What is the cheapest airline that flies from Moline Quad-City to South Carolina?

American Airlines, United Airlines, and Delta are the most popular carriers operating from Moline Quad-City to South Carolina

How many flights depart from Moline to South Carolina on average per week?

The number of flights available between Moline and South Carolina is 13 per week as of September 2026. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

What airlines fly to South Carolina?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to South Carolina from Moline according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 3 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Moline Quad-City Airport to South Carolina?

Prices for flights from Moline Quad-City Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Moline Quad-City Airport to South Carolina?

There are 3 operators available for flights from Moline Quad-City Airport to South Carolina as of September 2026.

How old do you have to be to fly from Moline Quad-City Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Moline Quad-City Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$246 Cheap Flights from Moline to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Moline to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:08 am - 7:09 pmMLI Moline Quad-City-CHS Charleston

7h 01m1 stop Atlanta Hartsfield-Jackson

7:05 am - 12:16 pmCHS Charleston-MLI Moline Quad-City

6h 11m1 stop Atlanta Hartsfield-Jackson

$271Delta

Tue, Oct 27 - Wed, Nov 4

11:08 am - 7:09 pmMLI Moline Quad-City-CHS Charleston

7h 01m1 stop Atlanta Hartsfield-Jackson

6:00 am - 12:16 pmCHS Charleston-MLI Moline Quad-City

7h 16m1 stop Atlanta Hartsfield-Jackson

$271Delta

Tue, Oct 27 - Tue, Nov 3

2:31 pm - 10:12 pmMLI Moline Quad-City-CHS Charleston

6h 41m1 stop Chicago O'Hare Intl

3:29 pm - 9:22 pmCHS Charleston-MLI Moline Quad-City

6h 53m1 stop Chicago O'Hare Intl

$271United Airlines

Tue, Oct 27 - Sat, Oct 31

6:00 am - 11:04 amMLI Moline Quad-City-CHS Charleston

4h 04m1 stop Atlanta Hartsfield-Jackson

7:05 am - 12:16 pmCHS Charleston-MLI Moline Quad-City

6h 11m1 stop Atlanta Hartsfield-Jackson

$271Delta

Sat, Oct 24 - Tue, Nov 3

6:00 am - 3:40 pmMLI Moline Quad-City-CHS Charleston

8h 40m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

6:01 am - 4:32 pmCHS Charleston-MLI Moline Quad-City

11h 31m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$281American Airlines

Tue, Oct 27 - Sat, Oct 31

4:20 pm - 11:57 pmMLI Moline Quad-City-CHS Charleston

6h 37m1 stop Charlotte Douglas

7:13 am - 10:50 amCHS Charleston-MLI Moline Quad-City

4h 37m1 stop Chicago O'Hare Intl

$295American Airlines

Thu, Nov 12 - Tue, Nov 17

6:30 am - 1:56 pmMLI Moline Quad-City-CHS Charleston

6h 26m1 stop Chicago O'Hare Intl

7:00 pm - 10:59 pmCHS Charleston-MLI Moline Quad-City

4h 59m1 stop Chicago O'Hare Intl

$295United Airlines

Tue, Oct 27 - Sun, Nov 1

6:30 am - 5:39 pmMLI Moline Quad-City-CHS Charleston

10h 09m2 stops Chicago O'Hare Intl Newark

7:00 pm - 10:59 pmCHS Charleston-MLI Moline Quad-City

4h 59m1 stop Chicago O'Hare Intl

$300United Airlines

Tue, Oct 27 - Sun, Nov 1

8:39 am - 8:48 amMLI Moline Quad-City-CHS Charleston

23h 09m1 stop Orlando Sanford Intl

3:42 pm - 8:49 amCHS Charleston-MLI Moline Quad-City

18h 07m1 stop Orlando

$328Multiple Airlines

Thu, Oct 29 - Sat, Oct 31

8:39 am - 8:48 amMLI Moline Quad-City-CHS Charleston

23h 09m1 stop Orlando Sanford Intl

3:42 pm - 8:49 amCHS Charleston-MLI Moline Quad-City

18h 07m1 stop Orlando

$328Multiple Airlines

Sun, Oct 25 - Sat, Oct 31

Cheap last minute flights

Enter your travel dates to find the best prices.

