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Cheap flights from Chicago O'Hare Intl Airport to South Carolina from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to South Carolina departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to South Carolina

Cheap round-trip flights

Frontier Logo
7:40 am - 11:00 amORD-CLT
2h 20mnonstop
Frontier Logo
11:50 am - 1:12 pmCLT-ORD
2h 22mnonstop
$85Frontier
Find Deal
Thu, Sep 18 - Sun, Sep 21
Frontier Logo
11:32 am - 2:37 pmORD-CLT
2h 05mnonstop
Frontier Logo
3:25 pm - 4:47 pmCLT-ORD
2h 22mnonstop
$86Frontier
Find Deal
Thu, Nov 6 - Sun, Nov 16
Spirit Airlines Logo
10:12 am - 1:13 pmORD-MYR
2h 01mnonstop
Spirit Airlines Logo
2:18 pm - 3:43 pmMYR-ORD
2h 25mnonstop
$98Spirit Airlines
Find Deal
Thu, Aug 28 - Sun, Aug 31
Spirit Airlines Logo
10:12 am - 1:13 pmORD-MYR
2h 01mnonstop
Spirit Airlines Logo
2:40 pm - 11:59 pmMYR-ORD
10h 19m1 stop
$129Spirit Airlines
Find Deal
Sun, Aug 17 - Wed, Aug 20
American Airlines Logo
8:37 am - 11:42 amORD-CLT
2h 05mnonstop
American Airlines Logo
1:36 pm - 2:47 pmCLT-ORD
2h 11mnonstop
$134American Airlines
Find Deal
Sat, Sep 6 - Sat, Sep 6
American Airlines Logo
4:56 pm - 7:59 pmORD-CLT
2h 03mnonstop
American Airlines Logo
9:30 am - 10:55 amCLT-ORD
2h 25mnonstop
$139American Airlines
Find Deal
Sat, Oct 11 - Sat, Oct 18
United Airlines Logo
2:05 pm - 5:15 pmORD-CLT
2h 10mnonstop
United Airlines Logo
6:40 am - 8:00 amCLT-ORD
2h 20mnonstop
$141United Airlines
Find Deal
Thu, Sep 4 - Wed, Sep 10
United Airlines Logo
6:20 pm - 9:41 pmORD-CLT
2h 21mnonstop
United Airlines Logo
6:30 am - 7:50 amCLT-ORD
2h 20mnonstop
$143United Airlines
Find Deal
Fri, Sep 26 - Sun, Sep 28
Delta Logo
3:45 pm - 9:22 pmORD-CHS
4h 37m1 stop
Delta Logo
5:10 am - 8:40 amCHS-ORD
4h 30m1 stop
$201Delta
Find Deal
Sat, Sep 20 - Tue, Sep 23
Delta Logo
6:45 am - 1:50 pmORD-MYR
6h 05m1 stop
Delta Logo
12:20 pm - 7:25 pmMYR-ORD
8h 05m1 stop
$211Delta
Find Deal
Tue, Oct 7 - Sun, Oct 12

Spirit Airlines flights from Chicago O'Hare Intl Airport to South Carolina

Our best Spirit Airlines deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
Spirit Airlines
Aug 28
ORD10:12 amChicago O'Hare Intl
2h 01m
MYR1:13 pmMyrtle Beach Intl
Aug 31
MYR2:18 pmMyrtle Beach Intl
2h 25m
ORD3:43 pmChicago O'Hare Intl
$98
Find similar
Spirit Airlines
Aug 17
ORD10:12 amChicago O'Hare Intl
2h 01m
MYR1:13 pmMyrtle Beach Intl
Aug 20
MYR2:40 pmMyrtle Beach Intl
10h 19m
1 stop
ORD11:59 pmChicago O'Hare Intl
$129
Find similar
Spirit Airlines
Aug 28
ORD6:56 amChicago O'Hare Intl
11h 49m
1 stop
MYR7:45 pmMyrtle Beach Intl
Aug 31
MYR2:18 pmMyrtle Beach Intl
2h 25m
ORD3:43 pmChicago O'Hare Intl
$136
Find similar

