Cheap flights from Myrtle Beach to South America from $166

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
6:28 pm - 12:06 pm
MYR
-
CTG
18h 38m
1 stop
Spirit Airlines Logo
1:11 pm - 11:29 pm
CTG
-
MYR
9h 18m
1 stop
$320Spirit Airlines
Fri, Apr 10 - Fri, Apr 17
Multiple Airlines Logo
11:52 am - 9:25 pm
MYR
-
MDE
10h 33m
1 stop
Multiple Airlines Logo
9:45 am - 8:58 pm
MDE
-
MYR
34h 13m
2 stops
$457Multiple Airlines
Wed, May 13 - Sat, May 23
Multiple Airlines Logo
11:52 am - 9:25 pm
MYR
-
MDE
10h 33m
1 stop
Multiple Airlines Logo
11:37 pm - 7:33 pm
MDE
-
MYR
42h 56m
2 stops
$469Multiple Airlines
Wed, May 13 - Sun, May 24
Delta Logo
6:00 am - 8:05 am
MYR
-
LIM
27h 05m
2 stops
Delta Logo
12:10 am - 11:39 pm
LIM
-
MYR
22h 29m
2 stops
$665Delta
Wed, Sep 2 - Tue, Sep 8
Delta Logo
6:45 pm - 5:00 am
MYR
-
LIM
11h 15m
1 stop
Delta Logo
12:15 am - 6:00 pm
LIM
-
MYR
16h 45m
2 stops
$670Delta
Tue, Sep 1 - Tue, Sep 8
United Airlines Logo
11:57 am - 10:00 pm
MYR
-
BOG
11h 03m
1 stop
United Airlines Logo
8:30 am - 2:17 pm
BOG
-
MYR
28h 47m
2 stops
$709United Airlines
Fri, Apr 10 - Mon, Apr 13
United Airlines Logo
3:15 pm - 7:20 pm
MYR
-
BOG
29h 05m
2 stops
United Airlines Logo
8:30 am - 10:18 am
BOG
-
MYR
24h 48m
2 stops
$728United Airlines
Fri, Apr 10 - Mon, Apr 13
LATAM Airlines Logo
6:00 am - 6:45 pm
MYR
-
BOG
13h 45m
2 stops
LATAM Airlines Logo
11:00 am - 12:14 am
BOG
-
MYR
12h 14m
2 stops
$743LATAM Airlines
Fri, Apr 10 - Mon, Apr 13
LATAM Airlines Logo
10:23 am - 7:15 pm
MYR
-
BOG
9h 52m
1 stop
LATAM Airlines Logo
2:55 pm - 9:40 am
BOG
-
MYR
17h 45m
1 stop
$748LATAM Airlines
Fri, Apr 10 - Mon, Apr 13
American Airlines Logo
9:14 am - 7:05 am
MYR
-
SCL
21h 51m
2 stops
American Airlines Logo
8:35 pm - 3:39 pm
SCL
-
MYR
19h 04m
2 stops
$925American Airlines
Wed, May 6 - Wed, May 13

United Airlines flights from Myrtle Beach to South America

Our best United Airlines deals on Myrtle Beach to South America flight tickets
United Airlines
May 4
MYR3:14 pmMyrtle Beach Intl
30h 56m
2 stops
MDE9:10 pmMedellín Jose Maria Cordova Intl
May 7
MDE9:45 amMedellín Jose Maria Cordova Intl
51h 33m
2 stops
MYR2:18 pmMyrtle Beach Intl
$694
United Airlines
Apr 10
MYR11:57 amMyrtle Beach Intl
11h 03m
1 stop
BOG10:00 pmBogotá El Dorado
Apr 13
BOG8:30 amBogotá El Dorado
28h 47m
2 stops
MYR2:17 pmMyrtle Beach Intl
$709
United Airlines
Apr 10
MYR3:15 pmMyrtle Beach Intl
29h 05m
2 stops
BOG7:20 pmBogotá El Dorado
Apr 13
BOG8:30 amBogotá El Dorado
24h 48m
2 stops
MYR10:18 amMyrtle Beach Intl
$728