4:57 pm - 10:59 pmMLI Moline Quad-City-CHS Charleston

5h 02m1 stop Chicago O'Hare Intl

4:26 pm - 9:55 pmCHS Charleston-MLI Moline Quad-City

6h 29m1 stop Charlotte Douglas

$403American Airlines

Wed, Sep 16 - Sun, Sep 20

6:32 am - 1:58 pmMLI Moline Quad-City-CHS Charleston

6h 26m1 stop Chicago O'Hare Intl

5:45 am - 12:31 pmCHS Charleston-MLI Moline Quad-City

7h 46m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$408United Airlines

Wed, Sep 16 - Sun, Sep 20

11:19 am - 5:31 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

5h 12m1 stop Atlanta Hartsfield-Jackson

6:45 am - 10:13 amSAV Savannah/Hilton Head-MLI Moline Quad-City

4h 28m1 stop Atlanta Hartsfield-Jackson

$409Delta

Thu, Sep 17 - Sun, Sep 20

6:32 am - 2:38 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

7h 06m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:10 am - 10:07 amSAV Savannah/Hilton Head-MLI Moline Quad-City

4h 57m1 stop Chicago O'Hare Intl

$414United Airlines

Thu, Sep 17 - Sun, Sep 20

11:19 am - 7:04 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

6h 45m1 stop Atlanta Hartsfield-Jackson

6:36 pm - 10:30 pmSAV Savannah/Hilton Head-MLI Moline Quad-City

4h 54m1 stop Atlanta Hartsfield-Jackson

$421Delta

Wed, Sep 16 - Tue, Sep 22

5:16 pm - 11:55 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

5h 39m1 stop Atlanta Hartsfield-Jackson

6:45 am - 10:13 amSAV Savannah/Hilton Head-MLI Moline Quad-City

4h 28m1 stop Atlanta Hartsfield-Jackson

$421Delta

Sat, Sep 19 - Tue, Sep 22

6:00 am - 11:26 amMLI Moline Quad-City-SAV Savannah/Hilton Head

4h 26m1 stop Chicago O'Hare Intl

4:15 pm - 9:09 pmSAV Savannah/Hilton Head-MLI Moline Quad-City

5h 54m1 stop Charlotte Douglas

$444American Airlines

Thu, Sep 17 - Mon, Sep 21

6:32 am - 12:10 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

4h 38m1 stop Chicago O'Hare Intl

9:50 am - 7:31 pmSAV Savannah/Hilton Head-MLI Moline Quad-City

10h 41m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$449United Airlines

Thu, Sep 17 - Mon, Sep 21

8:03 am - 1:49 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

4h 46m1 stop Charlotte Douglas

3:18 pm - 12:05 amSAV Savannah/Hilton Head-MLI Moline Quad-City

9h 47m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$506American Airlines

Wed, Sep 16 - Tue, Sep 22

6:00 am - 4:42 pmMLI Moline Quad-City-SAV Savannah/Hilton Head

9h 42m2 stops Chicago O'Hare Intl Charlotte Douglas

11:56 am - 4:27 pmSAV Savannah/Hilton Head-MLI Moline Quad-City

5h 31m1 stop Chicago O'Hare Intl

$506American Airlines

Tue, Sep 15 - Wed, Sep 23

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American Airlines flights from Moline to South Carolina

