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Cheap flights from Myrtle Beach to Medellín from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Medellín departing on 12/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
9:54 am - 1:28 am
MYR
-
MDE
15h 34m1 stop
Spirit Airlines Logo
3:15 pm - 7:20 pm
MDE
-
MYR
28h 05m1 stop
$388Spirit Airlines
Fri, Jan 2 - Sat, Jan 17
Multiple Airlines Logo
9:54 am - 1:28 am
MYR
-
MDE
15h 34m1 stop
Multiple Airlines Logo
8:37 am - 7:20 pm
MDE
-
MYR
10h 43m2 stops
$456Multiple Airlines
Fri, Jan 2 - Sat, Jan 17
Spirit Airlines Logo
9:54 am - 1:28 am
MYR
-
MDE
15h 34m1 stop
Spirit Airlines Logo
2:50 pm - 7:20 pm
MDE
-
MYR
28h 30m3 stops
$513Spirit Airlines
Fri, Jan 2 - Sat, Jan 17
Spirit Airlines Logo
6:00 am - 1:28 am
MYR
-
MDE
19h 28m3 stops
Spirit Airlines Logo
3:15 pm - 12:12 pm
MDE
-
MYR
20h 57m2 stops
$527Spirit Airlines
Fri, Jan 2 - Sat, Jan 17
American Airlines Logo
9:04 am - 9:10 pm
MYR
-
MDE
12h 06m2 stops
American Airlines Logo
2:15 pm - 10:01 am
MDE
-
MYR
18h 46m2 stops
$532American Airlines
Sun, Mar 1 - Sat, Mar 21
Spirit Airlines Logo
9:54 am - 1:28 am
MYR
-
MDE
15h 34m1 stop
Spirit Airlines Logo
2:25 am - 6:08 pm
MDE
-
MYR
15h 43m1 stop
$547Spirit Airlines
Tue, Dec 30 - Mon, Jan 5
Spirit Airlines Logo
9:54 am - 1:28 am
MYR
-
MDE
15h 34m1 stop
Spirit Airlines Logo
2:54 pm - 6:08 pm
MDE
-
MYR
27h 14m2 stops
$550Spirit Airlines
Tue, Dec 30 - Tue, Jan 6
American Airlines Logo
7:56 pm - 2:06 pm
MYR
-
MDE
18h 10m2 stops
American Airlines Logo
12:20 am - 6:44 pm
MDE
-
MYR
17h 24m2 stops
$554American Airlines
Sun, Mar 1 - Fri, Mar 20
Spirit Airlines Logo
6:00 am - 1:28 am
MYR
-
MDE
19h 28m3 stops
Spirit Airlines Logo
3:15 pm - 2:42 pm
MDE
-
MYR
23h 27m3 stops
$568Spirit Airlines
Fri, Jan 2 - Sat, Jan 17
Spirit Airlines Logo
9:54 am - 10:55 am
MYR
-
MDE
25h 01m2 stops
Spirit Airlines Logo
2:54 pm - 6:08 pm
MDE
-
MYR
27h 14m2 stops
$578Spirit Airlines
Tue, Dec 30 - Tue, Jan 6

Spirit Airlines flights from Myrtle Beach to Medellín

Our best Spirit Airlines deals on Myrtle Beach to Medellín flight tickets
Spirit Airlines
Jan 2
MYR9:54 amMyrtle Beach Intl
15h 34m
1 stop
MDE1:28 amMedellín Jose Maria Cordova Intl
Jan 17
MDE3:15 pmMedellín Jose Maria Cordova Intl
28h 05m
1 stop
MYR7:20 pmMyrtle Beach Intl
$388
Find similar
Spirit Airlines
Jan 2
MYR9:54 amMyrtle Beach Intl
15h 34m
1 stop
MDE1:28 amMedellín Jose Maria Cordova Intl
Jan 17
MDE2:50 pmMedellín Jose Maria Cordova Intl
28h 30m
3 stops
MYR7:20 pmMyrtle Beach Intl
$513
Find similar
Spirit Airlines
Jan 2
MYR6:00 amMyrtle Beach Intl
19h 28m
3 stops
MDE1:28 amMedellín Jose Maria Cordova Intl
Jan 17
MDE3:15 pmMedellín Jose Maria Cordova Intl
20h 57m
2 stops
MYR12:12 pmMyrtle Beach Intl
$527
Find similar

