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Cheap flights from Louisiana to Knoxville from $129

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:00 am - 6:38 pm
LFT
-
TYS
6h 38m
1 stop
Delta Logo
5:30 am - 10:33 am
TYS
-
LFT
6h 03m
1 stop
$261Delta
Tue, Nov 24 - Sat, Nov 28
Multiple Airlines Logo
12:36 pm - 10:44 pm
MSY
-
TYS
9h 08m
1 stop
Multiple Airlines Logo
6:29 pm - 11:51 am
TYS
-
MSY
18h 22m
1 stop
$266Multiple Airlines
Fri, Aug 7 - Mon, Aug 10
American Airlines Logo
6:53 am - 12:34 pm
MSY
-
TYS
4h 41m
1 stop
American Airlines Logo
8:05 pm - 11:59 pm
TYS
-
MSY
4h 54m
1 stop
$277American Airlines
Tue, Jul 21 - Sat, Jul 25
Multiple Airlines Logo
12:36 pm - 5:36 pm
MSY
-
TYS
28h 00m
1 stop
Multiple Airlines Logo
3:56 pm - 11:51 am
TYS
-
MSY
20h 55m
1 stop
$278Multiple Airlines
Wed, Aug 5 - Sun, Aug 9
Southwest Logo
11:55 am - 8:25 pm
MSY
-
TYS
7h 30m
2 stops
Southwest Logo
8:05 am - 12:05 pm
TYS
-
MSY
5h 00m
1 stop
$282Southwest
Wed, Jul 29 - Wed, Aug 5
Multiple Airlines Logo
12:36 pm - 10:44 pm
MSY
-
TYS
9h 08m
1 stop
Multiple Airlines Logo
6:29 pm - 1:29 pm
TYS
-
MSY
20h 00m
2 stops
$284Multiple Airlines
Fri, Aug 7 - Mon, Aug 10
Southwest Logo
11:55 am - 8:25 pm
MSY
-
TYS
7h 30m
2 stops
Southwest Logo
1:55 pm - 10:00 pm
TYS
-
MSY
9h 05m
2 stops
$287Southwest
Wed, Jul 29 - Wed, Aug 5
American Airlines Logo
6:00 am - 12:56 pm
BTR
-
TYS
5h 56m
1 stop
American Airlines Logo
12:52 pm - 5:55 pm
TYS
-
BTR
6h 03m
1 stop
$291American Airlines
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
4:09 pm - 11:12 pm
BTR
-
TYS
6h 03m
1 stop
United Airlines Logo
7:15 am - 11:13 am
TYS
-
BTR
4h 58m
1 stop
$371United Airlines
Sat, Aug 8 - Wed, Aug 12
United Airlines Logo
3:35 pm - 11:12 pm
SHV
-
TYS
6h 37m
1 stop
United Airlines Logo
2:21 pm - 7:29 pm
TYS
-
SHV
6h 08m
1 stop
$375United Airlines
Sat, Aug 8 - Wed, Aug 12

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Delta flights from Louisiana to Knoxville

Our best Delta deals on Louisiana to Knoxville flight tickets
Delta
Nov 24
LFT11:00 amLafayette Regional
6h 38m
1 stop
TYS6:38 pmKnoxville McGhee Tyson
Nov 28
TYS5:30 amKnoxville McGhee Tyson
6h 03m
1 stop
LFT10:33 amLafayette Regional
$261
Delta
Aug 20
LFT5:10 pmLafayette Regional
3h 50m
1 stop
TYS10:00 pmKnoxville McGhee Tyson
Aug 25
TYS4:38 pmKnoxville McGhee Tyson
6h 03m
1 stop
LFT9:41 pmLafayette Regional
$285
Delta
Oct 13
SHV6:00 amShreveport
6h 40m
1 stop
TYS1:40 pmKnoxville McGhee Tyson
Oct 17
TYS7:25 amKnoxville McGhee Tyson
6h 43m
1 stop
SHV1:08 pmShreveport
$295

