What is the cheapest airline that flies from Iowa to Buffalo?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Iowa to Buffalo

What airlines fly to Buffalo?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Buffalo from Iowa according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 3 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Buffalo?

On average, it takes 4h 19m to fly from Iowa to Buffalo if you fly out of Cedar Rapids (the most popular airport in Iowa) and into Buffalo (the most popular airport in Buffalo). If you’re flying out of Des Moines and into Buffalo, then the flight time is around 4h 30m.

When did momondo last update prices for flights from Iowa to Buffalo Airport?

Prices for flights from Iowa to Buffalo Airport refresh daily.

How many operators does momondo search for flights from Iowa to Buffalo Airport?

There are 4 operators available for flights from Iowa to Buffalo Airport as of November 2025.

How old do you have to be to fly from Iowa to Buffalo Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$140 Cheap Flights from Iowa to Buffalo in 2025/26

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Find the cheapest flights from Iowa to Buffalo

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:08 pm - 11:59 pmMLI-BUF

5h 51m1 stop

12:10 pm - 4:19 pmBUF-MLI

5h 09m1 stop

$249Delta

Find Deal

Sat, Dec 6 - Sat, Dec 13

5:08 pm - 11:59 pmMLI-BUF

5h 51m1 stop

6:12 am - 4:19 pmBUF-MLI

11h 07m2 stops

$254Delta

Find Deal

Sat, Dec 6 - Sat, Dec 13

5:12 pm - 11:50 pmMLI-BUF

5h 38m1 stop

12:05 pm - 4:28 pmBUF-MLI

5h 23m1 stop

$279Delta

Find Deal

Sun, Nov 23 - Thu, Nov 27

9:52 am - 3:56 pmCID-BUF

5h 04m1 stop

6:10 am - 10:59 amBUF-CID

5h 49m1 stop

$309American Airlines

Find Deal

Wed, Nov 26 - Thu, Nov 27

10:15 am - 5:07 pmOMA-BUF

5h 52m1 stop

6:50 pm - 11:59 pmBUF-OMA

6h 09m1 stop

$317Delta

Find Deal

Tue, Mar 24 - Wed, Mar 25

6:00 am - 11:46 amMLI-BUF

4h 46m1 stop

6:00 am - 3:04 pmBUF-MLI

10h 04m1 stop

$319American Airlines

Find Deal

Wed, Feb 18 - Sat, Feb 21

1:10 pm - 8:28 pmCID-BUF

6h 18m1 stop

7:00 am - 11:49 amBUF-CID

5h 49m1 stop

$319United Airlines

Find Deal

Wed, Mar 25 - Sat, Mar 28

8:00 am - 6:39 pmCID-BUF

9h 39m2 stops

7:00 am - 10:35 amBUF-CID

4h 35m1 stop

$350United Airlines

Find Deal

Thu, Nov 27 - Fri, Nov 28

5:15 am - 10:30 amOMA-BUF

4h 15m1 stop

12:05 pm - 8:05 pmBUF-OMA

9h 00m1 stop

$412Southwest

Find Deal

Fri, Apr 3 - Mon, Apr 6

2:25 pm - 12:10 amOMA-BUF

8h 45m2 stops

12:05 pm - 8:05 pmBUF-OMA

9h 00m1 stop

$428Southwest

Find Deal

Fri, Apr 3 - Mon, Apr 6

Delta flights from Iowa to Buffalo

Our best Delta deals on Iowa to Buffalo flight tickets

Delta

Dec 6

MLI5:08 pmMoline Quad-City

5h 51m

1 stop

BUF11:59 pmBuffalo

Dec 13

BUF12:10 pmBuffalo

5h 09m

1 stop

MLI4:19 pmMoline Quad-City

$249

Find similar

Delta

Dec 6

MLI5:08 pmMoline Quad-City

5h 51m

1 stop

BUF11:59 pmBuffalo

Dec 13

BUF6:12 amBuffalo

11h 07m

2 stops

MLI4:19 pmMoline Quad-City

$254

Find similar

Delta

Nov 23

MLI5:12 pmMoline Quad-City

5h 38m

1 stop

BUF11:50 pmBuffalo

Nov 27

BUF12:05 pmBuffalo

5h 23m

1 stop

MLI4:28 pmMoline Quad-City

$279

Find similar

American Airlines flights from Iowa to Buffalo

Our best American Airlines deals on Iowa to Buffalo flight tickets

American Airlines

Nov 26

CID9:52 amCedar Rapids

5h 04m

1 stop

BUF3:56 pmBuffalo

Nov 27

BUF6:10 amBuffalo

5h 49m

1 stop

CID10:59 amCedar Rapids

$309

Find similar

American Airlines

Feb 18

MLI6:00 amMoline Quad-City

4h 46m

1 stop

BUF11:46 amBuffalo

Feb 21

BUF6:00 amBuffalo

10h 04m

1 stop

MLI3:04 pmMoline Quad-City

$319

Find similar

American Airlines

Feb 18

MLI2:00 pmMoline Quad-City

7h 31m

2 stops

BUF10:31 pmBuffalo

Feb 21

BUF6:00 amBuffalo

10h 04m

