m
1 stop
CLT9:10 amCharlotte Douglas
Apr 23
CLT12:50 pmCharlotte Douglas
12h 34m
1 stop
ORD12:24 amChicago O'Hare Intl
$138
Spirit Airlines
Apr 27
ORD7:15 pmChicago O'Hare Intl
12h 55m
1 stop
CLT9:10 amCharlotte Douglas
Apr 29
CLT9:54 pmCharlotte Douglas
12h 42m
1 stop
ORD9:36 amChicago O'Hare Intl
$139

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 4/30

12:16 pm-3:24 pm

Nonstop2h 08m

Charlotte Douglas

Mon 5/4

4:40 pm-6:14 pm

Nonstop2h 34m

$132

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/20

1:12 pm-4:22 pm

Nonstop2h 10m

Charlotte Douglas

Thu 4/23

12:50 pm-12:24 am

1 stop12h 34m

$133

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/20

7:15 pm-9:10 am

1 stop12h 55m

Charlotte Douglas

Thu 5/7

12:48 pm-11:56 pm

1 stop12h 08m

$134

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/27

7:15 pm-9:10 am

1 stop12h 55m

Charlotte Douglas

Wed 4/29

9:54 pm-9:36 am

1 stop12h 42m

$139

ChicagoAugusta

ORD - AGS

ORDAGS

Chicago O'Hare Intl

Tue 8/25

3:35 pm-9:41 pm

1 stop5h 06m

Augusta Bush Field

Sat 8/29

7:00 am-12:08 pm

1 stop6h 08m

$177

ChicagoAugusta

ORD - AGS

ORDAGS

Chicago O'Hare Intl

Tue 4/21

5:53 pm-11:58 pm

1 stop5h 05m

Augusta Bush Field

Mon 5/4

6:17 pm-11:59 pm

1 stop6h 42m

$201

ChicagoAugusta

ORD - AGS

ORDAGS

Chicago O'Hare Intl

Sun 4/19

5:00 am-10:34 am

1 stop4h 34m

Augusta Bush Field

Thu 4/23

8:23 pm-11:54 pm

1 stop4h 31m

$225

ChicagoAugusta

ORD - AGS

ORDAGS

Chicago O'Hare Intl

Thu 4/30

6:41 pm-11:58 pm

1 stop4h 17m

Augusta Bush Field

Sun 5/3

8:23 pm-11:54 pm

1 stop4h 31m

$228

ChicagoHilton Head Island

ORD - HHH

ORDHHH

Chicago O'Hare Intl

Fri 6/26

10:45 am-2:21 pm

Nonstop2h 36m

Hilton Head Island

Tue 6/30

3:05 pm-4:51 pm

Nonstop2h 46m

$269

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sat 5/2

9:05 am-5:13 pm

1 stop7h 08m

Myrtle Beach Intl

Thu 5/7

11:30 am-1:09 pm

Nonstop2h 39m

$281

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago O'Hare Intl Airport is in August. Flight prices, which tend to average around $326, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Chicago O'Hare Intl Airport during September instead. Flights to South Carolina in September, while not as cheap as those in August, still average around $327.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $345. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $399.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago O'Hare Intl Airport to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $368. Try not to purchase tickets in the morning because they tend to be around $376. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago O'Hare Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago O'Hare Intl Airport for as low as $285 on momondo.

What cabin class options are available on Chicago O'Hare Intl to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to South Carolina flights?

You could potentially save up to 20% on your flight if you consider stops on a Chicago O'Hare Intl Airport to South Carolina flight.

Cheap Chicago O'Hare Intl Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to South Carolina

Best Price Found

$191

Fastest flight time

1h 56m

Direct flights

Every day

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Chicago O'Hare Intl Airport in the past 72 hours is $191. The best round-trip flight deal from Chicago O'Hare Intl Airport to South Carolina found on momondo in the last 72 hours is $280.
The fastest flight from Chicago O'Hare Intl Airport to South Carolina takes 1h 56m
Direct flights go from Chicago O'Hare Intl Airport to South Carolina every day.
There are 57 airports in South Carolina. From Chicago O'Hare Intl Airport there are direct flights to Greenville (GSP), Columbia Metropolitan (CAE), Charlotte Douglas (CLT).
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to South Carolina

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to South Carolina?

    Prices for flights from Chicago O'Hare Intl Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to South Carolina?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to South Carolina?

Best airlines flying from Chicago O'Hare Intl Airport to South Carolina

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $52Free CancellationRating
6.3
8,606 reviews
Search Spirit Airlines flights
DeltaPriceFrom $146Free CancellationRating
7.9
8,392 reviews
Search Delta flights
United AirlinesPriceFrom $186Free CancellationRating
7.4
9,555 reviews
Search United Airlines flights
American AirlinesPriceFrom $197Free CancellationRating
7.1
11,564 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

momondo helps you find the best flight between Chicago and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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