United Airlines flights from Louisiana to Knoxville

Our best United Airlines deals on Louisiana to Knoxville flight tickets
United Airlines
Aug 2
MSY5:35 pmNew Orleans Louis Armstrong
4h 37m
1 stop
TYS11:12 pmKnoxville McGhee Tyson
Aug 4
TYS5:45 pmKnoxville McGhee Tyson
6h 01m
1 stop
MSY10:46 pmNew Orleans Louis Armstrong
$317
United Airlines
Aug 8
MSY3:48 pmNew Orleans Louis Armstrong
6h 24m
1 stop
TYS11:12 pmKnoxville McGhee Tyson
Aug 12
TYS7:15 amKnoxville McGhee Tyson
4h 51m
1 stop
MSY11:06 amNew Orleans Louis Armstrong
$357
United Airlines
Aug 17
MSY12:03 pmNew Orleans Louis Armstrong
5h 14m
1 stop
TYS6:17 pmKnoxville McGhee Tyson
Aug 19
TYS2:21 pmKnoxville McGhee Tyson
6h 42m
1 stop
MSY8:03 pmNew Orleans Louis Armstrong
$370

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 11/24

11:00 am-6:38 pm

1 stop6h 38m

Knoxville McGhee Tyson

Sat 11/28

5:30 am-10:33 am

1 stop6h 03m

$261

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 8/7

12:36 pm-10:44 pm

1 stop9h 08m

Knoxville McGhee Tyson

Mon 8/10

6:29 pm-11:51 am

1 stop18h 22m

$266
Quickest round-trip

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 7/21

6:53 am-12:34 pm

1 stop4h 41m

Knoxville McGhee Tyson

Sat 7/25

8:05 pm-11:59 pm

1 stop4h 54m

$277

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 8/5

12:36 pm-5:36 pm

1 stop28h 00m

Knoxville McGhee Tyson

Sun 8/9

3:56 pm-11:51 am

1 stop20h 55m

$278

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 7/29

11:55 am-8:25 pm

2 stops7h 30m

Knoxville McGhee Tyson

Wed 8/5

8:05 am-12:05 pm

1 stop5h 00m

$282

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 8/7

12:36 pm-10:44 pm

1 stop9h 08m

Knoxville McGhee Tyson

Mon 8/10

6:29 pm-1:29 pm

2 stops20h 00m

$284

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 7/29

11:55 am-8:25 pm

2 stops7h 30m

Knoxville McGhee Tyson

Wed 8/5

1:55 pm-10:00 pm

2 stops9h 05m

$287

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 9/1

6:00 am-12:56 pm

1 stop5h 56m

Knoxville McGhee Tyson

Sat 9/5

12:52 pm-5:55 pm

1 stop6h 03m

$291

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Sat 8/8

4:09 pm-11:12 pm

1 stop6h 03m

Knoxville McGhee Tyson

Wed 8/12

7:15 am-11:13 am

1 stop4h 58m

$371

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Sat 8/8

3:35 pm-11:12 pm

1 stop6h 37m

Knoxville McGhee Tyson

Wed 8/12

2:21 pm-7:29 pm

1 stop6h 08m

$375

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $218. If you aren’t able to travel during the month of November, then book flights to Knoxville from Louisiana during February instead. Flights to Knoxville in February, while not as cheap as those in November, still average around $220.

How far in advance should I book a flight from Louisiana to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $429 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $269 on momondo.

Can stopping save me money on Louisiana to Knoxville flights?

You could potentially save up to 70% on your flight if you consider stops on a Louisiana to Knoxville flight.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Fastest flight time

1h 40m

Direct flights

Sat

Airports in Knoxville

1 airport
The fastest flight from Louisiana to Knoxville takes 1h 40m
Direct flights go from Louisiana to Knoxville on Saturday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From Louisiana there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Louisiana to Knoxville

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,765 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.8
8,452 reviews
Search Delta flights
SouthwestPriceFrom $294Free CancellationRating
7.9
4,246 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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