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Cheap flights from Louisville to Greenville from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Greenville departing on 5/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:32 pm - 9:15 pm
SDF
-
GSP
6h 43m
1 stop
American Airlines Logo
7:32 pm - 12:28 am
GSP
-
SDF
4h 56m
1 stop
$311American Airlines
Thu, May 28 - Mon, Jun 1
Southwest Logo
7:25 am - 12:15 pm
SDF
-
GSP
4h 50m
1 stop
Southwest Logo
7:30 pm - 11:10 pm
GSP
-
SDF
3h 40m
1 stop
$327Southwest
Tue, Jun 23 - Sun, Jun 28
American Airlines Logo
8:12 pm - 11:27 pm
SDF
-
GSP
3h 15m
1 stop
American Airlines Logo
8:20 pm - 12:16 am
GSP
-
SDF
3h 56m
1 stop
$329American Airlines
Thu, Aug 27 - Sun, Aug 30
Southwest Logo
8:45 am - 7:00 pm
SDF
-
GSP
10h 15m
2 stops
Southwest Logo
7:30 pm - 11:10 pm
GSP
-
SDF
3h 40m
1 stop
$332Southwest
Tue, Jun 23 - Sun, Jun 28
American Airlines Logo
5:00 am - 8:18 am
SDF
-
GSP
3h 18m
1 stop
American Airlines Logo
7:32 pm - 12:28 am
GSP
-
SDF
4h 56m
1 stop
$347American Airlines
Tue, Jun 2 - Fri, Jun 5
Southwest Logo
3:30 pm - 9:40 pm
SDF
-
GSP
6h 10m
2 stops
Southwest Logo
1:55 pm - 12:25 am
GSP
-
SDF
10h 30m
1 stop
$358Southwest
Tue, Jun 2 - Fri, Jun 5
American Airlines Logo
5:00 am - 8:18 am
SDF
-
GSP
3h 18m
1 stop
American Airlines Logo
7:32 pm - 12:28 am
GSP
-
SDF
4h 56m
1 stop
$359American Airlines
Tue, Jun 23 - Sun, Jun 28
Southwest Logo
8:55 am - 8:00 pm
SDF
-
GSP
11h 05m
2 stops
Southwest Logo
12:55 pm - 9:55 pm
GSP
-
SDF
9h 00m
2 stops
$367Southwest
Tue, Jun 2 - Fri, Jun 5
United Airlines Logo
10:15 am - 5:02 pm
SDF
-
GSP
6h 47m
1 stop
United Airlines Logo
5:43 pm - 10:22 pm
GSP
-
SDF
4h 39m
1 stop
$377United Airlines
Tue, Aug 18 - Wed, Aug 19
United Airlines Logo
10:05 am - 7:45 pm
SDF
-
GSP
9h 40m
2 stops
United Airlines Logo
5:43 pm - 10:22 pm
GSP
-
SDF
4h 39m
1 stop
$382United Airlines
Tue, Aug 18 - Wed, Aug 19

Southwest flights from Louisville to Greenville

Our best Southwest deals on Louisville to Greenville flight tickets
Southwest
Jun 23
SDF7:25 amLouisville Intl
4h 50m
1 stop
GSP12:15 pmGreenville
Jun 28
GSP7:30 pmGreenville
3h 40m
1 stop
SDF11:10 pmLouisville Intl
$327
Southwest
Jun 23
SDF8:45 amLouisville Intl
10h 15m
2 stops
GSP7:00 pmGreenville
Jun 28
GSP7:30 pmGreenville
3h 40m
1 stop
SDF11:10 pmLouisville Intl
$332
Southwest
Jun 2
SDF3:30 pmLouisville Intl
6h 10m
2 stops
GSP9:40 pmGreenville
Jun 5
GSP1:55 pmGreenville
10h 30m
1 stop
SDF12:25 amLouisville Intl
$358

United Airlines flights from Louisville to Greenville

Our best United Airlines deals on Louisville to Greenville flight tickets
United Airlines
Aug 18
SDF10:15 amLouisville Intl
6h 47m
1 stop
GSP5:02 pmGreenville
Aug 19
GSP5:43 pmGreenville
4h 39m
1 stop
SDF10:22 pmLouisville Intl
$377
United Airlines
Aug 18
SDF10:05 amLouisville Intl
9h 40m
2 stops
GSP7:45 pmGreenville
Aug 19
GSP5:43 pmGreenville
4h 39m
1 stop
SDF10:22 pmLouisville Intl
$382
United Airlines
Aug 18
SDF10:05 amLouisville Intl
9h 40m
2 stops
GSP7:45 pmGreenville
Aug 19
GSP7:00 amGreenville
7h 41m
2 stops
SDF2:41 pmLouisville Intl
$387

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 5/28

2:32 pm-9:15 pm

1 stop6h 43m

Greenville

Mon 6/1

7:32 pm-12:28 am

1 stop4h 56m

$311

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/23

7:25 am-12:15 pm

1 stop4h 50m

Greenville

Sun 6/28

7:30 pm-11:10 pm

1 stop3h 40m

$327
Quickest round-trip

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 8/27

8:12 pm-11:27 pm

1 stop3h 15m

Greenville

Sun 8/30

8:20 pm-12:16 am

1 stop3h 56m

$329

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/23

8:45 am-7:00 pm

2 stops10h 15m

Greenville

Sun 6/28

7:30 pm-11:10 pm

1 stop3h 40m

$332

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/2

5:00 am-8:18 am

1 stop3h 18m

Greenville

Fri 6/5

7:32 pm-12:28 am

1 stop4h 56m

$347

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/2

3:30 pm-9:40 pm

2 stops6h 10m

Greenville

Fri 6/5

1:55 pm-12:25 am

1 stop10h 30m

$358

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/23

5:00 am-8:18 am

1 stop3h 18m

Greenville

Sun 6/28

7:32 pm-12:28 am

1 stop4h 56m

$359

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 6/2

8:55 am-8:00 pm

2 stops11h 05m

Greenville

Fri 6/5

12:55 pm-9:55 pm

2 stops9h 00m

$367

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 8/18

10:15 am-5:02 pm

1 stop6h 47m

Greenville

Wed 8/19

5:43 pm-10:22 pm

1 stop4h 39m

$377

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 8/18

10:05 am-7:45 pm

2 stops9h 40m

Greenville

Wed 8/19

5:43 pm-10:22 pm

1 stop4h 39m

$382

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Louisville to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Louisville averaging around $246.

When to book flights from Louisville to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Greenville (SDF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Greenville

Fastest flight time

3h 24m

Direct flights

None
The fastest flight from Louisville to Greenville takes 3h 24m
There are no direct flights from Louisville to Greenville. There are no popular flight routes from Louisville to Greenville.
Search flight deals

Frequently asked questions about flying from Louisville to Greenville

  • How far is Louisville Intl to Greenville by plane?

    A flight from Louisville Intl to Greenville will travel around 299.5 mi. In terms of flight time, this usually takes a little over 3h 24m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Greenville Airport?

    Prices for flights from Louisville Intl Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Greenville?

Best airlines flying from Louisville to Greenville

Compare and see reviews for airlines that fly from Louisville to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $153Free CancellationRating
7.9
8,454 reviews
Search Delta flights
American AirlinesPriceFrom $183Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Louisville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Louisville to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Greenville.

I’m not ready to book a flight from Louisville to Greenville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Greenville, momondo offers a useful price alert feature which will track prices for flights to Greenville from Louisville and alert you when they change.

An easier way to manage your Greenville trip

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