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Cheap flights from Louisiana to Knoxville from $137

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisiana to Knoxville departing on 4/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:30 pm - 1:15 pm
MSY
-
TYS
20h 45m
1 stop
Multiple Airlines Logo
8:58 am - 8:19 am
TYS
-
MSY
24h 21m
1 stop
$188Multiple Airlines
Tue, Mar 24 - Mon, Mar 30
Multiple Airlines Logo
7:10 pm - 8:10 am
MSY
-
TYS
12h 00m
1 stop
Multiple Airlines Logo
9:00 am - 8:19 am
TYS
-
MSY
24h 19m
1 stop
$194Multiple Airlines
Thu, Apr 2 - Mon, Apr 6
Multiple Airlines Logo
7:10 pm - 11:39 pm
MSY
-
TYS
27h 29m
1 stop
Multiple Airlines Logo
9:00 am - 8:19 am
TYS
-
MSY
24h 19m
1 stop
$196Multiple Airlines
Wed, Apr 1 - Mon, Apr 6
American Airlines Logo
4:51 pm - 10:48 pm
SHV
-
TYS
4h 57m
1 stop
American Airlines Logo
4:29 pm - 9:56 pm
TYS
-
SHV
6h 27m
1 stop
$251American Airlines
Tue, Mar 10 - Tue, Mar 17
Delta Logo
6:07 am - 11:17 am
BTR
-
TYS
4h 10m
1 stop
Delta Logo
5:40 am - 9:45 am
TYS
-
BTR
5h 05m
1 stop
$269Delta
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
5:57 pm - 12:28 am
BTR
-
TYS
5h 31m
1 stop
American Airlines Logo
5:40 am - 9:54 am
TYS
-
BTR
5h 14m
1 stop
$274American Airlines
Sat, Feb 28 - Wed, Mar 11
Delta Logo
6:00 am - 11:08 am
SHV
-
TYS
4h 08m
1 stop
Delta Logo
2:37 pm - 7:59 pm
TYS
-
SHV
6h 22m
1 stop
$279Delta
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
4:06 pm - 11:41 pm
LFT
-
TYS
6h 35m
1 stop
United Airlines Logo
7:05 am - 11:16 am
TYS
-
LFT
5h 11m
1 stop
$310United Airlines
Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
12:14 pm - 7:55 pm
BTR
-
TYS
6h 41m
1 stop
United Airlines Logo
7:05 am - 11:27 am
TYS
-
BTR
5h 22m
1 stop
$349United Airlines
Tue, Feb 24 - Sat, Feb 28
Allegiant Air Logo
2:52 pm - 10:56 am
SHV
-
TYS
19h 04m
1 stop
Allegiant Air Logo
10:03 pm - 9:06 am
TYS
-
SHV
36h 03m
2 stops
$379Allegiant Air
Fri, May 22 - Fri, May 29

United Airlines flights from Louisiana to Knoxville

Our best United Airlines deals on Louisiana to Knoxville flight tickets
United Airlines
Apr 21
LFT4:06 pmLafayette Regional
6h 35m
1 stop
TYS11:41 pmKnoxville McGhee Tyson
Apr 28
TYS7:05 amKnoxville McGhee Tyson
5h 11m
1 stop
LFT11:16 amLafayette Regional
$310
United Airlines
Feb 26
MSY8:00 amNew Orleans Louis Armstrong
6h 15m
1 stop
TYS3:15 pmKnoxville McGhee Tyson
Mar 3
TYS2:21 pmKnoxville McGhee Tyson
6h 28m
1 stop
MSY7:49 pmNew Orleans Louis Armstrong
$347
United Airlines
Feb 24
BTR12:14 pmBaton Rouge Ryan
6h 41m
1 stop
TYS7:55 pmKnoxville McGhee Tyson
Feb 28
TYS7:05 amKnoxville McGhee Tyson
5h 22m
1 stop
BTR11:27 amBaton Rouge Ryan
$349