American Airlines flights from Myrtle Beach to Medellín

Our best American Airlines deals on Myrtle Beach to Medellín flight tickets
American Airlines
Mar 1
MYR9:04 amMyrtle Beach Intl
12h 06m
2 stops
MDE9:10 pmMedellín Jose Maria Cordova Intl
Mar 21
MDE2:15 pmMedellín Jose Maria Cordova Intl
18h 46m
2 stops
MYR10:01 amMyrtle Beach Intl
$532
Find similar
American Airlines
Mar 1
MYR7:56 pmMyrtle Beach Intl
18h 10m
2 stops
MDE2:06 pmMedellín Jose Maria Cordova Intl
Mar 20
MDE12:20 amMedellín Jose Maria Cordova Intl
17h 24m
2 stops
MYR6:44 pmMyrtle Beach Intl
$554
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Fri 1/2

9:54 am-1:28 am

1 stop15h 34m

Medellín Jose Maria Cordova Intl

Sat 1/17

3:15 pm-7:20 pm

1 stop28h 05m

$388

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Fri 1/2

9:54 am-1:28 am

1 stop15h 34m

Medellín Jose Maria Cordova Intl

Sat 1/17

8:37 am-7:20 pm

2 stops10h 43m

$456

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Fri 1/2

9:54 am-1:28 am

1 stop15h 34m

Medellín Jose Maria Cordova Intl

Sat 1/17

2:50 pm-7:20 pm

3 stops28h 30m

$513

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Fri 1/2

6:00 am-1:28 am

3 stops19h 28m

Medellín Jose Maria Cordova Intl

Sat 1/17

3:15 pm-12:12 pm

2 stops20h 57m

$527

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Sun 3/1

9:04 am-9:10 pm

2 stops12h 06m

Medellín Jose Maria Cordova Intl

Sat 3/21

2:15 pm-10:01 am

2 stops18h 46m

$532

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Tue 12/30

9:54 am-1:28 am

1 stop15h 34m

Medellín Jose Maria Cordova Intl

Mon 1/5

2:25 am-6:08 pm

1 stop15h 43m

$547

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Tue 12/30

9:54 am-1:28 am

1 stop15h 34m

Medellín Jose Maria Cordova Intl

Tue 1/6

2:54 pm-6:08 pm

2 stops27h 14m

$550

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Sun 3/1

7:56 pm-2:06 pm

2 stops18h 10m

Medellín Jose Maria Cordova Intl

Fri 3/20

12:20 am-6:44 pm

2 stops17h 24m

$554

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Fri 1/2

6:00 am-1:28 am

3 stops19h 28m

Medellín Jose Maria Cordova Intl

Sat 1/17

3:15 pm-2:42 pm

3 stops23h 27m

$568

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Tue 12/30

9:54 am-10:55 am

2 stops25h 01m

Medellín Jose Maria Cordova Intl

Tue 1/6

2:54 pm-6:08 pm

2 stops27h 14m

$578

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from Myrtle Beach to Medellín

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Medellín?

The cheapest day to depart from Myrtle Beach to Medellín is on a Monday. Travelers who choose to depart for Medellín on a Monday will often find tickets for as low as $213. Flights from Myrtle Beach to Medellín on a Thursday will generally be more expensive and average around $936. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Cheap Myrtle Beach to Medellín flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Medellín

Fastest flight time

15h 34m

Direct flights

None
The fastest flight from Myrtle Beach to Medellín takes 15h 34m
There are no direct flights from Myrtle Beach to Medellín. There are no popular flight routes from Myrtle Beach to Medellín.
Search flight deals

  • How far is Myrtle Beach Intl to Medellín by plane?

    The distance between Myrtle Beach Intl and Medellín is about 1909.0 mi. Flights usually cover this in 15h 34m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Medellín?

    Prices for flights from Myrtle Beach Intl Airport to Medellín are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Medellín?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Medellín?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Medellín.

  • What documentation or ID do you need to fly to Medellín?

    The travel and health documents you'll need for your trip to Medellín may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Myrtle Beach to Medellín

Compare and see reviews for airlines that fly from Myrtle Beach to Medellín with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,190 reviews
Search Spirit Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Myrtle Beach to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Myrtle Beach to Medellín with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to Medellín flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Medellín right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Medellín, momondo offers a useful price alert feature which will track prices for flights to Medellín from Myrtle Beach and alert you when they change.

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Find better results for your trip to Colombia

Fly into one of these airports located in Medellín

Airports listed have a maximum distance of 10.8 mi from Medellín
Medellín Enrique Olaya Airport
Medellín Jose Maria Cordova Intl Airport