Cheap flights from Louisville to Greenville from $274

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Greenville departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:30 am - 10:10 am
SDF
-
GSP
4h 40m1 stop
Southwest Logo
8:00 am - 12:40 pm
GSP
-
SDF
4h 40m1 stop
$274Southwest
Thu, Feb 26 - Sat, Feb 28
Southwest Logo
5:30 am - 7:05 pm
SDF
-
GSP
13h 35m2 stops
Southwest Logo
8:00 am - 12:40 pm
GSP
-
SDF
4h 40m1 stop
$285Southwest
Thu, Feb 26 - Sat, Feb 28
Southwest Logo
5:25 pm - 9:45 pm
SDF
-
GSP
4h 20m1 stop
Southwest Logo
8:00 am - 12:45 pm
GSP
-
SDF
4h 45m1 stop
$289Southwest
Sun, Mar 8 - Tue, Mar 10
Southwest Logo
5:35 pm - 11:25 pm
SDF
-
GSP
5h 50m1 stop
Southwest Logo
1:50 pm - 10:15 pm
GSP
-
SDF
8h 25m2 stops
$294Southwest
Sun, Mar 8 - Tue, Mar 10
Southwest Logo
5:30 am - 7:05 pm
SDF
-
GSP
13h 35m2 stops
Southwest Logo
8:00 am - 8:30 pm
GSP
-
SDF
12h 30m2 stops
$295Southwest
Thu, Feb 26 - Sat, Feb 28
Southwest Logo
8:45 am - 6:40 pm
SDF
-
GSP
9h 55m2 stops
Southwest Logo
8:00 am - 3:55 pm
GSP
-
SDF
7h 55m2 stops
$299Southwest
Sun, Mar 8 - Tue, Mar 10
United Airlines Logo
9:50 am - 2:19 pm
SDF
-
GSP
4h 29m1 stop
United Airlines Logo
10:00 am - 2:48 pm
GSP
-
SDF
4h 48m1 stop
$341United Airlines
Mon, Jan 12 - Thu, Jan 15
United Airlines Logo
2:05 pm - 8:47 pm
SDF
-
GSP
6h 42m1 stop
United Airlines Logo
10:00 am - 5:37 pm
GSP
-
SDF
7h 37m2 stops
$346United Airlines
Mon, Jan 12 - Thu, Jan 15
United Airlines Logo
11:10 am - 4:52 pm
SDF
-
GSP
5h 42m1 stop
United Airlines Logo
6:20 am - 1:05 pm
GSP
-
SDF
6h 45m1 stop
$351United Airlines
Mon, Jan 12 - Thu, Jan 15
United Airlines Logo
11:10 am - 4:52 pm
SDF
-
GSP
5h 42m1 stop
United Airlines Logo
10:00 am - 5:37 pm
GSP
-
SDF
7h 37m2 stops
$356United Airlines
Mon, Jan 12 - Thu, Jan 15

United Airlines flights from Louisville to Greenville

Our best United Airlines deals on Louisville to Greenville flight tickets
United Airlines
Jan 12
SDF9:50 amLouisville Intl
4h 29m
1 stop
GSP2:19 pmGreenville
Jan 15
GSP10:00 amGreenville
4h 48m
1 stop
SDF2:48 pmLouisville Intl
United Airlines
Jan 12
SDF11:10 amLouisville Intl
12h 38m
2 stops
GSP11:48 pmGreenville
Jan 15
GSP6:35 amGreenville
6h 49m
1 stop
SDF1:24 pmLouisville Intl
United Airlines
Jan 12
SDF11:10 amLouisville Intl
5h 42m
1 stop
GSP4:52 pmGreenville
Jan 15
GSP6:20 amGreenville
6h 45m
1 stop
SDF1:05 pmLouisville Intl

American Airlines flights from Louisville to Greenville

Our best American Airlines deals on Louisville to Greenville flight tickets
American Airlines
Dec 30
SDF6:03 amLouisville Intl
6h 16m
2 stops
GSP12:19 pmGreenville
Jan 2
GSP6:20 pmGreenville
5h 56m
1 stop
SDF12:16 amLouisville Intl
American Airlines
Dec 19
SDF5:00 amLouisville Intl
5h 11m
1 stop
GSP10:11 amGreenville
Dec 19
GSP12:44 pmGreenville
5h 48m
1 stop
SDF6:32 pmLouisville Intl

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 2/26

5:30 am-10:10 am

1 stop4h 40m

Greenville

Sat 2/28

8:00 am-12:40 pm

1 stop4h 40m

$274

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 2/26

5:30 am-7:05 pm

2 stops13h 35m

Greenville

Sat 2/28

8:00 am-12:40 pm

1 stop4h 40m

$285

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 3/8

5:25 pm-9:45 pm

1 stop4h 20m

Greenville

Tue 3/10

8:00 am-12:45 pm

1 stop4h 45m

$289

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 3/8

5:35 pm-11:25 pm

1 stop5h 50m

Greenville

Tue 3/10

1:50 pm-10:15 pm

2 stops8h 25m

$294

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 2/26

5:30 am-7:05 pm

2 stops13h 35m

Greenville

Sat 2/28

8:00 am-8:30 pm

2 stops12h 30m

$295

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 3/8

8:45 am-6:40 pm

2 stops9h 55m

Greenville

Tue 3/10

8:00 am-3:55 pm

2 stops7h 55m

$299

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 1/12

9:50 am-2:19 pm

1 stop4h 29m

Greenville

Thu 1/15

10:00 am-2:48 pm

1 stop4h 48m

$341

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 1/12

2:05 pm-8:47 pm

1 stop6h 42m

Greenville

Thu 1/15

10:00 am-5:37 pm

2 stops7h 37m

$346

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 1/12

11:10 am-4:52 pm

1 stop5h 42m

Greenville

Thu 1/15

6:20 am-1:05 pm

1 stop6h 45m

$351

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 1/12

11:10 am-4:52 pm

1 stop5h 42m

Greenville

Thu 1/15

10:00 am-5:37 pm

2 stops7h 37m

$356

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Greenville from

How to get the cheapest flight ticket from Louisville to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of June is another great option to travel to Greenville, with average flight prices from Louisville averaging around $254.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Louisville. The lowest ticket price found for a Wednesday departure recently was $331. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $589. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Louisville to Greenville during this time can be as low as $367. Flights to Greenville are more costly in the evening, with an average ticket price of $493. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Louisville to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Greenville (SDF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Greenville

Fastest flight time

3h 19m

Direct flights

None
The fastest flight from Louisville to Greenville takes 3h 19m
There are no direct flights from Louisville to Greenville. There are no popular flight routes from Louisville to Greenville.
  • How far is Louisville Intl to Greenville by plane?

    A flight from Louisville Intl to Greenville will travel around 299.5 mi. In terms of flight time, this usually takes a little over 3h 19m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Greenville Airport?

    Prices for flights from Louisville Intl Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Greenville?

Best airlines flying from Louisville to Greenville

Compare and see reviews for airlines that fly from Louisville to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $190Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
DeltaPriceFrom $196Free CancellationRating
7.9
8,005 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Louisville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Louisville to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Greenville.

I’m not ready to book a flight from Louisville to Greenville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Greenville, momondo offers a useful price alert feature which will track prices for flights to Greenville from Louisville and alert you when they change.

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1 adult
Sat 1/17
Sat 1/24

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