Cheap flights from Madrid to St. Louis from $415

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to St. Louis departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
British Airways Logo
12:40 pm - 11:12 pm
MAD
-
STL
17h 32m1 stop
British Airways Logo
3:20 pm - 2:15 pm
STL
-
MAD
15h 55m2 stops
$771British Airways
Wed, Jan 14 - Wed, Jan 21
British Airways Logo
1:15 pm - 10:44 pm
MAD
-
STL
16h 29m1 stop
British Airways Logo
1:35 pm - 11:55 am
STL
-
MAD
15h 20m2 stops
$772British Airways
Thu, Jan 15 - Mon, Jan 19
Delta Logo
6:00 am - 7:12 pm
MAD
-
STL
20h 12m2 stops
Delta Logo
10:19 am - 3:20 pm
STL
-
MAD
22h 01m2 stops
$777Delta
Wed, Jan 14 - Wed, Jan 21
Delta Logo
6:00 am - 7:12 pm
MAD
-
STL
20h 12m2 stops
Delta Logo
11:23 am - 11:30 am
STL
-
MAD
17h 07m2 stops
$778Delta
Wed, Jan 14 - Wed, Jan 21
Iberia Logo
12:40 pm - 6:34 pm
MAD
-
STL
12h 54m1 stop
Iberia Logo
11:55 am - 9:25 am
STL
-
MAD
14h 30m1 stop
$779Iberia
Thu, Jan 15 - Mon, Jan 19
Delta Logo
10:00 am - 8:53 am
MAD
-
STL
29h 53m2 stops
Delta Logo
3:45 pm - 5:40 pm
STL
-
MAD
18h 55m2 stops
$782Delta
Mon, Jan 19 - Mon, Jan 26
British Airways Logo
1:15 pm - 10:44 pm
MAD
-
STL
16h 29m1 stop
British Airways Logo
10:17 am - 5:45 am
STL
-
MAD
12h 28m1 stop
$784British Airways
Wed, Jan 14 - Wed, Jan 21
British Airways Logo
12:40 pm - 10:55 pm
MAD
-
STL
17h 15m1 stop
British Airways Logo
11:55 am - 9:25 am
STL
-
MAD
14h 30m1 stop
$785British Airways
Wed, Jan 14 - Wed, Jan 21
Delta Logo
10:00 am - 8:53 am
MAD
-
STL
29h 53m2 stops
Delta Logo
3:45 pm - 9:15 am
STL
-
MAD
10h 30m1 stop
$786Delta
Mon, Jan 19 - Mon, Jan 26
British Airways Logo
1:00 pm - 7:30 pm
MAD
-
STL
13h 30m1 stop
British Airways Logo
2:24 pm - 11:55 am
STL
-
MAD
14h 31m2 stops
$789British Airways
Fri, Feb 27 - Mon, Mar 2

Delta flights from Madrid to St. Louis

Our best Delta deals on Madrid to St. Louis flight tickets
Delta
Jan 14
MAD6:00 amMadrid Barajas
20h 12m
2 stops
STL7:12 pmLambert-St Louis
Jan 21
STL10:19 amLambert-St Louis
22h 01m
2 stops
MAD3:20 pmMadrid Barajas
Delta
Jan 14
MAD6:00 amMadrid Barajas
20h 12m
2 stops
STL7:12 pmLambert-St Louis
Jan 21
STL11:23 amLambert-St Louis
17h 07m
2 stops
MAD11:30 amMadrid Barajas
Delta
Jan 19
MAD10:00 amMadrid Barajas
29h 53m
2 stops
STL8:53 amLambert-St Louis
Jan 26
STL3:45 pmLambert-St Louis
18h 55m
2 stops
MAD5:40 pmMadrid Barajas

