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Cheap flights from North Carolina to Des Moines from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Des Moines departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from North Carolina to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:40 am - 2:05 pm
RDU
-
DSM
9h 25m
1 stop
Southwest Logo
3:45 pm - 9:05 pm
DSM
-
RDU
4h 20m
1 stop
$237Southwest
mié., jun. 3 - mar., jun. 9
Multiple Airlines Logo
6:15 am - 11:24 pm
RDU
-
DSM
18h 09m
2 stops
Multiple Airlines Logo
2:16 pm - 11:31 am
DSM
-
RDU
20h 15m
1 stop
$240Multiple Airlines
vie., may. 29 - lun., jun. 1
Southwest Logo
1:45 pm - 10:10 pm
RDU
-
DSM
9h 25m
2 stops
Southwest Logo
3:45 pm - 9:05 pm
DSM
-
RDU
4h 20m
1 stop
$242Southwest
mié., jun. 3 - mar., jun. 9
Multiple Airlines Logo
12:26 pm - 1:31 pm
RDU
-
DSM
26h 05m
1 stop
Multiple Airlines Logo
7:45 am - 5:08 pm
DSM
-
RDU
8h 23m
1 stop
$244Multiple Airlines
mar., may. 5 - jue., may. 7
Allegiant Air Logo
6:00 am - 10:06 pm
AVL
-
DSM
17h 06m
1 stop
Allegiant Air Logo
8:30 am - 10:33 pm
DSM
-
AVL
13h 03m
1 stop
$249Allegiant Air
jue., abr. 9 - dom., abr. 19
Allegiant Air Logo
6:00 am - 10:06 pm
AVL
-
DSM
17h 06m
1 stop
Allegiant Air Logo
2:03 pm - 11:15 pm
DSM
-
AVL
8h 12m
1 stop
$254Allegiant Air
jue., abr. 9 - lun., abr. 13
American Airlines Logo
5:45 am - 10:26 am
RDU
-
DSM
5h 41m
1 stop
American Airlines Logo
8:56 am - 3:14 pm
DSM
-
RDU
5h 18m
1 stop
$260American Airlines
lun., abr. 20 - mié., abr. 22
United Airlines Logo
3:02 pm - 11:24 pm
RDU
-
DSM
9h 22m
2 stops
United Airlines Logo
5:00 am - 10:46 am
DSM
-
RDU
4h 46m
1 stop
$265United Airlines
mar., may. 5 - sáb., may. 23
American Airlines Logo
6:00 am - 11:26 am
TYS
-
DSM
6h 26m
1 stop
American Airlines Logo
3:00 pm - 10:24 pm
DSM
-
TYS
6h 24m
1 stop
$302American Airlines
vie., may. 1 - lun., may. 4
United Airlines Logo
6:01 pm - 9:23 pm
TYS
-
DSM
4h 22m
1 stop
United Airlines Logo
5:00 am - 2:34 pm
DSM
-
TYS
8h 34m
2 stops
$323United Airlines
jue., may. 7 - dom., may. 10

Allegiant Air flights from North Carolina to Des Moines

Our best Allegiant Air deals on North Carolina to Des Moines flight tickets
Allegiant Air
Apr 9
AVL6:00 amAsheville Regional
17h 06m
1 stop
DSM10:06 pmDes Moines
Apr 19
DSM8:30 amDes Moines
13h 03m
1 stop
AVL10:33 pmAsheville Regional
$249
Allegiant Air
Apr 9
AVL6:00 amAsheville Regional
17h 06m
1 stop
DSM10:06 pmDes Moines
Apr 13
DSM2:03 pmDes Moines
8h 12m
1 stop
AVL11:15 pmAsheville Regional
$254
Allegiant Air
May 1
TYS8:30 amKnoxville McGhee Tyson
15h 12m
2 stops
DSM10:42 pmDes Moines
May 4
DSM2:59 pmDes Moines
22h 59m
1 stop
TYS2:58 pmKnoxville McGhee Tyson
$258

