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Cheap flights from Indianapolis to South America from $162

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to South America departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Indianapolis to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
8:17 pm - 1:13 pmIND-CTG
16h 56m1 stop
Spirit Airlines Logo
2:21 pm - 10:38 pmCTG-IND
8h 17m1 stop
$256Spirit Airlines
Find Deal
Sat, Feb 21 - Tue, Feb 24
Spirit Airlines Logo
8:17 pm - 1:13 pmIND-CTG
16h 56m1 stop
Spirit Airlines Logo
2:21 pm - 10:38 pmCTG-IND
8h 17m1 stop
$273Spirit Airlines
Find Deal
Sat, Feb 21 - Tue, Feb 24
Multiple Airlines Logo
9:34 pm - 12:50 pmIND-BOG
15h 16m1 stop
Multiple Airlines Logo
1:45 pm - 11:43 amBOG-IND
21h 58m2 stops
$362Multiple Airlines
Find Deal
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
5:10 am - 6:10 pmIND-BOG
13h 00m1 stop
Multiple Airlines Logo
9:15 am - 10:48 pmBOG-IND
13h 33m1 stop
$371Multiple Airlines
Find Deal
Tue, Jan 20 - Mon, Jan 26
Air Canada Logo
4:35 pm - 9:50 amIND-GRU
40h 15m2 stops
Air Canada Logo
9:00 pm - 3:49 pmGRU-IND
19h 49m2 stops
$704Air Canada
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Mon, May 4 - Mon, May 18
Air Canada Logo
10:30 am - 9:05 amIND-GRU
21h 35m1 stop
Air Canada Logo
9:00 pm - 8:35 pmGRU-IND
24h 35m2 stops
$709Air Canada
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Tue, May 19 - Wed, May 27
LATAM Airlines Logo
12:27 pm - 6:55 amIND-SCL
16h 28m1 stop
LATAM Airlines Logo
11:10 pm - 10:36 amSCL-IND
13h 26m1 stop
$748LATAM Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
LATAM Airlines Logo
12:24 pm - 6:55 amIND-SCL
16h 31m1 stop
LATAM Airlines Logo
11:30 pm - 12:12 pmSCL-IND
14h 42m1 stop
$751LATAM Airlines
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Fri, Feb 20 - Wed, Mar 4
United Airlines Logo
5:05 pm - 8:50 amIND-SCL
13h 45m1 stop
United Airlines Logo
10:45 pm - 3:51 pmSCL-IND
19h 06m1 stop
$764United Airlines
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Thu, Jan 15 - Thu, Jan 22
United Airlines Logo
9:05 am - 8:50 amIND-SCL
21h 45m2 stops
United Airlines Logo
10:45 pm - 5:52 pmSCL-IND
21h 07m2 stops
$769United Airlines
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Thu, Jan 15 - Thu, Jan 22

Avianca flights from Indianapolis to South America

Our best Avianca deals on Indianapolis to South America flight tickets
Avianca
Jan 14
IND9:50 amIndianapolis
10h 15m
1 stop
BOG8:05 pmBogotá El Dorado
Jan 31
BOG10:45 pmBogotá El Dorado
11h 43m
1 stop
IND10:28 amIndianapolis
$489
Find similar
Avianca
Jan 14
IND9:50 amIndianapolis
10h 15m
1 stop
BOG8:05 pmBogotá El Dorado
Jan 31
BOG3:00 pmBogotá El Dorado
19h 28m
2 stops
IND10:28 amIndianapolis
$492
Find similar
Avianca
Jan 31
IND7:43 pmIndianapolis
19h 02m
2 stops
CLO2:45 pmCali Alfonso B. Aragon Intl
Feb 5
CLO6:45 pmCali Alfonso B. Aragon Intl
15h 43m
2 stops
IND10:28 amIndianapolis
$508
Find similar

United Airlines flights from Indianapolis to South America

Our best United Airlines deals on Indianapolis to South America flight tickets
United Airlines
Feb 5
IND9:00 amIndianapolis
13h 35m
1 stop
BOG10:35 pmBogotá El Dorado
Feb 16
BOG1:30 amBogotá El Dorado
19h 21m
1 stop
IND8:51 pmIndianapolis
$557
Find similar
United Airlines
Feb 8
IND5:05 pmIndianapolis
48h 45m
2 stops
CLO5:50 pmCali Alfonso B. Aragon Intl
Feb 16
CLO3:11 pmCali Alfonso B. Aragon Intl
29h 40m
2 stops
IND8:51 pmIndianapolis
$565
Find similar
United Airlines
Dec 14
IND6:00 amIndianapolis
16h 05m
2 stops
MDE10:05 pmMedellín Jose Maria Cordova Intl
Dec 26
MDE1:15 amMedellín Jose Maria Cordova Intl
20h 44m
2 stops
IND9:59 pmIndianapolis
$762
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 1, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Sat 2/21

