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Cheap flights from Louisiana to Knoxville from $85

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:15 am - 8:42 pm
MSY
-
TYS
14h 27m
1 stop
Multiple Airlines Logo
12:56 pm - 11:30 pm
TYS
-
MSY
11h 34m
1 stop
$203Multiple Airlines
Thu, Apr 23 - Sat, Apr 25
Multiple Airlines Logo
5:15 am - 8:42 pm
MSY
-
TYS
14h 27m
1 stop
Multiple Airlines Logo
7:30 am - 9:15 am
TYS
-
MSY
26h 45m
1 stop
$206Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
Multiple Airlines Logo
3:39 pm - 12:06 pm
MSY
-
TYS
19h 27m
1 stop
Multiple Airlines Logo
7:30 am - 9:15 am
TYS
-
MSY
26h 45m
1 stop
$217Multiple Airlines
Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
5:15 am - 8:42 pm
MSY
-
TYS
14h 27m
1 stop
Multiple Airlines Logo
9:12 pm - 6:48 pm
TYS
-
MSY
22h 36m
1 stop
$226Multiple Airlines
Thu, Apr 23 - Sun, Apr 26
Delta Logo
6:03 am - 11:09 am
BTR
-
TYS
4h 06m
1 stop
Delta Logo
7:33 pm - 10:00 pm
TYS
-
BTR
3h 27m
1 stop
$291Delta
Wed, May 13 - Wed, May 20
American Airlines Logo
6:12 pm - 11:56 pm
LFT
-
TYS
4h 44m
1 stop
American Airlines Logo
6:54 pm - 10:59 pm
TYS
-
LFT
5h 05m
1 stop
$295American Airlines
Fri, Apr 24 - Wed, Apr 29
Delta Logo
7:08 pm - 11:54 pm
BTR
-
TYS
3h 46m
1 stop
Delta Logo
4:38 pm - 9:56 pm
TYS
-
BTR
6h 18m
1 stop
$310Delta
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
10:42 am - 6:04 pm
LFT
-
TYS
6h 22m
1 stop
American Airlines Logo
1:20 pm - 5:42 pm
TYS
-
LFT
5h 22m
1 stop
$339American Airlines
Sat, Apr 11 - Wed, Apr 15
United Airlines Logo
4:07 pm - 11:41 pm
SHV
-
TYS
6h 34m
1 stop
United Airlines Logo
11:40 am - 3:25 pm
TYS
-
SHV
4h 45m
1 stop
$371United Airlines
Sat, Apr 25 - Sat, May 2
Allegiant Air Logo
2:52 pm - 10:56 am
SHV
-
TYS
19h 04m
1 stop
Allegiant Air Logo
10:03 pm - 9:06 am
TYS
-
SHV
36h 03m
2 stops
$461Allegiant Air
Fri, May 22 - Fri, May 29

Southwest flights from Louisiana to Knoxville

Our best Southwest deals on Louisiana to Knoxville flight tickets
Southwest
May 2
MSY8:45 amNew Orleans Louis Armstrong
8h 45m
2 stops
TYS6:30 pmKnoxville McGhee Tyson
May 5
TYS2:55 pmKnoxville McGhee Tyson
5h 15m
1 stop
MSY7:10 pmNew Orleans Louis Armstrong
$302
Southwest
Apr 21
MSY6:45 amNew Orleans Louis Armstrong
6h 35m
2 stops
TYS2:20 pmKnoxville McGhee Tyson
Apr 25
TYS6:40 amKnoxville McGhee Tyson
8h 00m
2 stops
MSY1:40 pmNew Orleans Louis Armstrong
$307
Southwest
May 2
MSY5:50 amNew Orleans Louis Armstrong
12h 45m
1 stop
TYS7:35 pmKnoxville McGhee Tyson
May 3
TYS7:35 pmKnoxville McGhee Tyson
5h 30m
1 stop
MSY12:05 amNew Orleans Louis Armstrong
$332

Delta flights from Louisiana to Knoxville

Our best Delta deals on Louisiana to Knoxville flight tickets
Delta
May 13
BTR6:03 amBaton Rouge Ryan
4h 06m
1 stop
TYS11:09 amKnoxville McGhee Tyson
May 20
TYS7:33 pmKnoxville McGhee Tyson
3h 27m
1 stop
BTR10:00 pmBaton Rouge Ryan
$291
Delta
Apr 21
BTR7:08 pmBaton Rouge Ryan
3h 46m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Apr 28
TYS4:38 pmKnoxville McGhee Tyson
6h 18m
1 stop
BTR9:56 pmBaton Rouge Ryan
$310
Delta
Apr 21
BTR7:08 pmBaton Rouge Ryan
3h 46m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Apr 28
TYS5:54 pmKnoxville McGhee Tyson
5h 02m
1 stop
BTR9:56 pmBaton Rouge Ryan
$329

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 4/23

5:15 am-8:42 pm

1 stop14h 27m

Knoxville McGhee Tyson

Sat 4/25

12:56 pm-11:30 pm

1 stop11h 34m

$203

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 4/23

5:15 am-8:42 pm

1 stop14h 27m

Knoxville McGhee Tyson

Mon 4/27

7:30 am-9:15 am

1 stop26h 45m

$206

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 4/17

3:39 pm-12:06 pm

1 stop19h 27m

Knoxville McGhee Tyson

Mon 4/20

7:30 am-9:15 am

1 stop26h 45m

$217

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 4/23

5:15 am-8:42 pm

1 stop14h 27m

Knoxville McGhee Tyson

Sun 4/26

9:12 pm-6:48 pm

1 stop22h 36m

$226
Quickest round-trip

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Wed 5/13

6:03 am-11:09 am

1 stop4h 06m

Knoxville McGhee Tyson

Wed 5/20

7:33 pm-10:00 pm

1 stop3h 27m

$291

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 4/24

6:12 pm-11:56 pm

1 stop4h 44m

Knoxville McGhee Tyson

Wed 4/29

6:54 pm-10:59 pm

1 stop5h 05m

$295

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 4/21

7:08 pm-11:54 pm

1 stop3h 46m

Knoxville McGhee Tyson

Tue 4/28

4:38 pm-9:56 pm

1 stop6h 18m

$310

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

10:42 am-6:04 pm

1 stop6h 22m

Knoxville McGhee Tyson

Wed 4/15

1:20 pm-5:42 pm

1 stop5h 22m

$339

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Sat 4/25

4:07 pm-11:41 pm

1 stop6h 34m

Knoxville McGhee Tyson

Sat 5/2

11:40 am-3:25 pm

1 stop4h 45m

$371

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Fri 5/22

2:52 pm-10:56 am

1 stop19h 04m

Knoxville McGhee Tyson

Fri 5/29

10:03 pm-9:06 am

2 stops36h 03m

$461

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $263. If you aren’t able to travel during the month of July, then book flights to Knoxville from Louisiana during September instead. Flights to Knoxville in September, while not as cheap as those in July, still average around $281.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $268 on momondo.

Can stopping save me money on Louisiana to Knoxville flights?

You could potentially save up to 71% on your flight if you consider stops on a Louisiana to Knoxville flight.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Fastest flight time

3h 20m

Direct flights

None
The fastest flight from Louisiana to Knoxville takes 3h 20m
There are no direct flights from Louisiana to Knoxville. There are no popular flight routes from Louisiana to Knoxville.
Search flight deals

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $224Free CancellationRating
7.1
11,543 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,364 reviews
Search Delta flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,332 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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