Cheap flights from Chicago O'Hare Intl Airport to Myrtle Beach from $122

In general, September is the cheapest month to fly from Chicago O'Hare Intl Airport to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $376. If you are unable to visit Myrtle Beach during the month of September, then departing from Chicago O'Hare Intl Airport during the month August is also very affordable. Most momondo users find prices during this month for around $383.

Our data shows that Tuesday is the least expensive day to fly to Myrtle Beach. Tickets to fly out on this day can be as low as $344. The most expensive day to fly to Myrtle Beach is Sunday, with ticket prices averaging around $443.

The cheapest time of day to fly to Myrtle Beach is at noon when flights can be purchased for as low as $397. Flights in the evening are often more expensive with an average ticket price of $416.

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago O'Hare Intl - Myrtle Beach Intl flight prices

You are more likely to see cheaper flights to Myrtle Beach from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Myrtle Beach for around $424 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Myrtle Beach from Chicago O'Hare Intl Airport for as low as $334 on momondo.

There are 4 cabin classes available to choose from on Chicago O'Hare Intl Airport to Myrtle Beach flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Myrtle Beach.

As of November 2026, prices for Chicago O'Hare Intl Airport to Myrtle Beach flights are approximately 328% more expensive when compared to flights at the same time last year.

Delta and American Airlines are the most popular carriers operating from Chicago O'Hare Intl to Myrtle Beach Intl

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Myrtle Beach from Chicago O'Hare Intl Airport according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Myrtle Beach. Keep in mind that there are 3 different airlines that fly to Myrtle Beach on a routine basis, so you have a few additional options to choose from.

Historically, on average around 14% of flights between Chicago and Myrtle Beach have experienced a delay on any given week. The average delay length over the past 12 months has been 123 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, American Airlines have had the least number of delays on this route over the last 12 months; with about 11% of their flights experiencing any sort of delay.