What airlines fly to South Carolina?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to South Carolina from Milwaukee according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Milwaukee to South Carolina on average per week?

The number of flights available between Milwaukee and South Carolina is 15 per week as of July 2026. The most frequent departure day is Thu, with 20% of weekly flights leaving on this day.

What is the cheapest airline that flies from Milwaukee-Mitchell to South Carolina?

American Airlines, Delta, and Southwest are the most popular carriers operating from Milwaukee-Mitchell to South Carolina

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to South Carolina?

Prices for flights from Milwaukee-Mitchell Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Milwaukee-Mitchell Airport to South Carolina?

As of July 2026, there are 4 operators available to choose from for flights from Milwaukee-Mitchell Airport to South Carolina.

How old do you have to be to fly from Milwaukee-Mitchell Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$112 Cheap Flights from Milwaukee to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Milwaukee to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:43 am - 4:50 pm

MKE

CLT

8h 07m

1 stop

6:25 pm - 7:33 pm

CLT

MKE

2h 08mnonstop

$237American Airlines

Sat, Sep 12 - Sat, Sep 12

2:49 pm - 9:10 pm

MKE

MYR

5h 21m

1 stop

6:04 pm - 11:59 pm

MYR

MKE

6h 55m

1 stop

$243American Airlines

Sat, Aug 8 - Tue, Aug 11

1:30 pm - 6:10 pm

MKE

CHS

3h 40m

1 stop

8:10 am - 7:55 pm

CHS

MKE

12h 45m

2 stops

$254Southwest

Sat, Aug 15 - Wed, Aug 19

5:00 am - 9:55 am

MKE

GSP

3h 55m

1 stop

10:25 am - 6:55 pm

GSP

MKE

9h 30m

2 stops

$258United Airlines

Wed, Aug 5 - Wed, Aug 12

8:43 am - 4:38 pm

MKE

CLT

6h 55m

1 stop

9:43 pm - 7:58 am

CLT

MKE

11h 15m

1 stop

$258Frontier

Tue, Aug 11 - Wed, Aug 12

4:29 pm - 11:59 pm

MKE

CHS

6h 30m

1 stop

7:10 am - 12:35 pm

CHS

MKE

6h 25m

1 stop

$259Delta

Thu, Oct 22 - Tue, Oct 27

8:10 pm - 9:05 pm

MKE

CLT

23h 55m

1 stop

8:11 pm - 7:15 pm

CLT

MKE

24h 04m

1 stop

$259Frontier

Thu, Oct 8 - Sun, Oct 11

7:18 am - 1:58 pm

MKE

CHS

5h 40m

1 stop

6:30 am - 12:38 pm

CHS

MKE

7h 08m

1 stop

$261United Airlines

Tue, Sep 1 - Thu, Sep 3

7:40 am - 12:45 pm

MKE

CLT

4h 05m

1 stop

7:55 am - 3:45 pm

CLT

MKE

8h 50m

2 stops

$264Southwest

Tue, Aug 18 - Sat, Aug 22

10:22 am - 3:53 pm

MKE

SAV

4h 31m

1 stop

10:23 am - 4:14 pm

SAV

MKE

6h 51m

1 stop

$267Delta

Tue, Aug 18 - Sat, Aug 22

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Frontier flights from Milwaukee to South Carolina

