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Cheap flights from Iowa to Charleston from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Charleston departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Iowa to Charleston

Cheap round-trip flights

American Airlines Logo
6:32 pm - 12:15 amMLI-CHS
4h 43m1 stop
American Airlines Logo
7:45 pm - 11:39 pmCHS-MLI
4h 54m1 stop
$249American Airlines
Find Deal
Wed, Oct 15 - Sat, Oct 18
Delta Logo
5:57 am - 1:49 pmCID-CHS
6h 52m1 stop
Delta Logo
6:59 pm - 10:43 pmCHS-CID
4h 44m1 stop
$249Delta
Find Deal
Sat, Sep 13 - Mon, Sep 15
Delta Logo
4:59 pm - 11:51 pmMLI-CHS
5h 52m1 stop
Delta Logo
5:35 pm - 10:48 pmCHS-MLI
6h 13m1 stop
$254Delta
Find Deal
Fri, Sep 5 - Tue, Sep 9
Delta Logo
12:20 pm - 11:48 pmCID-CHS
10h 28m2 stops
Delta Logo
4:44 pm - 10:43 pmCHS-CID
6h 59m1 stop
$254Delta
Find Deal
Sat, Sep 13 - Tue, Sep 16
United Airlines Logo
11:35 am - 7:08 pmDSM-CHS
6h 33m1 stop
United Airlines Logo
4:34 pm - 9:45 pmCHS-DSM
6h 11m1 stop
$291United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
Southwest Logo
3:50 pm - 9:15 pmOMA-CHS
4h 25m1 stop
Southwest Logo
10:55 am - 4:20 pmCHS-OMA
6h 25m1 stop
$291Southwest
Find Deal
Wed, Oct 1 - Sat, Oct 4
United Airlines Logo
11:35 am - 11:30 pmDSM-CHS
10h 55m2 stops
United Airlines Logo
4:12 pm - 11:41 pmCHS-DSM
8h 29m1 stop
$296United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
Southwest Logo
4:50 pm - 10:55 pmOMA-CHS
5h 05m1 stop
Southwest Logo
6:00 am - 2:40 pmCHS-OMA
9h 40m2 stops
$307Southwest
Find Deal
Fri, Nov 7 - Tue, Nov 11
Logo
8:25 am - 5:07 pmDSM-CHS
7h 42m1 stop
Logo
12:08 pm - 1:32 pmCHS-DSM
26h 24m2 stops
$310
Find Deal
Fri, Sep 5 - Sun, Sep 7
Logo
5:49 pm - 9:05 amDSM-CHS
14h 16m2 stops
Logo
12:08 pm - 2:40 pmCHS-DSM
27h 32m3 stops
$349
Find Deal
Thu, Sep 11 - Sun, Sep 14

American Airlines flights from Iowa to Charleston

Our best American Airlines deals on Iowa to Charleston flight tickets
American Airlines
Oct 15
MLI6:32 pmMoline Quad-City
4h 43m
1 stop
CHS12:15 amCharleston
Oct 18
CHS7:45 pmCharleston
4h 54m
1 stop
MLI11:39 pmMoline Quad-City
$249
Find similar
American Airlines
Sep 3
CID9:30 amCedar Rapids
5h 11m
1 stop
CHS3:41 pmCharleston
Sep 7
CHS8:17 pmCharleston
4h 42m
1 stop
CID11:59 pmCedar Rapids
$259
Find similar
American Airlines
Sep 3
CID5:09 amCedar Rapids
10h 38m
2 stops
CHS4:47 pmCharleston
Sep 7
CHS8:17 pmCharleston
4h 42m
1 stop
CID11:59 pmCedar Rapids
$264
Find similar