American Airlines flights from Chicago O'Hare Intl Airport to South Carolina

Our best American Airlines deals on Chicago O'Hare Intl Airport to South Carolina flight tickets
American Airlines
Sep 6
ORD8:37 amChicago O'Hare Intl
2h 05m
CLT11:42 amCharlotte Douglas
Sep 6
CLT1:36 pmCharlotte Douglas
2h 11m
ORD2:47 pmChicago O'Hare Intl
$134
Find similar
American Airlines
Oct 11
ORD4:56 pmChicago O'Hare Intl
2h 03m
CLT7:59 pmCharlotte Douglas
Oct 18
CLT9:30 amCharlotte Douglas
2h 25m
ORD10:55 amChicago O'Hare Intl
$139
Find similar
American Airlines
Sep 16
ORD5:00 amChicago O'Hare Intl
2h 03m
CLT8:03 amCharlotte Douglas
Sep 23
CLT2:47 pmCharlotte Douglas
2h 10m
ORD3:57 pmChicago O'Hare Intl
$140
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 9/18

7:40 am-11:00 am

Nonstop2h 20m

Charlotte Douglas

Sun 9/21

11:50 am-1:12 pm

Nonstop2h 22m

$85

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 11/6

11:32 am-2:37 pm

Nonstop2h 05m

Charlotte Douglas

Sun 11/16

3:25 pm-4:47 pm

Nonstop2h 22m

$86

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 8/28

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

Sun 8/31

2:18 pm-3:43 pm

Nonstop2h 25m

$98

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sun 8/17

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

Wed 8/20

2:40 pm-11:59 pm

1 stop10h 19m

$129

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 9/6

8:37 am-11:42 am

Nonstop2h 05m

Charlotte Douglas

Sat 9/6

1:36 pm-2:47 pm

Nonstop2h 11m

$134

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 10/11

4:56 pm-7:59 pm

Nonstop2h 03m

Charlotte Douglas

Sat 10/18

9:30 am-10:55 am

Nonstop2h 25m

$139

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 9/4

2:05 pm-5:15 pm

Nonstop2h 10m

Charlotte Douglas

Wed 9/10

6:40 am-8:00 am

Nonstop2h 20m

$141

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 9/26

6:20 pm-9:41 pm

Nonstop2h 21m

Charlotte Douglas

Sun 9/28

6:30 am-7:50 am

Nonstop2h 20m

$143

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Sat 9/20

3:45 pm-9:22 pm

1 stop4h 37m

Charleston

Tue 9/23

5:10 am-8:40 am

1 stop4h 30m

$201

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 10/7

6:45 am-1:50 pm

1 stop6h 05m

Myrtle Beach Intl

Sun 10/12

12:20 pm-7:25 pm

1 stop8h 05m

$211

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago O'Hare Intl Airport is in August. Flight prices, which tend to average around $327, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Chicago O'Hare Intl Airport during September instead. Flights to South Carolina in September, while not as cheap as those in August, still average around $327.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $358. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $432.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago O'Hare Intl Airport to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $349. Try not to purchase tickets in the afternoon because they tend to be around $410. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago O'Hare Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago O'Hare Intl Airport for as low as $317 on momondo.

What cabin class options are available on Chicago O'Hare Intl to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to South Carolina.

Cheap Chicago O'Hare Intl Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to South Carolina

Best Price Found

$48

Fastest flight time

1h 46m

Direct flights

Every day

Airports in South Carolina

6 airports
The best one-way flight to South Carolina from Chicago O'Hare Intl Airport in the past 72 hours is $48. The best round-trip flight deal from Chicago O'Hare Intl Airport to South Carolina found on momondo in the last 72 hours is $85.
The fastest flight from Chicago O'Hare Intl Airport to South Carolina takes 1h 46m
Direct flights go from Chicago O'Hare Intl Airport to South Carolina every day.
There are 6 airports near South Carolina: Greenville (GSP), Columbia Metropolitan (CAE), Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)
Search flight deals

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to South Carolina?

    Prices for flights from Chicago O'Hare Intl Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to South Carolina?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to South Carolina?

Best airlines flying from Chicago O'Hare Intl Airport to South Carolina

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $55Free CancellationRating
6.3
8,053 reviews
Search Spirit Airlines flights
DeltaPriceFrom $149Free CancellationRating
8.0
7,987 reviews
Search Delta flights
United AirlinesPriceFrom $167Free CancellationRating
7.4
8,912 reviews
Search United Airlines flights
American AirlinesPriceFrom $188Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $216Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

momondo helps you find the best flight between Chicago and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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