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Cheap flights from Michigan to South Carolina from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Michigan to South Carolina departing on 3/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Michigan to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
5:16 pm - 8:31 pm
ORD
-
CLT
2h 15mnonstop
Frontier Logo
9:26 pm - 10:53 pm
CLT
-
ORD
2h 27mnonstop
$81Frontier
Fri, May 1 - Mon, May 4
Frontier Logo
1:02 pm - 4:12 pm
ORD
-
CLT
2h 10mnonstop
Frontier Logo
9:26 pm - 10:53 pm
CLT
-
ORD
2h 27mnonstop
$82Frontier
Thu, Apr 9 - Fri, Apr 17
Spirit Airlines Logo
9:53 pm - 8:40 am
DTW
-
CHS
10h 47m
1 stop
Spirit Airlines Logo
3:35 pm - 4:25 pm
CHS
-
DTW
24h 50m
1 stop
$129Spirit Airlines
Tue, Apr 14 - Fri, Apr 17
Spirit Airlines Logo
1:45 pm - 8:40 am
DTW
-
CHS
18h 55m
1 stop
Spirit Airlines Logo
3:35 pm - 12:30 am
CHS
-
DTW
8h 55m
1 stop
$132Spirit Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
5:45 pm - 8:57 pm
ORD
-
CHS
2h 12mnonstop
United Airlines Logo
6:45 pm - 8:27 pm
CHS
-
ORD
2h 42mnonstop
$293United Airlines
Sat, Mar 7 - Sat, Mar 14
Delta Logo
12:53 pm - 5:31 pm
MDW
-
SAV
3h 38m
1 stop
Delta Logo
6:36 pm - 10:28 pm
SAV
-
MDW
4h 52m
1 stop
$297Delta
Tue, Apr 21 - Wed, Apr 29
American Airlines Logo
1:26 pm - 4:44 pm
ORD
-
CHS
2h 18mnonstop
American Airlines Logo
12:23 pm - 1:53 pm
CHS
-
ORD
2h 30mnonstop
$297American Airlines
Tue, Mar 10 - Tue, Mar 24
United Airlines Logo
8:45 am - 2:40 pm
ORD
-
SAV
4h 55m
1 stop
United Airlines Logo
7:18 pm - 11:43 pm
SAV
-
ORD
5h 25m
1 stop
$297United Airlines
Wed, Apr 22 - Tue, Apr 28
American Airlines Logo
8:31 am - 11:49 am
ORD
-
CHS
2h 18mnonstop
American Airlines Logo
7:15 am - 8:55 am
CHS
-
ORD
2h 40mnonstop
$299American Airlines
Wed, Apr 8 - Mon, Apr 13
Delta Logo
6:04 am - 5:11 pm
ORD
-
SAV
10h 07m
1 stop
Delta Logo
1:33 pm - 6:13 pm
SAV
-
ORD
5h 40m
1 stop
$300Delta
Mon, Apr 20 - Tue, Apr 28

Frontier flights from Michigan to South Carolina

Our best Frontier deals on Michigan to South Carolina flight tickets
Frontier
May 1
ORD5:16 pmChicago O'Hare Intl
2h 15m
CLT8:31 pmCharlotte Douglas
May 4
CLT9:26 pmCharlotte Douglas
2h 27m
ORD10:53 pmChicago O'Hare Intl
$81
Frontier
Apr 9
ORD1:02 pmChicago O'Hare Intl
2h 10m
CLT4:12 pmCharlotte Douglas
Apr 17
CLT9:26 pmCharlotte Douglas
2h 27m
ORD10:53 pmChicago O'Hare Intl
$82
Frontier
Apr 2
ORD1:02 pmChicago O'Hare Intl
2h 10m
CLT4:12 pmCharlotte Douglas
Apr 9
CLT8:24 pmCharlotte Douglas
2h 23m
ORD9:47 pmChicago O'Hare Intl
$85

Delta flights from Michigan to South Carolina

Our best Delta deals on Michigan to South Carolina flight tickets
Delta
Apr 14
DTW7:19 amDetroit Metropolitan Wayne County
1h 50m
CLT9:09 amCharlotte Douglas
Apr 21
CLT12:40 pmCharlotte Douglas
1h 53m
DTW2:33 pmDetroit Metropolitan Wayne County
$159
Delta
Feb 28
DTW2:15 pmDetroit Metropolitan Wayne County
1h 50m
CLT4:05 pmCharlotte Douglas
Mar 1
CLT6:00 amCharlotte Douglas
1h 52m
DTW7:52 amDetroit Metropolitan Wayne County
$189
Delta
Feb 23
DTW7:05 amDetroit Metropolitan Wayne County
2h 02m
CLT9:07 amCharlotte Douglas
Mar 1
CLT6:00 amCharlotte Douglas
1h 52m
DTW7:52 amDetroit Metropolitan Wayne County
$224