Our best American Airlines deals on Moline to South Carolina flight tickets

American Airlines

Oct 27

MLI6:00 amMoline Quad-City

8h 40m

2 stops

CHS3:40 pmCharleston

Oct 31

CHS6:01 amCharleston

11h 31m

2 stops

MLI4:32 pmMoline Quad-City

$281

American Airlines

Oct 27

MLI6:00 amMoline Quad-City

8h 40m

2 stops

CHS3:40 pmCharleston

Nov 1

CHS5:05 amCharleston

6h 45m

2 stops

MLI10:50 amMoline Quad-City

$305

American Airlines

Dec 5

MLI11:20 amMoline Quad-City

8h 41m

2 stops

SAV9:01 pmSavannah/Hilton Head

Dec 10

SAV11:04 amSavannah/Hilton Head

5h 51m

1 stop

MLI3:55 pmMoline Quad-City

$315

Delta flights from Moline to South Carolina

Our best Delta deals on Moline to South Carolina flight tickets

Delta

Oct 27

MLI11:08 amMoline Quad-City

7h 01m

1 stop

CHS7:09 pmCharleston

Nov 4

CHS7:05 amCharleston

6h 11m

1 stop

MLI12:16 pmMoline Quad-City

$271

Delta

Oct 24

MLI6:00 amMoline Quad-City

4h 04m

1 stop

CHS11:04 amCharleston

Oct 30

CHS4:20 pmCharleston

7h 10m

1 stop

MLI10:30 pmMoline Quad-City

$295

Delta

Oct 23

MLI5:04 pmMoline Quad-City

5h 53m

1 stop

SAV11:57 pmSavannah/Hilton Head

Oct 27

SAV6:31 pmSavannah/Hilton Head

4h 59m

1 stop

MLI10:30 pmMoline Quad-City

$310

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

11:08 am-7:09 pm

1 stop7h 01m

Charleston

Wed 11/4

7:05 am-12:16 pm

1 stop6h 11m

$271

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

11:08 am-7:09 pm

1 stop7h 01m

Charleston

Tue 11/3

6:00 am-12:16 pm

1 stop7h 16m

$271

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

2:31 pm-10:12 pm

1 stop6h 41m

Charleston

Sat 10/31

3:29 pm-9:22 pm

1 stop6h 53m

$271

Quickest round-trip

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sat 10/24

6:00 am-11:04 am

1 stop4h 04m

Charleston

Tue 11/3

7:05 am-12:16 pm

1 stop6h 11m

$271

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

6:00 am-3:40 pm

2 stops8h 40m

Charleston

Sat 10/31

6:01 am-4:32 pm

2 stops11h 31m

$281

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 11/12

4:20 pm-11:57 pm

1 stop6h 37m

Charleston

Tue 11/17

7:13 am-10:50 am

1 stop4h 37m

$295

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

6:30 am-1:56 pm

1 stop6h 26m

Charleston

Sun 11/1

7:00 pm-10:59 pm

1 stop4h 59m

$295

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Tue 10/27

6:30 am-5:39 pm

2 stops10h 09m

Charleston

Sun 11/1

7:00 pm-10:59 pm

1 stop4h 59m

$300

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 10/29

8:39 am-8:48 am

1 stop23h 09m

Charleston

Sat 10/31

3:42 pm-8:49 am

1 stop18h 07m

$328

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sun 10/25

8:39 am-8:48 am

1 stop23h 09m

Charleston

Sat 10/31

3:42 pm-8:49 am

1 stop18h 07m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Moline to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Moline is in September. Flight prices, which tend to average around $318, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Moline during October instead. Flights to South Carolina in October, while not as cheap as those in September, still average around $351.

Cheap Moline to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Moline to South Carolina

Best Price Found	$246
Fastest flight time	2h 19m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Moline in the past 72 hours is $246. The best round-trip flight deal from Moline to South Carolina found on momondo in the last 72 hours is $271.

The fastest flight from Moline to South Carolina takes 2h 19m

Direct flights go from Moline to South Carolina every day.

There are 57 airports in South Carolina. From Moline there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Moline to South Carolina

When did momondo last update prices for flights from Moline Quad-City Airport to South Carolina?
Prices for flights from Moline Quad-City Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Moline Quad-City Airport to South Carolina?
There are 3 operators available for flights from Moline Quad-City Airport to South Carolina as of September 2026.
How old do you have to be to fly from Moline Quad-City Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Moline Quad-City Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Moline to South Carolina

Compare and see reviews for airlines that fly from Moline to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $260	Free Cancellation	Rating 7.4 10,213 reviews	Search United Airlines flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.1 12,053 reviews	Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,564 reviews	Search Delta flights

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Why should I use momondo to find a flight deal from Moline to South Carolina?

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Can I find flights from Moline to South Carolina with flexible booking policies on momondo?

All flight searches from Moline to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

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Of course. momondo tracks the price of Moline to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.