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Cheap flights from Myrtle Beach to South America from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
9:10 am - 2:13 pm
MYR
-
MDE
29h 03m1 stop
Spirit Airlines Logo
3:10 pm - 8:15 am
MDE
-
MYR
17h 05m1 stop
$315Spirit Airlines
qui, fev 19 - seg, fev 23
Spirit Airlines Logo
8:15 pm - 2:15 pm
MYR
-
MDE
18h 00m1 stop
Spirit Airlines Logo
3:15 pm - 7:20 pm
MDE
-
MYR
28h 05m1 stop
$318Spirit Airlines
qui, fev 5 - seg, fev 9
Spirit Airlines Logo
8:15 pm - 1:15 pm
MYR
-
CTG
17h 00m1 stop
Spirit Airlines Logo
2:21 pm - 7:20 pm
CTG
-
MYR
28h 59m1 stop
$331Spirit Airlines
sex, jan 23 - sex, jan 30
Multiple Airlines Logo
8:15 pm - 6:10 pm
MYR
-
BOG
21h 55m1 stop
Multiple Airlines Logo
9:15 am - 7:20 pm
BOG
-
MYR
10h 05m1 stop
$414Multiple Airlines
sex, jan 23 - sex, jan 30
Multiple Airlines Logo
9:10 am - 6:10 pm
MYR
-
BOG
10h 00m1 stop
Multiple Airlines Logo
9:15 am - 5:39 pm
BOG
-
MYR
7h 24m1 stop
$461Multiple Airlines
ter, mar 10 - seg, mar 16
Delta Logo
2:19 pm - 1:45 pm
MYR
-
BOG
24h 26m2 stops
Delta Logo
6:15 am - 11:59 pm
BOG
-
MYR
16h 44m2 stops
$513Delta
ter, mar 10 - seg, mar 16
United Airlines Logo
3:25 pm - 11:25 pm
MYR
-
UIO
33h 00m2 stops
United Airlines Logo
12:35 am - 2:37 pm
UIO
-
MYR
13h 02m2 stops
$586United Airlines
seg, abr 6 - dom, abr 12
United Airlines Logo
3:25 pm - 11:25 pm
MYR
-
UIO
33h 00m2 stops
United Airlines Logo
12:35 am - 2:37 pm
UIO
-
MYR
37h 02m2 stops
$593United Airlines
seg, abr 6 - qua, abr 15
LATAM Airlines Logo
6:00 am - 11:55 pm
MYR
-
CLO
17h 55m2 stops
LATAM Airlines Logo
10:45 pm - 11:41 pm
CLO
-
MYR
24h 56m2 stops
$792LATAM Airlines
sáb, jan 31 - ter, fev 3
LATAM Airlines Logo
6:00 am - 10:10 pm
MYR
-
CLO
16h 10m2 stops
LATAM Airlines Logo
10:15 pm - 11:41 pm
CLO
-
MYR
25h 26m2 stops
$829LATAM Airlines
sáb, jan 31 - ter, fev 3

Spirit Airlines flights from Myrtle Beach to South America

Our best Spirit Airlines deals on Myrtle Beach to South America flight tickets
Spirit Airlines
Feb 19
MYR9:10 amMyrtle Beach Intl
29h 03m
1 stop
MDE2:13 pmMedellín Jose Maria Cordova Intl
Feb 23
MDE3:10 pmMedellín Jose Maria Cordova Intl
17h 05m
1 stop
MYR8:15 amMyrtle Beach Intl
$315
Find similar
Spirit Airlines
Feb 5
MYR8:15 pmMyrtle Beach Intl
18h 00m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 9
MDE3:15 pmMedellín Jose Maria Cordova Intl
28h 05m
1 stop
MYR7:20 pmMyrtle Beach Intl
$318
Find similar
Spirit Airlines
Feb 1
MYR8:15 pmMyrtle Beach Intl
17h 52m
1 stop
BOG2:07 pmBogotá El Dorado
Feb 7
BOG3:06 pmBogotá El Dorado
28h 14m
1 stop
MYR7:20 pmMyrtle Beach Intl
$338
Find similar

