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Cheap flights from Myrtle Beach to South America from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
2:46 pm - 12:56 amMYR-MDE
10h 10m1 stop
Spirit Airlines Logo
2:05 am - 5:48 pmMDE-MYR
15h 43m1 stop
$257Spirit Airlines
Find Deal
lun., dic. 1 - sáb., dic. 6
Spirit Airlines Logo
2:46 pm - 12:56 amMYR-MDE
10h 10m1 stop
Spirit Airlines Logo
11:50 am - 7:32 pmMDE-MYR
7h 42m1 stop
$315Spirit Airlines
Find Deal
lun., dic. 1 - dom., dic. 7
Multiple Airlines Logo
2:46 pm - 7:15 amMYR-BOG
16h 29m2 stops
Multiple Airlines Logo
2:17 am - 5:48 pmBOG-MYR
15h 31m1 stop
$355Multiple Airlines
Find Deal
lun., dic. 1 - dom., dic. 7
Multiple Airlines Logo
2:46 pm - 12:56 amMYR-MDE
10h 10m1 stop
Multiple Airlines Logo
1:23 pm - 5:48 pmMDE-MYR
28h 25m2 stops
$355Multiple Airlines
Find Deal
lun., dic. 1 - dom., dic. 7
Delta Logo
6:00 am - 2:33 pmMYR-BOG
9h 33m1 stop
Delta Logo
3:55 pm - 10:08 amBOG-MYR
17h 13m1 stop
$543Delta
Find Deal
mar., mar. 10 - vie., mar. 13
Delta Logo
6:00 am - 4:45 pmMYR-BOG
11h 45m2 stops
Delta Logo
3:55 pm - 10:08 amBOG-MYR
17h 13m1 stop
$548Delta
Find Deal
mar., mar. 10 - vie., mar. 13
LATAM Airlines Logo
6:00 am - 4:45 pmMYR-BOG
11h 45m2 stops
LATAM Airlines Logo
7:00 am - 11:35 pmBOG-MYR
15h 35m2 stops
$564LATAM Airlines
Find Deal
mar., mar. 10 - vie., mar. 13
LATAM Airlines Logo
6:00 am - 6:40 pmMYR-BOG
13h 40m2 stops
LATAM Airlines Logo
7:00 am - 5:56 pmBOG-MYR
9h 56m2 stops
$611LATAM Airlines
Find Deal
mar., mar. 10 - vie., mar. 13
American Airlines Logo
8:41 pm - 12:35 pmMYR-MDE
16h 54m2 stops
American Airlines Logo
12:20 am - 7:07 pmMDE-MYR
17h 47m2 stops
$617American Airlines
Find Deal
sáb., mar. 21 - sáb., mar. 28
American Airlines Logo
6:52 am - 9:10 pmMYR-MDE
14h 18m2 stops
American Airlines Logo
7:00 am - 10:10 amMDE-MYR
27h 10m2 stops
$726American Airlines
Find Deal
mar., mar. 3 - vie., mar. 6

Delta flights from Myrtle Beach to South America

Our best Delta deals on Myrtle Beach to South America flight tickets
Delta
Mar 10
MYR6:00 amMyrtle Beach Intl
9h 33m
1 stop
BOG2:33 pmBogotá El Dorado
Mar 13
BOG3:55 pmBogotá El Dorado
17h 13m
1 stop
MYR10:08 amMyrtle Beach Intl
$543
Find similar
Delta
Mar 10
MYR6:00 amMyrtle Beach Intl
11h 45m
2 stops
BOG4:45 pmBogotá El Dorado
Mar 13
BOG3:55 pmBogotá El Dorado
17h 13m
1 stop
MYR10:08 amMyrtle Beach Intl
$548
Find similar
Delta
Oct 29
MYR6:58 pmMyrtle Beach Intl
18h 07m
2 stops
BOG12:05 pmBogotá El Dorado
Nov 4
BOG5:15 pmBogotá El Dorado
16h 36m
2 stops
MYR9:51 amMyrtle Beach Intl
$603
Find similar