Southwest flights from Louisiana to Knoxville

Our best Southwest deals on Louisiana to Knoxville flight tickets
Southwest
Apr 18
MSY9:45 amNew Orleans Louis Armstrong
4h 35m
1 stop
TYS3:20 pmKnoxville McGhee Tyson
Apr 21
TYS7:05 amKnoxville McGhee Tyson
7h 25m
2 stops
MSY1:30 pmNew Orleans Louis Armstrong
$282
Southwest
Apr 18
MSY8:30 amNew Orleans Louis Armstrong
9h 00m
2 stops
TYS6:30 pmKnoxville McGhee Tyson
Apr 21
TYS2:55 pmKnoxville McGhee Tyson
7h 55m
2 stops
MSY9:50 pmNew Orleans Louis Armstrong
$287
Southwest
Mar 25
MSY1:35 pmNew Orleans Louis Armstrong
5h 30m
1 stop
TYS8:05 pmKnoxville McGhee Tyson
Mar 26
TYS7:25 pmKnoxville McGhee Tyson
5h 45m
1 stop
MSY12:10 amNew Orleans Louis Armstrong
$289

momondo Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 3/24

3:30 pm-1:15 pm

1 stop20h 45m

Knoxville McGhee Tyson

Mon 3/30

8:58 am-8:19 am

1 stop24h 21m

$188

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 4/2

7:10 pm-8:10 am

1 stop12h 00m

Knoxville McGhee Tyson

Mon 4/6

9:00 am-8:19 am

1 stop24h 19m

$194

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 4/1

7:10 pm-11:39 pm

1 stop27h 29m

Knoxville McGhee Tyson

Mon 4/6

9:00 am-8:19 am

1 stop24h 19m

$196

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Tue 3/10

4:51 pm-10:48 pm

1 stop4h 57m

Knoxville McGhee Tyson

Tue 3/17

4:29 pm-9:56 pm

1 stop6h 27m

$251

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 3/10

6:07 am-11:17 am

1 stop4h 10m

Knoxville McGhee Tyson

Tue 3/17

5:40 am-9:45 am

1 stop5h 05m

$269

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Sat 2/28

5:57 pm-12:28 am

1 stop5h 31m

Knoxville McGhee Tyson

Wed 3/11

5:40 am-9:54 am

1 stop5h 14m

$274

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Tue 2/24

6:00 am-11:08 am

1 stop4h 08m

Knoxville McGhee Tyson

Sat 2/28

2:37 pm-7:59 pm

1 stop6h 22m

$279

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 4/21

4:06 pm-11:41 pm

1 stop6h 35m

Knoxville McGhee Tyson

Tue 4/28

7:05 am-11:16 am

1 stop5h 11m

$310

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 2/24

12:14 pm-7:55 pm

1 stop6h 41m

Knoxville McGhee Tyson

Sat 2/28

7:05 am-11:27 am

1 stop5h 22m

$349

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Fri 5/22

2:52 pm-10:56 am

1 stop19h 04m

Knoxville McGhee Tyson

Fri 5/29

10:03 pm-9:06 am

2 stops36h 03m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Louisiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Louisiana, with most prices found around $263. If you aren’t able to travel during the month of July, then book flights to Knoxville from Louisiana during September instead. Flights to Knoxville in September, while not as cheap as those in July, still average around $278.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Louisiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $360 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Louisiana for as low as $252 on momondo.

Can stopping save me money on Louisiana to Knoxville flights?

You could potentially save up to 71% on your flight if you consider stops on a Louisiana to Knoxville flight.

Cheap Louisiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisiana to Knoxville

Fastest flight time

3h 35m

Direct flights

None
The fastest flight from Louisiana to Knoxville takes 3h 35m
There are no direct flights from Louisiana to Knoxville. There are no popular flight routes from Louisiana to Knoxville.
Search flight deals

  • When did momondo last update prices for flights from Louisiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Louisiana to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Louisiana to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisiana to Knoxville

Compare and see reviews for airlines that fly from Louisiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $108Free CancellationRating
7.9
8,186 reviews
Search Delta flights
United AirlinesPriceFrom $198Free CancellationRating
7.4
9,283 reviews
Search United Airlines flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Alcoa
Crossville
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Louisiana to Knoxville?

Finding the right flight to Knoxville from Louisiana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Louisiana to Knoxville with flexible booking policies on momondo?

All flight searches from Louisiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisiana to Knoxville?

Once you have performed a search for Louisiana to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisiana to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisiana to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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