momondo Fare Finder

 
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 5/1

5:16 pm-8:31 pm

Nonstop2h 15m

Charlotte Douglas

Mon 5/4

9:26 pm-10:53 pm

Nonstop2h 27m

$81

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 4/9

1:02 pm-4:12 pm

Nonstop2h 10m

Charlotte Douglas

Fri 4/17

9:26 pm-10:53 pm

Nonstop2h 27m

$82

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Tue 4/14

9:53 pm-8:40 am

1 stop10h 47m

Charleston

Fri 4/17

3:35 pm-4:25 pm

1 stop24h 50m

$129

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Tue 4/28

1:45 pm-8:40 am

1 stop18h 55m

Charleston

Sat 5/2

3:35 pm-12:30 am

1 stop8h 55m

$132

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Sat 3/7

5:45 pm-8:57 pm

Nonstop2h 12m

Charleston

Sat 3/14

6:45 pm-8:27 pm

Nonstop2h 42m

$293

ChicagoSavannah

MDW - SAV

MDWSAV

Chicago Midway

Tue 4/21

12:53 pm-5:31 pm

1 stop3h 38m

Savannah/Hilton Head

Wed 4/29

6:36 pm-10:28 pm

1 stop4h 52m

$297

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Tue 3/10

1:26 pm-4:44 pm

Nonstop2h 18m

Charleston

Tue 3/24

12:23 pm-1:53 pm

Nonstop2h 30m

$297

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Wed 4/22

8:45 am-2:40 pm

1 stop4h 55m

Savannah/Hilton Head

Tue 4/28

7:18 pm-11:43 pm

1 stop5h 25m

$297

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Wed 4/8

8:31 am-11:49 am

Nonstop2h 18m

Charleston

Mon 4/13

7:15 am-8:55 am

Nonstop2h 40m

$299

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Mon 4/20

6:04 am-5:11 pm

1 stop10h 07m

Savannah/Hilton Head

Tue 4/28

1:33 pm-6:13 pm

1 stop5h 40m

$300

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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2

See travel insights to South Carolina from

How to get the cheapest flight ticket from Michigan to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Michigan is in September. Flight prices, which tend to average around $209, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Michigan during August instead. Flights to South Carolina in August, while not as cheap as those in September, still average around $234.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $299. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $339.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Michigan to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $299. Try not to purchase tickets in the afternoon because they tend to be around $370. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Michigan to South Carolina flight route?

Fly from Grand Rapids Gerald R. Ford Intl to Myrtle Beach Intl for the best Michigan - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Michigan when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $331 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Michigan for as low as $224 on momondo.

What cabin class options are available on Michigan to South Carolina flights?

There are 4 cabin classes available to choose from on Michigan to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Michigan to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Michigan to South Carolina.

Cheap Michigan to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Michigan to South Carolina

Best Price Found

$208

Fastest flight time

1h 39m

Direct flights

Every day

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Michigan in the past 72 hours is $208. The best round-trip flight deal from Michigan to South Carolina found on momondo in the last 72 hours is $339.
The fastest flight from Michigan to South Carolina takes 1h 39m
Direct flights go from Michigan to South Carolina every day.
There are 57 airports in South Carolina. From Michigan there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Michigan to South Carolina?

    Prices for flights from Michigan to South Carolina were last updated today.

  • How many operators does momondo search for flights from Michigan to South Carolina?

  • How old do you have to be to fly from Michigan to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Michigan to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Michigan to South Carolina?

Best airlines flying from Michigan to South Carolina

Compare and see reviews for airlines that fly from Michigan to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $64Free CancellationRating
6.3
8,431 reviews
Search Spirit Airlines flights
Allegiant AirPriceFrom $78Free CancellationRating
7.2
710 reviews
Search Allegiant Air flights
DeltaPriceFrom $125Free CancellationRating
7.9
8,174 reviews
Search Delta flights
United AirlinesPriceFrom $151Free CancellationRating
7.4
9,259 reviews
Search United Airlines flights
American AirlinesPriceFrom $197Free CancellationRating
7.2
11,255 reviews
Search American Airlines flights
SouthwestPriceFrom $207Free CancellationRating
8.0
4,281 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Michigan to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Michigan to South Carolina for you.

Can I find flights from Michigan to South Carolina with flexible booking policies on momondo?

Flights from Michigan to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Michigan to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Michigan. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Michigan to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Michigan are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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