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Cheap flights from Louisiana to Knoxville from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Logo
9:12 am - 5:06 pmMSY-TYS
6h 54m1 stop
Logo
7:20 am - 4:04 pmTYS-MSY
9h 44m1 stop
$199
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Fri, Oct 3 - Sun, Oct 5
Logo
8:50 am - 10:18 amMSY-TYS
24h 28m2 stops
Logo
7:20 am - 8:29 pmTYS-MSY
14h 09m1 stop
$224
Find Deal
Fri, Oct 3 - Sun, Oct 5
Logo
6:30 am - 3:36 pmMSY-TYS
8h 06m1 stop
Logo
9:01 pm - 8:07 amTYS-MSY
12h 06m1 stop
$237
Find Deal
Wed, Oct 15 - Sun, Oct 19
Logo
9:12 am - 8:11 pmMSY-TYS
9h 59m1 stop
Logo
9:01 pm - 8:07 amTYS-MSY
12h 06m1 stop
$241
Find Deal
Thu, Oct 16 - Sun, Oct 19
Delta Logo
11:00 am - 6:13 pmLFT-TYS
6h 13m1 stop
Delta Logo
6:10 pm - 8:59 pmTYS-LFT
3h 49m1 stop
$249Delta
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Wed, Dec 3 - Sat, Dec 6
American Airlines Logo
7:50 am - 3:41 pmSHV-TYS
6h 51m1 stop
American Airlines Logo
6:00 am - 9:43 amTYS-SHV
4h 43m1 stop
$249American Airlines
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Tue, Sep 9 - Sat, Sep 20
American Airlines Logo
5:15 am - 11:23 amMSY-TYS
5h 08m1 stop
American Airlines Logo
6:18 pm - 10:51 pmTYS-MSY
5h 33m1 stop
$249American Airlines
Find Deal
Thu, Nov 20 - Sun, Nov 23
Delta Logo
5:03 pm - 11:48 pmMSY-TYS
5h 45m1 stop
Delta Logo
5:45 am - 8:00 amTYS-MSY
3h 15m1 stop
$254Delta
Find Deal
Sat, Sep 6 - Thu, Sep 11
United Airlines Logo
2:20 pm - 10:45 pmMSY-TYS
7h 25m1 stop
United Airlines Logo
9:30 am - 4:00 pmTYS-MSY
7h 30m1 stop
$324United Airlines
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Sat, Sep 6 - Sat, Sep 13
United Airlines Logo
5:18 pm - 11:43 pmMSY-TYS
5h 25m1 stop
United Airlines Logo
7:00 am - 1:33 pmTYS-MSY
7h 33m1 stop
$359United Airlines
Find Deal
Mon, Sep 29 - Tue, Sep 30

Delta flights from Louisiana to Knoxville

Our best Delta deals on Louisiana to Knoxville flight tickets
Delta
Dec 3
LFT11:00 amLafayette Regional
6h 13m
1 stop
TYS6:13 pmKnoxville McGhee Tyson
Dec 6
TYS6:10 pmKnoxville McGhee Tyson
3h 49m
1 stop
LFT8:59 pmLafayette Regional
$249
Find similar
Delta
Sep 6
MSY5:03 pmNew Orleans Louis Armstrong
5h 45m
1 stop
TYS11:48 pmKnoxville McGhee Tyson
Sep 11
TYS5:45 amKnoxville McGhee Tyson
3h 15m
1 stop
MSY8:00 amNew Orleans Louis Armstrong
$254
Find similar
Delta
Oct 4
SHV5:15 pmShreveport
5h 29m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Oct 10
TYS8:10 pmKnoxville McGhee Tyson
4h 12m
1 stop
SHV11:22 pmShreveport
$274
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American Airlines flights from Louisiana to Knoxville

Our best American Airlines deals on Louisiana to Knoxville flight tickets
American Airlines
Sep 27
BTR5:38 pmBaton Rouge Ryan
4h 25m
1 stop
TYS11:03 pmKnoxville McGhee Tyson
Oct 4
TYS7:45 pmKnoxville McGhee Tyson
4h 21m
1 stop
BTR11:06 pmBaton Rouge Ryan
$249
Find similar
American Airlines
Sep 6
LFT4:22 pmLafayette Regional
6h 59m
1 stop
TYS12:21 amKnoxville McGhee Tyson
Sep 13
TYS6:00 amKnoxville McGhee Tyson
6h 41m
1 stop
LFT11:41 amLafayette Regional
$254
Find similar
American Airlines
Sep 5
MSY3:16 pmNew Orleans Louis Armstrong
5h 25m
1 stop
TYS9:41 pmKnoxville McGhee Tyson
Sep 7
TYS8:36 pmKnoxville McGhee Tyson
4h 39m
1 stop
MSY12:15 amNew Orleans Louis Armstrong
$259
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 10/3

9:12 am-5:06 pm

1 stop6h 54m

Knoxville McGhee Tyson

Sun 10/5

7:20 am-4:04 pm

1 stop9h 44m

$199

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 10/3

8:50 am-10:18 am

2 stops24h 28m

Knoxville McGhee Tyson

Sun 10/5

7:20 am-8:29 pm

1 stop14h 09m

$224

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 10/15

6:30 am-3:36 pm

1 stop8h 06m

Knoxville McGhee Tyson

Sun 10/19

9:01 pm-8:07 am

1 stop12h 06m

$237

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 10/16

9:12 am-8:11 pm

1 stop9h 59m

Knoxville McGhee Tyson

Sun 10/19

9:01 pm-8:07 am

1 stop12h 06m

$241

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 12/3

11:00 am-6:13 pm

1 stop6h 13m

Knoxville McGhee Tyson

Sat 12/6

6:10 pm-8:59 pm

1 stop3h 49m

$249

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Tue 9/9

7:50 am-3:41 pm

1 stop6h 51m

Knoxville McGhee Tyson

Sat 9/20

6:00 am-9:43 am

1 stop4h 43m

$249

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 11/20

5:15 am-11:23 am

1 stop5h 08m

Knoxville McGhee Tyson

Sun 11/23

6:18 pm-10:51 pm

1 stop5h 33m

$249

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 9/6

5:03 pm-11:48 pm

1 stop5h 45m

Knoxville McGhee Tyson

Thu 9/11

5:45 am-8:00 am

1 stop3h 15m

$254

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 9/6

2:20 pm-10:45 pm

1 stop7h 25m

Knoxville McGhee Tyson

Sat 9/13

9:30 am-4:00 pm

1 stop7h 30m

$324

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 9/29

5:18 pm-11:43 pm

1 stop5h 25m

Knoxville McGhee Tyson

Tue 9/30

7:00 am-1:33 pm

1 stop7h 33m

$359

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $263. If you aren’t able to travel during the month of July, then book flights to Knoxville from Louisiana during January instead. Flights to Knoxville in January, while not as cheap as those in July, still average around $275.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Louisiana to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $314. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Louisiana to Knoxville for around $403.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Louisiana to Knoxville when you can find flight prices for as low as $321. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $365.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $329 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $268 on momondo.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Direct flights

None
There are no direct flights from Louisiana to Knoxville. There are no popular flight routes from Louisiana to Knoxville.
Search flight deals

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $104Free CancellationRating
7.9
7,982 reviews
Search Delta flights
United AirlinesPriceFrom $198Free CancellationRating
7.4
8,928 reviews
Search United Airlines flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Lenoir City
Alcoa
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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