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Cheap flights from Louisiana to Knoxville from $96

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:25 am - 10:54 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
3h 29m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:23 pm - 11:35 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 12m1 stop Atlanta Hartsfield-Jackson
$199Delta
Tue, Oct 20 - Wed, Oct 21
Southwest Logo
6:30 am - 1:05 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 35m1 stop Orlando
Southwest Logo
5:45 pm - 10:30 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 45m1 stop Nashville Intl
$216Southwest
Wed, Sep 16 - Thu, Sep 17
Southwest Logo
7:00 am - 12:55 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 55m1 stop Austin Bergstrom
Southwest Logo
7:25 pm - 11:55 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 30m1 stop Nashville Intl
$216Southwest
Sat, Oct 24 - Thu, Oct 29
Delta Logo
5:20 am - 10:45 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 25m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:34 pm - 4:57 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 23m1 stop Atlanta Hartsfield-Jackson
$233Delta
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
5:49 am - 12:53 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 04m1 stop Dallas/Fort Worth
American Airlines Logo
6:06 pm - 9:14 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
4h 08m1 stop Charlotte Douglas
$239American Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
5:41 am - 12:56 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 15m1 stop Dallas/Fort Worth
American Airlines Logo
7:00 am - 1:12 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
7h 12m1 stop Charlotte Douglas
$249American Airlines
Tue, Sep 1 - Sat, Sep 5
Multiple Airlines Logo
5:49 pm - 7:45 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
12h 56m1 stop Tampa
Multiple Airlines Logo
2:21 pm - 4:03 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
26h 42m2 stops Philadelphia Atlanta Hartsfield-Jackson
$250Multiple Airlines
Thu, Nov 12 - Mon, Nov 16
Multiple Airlines Logo
9:40 am - 9:56 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
11h 16m1 stop Jacksonville
Multiple Airlines Logo
5:44 pm - 4:03 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
23h 19m2 stops Orlando Sanford Intl Atlanta Hartsfield-Jackson
$253Multiple Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
7:00 am - 1:17 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
3:40 pm - 8:03 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 23m1 stop Houston George Bush Intcntl
$287United Airlines
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
7:00 am - 1:20 pmLFT  Lafayette Regional-TYS Knoxville McGhee Tyson
5h 20m1 stop Houston George Bush Intcntl
United Airlines Logo
12:15 pm - 3:29 pmTYS  Knoxville McGhee Tyson-LFT Lafayette Regional
4h 14m1 stop Houston George Bush Intcntl
$295United Airlines
Sun, Sep 6 - Sat, Sep 12

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Southwest flights from Louisiana to Knoxville

Our best Southwest deals on Louisiana to Knoxville flight tickets
Southwest
Oct 24
MSY7:00 amNew Orleans Louis Armstrong
4h 55m
1 stop
TYS12:55 pmKnoxville McGhee Tyson
Oct 29
TYS7:25 pmKnoxville McGhee Tyson
5h 30m
1 stop
MSY11:55 pmNew Orleans Louis Armstrong
$216
Southwest
Oct 24
MSY10:15 amNew Orleans Louis Armstrong
8h 20m
2 stops
TYS7:35 pmKnoxville McGhee Tyson
Oct 29
TYS7:25 pmKnoxville McGhee Tyson
5h 30m
1 stop
MSY11:55 pmNew Orleans Louis Armstrong
$221
Southwest
Sep 6
MSY6:15 amNew Orleans Louis Armstrong
10h 05m
1 stop
TYS5:20 pmKnoxville McGhee Tyson
Sep 12
TYS6:50 amKnoxville McGhee Tyson
3h 30m
1 stop
MSY9:20 amNew Orleans Louis Armstrong
$245

