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Cheap flights from Massachusetts to Florence from $259

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to Florence departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Massachusetts to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:48 am - 10:02 amBOS-FLO
4h 14m1 stop
American Airlines Logo
2:33 pm - 8:09 pmFLO-BOS
5h 36m1 stop
$259American Airlines
Find Deal
Wed, Apr 8 - Tue, Apr 14
American Airlines Logo
10:55 am - 6:05 pmBOS-FLO
7h 10m1 stop
American Airlines Logo
5:15 am - 9:54 amFLO-BOS
4h 39m1 stop
$349American Airlines
Find Deal
Mon, Dec 22 - Wed, Dec 31
American Airlines Logo
6:00 am - 12:26 pmBOS-FLO
6h 26m2 stops
American Airlines Logo
5:15 am - 9:54 amFLO-BOS
4h 39m1 stop
$354American Airlines
Find Deal
Mon, Dec 22 - Wed, Dec 31
American Airlines Logo
5:25 am - 5:09 pmBDL-FLO
11h 44m2 stops
American Airlines Logo
6:15 am - 4:37 pmFLO-BDL
10h 22m2 stops
$408American Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
American Airlines Logo
7:51 am - 2:05 pmBOS-FLO
6h 14m1 stop
American Airlines Logo
2:30 pm - 6:20 pmFLO-BOS
3h 50m1 stop
$433American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:40 am - 10:24 amBOS-FLO
4h 44m1 stop
American Airlines Logo
5:13 am - 11:51 amFLO-BOS
6h 38m2 stops
$438American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
7:00 am - 2:05 pmBOS-FLO
7h 05m2 stops
American Airlines Logo
2:30 pm - 11:35 pmFLO-BOS
9h 05m2 stops
$443American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
3:00 pm - 12:15 amBOS-FLO
9h 15m2 stops
American Airlines Logo
5:15 am - 1:03 pmFLO-BOS
7h 48m2 stops
$449American Airlines
Find Deal
Mon, Dec 22 - Wed, Dec 31
American Airlines Logo
6:29 pm - 10:53 pmALB-FLO
4h 24m1 stop
American Airlines Logo
11:16 am - 4:31 pmFLO-ALB
5h 15m1 stop
$469American Airlines
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Tue, Dec 2 - Sat, Dec 6
American Airlines Logo
5:00 am - 9:54 amBDL-FLO
4h 54m1 stop
American Airlines Logo
6:15 am - 3:40 pmFLO-BDL
9h 25m2 stops
$474American Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9

American Airlines flights from Massachusetts to Florence, South Carolina

Our best American Airlines deals on Massachusetts to Florence, South Carolina flight tickets
American Airlines
Apr 8
BOS5:48 amBoston Logan Intl
4h 14m
1 stop
FLO10:02 amFlorence
Apr 14
FLO2:33 pmFlorence
5h 36m
1 stop
BOS8:09 pmBoston Logan Intl
$259
Find similar
American Airlines
Dec 22
BOS10:55 amBoston Logan Intl
7h 10m
1 stop
FLO6:05 pmFlorence
Dec 31
FLO5:15 amFlorence
4h 39m
1 stop
BOS9:54 amBoston Logan Intl
$349
Find similar
American Airlines
Dec 22
BOS6:00 amBoston Logan Intl
6h 26m
2 stops
FLO12:26 pmFlorence
Dec 31
FLO5:15 amFlorence
4h 39m
1 stop
BOS9:54 amBoston Logan Intl
$354
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Massachusetts to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 4/8

5:48 am-10:02 am

1 stop4h 14m

Florence

Tue 4/14

2:33 pm-8:09 pm

1 stop5h 36m

$259

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/22

10:55 am-6:05 pm

1 stop7h 10m

Florence

Wed 12/31

5:15 am-9:54 am

1 stop4h 39m

$349

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/22

6:00 am-12:26 pm

2 stops6h 26m

Florence

Wed 12/31

5:15 am-9:54 am

1 stop4h 39m

$354

HartfordFlorence

BDL - FLO

BDLFLO

Hartford Bradley Intl

Tue 12/2

5:25 am-5:09 pm

2 stops11h 44m

Florence

Tue 12/9

6:15 am-4:37 pm

2 stops10h 22m

$408

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/25

7:51 am-2:05 pm

1 stop6h 14m

Florence

Sat 3/28

2:30 pm-6:20 pm

1 stop3h 50m

$433

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/25

5:40 am-10:24 am

1 stop4h 44m

Florence

Sat 3/28

5:13 am-11:51 am

2 stops6h 38m

$438

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/25

7:00 am-2:05 pm

2 stops7h 05m

Florence

Sat 3/28

2:30 pm-11:35 pm

2 stops9h 05m

$443

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/22

3:00 pm-12:15 am

2 stops9h 15m

Florence

Wed 12/31

5:15 am-1:03 pm

2 stops7h 48m

$449

AlbanyFlorence

ALB - FLO

ALBFLO

Albany Intl

Tue 12/2

6:29 pm-10:53 pm

1 stop4h 24m

Florence

Sat 12/6

11:16 am-4:31 pm

1 stop5h 15m

$469

HartfordFlorence

BDL - FLO

BDLFLO

Hartford Bradley Intl

Tue 12/2

5:00 am-9:54 am

1 stop4h 54m

Florence

Tue 12/9

6:15 am-3:40 pm

2 stops9h 25m

$474

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Massachusetts to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Massachusetts is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $318. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Massachusetts because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $558.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Massachusetts to Florence, South Carolina in the afternoon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $418 per ticket.

Cheap Massachusetts to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to Florence, South Carolina

Direct flights

None
There are no direct flights from Massachusetts to Florence, South Carolina. There are no popular flight routes from Massachusetts to Florence, South Carolina.
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  • When did momondo last update prices for flights from Massachusetts to Florence Airport?

    Prices for flights from Massachusetts to Florence Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Massachusetts to Florence Airport?

  • How old do you have to be to fly from Massachusetts to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Massachusetts to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Massachusetts to Florence, South Carolina

Compare and see reviews for airlines that fly from Massachusetts to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $392Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to Florence?

Finding the right flight to Florence from Massachusetts is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Massachusetts to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Massachusetts on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Massachusetts to Florence?

Once you have performed a search for Massachusetts to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Massachusetts to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Massachusetts. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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