What airlines fly to South Carolina?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to South Carolina from Moline according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 3 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Moline Quad-City to South Carolina?

United Airlines is the most popular carrier operating from Moline Quad-City to South Carolina

When did momondo last update prices for flights from Moline Quad-City Airport to South Carolina?

Prices for flights from Moline Quad-City Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Moline Quad-City Airport to South Carolina?

There are 3 operators available for flights from Moline Quad-City Airport to South Carolina as of October 2026.

How old do you have to be to fly from Moline Quad-City Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Moline Quad-City Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$291 Cheap Flights from Moline to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Moline to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:55 am - 11:26 amMLI Moline Quad-City-CHS Charleston

4h 31m1 stop Atlanta Hartsfield-Jackson

6:30 am - 10:26 amCHS Charleston-MLI Moline Quad-City

4h 56m1 stop Atlanta Hartsfield-Jackson

$291Delta

Sat, Apr 3 - Wed, Apr 7

8:27 am - 1:49 pmMLI Moline Quad-City-CHS Charleston

4h 22m1 stop Chicago O'Hare Intl

4:55 pm - 9:10 pmCHS Charleston-MLI Moline Quad-City

5h 15m1 stop Chicago O'Hare Intl

$315United Airlines

Fri, Feb 26 - Tue, Mar 2

6:03 pm - 12:21 amMLI Moline Quad-City-CHS Charleston

5h 18m1 stop Chicago O'Hare Intl

3:28 pm - 12:10 amCHS Charleston-MLI Moline Quad-City

9h 42m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$320American Airlines

Fri, Feb 26 - Tue, Mar 2

6:30 am - 5:22 pmMLI Moline Quad-City-CHS Charleston

9h 52m2 stops Chicago O'Hare Intl Newark

11:07 am - 9:10 pmCHS Charleston-MLI Moline Quad-City

11h 03m2 stops Newark Chicago O'Hare Intl

$326United Airlines

Fri, Feb 26 - Tue, Mar 2

6:03 pm - 12:21 amMLI Moline Quad-City-CHS Charleston

5h 18m1 stop Chicago O'Hare Intl

6:18 am - 10:51 amCHS Charleston-MLI Moline Quad-City

5h 33m1 stop Chicago O'Hare Intl

$339American Airlines

Thu, Apr 1 - Mon, Apr 5

6:10 am - 11:08 amMLI Moline Quad-City-CAE Columbia Metropolitan

3h 58m1 stop Atlanta Hartsfield-Jackson

6:02 pm - 11:01 pmCAE Columbia Metropolitan-MLI Moline Quad-City

5h 59m1 stop Atlanta Hartsfield-Jackson

$339Delta

Tue, Dec 8 - Thu, Dec 17

11:08 am - 5:14 pmMLI Moline Quad-City-CAE Columbia Metropolitan

5h 06m1 stop Atlanta Hartsfield-Jackson

6:02 pm - 11:01 pmCAE Columbia Metropolitan-MLI Moline Quad-City

5h 59m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sun, Dec 6 - Thu, Dec 17

5:00 am - 11:21 amMLI Moline Quad-City-CHS Charleston

5h 21m1 stop Chicago O'Hare Intl

3:29 pm - 9:22 pmCHS Charleston-MLI Moline Quad-City

6h 53m1 stop Chicago O'Hare Intl

$339United Airlines

Thu, Nov 19 - Mon, Nov 23

10:49 am - 8:48 amMLI Moline Quad-City-CHS Charleston

20h 59m1 stop Orlando Sanford Intl

9:38 pm - 8:17 amCHS Charleston-MLI Moline Quad-City

35h 39m2 stops Hartford Bradley Intl Orlando

$586Multiple Airlines

Sun, Nov 15 - Fri, Nov 20

9:06 am - 1:50 pmMLI Moline Quad-City-CHS Charleston

27h 44m1 stop Tampa St. Petersburg

3:00 pm - 1:51 pmCHS Charleston-MLI Moline Quad-City

47h 51m2 stops Cincinnati Cinci./N. Kentucky Tampa St. Petersburg

$642Multiple Airlines

Sun, Nov 29 - Thu, Dec 3

Cheap last minute flights

Enter your travel dates to find the best prices.