American Airlines flights from Louisiana to Knoxville

Our best American Airlines deals on Louisiana to Knoxville flight tickets
American Airlines
Sep 10
MSY5:49 amNew Orleans Louis Armstrong
6h 04m
1 stop
TYS12:53 pmKnoxville McGhee Tyson
Sep 17
TYS6:06 pmKnoxville McGhee Tyson
4h 08m
1 stop
MSY9:14 pmNew Orleans Louis Armstrong
$239
American Airlines
Sep 1
MSY5:41 amNew Orleans Louis Armstrong
6h 15m
1 stop
TYS12:56 pmKnoxville McGhee Tyson
Sep 5
TYS7:00 amKnoxville McGhee Tyson
7h 12m
1 stop
MSY1:12 pmNew Orleans Louis Armstrong
$249
American Airlines
Aug 31
MSY8:01 amNew Orleans Louis Armstrong
7h 42m
1 stop
TYS4:43 pmKnoxville McGhee Tyson
Sep 5
TYS6:50 pmKnoxville McGhee Tyson
5h 09m
1 stop
MSY10:59 pmNew Orleans Louis Armstrong
$272

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Tue 10/20

6:25 am-10:54 am

1 stop3h 29m

Knoxville McGhee Tyson

Wed 10/21

6:23 pm-11:35 pm

1 stop6h 12m

$199

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Wed 9/16

6:30 am-1:05 pm

1 stop5h 35m

Knoxville McGhee Tyson

Thu 9/17

5:45 pm-10:30 pm

1 stop5h 45m

$216

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Sat 10/24

7:00 am-12:55 pm

1 stop4h 55m

Knoxville McGhee Tyson

Thu 10/29

7:25 pm-11:55 pm

1 stop5h 30m

$216

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Fri 11/6

5:20 am-10:45 am

1 stop4h 25m

Knoxville McGhee Tyson

Tue 11/10

12:34 pm-4:57 pm

1 stop5h 23m

$233

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Thu 9/10

5:49 am-12:53 pm

1 stop6h 04m

Knoxville McGhee Tyson

Thu 9/17

6:06 pm-9:14 pm

1 stop4h 08m

$239

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Tue 9/1

5:41 am-12:56 pm

1 stop6h 15m

Knoxville McGhee Tyson

Sat 9/5

7:00 am-1:12 pm

1 stop7h 12m

$249

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Thu 11/12

5:49 pm-7:45 am

1 stop12h 56m

Knoxville McGhee Tyson

Mon 11/16

2:21 pm-4:03 pm

2 stops26h 42m

$250

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Thu 10/29

9:40 am-9:56 pm

1 stop11h 16m

Knoxville McGhee Tyson

Mon 11/2

5:44 pm-4:03 pm

2 stops23h 19m

$253

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Tue 9/1

7:00 am-1:17 pm

1 stop5h 17m

Knoxville McGhee Tyson

Sat 9/5

3:40 pm-8:03 pm

1 stop5h 23m

$287
Quickest round-trip

LafayetteKnoxville

LFT Lafayette Regional - TYS Knoxville McGhee Tyson

LFTTYS

Lafayette Regional

Sun 9/6

7:00 am-1:20 pm

1 stop5h 20m

Knoxville McGhee Tyson

Sat 9/12

12:15 pm-3:29 pm

1 stop4h 14m

$295

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $364. If you aren’t able to travel during the month of February, then book flights to Knoxville from Louisiana during August instead. Flights to Knoxville in August, while not as cheap as those in February, still average around $380.

How far in advance should I book a flight from Louisiana to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $313 on momondo.

Can stopping save me money on Louisiana to Knoxville flights?

You could potentially save up to 61% on your flight if you consider stops on a Louisiana to Knoxville flight.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Fastest flight time

1h 40m

Direct flights

Sat

Airports in Knoxville

1 airport
The fastest flight from Louisiana to Knoxville takes 1h 40m
Direct flights go from Louisiana to Knoxville on Saturday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From Louisiana there are direct flights to Knoxville McGhee Tyson (TYS).
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Frequently asked questions about flying from Louisiana to Knoxville

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,911 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.8
8,505 reviews
Search Delta flights
SouthwestPriceFrom $294Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
United AirlinesPriceFrom $336Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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