8:17 pm-1:13 pm

1 stop16h 56m

Cartagena Rafael Nunez

Tue 2/24

2:21 pm-10:38 pm

1 stop8h 17m

$256

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Sat 2/21

8:17 pm-1:13 pm

1 stop16h 56m

Cartagena Rafael Nunez

Tue 2/24

2:21 pm-10:38 pm

1 stop8h 17m

$273

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Sun 1/25

9:34 pm-12:50 pm

1 stop15h 16m

Bogotá El Dorado

Sun 2/1

1:45 pm-11:43 am

2 stops21h 58m

$362

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Tue 1/20

5:10 am-6:10 pm

1 stop13h 00m

Bogotá El Dorado

Mon 1/26

9:15 am-10:48 pm

1 stop13h 33m

$371

IndianapolisSao Paulo

IND - GRU

INDGRU

Indianapolis

Mon 5/4

4:35 pm-9:50 am

2 stops40h 15m

Sao Paulo Guarulhos Intl

Mon 5/18

9:00 pm-3:49 pm

2 stops19h 49m

$704

IndianapolisSao Paulo

IND - GRU

INDGRU

Indianapolis

Tue 5/19

10:30 am-9:05 am

1 stop21h 35m

Sao Paulo Guarulhos Intl

Wed 5/27

9:00 pm-8:35 pm

2 stops24h 35m

$709

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 1/15

12:27 pm-6:55 am

1 stop16h 28m

Santiago Arturo Merino Benitez

Thu 1/22

11:10 pm-10:36 am

1 stop13h 26m

$748

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Fri 2/20

12:24 pm-6:55 am

1 stop16h 31m

Santiago Arturo Merino Benitez

Wed 3/4

11:30 pm-12:12 pm

1 stop14h 42m

$751

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 1/15

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Thu 1/22

10:45 pm-3:51 pm

1 stop19h 06m

$764

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 1/15

9:05 am-8:50 am

2 stops21h 45m

Santiago Arturo Merino Benitez

Thu 1/22

10:45 pm-5:52 pm

2 stops21h 07m

$769

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Indianapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Indianapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $684. If you aren’t able to travel during the month of October, then book flights to South America from Indianapolis during February instead. Flights to South America in February, while not as cheap as those in October, still average around $751.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Indianapolis to South America is on a Tuesday when prices can be found for as low as $690. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Indianapolis to South America for around $873.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Indianapolis to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $783. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $812 on average. Flights to South America from Indianapolis in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $819 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Indianapolis for as low as $693 on momondo.

Can stopping save me money on Indianapolis to South America flights?

You could potentially save up to 61% on your flight if you consider stops on a Indianapolis to South America flight.

Cheap Indianapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South America

Fastest flight time

6h 25m

Direct flights

None
The fastest flight from Indianapolis to South America takes 6h 25m
There are no direct flights from Indianapolis to South America. There are no popular flight routes from Indianapolis to South America.
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  • When did momondo last update prices for flights from Indianapolis Airport to South America?

    Prices for flights from Indianapolis Airport to South America refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to South America?

  • How old do you have to be to fly from Indianapolis Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Indianapolis to South America

Compare and see reviews for airlines that fly from Indianapolis to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $263Free CancellationRating
6.3
8,156 reviews
Search Spirit Airlines flights
Copa AirlinesPriceFrom $420Free CancellationRating
7.6
1,560 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $426Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $531Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights
United AirlinesPriceFrom $538Free CancellationRating
7.4
9,065 reviews
Search United Airlines flights
DeltaPriceFrom $543Free CancellationRating
7.9
8,010 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to South America?

Finding the right flight to South America from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Indianapolis to South America with flexible booking policies on momondo?

Yes. All flights to South America from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to South America?

momondo provides multiple filters to help you find the best flight to South America from Indianapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Indianapolis to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indianapolis to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
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Flights to Califrom $202