6:44 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

6h 22m1 stop Charlotte Douglas

11:58 am - 3:45 pmCAE Columbia Metropolitan-MLI Moline Quad-City

4h 47m1 stop Charlotte Douglas

$429American Airlines

Thu, Nov 5 - Tue, Nov 10

6:00 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

7h 06m2 stops Chicago O'Hare Intl Charlotte Douglas

6:01 am - 10:50 amCAE Columbia Metropolitan-MLI Moline Quad-City

5h 49m1 stop Chicago O'Hare Intl

$434American Airlines

Thu, Nov 5 - Tue, Nov 10

6:00 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

7h 06m2 stops Chicago O'Hare Intl Charlotte Douglas

8:17 am - 4:28 pmCAE Columbia Metropolitan-MLI Moline Quad-City

9h 11m2 stops Charlotte Douglas Chicago O'Hare Intl

$439American Airlines

Thu, Nov 5 - Tue, Nov 10

6:44 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

6h 22m1 stop Charlotte Douglas

11:58 am - 3:45 pmCAE Columbia Metropolitan-MLI Moline Quad-City

4h 47m1 stop Charlotte Douglas

$454American Airlines

Thu, Nov 5 - Tue, Nov 10

6:00 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

7h 06m2 stops Chicago O'Hare Intl Charlotte Douglas

6:01 am - 10:50 amCAE Columbia Metropolitan-MLI Moline Quad-City

5h 49m1 stop Chicago O'Hare Intl

$459American Airlines

Thu, Nov 5 - Tue, Nov 10

6:00 am - 2:06 pmMLI Moline Quad-City-CAE Columbia Metropolitan

7h 06m2 stops Chicago O'Hare Intl Charlotte Douglas

8:17 am - 4:28 pmCAE Columbia Metropolitan-MLI Moline Quad-City

9h 11m2 stops Charlotte Douglas Chicago O'Hare Intl

$465American Airlines

Thu, Nov 5 - Tue, Nov 10

5:00 am - 2:17 pmMLI Moline Quad-City-CAE Columbia Metropolitan

8h 17m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

5:37 pm - 10:59 pmCAE Columbia Metropolitan-MLI Moline Quad-City

6h 22m1 stop Chicago O'Hare Intl

$477United Airlines

Thu, Nov 5 - Mon, Nov 9

5:00 am - 2:17 pmMLI Moline Quad-City-CAE Columbia Metropolitan

8h 17m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

5:37 pm - 10:59 pmCAE Columbia Metropolitan-MLI Moline Quad-City

6h 22m1 stop Chicago O'Hare Intl

$477United Airlines

Thu, Nov 5 - Tue, Nov 10

5:00 am - 2:17 pmMLI Moline Quad-City-CAE Columbia Metropolitan

8h 17m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

12:22 pm - 9:22 pmCAE Columbia Metropolitan-MLI Moline Quad-City

10h 00m2 stops Newark Chicago O'Hare Intl

$482United Airlines

Thu, Nov 5 - Tue, Nov 10

5:00 am - 2:17 pmMLI Moline Quad-City-CAE Columbia Metropolitan

8h 17m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:52 pm - 10:59 pmCAE Columbia Metropolitan-MLI Moline Quad-City

9h 07m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$520United Airlines

Thu, Nov 5 - Mon, Nov 9

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Delta flights from Moline to South Carolina