Spirit Airlines flights from Myrtle Beach to South America

Our best Spirit Airlines deals on Myrtle Beach to South America flight tickets
Spirit Airlines
Dec 1
MYR2:46 pmMyrtle Beach Intl
10h 10m
1 stop
MDE12:56 amMedellín Jose Maria Cordova Intl
Dec 6
MDE2:05 amMedellín Jose Maria Cordova Intl
15h 43m
1 stop
MYR5:48 pmMyrtle Beach Intl
$257
Find similar
Spirit Airlines
Dec 1
MYR2:46 pmMyrtle Beach Intl
10h 10m
1 stop
MDE12:56 amMedellín Jose Maria Cordova Intl
Dec 7
MDE11:50 amMedellín Jose Maria Cordova Intl
7h 42m
1 stop
MYR7:32 pmMyrtle Beach Intl
$315
Find similar
Spirit Airlines
Dec 1
MYR2:46 pmMyrtle Beach Intl
10h 10m
1 stop
MDE12:56 amMedellín Jose Maria Cordova Intl
Dec 6
MDE2:05 amMedellín Jose Maria Cordova Intl
17h 27m
2 stops
MYR7:32 pmMyrtle Beach Intl
$335
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

lun. 12/1

2:46 pm-12:56 am

1 stop10h 10m

Medellín Jose Maria Cordova Intl

sáb. 12/6

2:05 am-5:48 pm

1 stop15h 43m

$257

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

lun. 12/1

2:46 pm-12:56 am

1 stop10h 10m

Medellín Jose Maria Cordova Intl

dom. 12/7

11:50 am-7:32 pm

1 stop7h 42m

$315

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

lun. 12/1

2:46 pm-7:15 am

2 stops16h 29m

Bogotá El Dorado

dom. 12/7

2:17 am-5:48 pm

1 stop15h 31m

$355

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

lun. 12/1

2:46 pm-12:56 am

1 stop10h 10m

Medellín Jose Maria Cordova Intl

dom. 12/7

1:23 pm-5:48 pm

2 stops28h 25m

$355

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

mar. 3/10

6:00 am-2:33 pm

1 stop9h 33m

Bogotá El Dorado

vie. 3/13

3:55 pm-10:08 am

1 stop17h 13m

$543

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

mar. 3/10

6:00 am-4:45 pm

2 stops11h 45m

Bogotá El Dorado

vie. 3/13

3:55 pm-10:08 am

1 stop17h 13m

$548

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

mar. 3/10

6:00 am-4:45 pm

2 stops11h 45m

Bogotá El Dorado

vie. 3/13

7:00 am-11:35 pm

2 stops15h 35m

$564

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

mar. 3/10

6:00 am-6:40 pm

2 stops13h 40m

Bogotá El Dorado

vie. 3/13

7:00 am-5:56 pm

2 stops9h 56m

$611

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

sáb. 3/21

8:41 pm-12:35 pm

2 stops16h 54m

Medellín Jose Maria Cordova Intl

sáb. 3/28

12:20 am-7:07 pm

2 stops17h 47m

$617

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

mar. 3/3

6:52 am-9:10 pm

2 stops14h 18m

Medellín Jose Maria Cordova Intl

vie. 3/6

7:00 am-10:10 am

2 stops27h 10m

$726

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Myrtle Beach to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $844. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $853 on average. Flights to South America from Myrtle Beach in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Myrtle Beach to South America flights?

You could potentially save up to 62% on your flight if you consider stops on a Myrtle Beach to South America flight.

Cheap Myrtle Beach to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to South America

Direct flights

None
There are no direct flights from Myrtle Beach to South America. There are no popular flight routes from Myrtle Beach to South America.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to South America?

    Prices for flights from Myrtle Beach Intl Airport to South America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to South America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to South America

Compare and see reviews for airlines that fly from Myrtle Beach to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,116 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $593Free CancellationRating
7.5
1,871 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to South America?

It is quick and easy to find Myrtle Beach to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Myrtle Beach to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to South America?

momondo provides multiple filters to help you find the best flight to South America from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South America trip

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