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Cheap flights from Iowa to Key West from $219

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Key West departing on 7/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Iowa to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:20 pm - 10:24 am
DSM
-
EYW
18h 04m
1 stop
Multiple Airlines Logo
2:44 pm - 9:43 pm
EYW
-
DSM
7h 59m
1 stop
$266Multiple Airlines
Sat, Jul 4 - Sat, Jul 11
Multiple Airlines Logo
3:20 pm - 10:24 am
DSM
-
EYW
18h 04m
1 stop
Multiple Airlines Logo
4:41 pm - 10:15 pm
EYW
-
DSM
6h 34m
1 stop
$269Multiple Airlines
Sat, Jul 4 - Fri, Jul 10
Allegiant Air Logo
4:59 pm - 12:48 pm
DSM
-
EYW
18h 49m
1 stop
Allegiant Air Logo
4:41 pm - 10:15 pm
EYW
-
DSM
6h 34m
1 stop
$275Allegiant Air
Sat, Jul 4 - Fri, Jul 10
American Airlines Logo
8:45 am - 3:42 pm
DSM
-
EYW
5h 57m
1 stop
American Airlines Logo
1:01 pm - 7:30 pm
EYW
-
DSM
7h 29m
1 stop
$289American Airlines
Sat, Jul 4 - Wed, Jul 8
Multiple Airlines Logo
4:59 pm - 12:48 pm
DSM
-
EYW
18h 49m
1 stop
Multiple Airlines Logo
11:46 am - 9:32 pm
EYW
-
DSM
34h 46m
2 stops
$290Multiple Airlines
Sat, Jul 4 - Wed, Jul 8
Allegiant Air Logo
4:07 pm - 1:58 pm
DSM
-
EYW
20h 51m
1 stop
Allegiant Air Logo
2:48 pm - 10:52 pm
EYW
-
DSM
9h 04m
1 stop
$294Allegiant Air
Fri, Jun 19 - Sat, Jun 27
Delta Logo
12:20 pm - 7:50 pm
OMA
-
EYW
6h 30m
1 stop
Delta Logo
7:40 am - 12:45 pm
EYW
-
OMA
6h 05m
1 stop
$323Delta
Sat, Sep 19 - Wed, Sep 23
Delta Logo
12:10 pm - 7:54 pm
OMA
-
EYW
6h 44m
1 stop
Delta Logo
11:48 am - 5:20 pm
EYW
-
OMA
6h 32m
1 stop
$326Delta
Sat, Aug 8 - Thu, Aug 13
American Airlines Logo
2:03 pm - 9:47 pm
OMA
-
EYW
6h 44m
1 stop
American Airlines Logo
4:53 pm - 11:26 pm
EYW
-
OMA
7h 33m
1 stop
$329American Airlines
Thu, Nov 26 - Tue, Dec 1
United Airlines Logo
8:07 am - 3:19 pm
CID
-
EYW
6h 12m
1 stop
United Airlines Logo
4:00 pm - 8:58 pm
EYW
-
CID
5h 58m
1 stop
$346United Airlines
Thu, Jul 9 - Wed, Aug 5

American Airlines flights from Iowa to Key West

Our best American Airlines deals on Iowa to Key West flight tickets
American Airlines
Jul 4
DSM8:45 amDes Moines
5h 57m
1 stop
EYW3:42 pmKey West
Jul 8
EYW1:01 pmKey West
7h 29m
1 stop
DSM7:30 pmDes Moines
$289
American Airlines
Nov 26
OMA2:03 pmOmaha Eppley Airfield
6h 44m
1 stop
EYW9:47 pmKey West
Dec 1
EYW4:53 pmKey West
7h 33m
1 stop
OMA11:26 pmOmaha Eppley Airfield
$329
American Airlines
Jun 27
MLI6:00 amMoline Quad-City
8h 41m
1 stop
EYW3:41 pmKey West
Jul 1
EYW1:39 pmKey West
11h 32m
2 stops
MLI12:11 amMoline Quad-City
$334

