Cheap flights from Michigan to Knoxville from $57

The month of August is, on average, the cheapest month to fly to Knoxville from Michigan, with most prices found around $169. If you aren’t able to travel during the month of August, then book flights to Knoxville from Michigan during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $172.

The cheapest day to depart from Michigan to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $379. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Michigan to Knoxville for around $473.

In the morning is the cheapest time of day to fly from Michigan to Knoxville when you can find flight prices for as low as $400. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $499.

Fly from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson for the best Michigan - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Michigan when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $470 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Michigan for as low as $346 on momondo.

There are 3 cabin classes available to choose from on Michigan to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, American Airlines, and Delta are the most popular carriers operating from Michigan to Knoxville McGhee Tyson

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Michigan according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

The number of flights available between Michigan and Knoxville is 38 per day as of July 2026. The most frequent departure time is 7:00PM, with 47% of daily flights leaving in the afternoon.

As of July 2026, there are 268 flights per week flying from Michigan to Knoxville. The most common day of the week flights depart is Thu, with 18% of flights taking off on this day.