What is the cheapest airline that flies from Indianapolis to South America?

Frontier, American Airlines, and JetBlue are the most popular carriers operating from Indianapolis to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Indianapolis according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indianapolis Airport to South America?

Prices for flights from Indianapolis Airport to South America refresh daily.

How many operators does momondo search for flights from Indianapolis Airport to South America?

The number of operators available for flights from Indianapolis Airport to South America is 4 as of November 2026.

How old do you have to be to fly from Indianapolis Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$179 Cheap Flights from Indianapolis to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Indianapolis to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:44 pmIND Indianapolis-CTG Cartagena Rafael Nunez

6h 44m1 stop Fort Lauderdale

1:49 pm - 10:21 pmCTG Cartagena Rafael Nunez-IND Indianapolis

8h 32m1 stop Fort Lauderdale

$378JetBlue

Fri, Jan 8 - Tue, Jan 12

6:00 am - 12:44 pmIND Indianapolis-CTG Cartagena Rafael Nunez

6h 44m1 stop Fort Lauderdale

1:49 pm - 10:21 pmCTG Cartagena Rafael Nunez-IND Indianapolis

8h 32m1 stop Fort Lauderdale

$415JetBlue

Fri, Jan 8 - Tue, Jan 12

9:17 pm - 1:36 pmIND Indianapolis-CTG Cartagena Rafael Nunez

16h 19m2 stops Washington, D.C. Reagan-National Miami

2:35 pm - 10:30 amCTG Cartagena Rafael Nunez-IND Indianapolis

19h 55m2 stops Miami Charlotte Douglas

$556American Airlines

Fri, Jan 1 - Sun, Jan 31

9:17 pm - 1:36 pmIND Indianapolis-CTG Cartagena Rafael Nunez

16h 19m2 stops Washington, D.C. Reagan-National Miami

4:38 pm - 12:15 pmCTG Cartagena Rafael Nunez-IND Indianapolis

19h 37m2 stops Miami Chicago O'Hare Intl

$556American Airlines

Fri, Jan 1 - Sun, Jan 31

6:00 am - 6:15 amIND Indianapolis-CLO Cali Alfonso B. Aragon Intl

24h 15m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:20 am - 9:55 amCLO Cali Alfonso B. Aragon Intl-IND Indianapolis

22h 35m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$656LATAM Airlines

Sat, Feb 27 - Tue, Mar 2

7:10 am - 6:59 pmIND Indianapolis-UIO Quito Mariscal Sucr

12h 49m1 stop Atlanta Hartsfield-Jackson

12:59 am - 10:32 amUIO Quito Mariscal Sucr-IND Indianapolis

8h 33m1 stop Atlanta Hartsfield-Jackson

$697LATAM Airlines

Thu, Apr 1 - Thu, Apr 29

6:00 am - 9:25 pmIND Indianapolis-UIO Quito Mariscal Sucr

15h 25m1 stop Atlanta Hartsfield-Jackson

12:55 am - 10:04 amUIO Quito Mariscal Sucr-IND Indianapolis

9h 09m1 stop Atlanta Hartsfield-Jackson

$718Delta

Fri, Dec 11 - Mon, Dec 21

8:00 am - 9:25 pmIND Indianapolis-UIO Quito Mariscal Sucr

13h 25m1 stop Atlanta Hartsfield-Jackson

12:55 am - 4:31 pmUIO Quito Mariscal Sucr-IND Indianapolis

15h 36m1 stop Atlanta Hartsfield-Jackson

$718Delta

Fri, Dec 11 - Sun, Dec 27

9:07 am - 7:15 pmIND Indianapolis-LIM Lima J Chavez Intl

34h 08m2 stops Chicago O'Hare Intl Panama City Tocumen Intl

2:15 am - 5:55 pmLIM Lima J Chavez Intl-IND Indianapolis

15h 40m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$858Copa Airlines

Sat, Feb 20 - Fri, Feb 26

5:00 am - 1:20 amIND Indianapolis-LIM Lima J Chavez Intl

20h 20m2 stops Chicago O'Hare Intl Panama City Tocumen Intl

10:30 am - 10:20 amLIM Lima J Chavez Intl-IND Indianapolis

23h 50m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$858Copa Airlines

Wed, Dec 2 - Sat, Dec 12

Cheap last minute flights

Enter your travel dates to find the best prices.