Delta flights from Myrtle Beach to South America

Our best Delta deals on Myrtle Beach to South America flight tickets
Delta
Mar 10
MYR2:19 pmMyrtle Beach Intl
24h 26m
2 stops
BOG1:45 pmBogotá El Dorado
Mar 16
BOG6:15 amBogotá El Dorado
16h 44m
2 stops
MYR11:59 pmMyrtle Beach Intl
$513
Find similar
Delta
Mar 17
MYR2:19 pmMyrtle Beach Intl
15h 41m
1 stop
LIM5:00 amLima J Chavez Intl
Mar 25
LIM12:15 pmLima J Chavez Intl
20h 23m
1 stop
MYR9:38 amMyrtle Beach Intl
$594
Find similar
Delta
Mar 15
MYR10:23 amMyrtle Beach Intl
19h 37m
2 stops
LIM5:00 amLima J Chavez Intl
Mar 24
LIM12:15 pmLima J Chavez Intl
10h 44m
1 stop
MYR11:59 pmMyrtle Beach Intl
$599
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated dezembro 11, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

qui 2/19

9:10 am-2:13 pm

1 stop29h 03m

Medellín Jose Maria Cordova Intl

seg 2/23

3:10 pm-8:15 am

1 stop17h 05m

$315

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

qui 2/5

8:15 pm-2:15 pm

1 stop18h 00m

Medellín Jose Maria Cordova Intl

seg 2/9

3:15 pm-7:20 pm

1 stop28h 05m

$318

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

sex 1/23

8:15 pm-1:15 pm

1 stop17h 00m

Cartagena Rafael Nunez

sex 1/30

2:21 pm-7:20 pm

1 stop28h 59m

$331

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

sex 1/23

8:15 pm-6:10 pm

1 stop21h 55m

Bogotá El Dorado

sex 1/30

9:15 am-7:20 pm

1 stop10h 05m

$414

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

ter 3/10

9:10 am-6:10 pm

1 stop10h 00m

Bogotá El Dorado

seg 3/16

9:15 am-5:39 pm

1 stop7h 24m

$461

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

ter 3/10

2:19 pm-1:45 pm

2 stops24h 26m

Bogotá El Dorado

seg 3/16

6:15 am-11:59 pm

2 stops16h 44m

$513

Myrtle BeachQuito

MYR - UIO

MYRUIO

Myrtle Beach Intl

seg 4/6

3:25 pm-11:25 pm

2 stops33h 00m

Quito Mariscal Sucr

dom 4/12

12:35 am-2:37 pm

2 stops13h 02m

$586

Myrtle BeachQuito

MYR - UIO

MYRUIO

Myrtle Beach Intl

seg 4/6

3:25 pm-11:25 pm

2 stops33h 00m

Quito Mariscal Sucr

qua 4/15

12:35 am-2:37 pm

2 stops37h 02m

$593

Myrtle BeachCali

MYR - CLO

MYRCLO

Myrtle Beach Intl

sáb 1/31

6:00 am-11:55 pm

2 stops17h 55m

Cali Alfonso B. Aragon Intl

ter 2/3

10:45 pm-11:41 pm

2 stops24h 56m

$792

Myrtle BeachCali

MYR - CLO

MYRCLO

Myrtle Beach Intl

sáb 1/31

6:00 am-10:10 pm

2 stops16h 10m

Cali Alfonso B. Aragon Intl

ter 2/3

10:15 pm-11:41 pm

2 stops25h 26m

$829

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Myrtle Beach to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $844. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $853 on average. Flights to South America from Myrtle Beach in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Myrtle Beach to South America flights?

You could potentially save up to 27% on your flight if you consider stops on a Myrtle Beach to South America flight.

Cheap Myrtle Beach to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to South America

Fastest flight time

10h 00m

Direct flights

None
The fastest flight from Myrtle Beach to South America takes 10h 00m
There are no direct flights from Myrtle Beach to South America. There are no popular flight routes from Myrtle Beach to South America.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to South America?

    Prices for flights from Myrtle Beach Intl Airport to South America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to South America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to South America

Compare and see reviews for airlines that fly from Myrtle Beach to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,180 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $593Free CancellationRating
7.5
1,887 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to South America?

It is quick and easy to find Myrtle Beach to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Myrtle Beach to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to South America?

momondo provides multiple filters to help you find the best flight to South America from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South America trip

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sáb 1/10
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Find better results for your trip to South America

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