LATAM Airlines flights from Myrtle Beach to South America

Our best LATAM Airlines deals on Myrtle Beach to South America flight tickets
LATAM Airlines
Apr 10
MYR6:00 amMyrtle Beach Intl
13h 45m
2 stops
BOG6:45 pmBogotá El Dorado
Apr 13
BOG11:00 amBogotá El Dorado
12h 14m
2 stops
MYR12:14 amMyrtle Beach Intl
$743
LATAM Airlines
Jun 15
MYR6:00 amMyrtle Beach Intl
16h 40m
2 stops
LIM9:40 pmLima J Chavez Intl
Jun 25
LIM12:10 amLima J Chavez Intl
32h 59m
2 stops
MYR10:09 amMyrtle Beach Intl
$745
LATAM Airlines
Apr 10
MYR10:23 amMyrtle Beach Intl
9h 52m
1 stop
BOG7:15 pmBogotá El Dorado
Apr 13
BOG2:55 pmBogotá El Dorado
17h 45m
1 stop
MYR9:40 amMyrtle Beach Intl
$748

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

Fri 4/10

6:28 pm-12:06 pm

1 stop18h 38m

Cartagena Rafael Nunez

Fri 4/17

1:11 pm-11:29 pm

1 stop9h 18m

$320

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Wed 5/13

11:52 am-9:25 pm

1 stop10h 33m

Medellín Jose Maria Cordova Intl

Sat 5/23

9:45 am-8:58 pm

2 stops34h 13m

$457

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Wed 5/13

11:52 am-9:25 pm

1 stop10h 33m

Medellín Jose Maria Cordova Intl

Sun 5/24

11:37 pm-7:33 pm

2 stops42h 56m

$469

Myrtle BeachLima

MYR - LIM

MYRLIM

Myrtle Beach Intl

Wed 9/2

6:00 am-8:05 am

2 stops27h 05m

Lima J Chavez Intl

Tue 9/8

12:10 am-11:39 pm

2 stops22h 29m

$665

Myrtle BeachLima

MYR - LIM

MYRLIM

Myrtle Beach Intl

Tue 9/1

6:45 pm-5:00 am

1 stop11h 15m

Lima J Chavez Intl

Tue 9/8

12:15 am-6:00 pm

2 stops16h 45m

$670

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 4/10

11:57 am-10:00 pm

1 stop11h 03m

Bogotá El Dorado

Mon 4/13

8:30 am-2:17 pm

2 stops28h 47m

$709

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 4/10

3:15 pm-7:20 pm

2 stops29h 05m

Bogotá El Dorado

Mon 4/13

8:30 am-10:18 am

2 stops24h 48m

$728
Quickest round-trip

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 4/10

6:00 am-6:45 pm

2 stops13h 45m

Bogotá El Dorado

Mon 4/13

11:00 am-12:14 am

2 stops12h 14m

$743

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 4/10

10:23 am-7:15 pm

1 stop9h 52m

Bogotá El Dorado

Mon 4/13

2:55 pm-9:40 am

1 stop17h 45m

$748

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Wed 5/6

9:14 am-7:05 am

2 stops21h 51m

Santiago Arturo Merino Benitez

Wed 5/13

8:35 pm-3:39 pm

2 stops19h 04m

$925

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to South America flights?

You could potentially save up to 26% on your flight if you consider stops on a Myrtle Beach to South America flight.

Cheap Myrtle Beach to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to South America

Fastest flight time

8h 20m

Direct flights

None
The fastest flight from Myrtle Beach to South America takes 8h 20m
There are no direct flights from Myrtle Beach to South America. There are no popular flight routes from Myrtle Beach to South America.
  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to South America?

    Prices for flights from Myrtle Beach Intl Airport to South America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to South America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to South America

Compare and see reviews for airlines that fly from Myrtle Beach to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,538 reviews
Search Spirit Airlines flights
DeltaPriceFrom $555Free CancellationRating
7.9
8,319 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to South America?

It is quick and easy to find Myrtle Beach to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Myrtle Beach to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to South America?

momondo provides multiple filters to help you find the best flight to South America from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Wed 4/22
Wed 4/29

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