10:23 am - 9:25 pmIND Indianapolis-UIO Quito Mariscal Sucr

11h 02m1 stop Atlanta Hartsfield-Jackson

12:55 am - 5:31 pmUIO Quito Mariscal Sucr-IND Indianapolis

16h 36m1 stop Atlanta Hartsfield-Jackson

$833Delta

Wed, Nov 11 - Tue, Nov 17

6:26 pm - 6:52 pmIND Indianapolis-UIO Quito Mariscal Sucr

24h 26m2 stops Atlanta Hartsfield-Jackson Miami

8:55 am - 12:40 amUIO Quito Mariscal Sucr-IND Indianapolis

15h 45m2 stops Miami Atlanta Hartsfield-Jackson

$837LATAM Airlines

Wed, Nov 11 - Wed, Nov 18

6:02 pm - 6:52 pmIND Indianapolis-UIO Quito Mariscal Sucr

24h 50m2 stops New York John F Kennedy Intl Miami

12:55 am - 10:43 amUIO Quito Mariscal Sucr-IND Indianapolis

9h 48m1 stop Atlanta Hartsfield-Jackson

$837Delta

Wed, Nov 11 - Tue, Nov 17

9:00 am - 11:55 pmIND Indianapolis-LIM Lima J Chavez Intl

14h 55m1 stop Houston George Bush Intcntl

1:50 am - 8:09 pmLIM Lima J Chavez Intl-IND Indianapolis

18h 19m1 stop Houston George Bush Intcntl

$925United Airlines

Wed, Nov 11 - Mon, Feb 8

7:10 am - 10:15 pmIND Indianapolis-LIM Lima J Chavez Intl

15h 05m2 stops Chicago O'Hare Intl Newark

1:50 am - 5:56 pmLIM Lima J Chavez Intl-IND Indianapolis

16h 06m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$929United Airlines

Wed, Nov 11 - Mon, Feb 8

11:48 am - 9:20 pmIND Indianapolis-LIM Lima J Chavez Intl

9h 32m1 stop Atlanta Hartsfield-Jackson

12:10 pm - 12:40 amLIM Lima J Chavez Intl-IND Indianapolis

12h 30m1 stop Atlanta Hartsfield-Jackson

$945LATAM Airlines

Tue, Nov 10 - Tue, Nov 17

7:50 am - 9:32 pmIND Indianapolis-LIM Lima J Chavez Intl

13h 42m2 stops Dallas/Fort Worth Miami

10:55 pm - 1:46 pmLIM Lima J Chavez Intl-IND Indianapolis

14h 51m2 stops Miami Charlotte Douglas

$979American Airlines

Wed, Nov 11 - Tue, Feb 9

6:00 am - 9:32 pmIND Indianapolis-LIM Lima J Chavez Intl

15h 32m2 stops Charlotte Douglas Miami

7:00 am - 10:44 pmLIM Lima J Chavez Intl-IND Indianapolis

15h 44m1 stop Miami

$979American Airlines

Wed, Nov 11 - Tue, Feb 9

5:45 am - 10:45 pmIND Indianapolis-LIM Lima J Chavez Intl

17h 00m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

2:35 am - 7:22 pmLIM Lima J Chavez Intl-IND Indianapolis

16h 47m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$996Copa Airlines

Fri, Nov 13 - Sat, Nov 21

9:50 am - 1:20 amIND Indianapolis-LIM Lima J Chavez Intl

15h 30m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

2:35 am - 5:52 pmLIM Lima J Chavez Intl-IND Indianapolis

15h 17m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$996Copa Airlines

Fri, Nov 13 - Sat, Nov 21

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Copa Airlines flights from Indianapolis to South America