Delta flights from Iowa to Charleston

Our best Delta deals on Iowa to Charleston flight tickets
Delta
Sep 13
CID5:57 amCedar Rapids
6h 52m
1 stop
CHS1:49 pmCharleston
Sep 15
CHS6:59 pmCharleston
4h 44m
1 stop
CID10:43 pmCedar Rapids
$249
Find similar
Delta
Sep 5
MLI4:59 pmMoline Quad-City
5h 52m
1 stop
CHS11:51 pmCharleston
Sep 9
CHS5:35 pmCharleston
6h 13m
1 stop
MLI10:48 pmMoline Quad-City
$254
Find similar
Delta
Sep 3
MLI4:59 pmMoline Quad-City
5h 52m
1 stop
CHS11:51 pmCharleston
Sep 6
CHS5:37 pmCharleston
6h 11m
1 stop
MLI10:48 pmMoline Quad-City
$259
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Iowa to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 10/15

6:32 pm-12:15 am

1 stop4h 43m

Charleston

Sat 10/18

7:45 pm-11:39 pm

1 stop4h 54m

$249

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 9/13

5:57 am-1:49 pm

1 stop6h 52m

Charleston

Mon 9/15

6:59 pm-10:43 pm

1 stop4h 44m

$249

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 9/5

4:59 pm-11:51 pm

1 stop5h 52m

Charleston

Tue 9/9

5:35 pm-10:48 pm

1 stop6h 13m

$254

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 9/13

12:20 pm-11:48 pm

2 stops10h 28m

Charleston

Tue 9/16

4:44 pm-10:43 pm

1 stop6h 59m

$254

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Sat 9/13

11:35 am-7:08 pm

1 stop6h 33m

Charleston

Sat 9/20

4:34 pm-9:45 pm

1 stop6h 11m

$291

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Wed 10/1

3:50 pm-9:15 pm

1 stop4h 25m

Charleston

Sat 10/4

10:55 am-4:20 pm

1 stop6h 25m

$291

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Sat 9/13

11:35 am-11:30 pm

2 stops10h 55m

Charleston

Sat 9/20

4:12 pm-11:41 pm

1 stop8h 29m

$296

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Fri 11/7

4:50 pm-10:55 pm

1 stop5h 05m

Charleston

Tue 11/11

6:00 am-2:40 pm

2 stops9h 40m

$307

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Fri 9/5

8:25 am-5:07 pm

1 stop7h 42m

Charleston

Sun 9/7

12:08 pm-1:32 pm

2 stops26h 24m

$310

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Thu 9/11

5:49 pm-9:05 am

2 stops14h 16m

Charleston

Sun 9/14

12:08 pm-2:40 pm

3 stops27h 32m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Iowa to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Iowa is in October. Flight prices, which tend to average around $331, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Charleston, with average flight prices from Iowa averaging around $334.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Iowa to Charleston is on a Monday. Travelers who choose to depart for Charleston on a Monday will often find tickets for as low as $379. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $508.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the afternoon when flights can be purchased for as low as $386. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $405 per ticket.

How far in advance should I book a flight to Charleston?

You are more likely to see cheaper flights to Charleston from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Iowa for as low as $329 on momondo.

Can stopping save me money on Iowa to Charleston flights?

You could potentially save up to 52% on your flight if you consider stops on a Iowa to Charleston flight.

Cheap Iowa to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Charleston

Direct flights

None
There are no direct flights from Iowa to Charleston. There are no popular flight routes from Iowa to Charleston.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Charleston Airport?

    Prices for flights from Iowa to Charleston Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Iowa to Charleston Airport?

  • How old do you have to be to fly from Iowa to Charleston Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The necessary travel and health documents for your Charleston Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Charleston

Compare and see reviews for airlines that fly from Iowa to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $237Free CancellationRating
7.9
7,982 reviews
Search Delta flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
8,928 reviews
Search United Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Walterboro
Goose Creek
Santee
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Charleston?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to Charleston. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to Charleston with flexible booking policies on momondo?

All flight searches from Iowa to Charleston on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Charleston?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Charleston from Iowa.

I’m not ready to book a flight from Iowa to Charleston right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to Charleston now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Charleston and let you know when they change.

An easier way to manage your Charleston trip

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