Delta flights from Iowa to Key West

Our best Delta deals on Iowa to Key West flight tickets
Delta
Jul 3
DSM11:42 amDes Moines
7h 11m
1 stop
EYW7:53 pmKey West
Jul 8
EYW6:18 pmKey West
5h 11m
1 stop
DSM10:29 pmDes Moines
$309
Delta
Sep 19
OMA12:20 pmOmaha Eppley Airfield
6h 30m
1 stop
EYW7:50 pmKey West
Sep 23
EYW7:40 amKey West
6h 05m
1 stop
OMA12:45 pmOmaha Eppley Airfield
$323
Delta
Aug 8
OMA12:10 pmOmaha Eppley Airfield
6h 44m
1 stop
EYW7:54 pmKey West
Aug 13
EYW11:48 amKey West
6h 32m
1 stop
OMA5:20 pmOmaha Eppley Airfield
$326

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 3, 2026.
Use the filters below to find and compare flights from Iowa to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 7/4

3:20 pm-10:24 am

1 stop18h 04m

Key West

Sat 7/11

2:44 pm-9:43 pm

1 stop7h 59m

$266

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 7/4

3:20 pm-10:24 am

1 stop18h 04m

Key West

Fri 7/10

4:41 pm-10:15 pm

1 stop6h 34m

$269

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 7/4

4:59 pm-12:48 pm

1 stop18h 49m

Key West

Fri 7/10

4:41 pm-10:15 pm

1 stop6h 34m

$275

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 7/4

8:45 am-3:42 pm

1 stop5h 57m

Key West

Wed 7/8

1:01 pm-7:30 pm

1 stop7h 29m

$289

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 7/4

4:59 pm-12:48 pm

1 stop18h 49m

Key West

Wed 7/8

11:46 am-9:32 pm

2 stops34h 46m

$290

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Fri 6/19

4:07 pm-1:58 pm

1 stop20h 51m

Key West

Sat 6/27

2:48 pm-10:52 pm

1 stop9h 04m

$294

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Sat 9/19

12:20 pm-7:50 pm

1 stop6h 30m

Key West

Wed 9/23

7:40 am-12:45 pm

1 stop6h 05m

$323

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Sat 8/8

12:10 pm-7:54 pm

1 stop6h 44m

Key West

Thu 8/13

11:48 am-5:20 pm

1 stop6h 32m

$326

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Thu 11/26

2:03 pm-9:47 pm

1 stop6h 44m

Key West

Tue 12/1

4:53 pm-11:26 pm

1 stop7h 33m

$329
Quickest round-trip

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Thu 7/9

8:07 am-3:19 pm

1 stop6h 12m

Key West

Wed 8/5

4:00 pm-8:58 pm

1 stop5h 58m

$346

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Iowa to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Iowa to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $76. If you are unable to visit Key West during the month of July, then departing from Iowa during the month November is also very affordable. Most momondo users find prices during this month for around $95.

Can stopping save me money on Iowa to Key West flights?

You could potentially save up to 16% on your flight if you consider stops on a Iowa to Key West flight.

Cheap Iowa to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Key West

Fastest flight time

5h 08m

Direct flights

None
The fastest flight from Iowa to Key West takes 5h 08m
There are no direct flights from Iowa to Key West. There are no popular flight routes from Iowa to Key West.
Search flight deals

Frequently asked questions about flying from Iowa to Key West

  • When did momondo last update prices for flights from Iowa to Key West Airport?

    Prices for flights from Iowa to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Iowa to Key West Airport?

  • How old do you have to be to fly from Iowa to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Key West

Compare and see reviews for airlines that fly from Iowa to Key West with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $76Free CancellationRating
7.3
706 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $230Free CancellationRating
7.4
9,771 reviews
Search United Airlines flights
DeltaPriceFrom $243Free CancellationRating
7.9
8,398 reviews
Search Delta flights
American AirlinesPriceFrom $268Free CancellationRating
7.1
11,641 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Key West?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Key West from Iowa.

Can I find flights from Iowa to Key West with flexible booking policies on momondo?

Flights from Iowa to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Key West?

momondo provides multiple filters to help you find the best flight to Key West from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Key West trip

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