1 stop

MLI3:04 pmMoline Quad-City

$324

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 12/6

5:08 pm-11:59 pm

1 stop5h 51m

Buffalo

Sat 12/13

12:10 pm-4:19 pm

1 stop5h 09m

$249

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 12/6

5:08 pm-11:59 pm

1 stop5h 51m

Buffalo

Sat 12/13

6:12 am-4:19 pm

2 stops11h 07m

$254

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sun 11/23

5:12 pm-11:50 pm

1 stop5h 38m

Buffalo

Thu 11/27

12:05 pm-4:28 pm

1 stop5h 23m

$279

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Wed 11/26

9:52 am-3:56 pm

1 stop5h 04m

Buffalo

Thu 11/27

6:10 am-10:59 am

1 stop5h 49m

$309

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Tue 3/24

10:15 am-5:07 pm

1 stop5h 52m

Buffalo

Wed 3/25

6:50 pm-11:59 pm

1 stop6h 09m

$317

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Wed 2/18

6:00 am-11:46 am

1 stop4h 46m

Buffalo

Sat 2/21

6:00 am-3:04 pm

1 stop10h 04m

$319

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Wed 3/25

1:10 pm-8:28 pm

1 stop6h 18m

Buffalo

Sat 3/28

7:00 am-11:49 am

1 stop5h 49m

$319

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Thu 11/27

8:00 am-6:39 pm

2 stops9h 39m

Buffalo

Fri 11/28

7:00 am-10:35 am

1 stop4h 35m

$350

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Fri 4/3

5:15 am-10:30 am

1 stop4h 15m

Buffalo

Mon 4/6

12:05 pm-8:05 pm

1 stop9h 00m

$412

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Fri 4/3

2:25 pm-12:10 am

2 stops8h 45m

Buffalo

Mon 4/6

12:05 pm-8:05 pm

1 stop9h 00m

$428

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Tuesday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $321. Flights from Iowa to Buffalo on a Friday will generally be more expensive and average around $497. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the morning is the cheapest time of day to fly from Iowa to Buffalo when you can find flight prices for as low as $356. Flying to Buffalo in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $452 per ticket.

Cheap Iowa to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Buffalo

Direct flights	None

There are no direct flights from Iowa to Buffalo. There are no popular flight routes from Iowa to Buffalo.

Search flight deals

When did momondo last update prices for flights from Iowa to Buffalo Airport?
Prices for flights from Iowa to Buffalo Airport refresh daily.
How many operators does momondo search for flights from Iowa to Buffalo Airport?
There are 4 operators available for flights from Iowa to Buffalo Airport as of November 2025.
How old do you have to be to fly from Iowa to Buffalo Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Buffalo

Compare and see reviews for airlines that fly from Iowa to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $148	Free Cancellation	Rating 7.9 8,004 reviews	Search Delta flights
American Airlines	PriceFrom $238	Free Cancellation	Rating 7.2 11,047 reviews	Search American Airlines flights
United Airlines	PriceFrom $278	Free Cancellation	Rating 7.4 9,012 reviews	Search United Airlines flights

Batavia

Cheektowaga

Amherst

Tonawanda

Grand Island

Williamsville

Lockport

Orchard Park

West Seneca

East Aurora

Bowmansville

Eden

Angola

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Buffalo?

Finding the right flight to Buffalo from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Buffalo quick and easy, saving you time and money.

Can I find flights from Iowa to Buffalo with flexible booking policies on momondo?

Yes. All flights to Buffalo from Iowa on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Iowa to Buffalo?

momondo helps you find the best flight between Iowa and Buffalo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Iowa to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.