Cheap flights from Massachusetts to South Carolina from $57

The cheapest month to fly to South Carolina from Massachusetts is in September. Flight prices, which tend to average around $199, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Massachusetts during January instead. Flights to South Carolina in January, while not as cheap as those in September, still average around $207.

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $225. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $338.

Our data shows that the cheapest Massachusetts to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $266. Try not to purchase tickets in the evening because they tend to be around $379. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Boston Logan Intl to Myrtle Beach Intl for the best Massachusetts - South Carolina flight prices

You are more likely to see cheaper flights to South Carolina from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $257 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Massachusetts for as low as $222 on momondo.

There are 4 cabin classes available to choose from on Massachusetts to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, United Airlines, and American Airlines are the most popular carriers operating from Massachusetts to South Carolina

Spirit Airlines, JetBlue and Delta are the top three most popular airlines that fly to South Carolina from Massachusetts according to our data. Spirit Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

As of April 2026, there are 18 flights per day flying from Massachusetts to South Carolina. The most common time of day flights depart is 7:00AM, with 45% of flights taking off in the afternoon.

As of April 2026, there are 132 flights per week flying from Massachusetts to South Carolina. The most common day of the week flights depart is Tue, with 26% of flights taking off on this day.