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Cheap flights from Louisiana to Knoxville from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:11 pm - 11:05 pm
MSY
-
TYS
4h 54m1 stop
Multiple Airlines Logo
9:29 am - 8:21 am
TYS
-
MSY
23h 52m1 stop
$208Multiple Airlines
Thu, Jan 29 - Sun, Feb 1
Multiple Airlines Logo
6:20 am - 4:59 pm
MSY
-
TYS
9h 39m1 stop
Multiple Airlines Logo
3:50 pm - 8:55 pm
TYS
-
MSY
6h 05m1 stop
$211Multiple Airlines
Mon, Feb 23 - Wed, Feb 25
American Airlines Logo
6:45 pm - 11:54 pm
MSY
-
TYS
4h 09m1 stop
American Airlines Logo
5:35 am - 9:51 am
TYS
-
MSY
5h 16m1 stop
$235American Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
9:50 am - 6:05 pm
LFT
-
TYS
7h 15m1 stop
United Airlines Logo
4:55 pm - 9:36 pm
TYS
-
LFT
5h 41m1 stop
$249United Airlines
Wed, Jan 7 - Wed, Jan 14
Delta Logo
6:18 am - 1:50 pm
BTR
-
TYS
6h 32m1 stop
Delta Logo
5:40 am - 9:52 am
TYS
-
BTR
5h 12m1 stop
$249Delta
Sat, Jan 24 - Sun, Jan 25
American Airlines Logo
10:30 am - 11:59 pm
LFT
-
TYS
12h 29m2 stops
American Airlines Logo
6:51 pm - 10:57 pm
TYS
-
LFT
5h 06m1 stop
$254American Airlines
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
10:30 am - 11:59 pm
LFT
-
TYS
12h 29m2 stops
American Airlines Logo
6:00 am - 2:20 pm
TYS
-
LFT
9h 20m2 stops
$259American Airlines
Wed, Jan 7 - Wed, Jan 14
Multiple Airlines Logo
3:01 pm - 9:37 pm
MSY
-
TYS
5h 36m1 stop
Multiple Airlines Logo
8:30 am - 8:21 am
TYS
-
MSY
24h 51m1 stop
$261Multiple Airlines
Mon, Jan 5 - Mon, Jan 19
Delta Logo
11:50 am - 5:16 pm
MSY
-
TYS
4h 26m1 stop
Delta Logo
6:10 pm - 11:30 pm
TYS
-
MSY
6h 20m1 stop
$277Delta
Tue, Jan 6 - Wed, Jan 7
United Airlines Logo
4:10 pm - 11:44 pm
SHV
-
TYS
6h 34m1 stop
United Airlines Logo
4:55 pm - 9:17 pm
TYS
-
SHV
5h 22m1 stop
$319United Airlines
Sat, Jan 31 - Wed, Feb 4

Delta flights from Louisiana to Knoxville

Our best Delta deals on Louisiana to Knoxville flight tickets
Delta
Jan 24
BTR6:18 amBaton Rouge Ryan
6h 32m
1 stop
TYS1:50 pmKnoxville McGhee Tyson
Jan 25
TYS5:40 amKnoxville McGhee Tyson
5h 12m
1 stop
BTR9:52 amBaton Rouge Ryan
$249
Find similar
Delta
Jan 6
MSY11:50 amNew Orleans Louis Armstrong
4h 26m
1 stop
TYS5:16 pmKnoxville McGhee Tyson
Jan 7
TYS6:10 pmKnoxville McGhee Tyson
6h 20m
1 stop
MSY11:30 pmNew Orleans Louis Armstrong
$277
Find similar
Delta
Feb 5
LFT5:17 pmLafayette Regional
5h 28m
1 stop
TYS11:45 pmKnoxville McGhee Tyson
Feb 9
TYS5:40 amKnoxville McGhee Tyson
6h 01m
1 stop
LFT10:41 amLafayette Regional
$279
Find similar

American Airlines flights from Louisiana to Knoxville

Our best American Airlines deals on Louisiana to Knoxville flight tickets
American Airlines
Feb 14
MSY6:45 pmNew Orleans Louis Armstrong
4h 09m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Feb 18
TYS5:35 amKnoxville McGhee Tyson
5h 16m
1 stop
MSY9:51 amNew Orleans Louis Armstrong
$235
Find similar
American Airlines
Jan 7
LFT10:30 amLafayette Regional
12h 29m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
Jan 14
TYS6:51 pmKnoxville McGhee Tyson
5h 06m
1 stop
LFT10:57 pmLafayette Regional
$254
Find similar
American Airlines
Jan 7
LFT10:30 amLafayette Regional
12h 29m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
Jan 14
TYS6:00 amKnoxville McGhee Tyson
9h 20m
2 stops
LFT2:20 pmLafayette Regional
$259
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 1/29

5:11 pm-11:05 pm

1 stop4h 54m

Knoxville McGhee Tyson

Sun 2/1

9:29 am-8:21 am

1 stop23h 52m

$208

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 2/23

6:20 am-4:59 pm

1 stop9h 39m

Knoxville McGhee Tyson

Wed 2/25

3:50 pm-8:55 pm

1 stop6h 05m

$211

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 2/14

6:45 pm-11:54 pm

1 stop4h 09m

Knoxville McGhee Tyson

Wed 2/18

5:35 am-9:51 am

1 stop5h 16m

$235

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 1/7

9:50 am-6:05 pm

1 stop7h 15m

Knoxville McGhee Tyson

Wed 1/14

4:55 pm-9:36 pm

1 stop5h 41m

$249

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Sat 1/24

6:18 am-1:50 pm

1 stop6h 32m

Knoxville McGhee Tyson

Sun 1/25

5:40 am-9:52 am

1 stop5h 12m

$249

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 1/7

10:30 am-11:59 pm

2 stops12h 29m

Knoxville McGhee Tyson

Wed 1/14

6:51 pm-10:57 pm

1 stop5h 06m

$254

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 1/7

10:30 am-11:59 pm

2 stops12h 29m

Knoxville McGhee Tyson

Wed 1/14

6:00 am-2:20 pm

2 stops9h 20m

$259

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 1/5

3:01 pm-9:37 pm

1 stop5h 36m

Knoxville McGhee Tyson

Mon 1/19

8:30 am-8:21 am

1 stop24h 51m

$261

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 1/6

11:50 am-5:16 pm

1 stop4h 26m

Knoxville McGhee Tyson

Wed 1/7

6:10 pm-11:30 pm

1 stop6h 20m

$277

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Sat 1/31

4:10 pm-11:44 pm

1 stop6h 34m

Knoxville McGhee Tyson

Wed 2/4

4:55 pm-9:17 pm

1 stop5h 22m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $263. If you aren’t able to travel during the month of July, then book flights to Knoxville from Louisiana during January instead. Flights to Knoxville in January, while not as cheap as those in July, still average around $278.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Louisiana to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $314. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Louisiana to Knoxville for around $403.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Louisiana to Knoxville when you can find flight prices for as low as $321. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $365.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $333 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $252 on momondo.

Can stopping save me money on Louisiana to Knoxville flights?

You could potentially save up to 71% on your flight if you consider stops on a Louisiana to Knoxville flight.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Fastest flight time

3h 24m

Direct flights

None
The fastest flight from Louisiana to Knoxville takes 3h 24m
There are no direct flights from Louisiana to Knoxville. There are no popular flight routes from Louisiana to Knoxville.
Search flight deals

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $198Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
DeltaPriceFrom $244Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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