Cheap flights from Missouri to District of Columbia from $52

In general, January is the cheapest month to fly from Missouri to District of Columbia. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $351. If you don’t want to visit District of Columbia in January, then you should wait until December to fly from Missouri, when ticket prices are also cheap, with an average price of $354.

The cheapest day to depart on your flight to District of Columbia is on a Friday when prices can be found for as low as $411. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $530.

Flying to District of Columbia from Missouri in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $376 when looking at flights departing in the afternoon. Flights to District of Columbia are more costly at noon, with an average ticket price of $554. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Lambert-St Louis to Washington, D.C. Reagan-National for the best Missouri - District of Columbia flight prices

There are 4 cabin classes available to choose from on Missouri to District of Columbia flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 16% on your flight if you consider stops on a Missouri to District of Columbia flight.

Southwest, United Airlines, and Delta are the most popular carriers operating from Missouri to District of Columbia

Southwest, American Airlines and United Airlines are the top three most popular airlines that fly to District of Columbia from Missouri according to our data. Southwest is the first choice among our users, with 47% of people opting to fly with this airline when traveling to District of Columbia. Keep in mind that there are 6 different airlines that fly to District of Columbia on a routine basis, so you have a few additional options to choose from.

As of September 2026, there are 18 flights per day flying from Missouri to District of Columbia. The most common time of day flights depart is 11:00AM, with 53% of flights taking off at noon.

As of September 2026, there are 129 flights per week flying from Missouri to District of Columbia. The most common day of the week flights depart is Wed, with 22% of flights taking off on this day.