Our best Copa Airlines deals on Indianapolis to South America flight tickets

Copa Airlines

Dec 6

IND9:00 amIndianapolis

15h 05m

2 stops

BOG12:05 amBogotá El Dorado

Dec 13

BOG6:08 pmBogotá El Dorado

24h 22m

2 stops

IND6:30 pmIndianapolis

$766

Copa Airlines

Nov 18

IND9:10 amIndianapolis

14h 55m

2 stops

BOG12:05 amBogotá El Dorado

Nov 22

BOG6:08 pmBogotá El Dorado

24h 38m

2 stops

IND6:46 pmIndianapolis

$777

Copa Airlines

Nov 27

IND7:45 pmIndianapolis

13h 40m

2 stops

BOG9:25 amBogotá El Dorado

Nov 30

BOG10:00 amBogotá El Dorado

24h 20m

2 stops

IND10:20 amIndianapolis

$783

Delta flights from Indianapolis to South America

Our best Delta deals on Indianapolis to South America flight tickets

Delta

Dec 8

IND10:18 amIndianapolis

11h 07m

1 stop

UIO9:25 pmQuito Mariscal Sucr

Dec 21

UIO12:55 amQuito Mariscal Sucr

12h 53m

1 stop

IND1:48 pmIndianapolis

$718

Delta

Dec 12

IND2:06 pmIndianapolis

28h 46m

2 stops

UIO6:52 pmQuito Mariscal Sucr

Dec 21

UIO12:55 amQuito Mariscal Sucr

9h 09m

1 stop

IND10:04 amIndianapolis

$740

Delta

Dec 12

IND2:06 pmIndianapolis

28h 46m

2 stops

UIO6:52 pmQuito Mariscal Sucr

Dec 22

UIO8:55 amQuito Mariscal Sucr

25h 09m

2 stops

IND10:04 amIndianapolis

$755

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

IndianapolisCartagena

IND Indianapolis - CTG Cartagena Rafael Nunez

INDCTG

Indianapolis

Fri 1/8

6:00 am-12:44 pm

1 stop6h 44m

Cartagena Rafael Nunez

Tue 1/12

1:49 pm-10:21 pm

1 stop8h 32m

$378

IndianapolisCartagena

IND Indianapolis - CTG Cartagena Rafael Nunez

INDCTG

Indianapolis

Fri 1/8

6:00 am-12:44 pm

1 stop6h 44m

Cartagena Rafael Nunez

Tue 1/12

1:49 pm-10:21 pm

1 stop8h 32m

$415

IndianapolisCartagena

IND Indianapolis - CTG Cartagena Rafael Nunez

INDCTG

Indianapolis

Fri 1/1

9:17 pm-1:36 pm

2 stops16h 19m

Cartagena Rafael Nunez

Sun 1/31

2:35 pm-10:30 am

2 stops19h 55m

$556

IndianapolisCartagena

IND Indianapolis - CTG Cartagena Rafael Nunez

INDCTG

Indianapolis

Fri 1/1

9:17 pm-1:36 pm

2 stops16h 19m

Cartagena Rafael Nunez

Sun 1/31

4:38 pm-12:15 pm

2 stops19h 37m

$556

IndianapolisCali

IND Indianapolis - CLO Cali Alfonso B. Aragon Intl

INDCLO

Indianapolis

Sat 2/27

6:00 am-6:15 am

2 stops24h 15m

Cali Alfonso B. Aragon Intl

Tue 3/2

11:20 am-9:55 am

2 stops22h 35m

$656

IndianapolisQuito

IND Indianapolis - UIO Quito Mariscal Sucr

INDUIO

Indianapolis

Thu 4/1

7:10 am-6:59 pm

1 stop12h 49m

Quito Mariscal Sucr

Thu 4/29

12:59 am-10:32 am

1 stop8h 33m

$697

IndianapolisQuito

IND Indianapolis - UIO Quito Mariscal Sucr

INDUIO

Indianapolis

Fri 12/11

6:00 am-9:25 pm

1 stop15h 25m

Quito Mariscal Sucr

Mon 12/21

12:55 am-10:04 am

1 stop9h 09m

$718

IndianapolisQuito

IND Indianapolis - UIO Quito Mariscal Sucr

INDUIO

Indianapolis

Fri 12/11

8:00 am-9:25 pm

1 stop13h 25m

Quito Mariscal Sucr

Sun 12/27

12:55 am-4:31 pm

1 stop15h 36m

$718

IndianapolisLima

IND Indianapolis - LIM Lima J Chavez Intl

INDLIM

Indianapolis

Sat 2/20

9:07 am-7:15 pm

2 stops34h 08m

Lima J Chavez Intl

Fri 2/26

2:15 am-5:55 pm

2 stops15h 40m

$858

IndianapolisLima

IND Indianapolis - LIM Lima J Chavez Intl

INDLIM

Indianapolis

Wed 12/2

5:00 am-1:20 am

2 stops20h 20m

Lima J Chavez Intl

Sat 12/12

10:30 am-10:20 am

2 stops23h 50m

$858

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from Indianapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $640. If you aren’t able to travel during the month of January, then book flights to South America from Indianapolis during February instead. Flights to South America in February, while not as cheap as those in January, still average around $642.

How far in advance should I book a flight from Indianapolis to South America?

You are more likely to see cheaper flights to South America from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $901 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Indianapolis for as low as $730 on momondo.

Cheap Indianapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South America

Best Price Found	$179
Fastest flight time	6h 43m
Direct flights	None

The best one-way flight to South America from Indianapolis in the past 72 hours is $179. The best round-trip flight deal from Indianapolis to South America found on momondo in the last 72 hours is $378.

The fastest flight from Indianapolis to South America takes 6h 43m

There are no direct flights from Indianapolis to South America. There are no popular flight routes from Indianapolis to South America.

Search flight deals

Frequently asked questions about flying from Indianapolis to South America

When did momondo last update prices for flights from Indianapolis Airport to South America?
Prices for flights from Indianapolis Airport to South America refresh daily.
How many operators does momondo search for flights from Indianapolis Airport to South America?
The number of operators available for flights from Indianapolis Airport to South America is 4 as of November 2026.
How old do you have to be to fly from Indianapolis Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Indianapolis to South America

Compare and see reviews for airlines that fly from Indianapolis to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $325	Free Cancellation	Rating 7.8 8,699 reviews	Search Delta flights
American Airlines	PriceFrom $559	Free Cancellation	Rating 7.0 12,227 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $569	Free Cancellation	Rating 7.4 1,972 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $667	Free Cancellation	Rating 7.6 1,555 reviews	Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to South America?

Finding the right flight to South America from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Indianapolis to South America with flexible booking policies on momondo?

Yes. All flights to South America from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to South America?

momondo provides multiple filters to help you find the best flight to South America from Indianapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Indianapolis to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indianapolis to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.