How many flights depart from Milwaukee to South Carolina on average per week?

The number of flights available between Milwaukee and South Carolina is 6 per week as of April 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

What airlines fly to South Carolina?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to South Carolina from Milwaukee according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Milwaukee-Mitchell to South Carolina?

United Airlines, American Airlines, and Frontier are the most popular carriers operating from Milwaukee-Mitchell to South Carolina

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to South Carolina?

Prices for flights from Milwaukee-Mitchell Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Milwaukee-Mitchell Airport to South Carolina?

As of April 2026, there are 5 operators available to choose from for flights from Milwaukee-Mitchell Airport to South Carolina.

How old do you have to be to fly from Milwaukee-Mitchell Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$76 Cheap Flights from Milwaukee to South Carolina in 2026

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Find the cheapest flights from Milwaukee to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:33 am - 6:24 pm

MKE

CLT

7h 51m

1 stop

8:09 pm - 8:01 am

CLT

MKE

12h 52m

1 stop

$201Frontier

Sun, Apr 26 - Mon, May 4

8:09 am - 8:04 pm

MKE

CLT

10h 55m

1 stop

10:49 pm - 11:58 pm

CLT

MKE

2h 09mnonstop

$238American Airlines

Sat, Jul 18 - Sat, Jul 18

12:21 pm - 9:33 am

MKE

CHS

20h 12m

1 stop

4:34 pm - 8:01 am

CHS

MKE

16h 27m

1 stop

$242Multiple Airlines

Mon, May 4 - Wed, May 13

7:34 pm - 4:35 pm

MKE

CLT

20h 01m

1 stop

3:31 pm - 11:26 am

CLT

MKE

20h 55m

1 stop

$243Multiple Airlines

Fri, Apr 17 - Sun, Apr 19

10:22 am - 3:33 pm

MKE

HHH

4h 11m

1 stop

4:16 pm - 10:28 pm

HHH

MKE

7h 12m

1 stop

$276Delta

Sat, May 9 - Fri, May 15

5:23 am - 11:11 am

MKE

CAE

4h 48m

1 stop

5:38 am - 11:38 am

CAE

MKE

7h 00m

1 stop

$283Delta

Tue, May 12 - Sat, May 16

4:30 pm - 9:40 pm

MKE

GSP

4h 10m

1 stop

8:20 am - 11:55 am

GSP

MKE

4h 35m

1 stop

$319Southwest

Wed, Apr 29 - Wed, May 6

7:35 am - 12:10 pm

MKE

GSP

3h 35m

1 stop

5:05 pm - 10:15 pm

GSP

MKE

6h 10m

2 stops

$324Southwest

Wed, Apr 29 - Wed, May 6

6:05 am - 1:46 pm

MKE

CAE

6h 41m

1 stop

2:29 pm - 5:53 pm

CAE

MKE

4h 24m

1 stop

$341United Airlines

Wed, May 27 - Wed, Jun 3

3:25 pm - 11:59 pm

MKE

CAE

7h 34m

2 stops

2:37 pm - 8:48 pm

CAE

MKE

7h 11m

2 stops

$345United Airlines

Sat, May 2 - Sat, May 9

Frontier flights from Milwaukee to South Carolina

Our best Frontier deals on Milwaukee to South Carolina flight tickets

Frontier

Apr 26

MKE9:33 amMilwaukee-Mitchell

7h 51m

1 stop

CLT6:24 pmCharlotte Douglas

May 4

CLT8:09 pmCharlotte Douglas

12h 52m

1 stop

MKE8:01 amMilwaukee-Mitchell

$201

Frontier

Apr 9

MKE7:02 pmMilwaukee-Mitchell

13h 35m

1 stop

CLT9:37 amCharlotte Douglas

Apr 11

CLT10:08 amCharlotte Douglas

6h 12m

1 stop

MKE3:20 pmMilwaukee-Mitchell

$233

Frontier

Apr 27

MKE5:05 pmMilwaukee-Mitchell

22h 30m

2 stops

CLT4:35 pmCharlotte Douglas

May 2

CLT8:09 pmCharlotte Douglas

13h 29m

1 stop

MKE8:38 amMilwaukee-Mitchell

$260

Southwest flights from Milwaukee to South Carolina

Our best Southwest deals on Milwaukee to South Carolina flight tickets

Southwest

Apr 29

MKE4:30 pmMilwaukee-Mitchell

4h 10m

1 stop

GSP9:40 pmGreenville

May 6

GSP8:20 amGreenville

4h 35m

1 stop

MKE11:55 amMilwaukee-Mitchell

$319

Southwest

Apr 29

MKE7:35 amMilwaukee-Mitchell

3h 35m

1 stop

GSP12:10 pmGreenville

May 6

GSP5:05 pmGreenville

6h 10m

2 stops

MKE10:15 pmMilwaukee-Mitchell

$324

Southwest

Apr 29

MKE8:00 amMilwaukee-Mitchell

7h 20m

2 stops

GSP4:20 pmGreenville

May 6

GSP12:50 pmGreenville

9h 20m

2 stops

