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Cheap flights from Milwaukee to South Carolina from $70

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to South Carolina departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Milwaukee to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:52 pm - 8:13 am
MKE
-
CLT
11h 21m
1 stop
Frontier Logo
1:17 pm - 9:43 am
CLT
-
MKE
21h 26m
1 stop
$220Frontier
Mon, Feb 16 - Thu, Feb 19
Frontier Logo
7:52 pm - 8:13 am
MKE
-
CLT
11h 21m
1 stop
Frontier Logo
1:17 pm - 9:43 am
CLT
-
MKE
21h 26m
1 stop
$221Frontier
Mon, Feb 16 - Thu, Feb 19
Delta Logo
5:30 am - 11:08 am
MKE
-
CAE
4h 38m
1 stop
Delta Logo
5:40 am - 11:36 am
CAE
-
MKE
6h 56m
1 stop
$269Delta
Thu, May 21 - Sun, May 24
American Airlines Logo
3:05 pm - 11:50 pm
MKE
-
CAE
7h 45m
1 stop
American Airlines Logo
7:26 pm - 11:24 pm
CAE
-
MKE
4h 58m
1 stop
$279American Airlines
Thu, Feb 19 - Mon, Feb 23
American Airlines Logo
11:33 am - 4:44 pm
MKE
-
HHH
4h 11m
1 stop
American Airlines Logo
6:20 pm - 11:55 pm
HHH
-
MKE
6h 35m
1 stop
$279American Airlines
Tue, Feb 17 - Sat, Feb 21
Delta Logo
12:32 pm - 6:28 pm
MKE
-
CAE
4h 56m
1 stop
Delta Logo
5:38 am - 9:05 am
CAE
-
MKE
4h 27m
1 stop
$314Delta
Thu, Apr 16 - Sun, Apr 19
Southwest Logo
5:30 am - 3:20 pm
MKE
-
SAV
8h 50m
2 stops
Southwest Logo
8:10 am - 1:50 pm
SAV
-
MKE
6h 40m
1 stop
$322Southwest
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
2:32 pm - 8:47 pm
MKE
-
GSP
5h 15m
1 stop
United Airlines Logo
6:30 am - 11:32 am
GSP
-
MKE
6h 02m
1 stop
$325United Airlines
Mon, Apr 20 - Thu, Apr 23
United Airlines Logo
7:00 am - 2:47 pm
MKE
-
SAV
6h 47m
2 stops
United Airlines Logo
6:30 am - 3:20 pm
SAV
-
MKE
9h 50m
2 stops
$327United Airlines
Tue, Feb 24 - Sat, Feb 28
Southwest Logo
12:40 pm - 10:15 pm
MKE
-
GSP
8h 35m
2 stops
Southwest Logo
1:50 pm - 10:50 pm
GSP
-
MKE
10h 00m
2 stops
$356Southwest
Mon, Apr 20 - Thu, Apr 23

Southwest flights from Milwaukee to South Carolina

Our best Southwest deals on Milwaukee to South Carolina flight tickets
Southwest
Apr 4
MKE7:00 amMilwaukee-Mitchell
4h 20m
1 stop
CLT12:20 pmCharlotte Douglas
Apr 7
CLT5:35 pmCharlotte Douglas
5h 20m
1 stop
MKE9:55 pmMilwaukee-Mitchell
$323
Southwest
Apr 4
MKE5:50 amMilwaukee-Mitchell
8h 20m
2 stops
CLT3:10 pmCharlotte Douglas
Apr 7
CLT1:45 pmCharlotte Douglas
9h 00m
2 stops
MKE9:45 pmMilwaukee-Mitchell
$334
Southwest
May 20
MKE4:05 pmMilwaukee-Mitchell
3h 50m
1 stop
CLT8:55 pmCharlotte Douglas
May 29
CLT8:25 pmCharlotte Douglas
4h 00m
1 stop
MKE11:25 pmMilwaukee-Mitchell
$346

