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Cheap flights from Myrtle Beach to South America from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to South America

Cheap round-trip flights

Spirit Airlines Logo
9:05 pm - 2:11 pmMYR-MDE
17h 06m1 stop
Spirit Airlines Logo
6:59 pm - 10:41 amMDE-MYR
15h 42m1 stop
$331Spirit Airlines
Find Deal
Mon, Nov 3 - Tue, Nov 11
Spirit Airlines Logo
9:05 pm - 1:11 pmMYR-MDE
17h 06m1 stop
Spirit Airlines Logo
1:12 am - 8:04 pmMDE-MYR
17h 52m1 stop
$358Spirit Airlines
Find Deal
Sun, Oct 19 - Sat, Oct 25
Logo
7:36 pm - 5:59 pmMYR-BOG
23h 23m1 stop
Logo
9:15 am - 10:41 amBOG-MYR
25h 26m1 stop
$407
Find Deal
Wed, Sep 24 - Wed, Nov 5
Logo
4:23 pm - 8:05 amMYR-BOG
16h 42m2 stops
Logo
3:05 pm - 10:41 amBOG-MYR
19h 36m1 stop
$426
Find Deal
Sat, Sep 27 - Wed, Nov 5
American Airlines Logo
6:23 am - 9:10 pmMYR-MDE
14h 47m2 stops
American Airlines Logo
7:00 am - 8:49 pmMDE-MYR
13h 49m2 stops
$531American Airlines
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Mon, Nov 3 - Tue, Nov 11
Delta Logo
2:35 pm - 12:00 pmMYR-BOG
22h 25m2 stops
Delta Logo
5:00 am - 11:35 pmBOG-MYR
18h 35m2 stops
$559Delta
Find Deal
Fri, Oct 24 - Wed, Jan 14
Delta Logo
6:00 am - 1:40 pmMYR-BOG
8h 40m1 stop
Delta Logo
1:35 am - 11:35 pmBOG-MYR
22h 00m2 stops
$563Delta
Find Deal
Fri, Oct 24 - Tue, Jan 13
LATAM Airlines Logo
6:00 am - 6:59 pmMYR-UIO
13h 59m1 stop
LATAM Airlines Logo
12:59 am - 6:03 pmUIO-MYR
16h 04m1 stop
$564LATAM Airlines
Find Deal
Thu, Oct 9 - Sun, Oct 19
American Airlines Logo
6:33 pm - 3:05 pmMYR-CTG
20h 32m2 stops
American Airlines Logo
4:55 pm - 2:10 pmCTG-MYR
21h 15m2 stops
$567American Airlines
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Sat, Jan 10 - Thu, Jan 15
LATAM Airlines Logo
6:00 am - 6:59 pmMYR-UIO
13h 59m1 stop
LATAM Airlines Logo
9:01 am - 1:50 pmUIO-MYR
27h 49m2 stops
$601LATAM Airlines
Find Deal
Thu, Oct 9 - Mon, Oct 20

Delta flights from Myrtle Beach to South America

Our best Delta deals on Myrtle Beach to South America flight tickets
Delta
Oct 24
MYR2:35 pmMyrtle Beach Intl
22h 25m
2 stops
BOG12:00 pmBogotá El Dorado
Jan 14
BOG5:00 amBogotá El Dorado
18h 35m
2 stops
MYR11:35 pmMyrtle Beach Intl
$559
Find similar
Delta
Oct 24
MYR6:00 amMyrtle Beach Intl
8h 40m
1 stop
BOG1:40 pmBogotá El Dorado
Jan 13
BOG1:35 amBogotá El Dorado
22h 00m
2 stops
MYR11:35 pmMyrtle Beach Intl
$563
Find similar
Delta
Oct 7
MYR2:35 pmMyrtle Beach Intl
22h 25m
2 stops
BOG12:00 pmBogotá El Dorado
Nov 17
BOG1:35 amBogotá El Dorado
16h 20m
2 stops
MYR5:55 pmMyrtle Beach Intl
$567
Find similar

