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Cheap flights from Louisville to Greenville from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Greenville departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Louisville to Greenville

Cheap round-trip flights

Southwest Logo
11:45 am - 4:05 pmSDF-GSP
4h 20m1 stop
Southwest Logo
8:20 pm - 12:30 amGSP-SDF
4h 10m1 stop
$247Southwest
Find Deal
Wed, Nov 19 - Wed, Nov 26
Southwest Logo
6:45 am - 7:50 pmSDF-GSP
13h 05m2 stops
Southwest Logo
8:20 pm - 12:30 amGSP-SDF
4h 10m1 stop
$258Southwest
Find Deal
Wed, Nov 19 - Wed, Nov 26
American Airlines Logo
11:57 am - 5:51 pmSDF-GSP
5h 54m1 stop
American Airlines Logo
6:40 pm - 12:22 amGSP-SDF
5h 42m1 stop
$277American Airlines
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Wed, Nov 19 - Wed, Nov 26
American Airlines Logo
4:59 pm - 11:00 pmSDF-GSP
6h 01m2 stops
American Airlines Logo
6:40 pm - 12:22 amGSP-SDF
5h 42m1 stop
$282American Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
Multiple Airlines Logo
7:15 am - 7:23 pmSDF-GSP
12h 08m1 stop
Multiple Airlines Logo
8:03 pm - 9:59 amGSP-SDF
37h 56m2 stops
$284Multiple Airlines
Find Deal
Mon, Oct 27 - Mon, Nov 3
Delta Logo
8:15 pm - 11:55 pmSDF-GSP
3h 40m1 stop
Delta Logo
7:41 pm - 12:01 amGSP-SDF
4h 20m1 stop
$379Delta
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Fri, Oct 10 - Mon, Oct 13
Multiple Airlines Logo
3:15 pm - 2:54 pmSDF-GSP
23h 39m1 stop
Multiple Airlines Logo
8:03 pm - 8:50 pmGSP-SDF
24h 47m1 stop
$380Multiple Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
Delta Logo
8:10 am - 1:29 pmSDF-GSP
5h 19m1 stop
Delta Logo
5:30 am - 8:49 amGSP-SDF
3h 19m1 stop
$407Delta
Find Deal
Fri, Oct 3 - Sun, Oct 5
United Airlines Logo
8:45 am - 10:39 pmSDF-GSP
13h 54m2 stops
United Airlines Logo
3:55 pm - 10:30 pmGSP-SDF
6h 35m1 stop
$573United Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
United Airlines Logo
8:45 am - 10:39 pmSDF-GSP
13h 54m2 stops
United Airlines Logo
5:34 pm - 10:30 pmGSP-SDF
4h 56m1 stop
$623United Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5

Southwest flights from Louisville to Greenville

Our best Southwest deals on Louisville to Greenville flight tickets
Southwest
Nov 19
SDF11:45 amLouisville Intl
4h 20m
1 stop
GSP4:05 pmGreenville
Nov 26
GSP8:20 pmGreenville
4h 10m
1 stop
SDF12:30 amLouisville Intl
$247
Find similar
Southwest
Nov 19
SDF6:45 amLouisville Intl
13h 05m
2 stops
GSP7:50 pmGreenville
Nov 26
GSP8:20 pmGreenville
4h 10m
1 stop
SDF12:30 amLouisville Intl
$258
Find similar
Southwest
Nov 19
SDF6:45 amLouisville Intl
13h 05m
2 stops
GSP7:50 pmGreenville
Nov 26
GSP7:40 amGreenville
14h 10m
2 stops
SDF9:50 pmLouisville Intl
$406
Find similar

United Airlines flights from Louisville to Greenville

Our best United Airlines deals on Louisville to Greenville flight tickets
United Airlines
Oct 3
SDF8:45 amLouisville Intl
13h 54m
2 stops
GSP10:39 pmGreenville
Oct 5
GSP3:55 pmGreenville
6h 35m
1 stop
SDF10:30 pmLouisville Intl
$573
Find similar
United Airlines
Oct 3
SDF8:45 amLouisville Intl
13h 54m
2 stops
GSP10:39 pmGreenville
Oct 5
GSP5:34 pmGreenville
4h 56m
1 stop
SDF10:30 pmLouisville Intl
$623
Find similar
United Airlines
Oct 3
SDF8:45 amLouisville Intl
13h 54m
2 stops
GSP10:39 pmGreenville
Oct 5
GSP6:05 amGreenville
12h 28m
2 stops
SDF6:33 pmLouisville Intl
$740
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 11/19

11:45 am-4:05 pm

1 stop4h 20m

Greenville

Wed 11/26

8:20 pm-12:30 am

1 stop4h 10m

$247

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 11/19

6:45 am-7:50 pm

2 stops13h 05m

Greenville

Wed 11/26

8:20 pm-12:30 am

1 stop4h 10m

$258

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 11/19

11:57 am-5:51 pm

1 stop5h 54m

Greenville

Wed 11/26

6:40 pm-12:22 am

1 stop5h 42m

$277

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 11/19

4:59 pm-11:00 pm

2 stops6h 01m

Greenville

Wed 11/26

6:40 pm-12:22 am

1 stop5h 42m

$282

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 10/27

7:15 am-7:23 pm

1 stop12h 08m

Greenville

Mon 11/3

8:03 pm-9:59 am

2 stops37h 56m

$284

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/10

8:15 pm-11:55 pm

1 stop3h 40m

Greenville

Mon 10/13

7:41 pm-12:01 am

1 stop4h 20m

$379

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 10/4

3:15 pm-2:54 pm

1 stop23h 39m

Greenville

Mon 10/6

8:03 pm-8:50 pm

1 stop24h 47m

$380

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

8:10 am-1:29 pm

1 stop5h 19m

Greenville

Sun 10/5

5:30 am-8:49 am

1 stop3h 19m

$407

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

8:45 am-10:39 pm

2 stops13h 54m

Greenville

Sun 10/5

3:55 pm-10:30 pm

1 stop6h 35m

$573

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

8:45 am-10:39 pm

2 stops13h 54m

Greenville

Sun 10/5

5:34 pm-10:30 pm

1 stop4h 56m

$623

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Louisville to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of April is another great option to travel to Greenville, with average flight prices from Louisville averaging around $276.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Louisville. The lowest ticket price found for a Wednesday departure recently was $331. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $589. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Louisville to Greenville during this time can be as low as $367. Flights to Greenville are more costly in the evening, with an average ticket price of $493. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How have Louisville to Greenville flight prices changed over time?

When to book flights from Louisville to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Greenville (SDF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Greenville

Direct flights

None
There are no direct flights from Louisville to Greenville. There are no popular flight routes from Louisville to Greenville.
Search flight deals

  • How far is Louisville Intl to Greenville by plane?

    A flight from Louisville Intl to Greenville will travel around 299.5 mi. In terms of flight time, this usually takes a little over 3h 40m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Greenville Airport?

    Prices for flights from Louisville Intl Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Greenville?

Best airlines flying from Louisville to Greenville

Compare and see reviews for airlines that fly from Louisville to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $190Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $196Free CancellationRating
7.9
7,961 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Louisville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Louisville to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Greenville.

I’m not ready to book a flight from Louisville to Greenville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Greenville, momondo offers a useful price alert feature which will track prices for flights to Greenville from Louisville and alert you when they change.

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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