Our best Delta deals on Moline to South Carolina flight tickets

Delta

Apr 3

MLI5:55 amMoline Quad-City

4h 31m

1 stop

CHS11:26 amCharleston

Apr 7

CHS6:30 amCharleston

4h 56m

1 stop

MLI10:26 amMoline Quad-City

$291

Delta

Jan 31

MLI6:10 amMoline Quad-City

4h 20m

1 stop

CAE11:30 amColumbia Metropolitan

Feb 8

CAE7:15 pmColumbia Metropolitan

4h 34m

1 stop

MLI10:49 pmMoline Quad-City

$339

Delta

Mar 21

MLI5:55 amMoline Quad-City

6h 52m

1 stop

CHS1:47 pmCharleston

Mar 27

CHS5:30 amCharleston

5h 56m

1 stop

MLI10:26 amMoline Quad-City

$350

United Airlines flights from Moline to South Carolina

Our best United Airlines deals on Moline to South Carolina flight tickets

United Airlines

Feb 26

MLI8:27 amMoline Quad-City

4h 22m

1 stop

CHS1:49 pmCharleston

Mar 2

CHS4:55 pmCharleston

5h 15m

1 stop

MLI9:10 pmMoline Quad-City

$315

United Airlines

Feb 26

MLI6:30 amMoline Quad-City

9h 52m

2 stops

CHS5:22 pmCharleston

Mar 2

CHS11:07 amCharleston

11h 03m

2 stops

MLI9:10 pmMoline Quad-City

$326

United Airlines

Nov 19

MLI6:30 amMoline Quad-City

6h 58m

2 stops

CHS2:28 pmCharleston

Nov 23

CHS7:00 pmCharleston

4h 59m

1 stop

MLI10:59 pmMoline Quad-City

$344

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sat 4/3

5:55 am-11:26 am

1 stop4h 31m

Charleston

Wed 4/7

6:30 am-10:26 am

1 stop4h 56m

$291

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Fri 2/26

8:27 am-1:49 pm

1 stop4h 22m

Charleston

Tue 3/2

4:55 pm-9:10 pm

1 stop5h 15m

$315

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Fri 2/26

6:03 pm-12:21 am

1 stop5h 18m

Charleston

Tue 3/2

3:28 pm-12:10 am

2 stops9h 42m

$320

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Fri 2/26

6:30 am-5:22 pm

2 stops9h 52m

Charleston

Tue 3/2

11:07 am-9:10 pm

2 stops11h 03m

$326

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 4/1

6:03 pm-12:21 am

1 stop5h 18m

Charleston

Mon 4/5

6:18 am-10:51 am

1 stop5h 33m

$339

MolineColumbia

MLI Moline Quad-City - CAE Columbia Metropolitan

MLICAE

Moline Quad-City

Tue 12/8

6:10 am-11:08 am

1 stop3h 58m

Columbia Metropolitan

Thu 12/17

6:02 pm-11:01 pm

1 stop5h 59m

$339

MolineColumbia

MLI Moline Quad-City - CAE Columbia Metropolitan

MLICAE

Moline Quad-City

Sun 12/6

11:08 am-5:14 pm

1 stop5h 06m

Columbia Metropolitan

Thu 12/17

6:02 pm-11:01 pm

1 stop5h 59m

$339

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 11/19

5:00 am-11:21 am

1 stop5h 21m

Charleston

Mon 11/23

3:29 pm-9:22 pm

1 stop6h 53m

$339

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sun 11/15

10:49 am-8:48 am

1 stop20h 59m

Charleston

Fri 11/20

9:38 pm-8:17 am

2 stops35h 39m

$586

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sun 11/29

9:06 am-1:50 pm

1 stop27h 44m

Charleston

Thu 12/3

3:00 pm-1:51 pm

2 stops47h 51m

$642

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first

How to get the cheapest flight ticket from Moline to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Moline is in September. Flight prices, which tend to average around $350, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Moline during May instead. Flights to South Carolina in May, while not as cheap as those in September, still average around $351.

Cheap Moline to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Moline to South Carolina

Best Price Found	$588
Fastest flight time	2h 20m
Direct flights	None

The best one-way flight to South Carolina from Moline in the past 72 hours is $588. The best round-trip flight deal from Moline to South Carolina found on momondo in the last 72 hours is $291.

The fastest flight from Moline to South Carolina takes 2h 20m

There are no direct flights from Moline to South Carolina. There are no popular flight routes from Moline to South Carolina.

Search flight deals

Frequently asked questions about flying from Moline to South Carolina

When did momondo last update prices for flights from Moline Quad-City Airport to South Carolina?
Prices for flights from Moline Quad-City Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Moline Quad-City Airport to South Carolina?
There are 3 operators available for flights from Moline Quad-City Airport to South Carolina as of October 2026.
How old do you have to be to fly from Moline Quad-City Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Moline Quad-City Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Moline to South Carolina

Compare and see reviews for airlines that fly from Moline to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $260	Free Cancellation	Rating 7.3 10,462 reviews	Search United Airlines flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.0 12,223 reviews	Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,697 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Moline to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Moline to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Moline to South Carolina with flexible booking policies on momondo?

All flight searches from Moline to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Moline to South Carolina?

Once all potential Moline to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Moline to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Moline to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.