Our best Frontier deals on Milwaukee to South Carolina flight tickets

Frontier

Oct 8

MKE8:10 pmMilwaukee-Mitchell

23h 55m

1 stop

CLT9:05 pmCharlotte Douglas

Oct 11

CLT8:11 pmCharlotte Douglas

24h 04m

1 stop

MKE7:15 pmMilwaukee-Mitchell

$259

Frontier

Jul 30

MKE8:43 amMilwaukee-Mitchell

7h 15m

1 stop

CLT4:58 pmCharlotte Douglas

Aug 15

CLT9:43 pmCharlotte Douglas

11h 15m

1 stop

MKE7:58 amMilwaukee-Mitchell

$263

Frontier

Aug 18

MKE12:10 pmMilwaukee-Mitchell

18h 51m

1 stop

CLT8:01 amCharlotte Douglas

Aug 22

CLT9:52 pmCharlotte Douglas

14h 21m

1 stop

MKE11:13 amMilwaukee-Mitchell

$268

Southwest flights from Milwaukee to South Carolina

Our best Southwest deals on Milwaukee to South Carolina flight tickets

Southwest

Aug 22

MKE5:45 amMilwaukee-Mitchell

4h 20m

1 stop

MYR11:05 amMyrtle Beach Intl

Aug 28

MYR6:40 amMyrtle Beach Intl

10h 40m

2 stops

MKE4:20 pmMilwaukee-Mitchell

$248

Southwest

Aug 15

MKE1:30 pmMilwaukee-Mitchell

3h 40m

1 stop

CHS6:10 pmCharleston

Aug 19

CHS8:10 amCharleston

12h 45m

2 stops

MKE7:55 pmMilwaukee-Mitchell

$254

Southwest

Aug 18

MKE3:10 pmMilwaukee-Mitchell

5h 00m

1 stop

CLT9:10 pmCharlotte Douglas

Aug 22

CLT7:55 amCharlotte Douglas

4h 10m

1 stop

MKE11:05 amMilwaukee-Mitchell

$258

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 9/12

7:43 am-4:50 pm

1 stop8h 07m

Charlotte Douglas

Sat 9/12

6:25 pm-7:33 pm

Nonstop2h 08m

$237

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

Sat 8/8

2:49 pm-9:10 pm

1 stop5h 21m

Myrtle Beach Intl

Tue 8/11

6:04 pm-11:59 pm

1 stop6h 55m

$243

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Sat 8/15

1:30 pm-6:10 pm

1 stop3h 40m

Charleston

Wed 8/19

8:10 am-7:55 pm

2 stops12h 45m

$254

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Wed 8/5

5:00 am-9:55 am

1 stop3h 55m

Greenville

Wed 8/12

10:25 am-6:55 pm

2 stops9h 30m

$258

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 8/11

8:43 am-4:38 pm

1 stop6h 55m

Charlotte Douglas

Wed 8/12

9:43 pm-7:58 am

1 stop11h 15m

$258

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Thu 10/22

4:29 pm-11:59 pm

1 stop6h 30m

Charleston

Tue 10/27

7:10 am-12:35 pm

1 stop6h 25m

$259

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 10/8

8:10 pm-9:05 pm

1 stop23h 55m

Charlotte Douglas

Sun 10/11

8:11 pm-7:15 pm

1 stop24h 04m

$259

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Tue 9/1

7:18 am-1:58 pm

1 stop5h 40m

Charleston

Thu 9/3

6:30 am-12:38 pm

1 stop7h 08m

$261

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 8/18

7:40 am-12:45 pm

1 stop4h 05m

Charlotte Douglas

Sat 8/22

7:55 am-3:45 pm

2 stops8h 50m

$264

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

Tue 8/18

10:22 am-3:53 pm

1 stop4h 31m

Savannah/Hilton Head

Sat 8/22

10:23 am-4:14 pm

1 stop6h 51m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Milwaukee to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Milwaukee is in March. Flight prices, which tend to average around $100, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to South Carolina from Milwaukee during September instead. Flights to South Carolina in September, while not as cheap as those in March, still average around $113.

How far in advance should I book a flight from Milwaukee to South Carolina?

You are more likely to see cheaper flights to South Carolina from Milwaukee when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $401 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Milwaukee for as low as $298 on momondo.

Cheap Milwaukee to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to South Carolina

Fastest flight time	2h 06m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Milwaukee to South Carolina takes 2h 06m

Direct flights go from Milwaukee to South Carolina every day.

There are 57 airports in South Carolina. From Milwaukee there are direct flights to Charlotte Douglas (CLT).

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Frequently asked questions about flying from Milwaukee to South Carolina

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to South Carolina?
Prices for flights from Milwaukee-Mitchell Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Milwaukee-Mitchell Airport to South Carolina?
As of July 2026, there are 4 operators available to choose from for flights from Milwaukee-Mitchell Airport to South Carolina.
How old do you have to be to fly from Milwaukee-Mitchell Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Milwaukee to South Carolina

Compare and see reviews for airlines that fly from Milwaukee to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $203	Free Cancellation	Rating 7.1 11,789 reviews	Search American Airlines flights
Delta	PriceFrom $209	Free Cancellation	Rating 7.8 8,453 reviews	Search Delta flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,955 reviews	Search United Airlines flights
Southwest	PriceFrom $290	Free Cancellation	Rating 7.9 4,248 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Milwaukee to South Carolina for you.

Can I find flights from Milwaukee to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Milwaukee to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.