Iberia flights from Madrid to St. Louis

Our best Iberia deals on Madrid to St. Louis flight tickets
Iberia
Jan 15
MAD12:40 pmMadrid Barajas
12h 54m
1 stop
STL6:34 pmLambert-St Louis
Jan 19
STL11:55 amLambert-St Louis
14h 30m
1 stop
MAD9:25 amMadrid Barajas
Iberia
Jan 30
MAD1:00 pmMadrid Barajas
16h 59m
1 stop
STL10:59 pmLambert-St Louis
Feb 6
STL9:34 amLambert-St Louis
16h 51m
1 stop
MAD9:25 amMadrid Barajas
Iberia
Feb 1
MAD12:00 pmMadrid Barajas
16h 15m
1 stop
STL9:15 pmLambert-St Louis
Feb 8
STL2:54 pmLambert-St Louis
12h 26m
1 stop
MAD10:20 amMadrid Barajas

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Madrid to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Wed 1/14

12:40 pm-11:12 pm

1 stop17h 32m

Lambert-St Louis

Wed 1/21

3:20 pm-2:15 pm

2 stops15h 55m

$771

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Thu 1/15

1:15 pm-10:44 pm

1 stop16h 29m

Lambert-St Louis

Mon 1/19

1:35 pm-11:55 am

2 stops15h 20m

$772

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Wed 1/14

6:00 am-7:12 pm

2 stops20h 12m

Lambert-St Louis

Wed 1/21

10:19 am-3:20 pm

2 stops22h 01m

$777

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Wed 1/14

6:00 am-7:12 pm

2 stops20h 12m

Lambert-St Louis

Wed 1/21

11:23 am-11:30 am

2 stops17h 07m

$778

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Thu 1/15

12:40 pm-6:34 pm

1 stop12h 54m

Lambert-St Louis

Mon 1/19

11:55 am-9:25 am

1 stop14h 30m

$779

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Mon 1/19

10:00 am-8:53 am

2 stops29h 53m

Lambert-St Louis

Mon 1/26

3:45 pm-5:40 pm

2 stops18h 55m

$782

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Wed 1/14

1:15 pm-10:44 pm

1 stop16h 29m

Lambert-St Louis

Wed 1/21

10:17 am-5:45 am

1 stop12h 28m

$784

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Wed 1/14

12:40 pm-10:55 pm

1 stop17h 15m

Lambert-St Louis

Wed 1/21

11:55 am-9:25 am

1 stop14h 30m

$785

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Mon 1/19

10:00 am-8:53 am

2 stops29h 53m

Lambert-St Louis

Mon 1/26

3:45 pm-9:15 am

1 stop10h 30m

$786

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

Fri 2/27

1:00 pm-7:30 pm

1 stop13h 30m

Lambert-St Louis

Mon 3/2

2:24 pm-11:55 am

2 stops14h 31m

$789

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Madrid to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, April is the cheapest month to fly from Madrid to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $742. The month of May is another great option to travel to St. Louis, with average flight prices from Madrid averaging around $746.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $671. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $1,111. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Madrid at noon is the least expensive time of day to depart. momondo users have found prices as low as $712 when looking at flights departing at noon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $888 per ticket.

Can stopping save me money on Madrid to St. Louis flights?

You could potentially save up to 3% on your flight if you consider stops on a Madrid to St. Louis flight.

When to book flights from Madrid to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to St. Louis (MAD to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to St. Louis

Fastest flight time

17h 32m

Direct flights

None
The fastest flight from Madrid to St. Louis takes 17h 32m
There are no direct flights from Madrid to St. Louis. There are no popular flight routes from Madrid to St. Louis.
  • How far is Madrid Barajas to Lambert-St Louis by plane?

    The distance between Madrid Barajas and Lambert-St Louis is about 4406.9 mi. Typically, this will take 17h 32m by plane in normal conditions.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Lambert-St Louis Airport?

    Prices for flights from Madrid Barajas Airport to Lambert-St Louis Airport were last updated today.

  • How old do you have to be to fly from Madrid Barajas Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The necessary travel and health documents for your Lambert-St Louis Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
St. Peters
Collinsville
Alton
Clayton
Festus
Glencoe
Farmington
Eureka
Edwardsville
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Madrid to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Madrid to St. Louis with flexible booking policies on momondo?

Flights from Madrid to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Madrid to St. Louis?

Once you have performed a search for Madrid to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Madrid to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Madrid to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

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Sat 1/17
Sat 1/24

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