Frontier flights from Milwaukee to South Carolina

Our best Frontier deals on Milwaukee to South Carolina flight tickets
Frontier
Feb 16
MKE7:52 pmMilwaukee-Mitchell
11h 21m
1 stop
CLT8:13 amCharlotte Douglas
Feb 19
CLT1:17 pmCharlotte Douglas
21h 26m
1 stop
MKE9:43 amMilwaukee-Mitchell
$220
Frontier
Feb 16
MKE7:52 pmMilwaukee-Mitchell
11h 21m
1 stop
CLT8:13 amCharlotte Douglas
Feb 19
CLT1:17 pmCharlotte Douglas
21h 26m
1 stop
MKE9:43 amMilwaukee-Mitchell
$221
Frontier
Feb 26
MKE7:37 pmMilwaukee-Mitchell
11h 21m
1 stop
CLT7:58 amCharlotte Douglas
Feb 28
CLT9:28 amCharlotte Douglas
10h 24m
1 stop
MKE6:52 pmMilwaukee-Mitchell
$242

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 2/16

7:52 pm-8:13 am

1 stop11h 21m

Charlotte Douglas

Thu 2/19

1:17 pm-9:43 am

1 stop21h 26m

$220

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 2/16

7:52 pm-8:13 am

1 stop11h 21m

Charlotte Douglas

Thu 2/19

1:17 pm-9:43 am

1 stop21h 26m

$221

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Thu 5/21

5:30 am-11:08 am

1 stop4h 38m

Columbia Metropolitan

Sun 5/24

5:40 am-11:36 am

1 stop6h 56m

$269

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Thu 2/19

3:05 pm-11:50 pm

1 stop7h 45m

Columbia Metropolitan

Mon 2/23

7:26 pm-11:24 pm

1 stop4h 58m

$279

MilwaukeeHilton Head Island

MKE - HHH

MKEHHH

Milwaukee-Mitchell

Tue 2/17

11:33 am-4:44 pm

1 stop4h 11m

Hilton Head Island

Sat 2/21

6:20 pm-11:55 pm

1 stop6h 35m

$279

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Thu 4/16

12:32 pm-6:28 pm

1 stop4h 56m

Columbia Metropolitan

Sun 4/19

5:38 am-9:05 am

1 stop4h 27m

$314

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

Tue 2/24

5:30 am-3:20 pm

2 stops8h 50m

Savannah/Hilton Head

Sat 2/28

8:10 am-1:50 pm

1 stop6h 40m

$322

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Mon 4/20

2:32 pm-8:47 pm

1 stop5h 15m

Greenville

Thu 4/23

6:30 am-11:32 am

1 stop6h 02m

$325

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

Tue 2/24

7:00 am-2:47 pm

2 stops6h 47m

Savannah/Hilton Head

Sat 2/28

6:30 am-3:20 pm

2 stops9h 50m

$327

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Mon 4/20

12:40 pm-10:15 pm

2 stops8h 35m

Greenville

Thu 4/23

1:50 pm-10:50 pm

2 stops10h 00m

$356

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Milwaukee to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Milwaukee is in February. Flight prices, which tend to average around $341, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Milwaukee during August instead. Flights to South Carolina in August, while not as cheap as those in February, still average around $346.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Milwaukee when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $373 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Milwaukee for as low as $304 on momondo.

Cheap Milwaukee to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to South Carolina

Fastest flight time

2h 09m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in South Carolina

57 airports
The fastest flight from Milwaukee to South Carolina takes 2h 09m
Direct flights go from Milwaukee to South Carolina on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There are 57 airports in South Carolina. From Milwaukee there are direct flights to Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to South Carolina?

    Prices for flights from Milwaukee-Mitchell Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to South Carolina?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Milwaukee to South Carolina

Compare and see reviews for airlines that fly from Milwaukee to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $127Free CancellationRating
7.9
8,145 reviews
Search Delta flights
Spirit AirlinesPriceFrom $189Free CancellationRating
6.3
8,411 reviews
Search Spirit Airlines flights
SouthwestPriceFrom $201Free CancellationRating
8.0
4,274 reviews
Search Southwest flights
United AirlinesPriceFrom $213Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
American AirlinesPriceFrom $223Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Milwaukee to South Carolina for you.

Can I find flights from Milwaukee to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Milwaukee to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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