United Airlines flights from North Carolina to Des Moines

Our best United Airlines deals on North Carolina to Des Moines flight tickets
United Airlines
May 5
RDU3:02 pmRaleigh-Durham
9h 22m
2 stops
DSM11:24 pmDes Moines
May 23
DSM5:00 amDes Moines
4h 46m
1 stop
RDU10:46 amRaleigh-Durham
$265
United Airlines
Apr 18
RDU4:45 pmRaleigh-Durham
6h 58m
1 stop
DSM10:43 pmDes Moines
Apr 20
DSM1:10 pmDes Moines
7h 13m
1 stop
RDU9:23 pmRaleigh-Durham
$283
United Airlines
Apr 18
RDU3:02 pmRaleigh-Durham
9h 15m
2 stops
DSM11:17 pmDes Moines
Apr 20
DSM3:21 pmDes Moines
5h 02m
1 stop
RDU9:23 pmRaleigh-Durham
$288

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated marzo 28, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

mié. 6/3

5:40 am-2:05 pm

1 stop9h 25m

Des Moines

mar. 6/9

3:45 pm-9:05 pm

1 stop4h 20m

$237

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

vie. 5/29

6:15 am-11:24 pm

2 stops18h 09m

Des Moines

lun. 6/1

2:16 pm-11:31 am

1 stop20h 15m

$240

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

mié. 6/3

1:45 pm-10:10 pm

2 stops9h 25m

Des Moines

mar. 6/9

3:45 pm-9:05 pm

1 stop4h 20m

$242

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

mar. 5/5

12:26 pm-1:31 pm

1 stop26h 05m

Des Moines

jue. 5/7

7:45 am-5:08 pm

1 stop8h 23m

$244

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

jue. 4/9

6:00 am-10:06 pm

1 stop17h 06m

Des Moines

dom. 4/19

8:30 am-10:33 pm

1 stop13h 03m

$249

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

jue. 4/9

6:00 am-10:06 pm

1 stop17h 06m

Des Moines

lun. 4/13

2:03 pm-11:15 pm

1 stop8h 12m

$254
Quickest round-trip

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

lun. 4/20

5:45 am-10:26 am

1 stop5h 41m

Des Moines

mié. 4/22

8:56 am-3:14 pm

1 stop5h 18m

$260

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

mar. 5/5

3:02 pm-11:24 pm

2 stops9h 22m

Des Moines

sáb. 5/23

5:00 am-10:46 am

1 stop4h 46m

$265

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

vie. 5/1

6:00 am-11:26 am

1 stop6h 26m

Des Moines

lun. 5/4

3:00 pm-10:24 pm

1 stop6h 24m

$302

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

jue. 5/7

6:01 pm-9:23 pm

1 stop4h 22m

Des Moines

dom. 5/10

5:00 am-2:34 pm

2 stops8h 34m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from North Carolina to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then January is your next best option. Flight prices from North Carolina to Des Moines during January average around $346.

What is the cheapest North Carolina to Des Moines flight route?

Fly from Charlotte Douglas to Des Moines for the best North Carolina - Des Moines flight prices

What cabin class options are available on North Carolina to Des Moines flights?

There are 2 cabin classes available to choose from on North Carolina to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Des Moines flights?

You could potentially save up to 45% on your flight if you consider stops on a North Carolina to Des Moines flight.

Cheap North Carolina to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Des Moines

Best Price Found

$431

Fastest flight time

2h 30m

Direct flights

Every day

Airports in Des Moines

1 airport
The best flight deal from North Carolina to Des Moines found on momondo in the last 72 hours is $431
The fastest flight from North Carolina to Des Moines takes 2h 30m
Direct flights go from North Carolina to Des Moines every day.
There is 1 airport in Des Moines. From North Carolina there are direct flights to Des Moines (DSM).
Search flight deals

  • When did momondo last update prices for flights from North Carolina to Des Moines Airport?

    Prices for flights from North Carolina to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from North Carolina to Des Moines Airport?

  • How old do you have to be to fly from North Carolina to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from North Carolina to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from North Carolina to Des Moines?

Best airlines flying from North Carolina to Des Moines

Compare and see reviews for airlines that fly from North Carolina to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $242Free CancellationRating
7.1
11,520 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,499 reviews
Search United Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,356 reviews
Search Delta flights
SouthwestPriceFrom $335Free CancellationRating
8.0
4,333 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from North Carolina to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from North Carolina to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from North Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from North Carolina to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from North Carolina.

I’m not ready to book a flight from North Carolina to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from North Carolina and alert you when they change.

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lun. 4/27
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