Spirit Airlines flights from Myrtle Beach to South America

Our best Spirit Airlines deals on Myrtle Beach to South America flight tickets
Spirit Airlines
Nov 3
MYR9:05 pmMyrtle Beach Intl
17h 06m
1 stop
MDE2:11 pmMedellín Jose Maria Cordova Intl
Nov 11
MDE6:59 pmMedellín Jose Maria Cordova Intl
15h 42m
1 stop
MYR10:41 amMyrtle Beach Intl
$331
Find similar
Spirit Airlines
Oct 19
MYR9:05 pmMyrtle Beach Intl
17h 06m
1 stop
MDE1:11 pmMedellín Jose Maria Cordova Intl
Oct 25
MDE1:12 amMedellín Jose Maria Cordova Intl
17h 52m
1 stop
MYR8:04 pmMyrtle Beach Intl
$358
Find similar
Spirit Airlines
Nov 1
MYR10:26 amMyrtle Beach Intl
28h 27m
1 stop
AXM1:53 pmArmenia El Eden
Nov 10
AXM2:44 pmArmenia El Eden
19h 57m
1 stop
MYR10:41 amMyrtle Beach Intl
$373
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momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Mon 11/3

9:05 pm-2:11 pm

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Tue 11/11

6:59 pm-10:41 am

1 stop15h 42m

$331

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Sun 10/19

9:05 pm-1:11 pm

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Sat 10/25

1:12 am-8:04 pm

1 stop17h 52m

$358

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Wed 9/24

7:36 pm-5:59 pm

1 stop23h 23m

Bogotá El Dorado

Wed 11/5

9:15 am-10:41 am

1 stop25h 26m

$407

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Sat 9/27

4:23 pm-8:05 am

2 stops16h 42m

Bogotá El Dorado

Wed 11/5

3:05 pm-10:41 am

1 stop19h 36m

$426

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Mon 11/3

6:23 am-9:10 pm

2 stops14h 47m

Medellín Jose Maria Cordova Intl

Tue 11/11

7:00 am-8:49 pm

2 stops13h 49m

$531

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 10/24

2:35 pm-12:00 pm

2 stops22h 25m

Bogotá El Dorado

Wed 1/14

5:00 am-11:35 pm

2 stops18h 35m

$559

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Fri 10/24

6:00 am-1:40 pm

1 stop8h 40m

Bogotá El Dorado

Tue 1/13

1:35 am-11:35 pm

2 stops22h 00m

$563

Myrtle BeachQuito

MYR - UIO

MYRUIO

Myrtle Beach Intl

Thu 10/9

6:00 am-6:59 pm

1 stop13h 59m

Quito Mariscal Sucr

Sun 10/19

12:59 am-6:03 pm

1 stop16h 04m

$564

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

Sat 1/10

6:33 pm-3:05 pm

2 stops20h 32m

Cartagena Rafael Nunez

Thu 1/15

4:55 pm-2:10 pm

2 stops21h 15m

$567

Myrtle BeachQuito

MYR - UIO

MYRUIO

Myrtle Beach Intl

Thu 10/9

6:00 am-6:59 pm

1 stop13h 59m

Quito Mariscal Sucr

Mon 10/20

9:01 am-1:50 pm

2 stops27h 49m

$601

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Myrtle Beach to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $844. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $853 on average. Flights to South America from Myrtle Beach in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Myrtle Beach to South America flights?

You could potentially save up to 77% on your flight if you consider stops on a Myrtle Beach to South America flight.

Cheap Myrtle Beach to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to South America

Direct flights

None
There are no direct flights from Myrtle Beach to South America. There are no popular flight routes from Myrtle Beach to South America.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to South America?

    Prices for flights from Myrtle Beach Intl Airport to South America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to South America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to South America

Compare and see reviews for airlines that fly from Myrtle Beach to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $333Free CancellationRating
6.3
8,016 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $593Free CancellationRating
7.5
1,846 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to South America?

It is quick and easy to find Myrtle Beach to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Myrtle Beach to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to South America?

momondo provides multiple filters to help you find the best flight to South America from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South America trip

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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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