MKE9:10 pmMilwaukee-Mitchell

$329

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sun 4/26

9:33 am-6:24 pm

1 stop7h 51m

Charlotte Douglas

Mon 5/4

8:09 pm-8:01 am

1 stop12h 52m

$201

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 7/18

8:09 am-8:04 pm

1 stop10h 55m

Charlotte Douglas

Sat 7/18

10:49 pm-11:58 pm

Nonstop2h 09m

$238

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Mon 5/4

12:21 pm-9:33 am

1 stop20h 12m

Charleston

Wed 5/13

4:34 pm-8:01 am

1 stop16h 27m

$242

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 4/17

7:34 pm-4:35 pm

1 stop20h 01m

Charlotte Douglas

Sun 4/19

3:31 pm-11:26 am

1 stop20h 55m

$243

MilwaukeeHilton Head Island

MKE - HHH

MKEHHH

Milwaukee-Mitchell

Sat 5/9

10:22 am-3:33 pm

1 stop4h 11m

Hilton Head Island

Fri 5/15

4:16 pm-10:28 pm

1 stop7h 12m

$276

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Tue 5/12

5:23 am-11:11 am

1 stop4h 48m

Columbia Metropolitan

Sat 5/16

5:38 am-11:38 am

1 stop7h 00m

$283

Quickest round-trip

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Wed 4/29

4:30 pm-9:40 pm

1 stop4h 10m

Greenville

Wed 5/6

8:20 am-11:55 am

1 stop4h 35m

$319

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Wed 4/29

7:35 am-12:10 pm

1 stop3h 35m

Greenville

Wed 5/6

5:05 pm-10:15 pm

2 stops6h 10m

$324

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 5/27

6:05 am-1:46 pm

1 stop6h 41m

Columbia Metropolitan

Wed 6/3

2:29 pm-5:53 pm

1 stop4h 24m

$341

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Sat 5/2

3:25 pm-11:59 pm

2 stops7h 34m

Columbia Metropolitan

Sat 5/9

2:37 pm-8:48 pm

2 stops7h 11m

$345

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Milwaukee to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Milwaukee is in January. Flight prices, which tend to average around $314, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Milwaukee during August instead. Flights to South Carolina in August, while not as cheap as those in January, still average around $346.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Milwaukee when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Milwaukee for as low as $314 on momondo.

Cheap Milwaukee to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to South Carolina

Fastest flight time	2h 10m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Milwaukee to South Carolina takes 2h 10m

Direct flights go from Milwaukee to South Carolina every day.

There are 57 airports in South Carolina. From Milwaukee there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Milwaukee to South Carolina

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to South Carolina?
Prices for flights from Milwaukee-Mitchell Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Milwaukee-Mitchell Airport to South Carolina?
As of April 2026, there are 5 operators available to choose from for flights from Milwaukee-Mitchell Airport to South Carolina.
How old do you have to be to fly from Milwaukee-Mitchell Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Milwaukee to South Carolina

Compare and see reviews for airlines that fly from Milwaukee to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $127	Free Cancellation	Rating 7.9 8,367 reviews	Search Delta flights
Spirit Airlines	PriceFrom $193	Free Cancellation	Rating 6.3 8,572 reviews	Search Spirit Airlines flights
Southwest	PriceFrom $201	Free Cancellation	Rating 8.0 4,334 reviews	Search Southwest flights
American Airlines	PriceFrom $203	Free Cancellation	Rating 7.1 11,545 reviews	Search American Airlines flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,529 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Milwaukee to South Carolina for you.

Can I find flights from Milwaukee to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Milwaukee to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.