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Cheap flights from Indianapolis to Knoxville from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Knoxville departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Indianapolis to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:20 pm - 10:00 pm
IND
-
TYS
9h 40m
2 stops
Multiple Airlines Logo
7:20 pm - 9:58 am
TYS
-
IND
14h 38m
1 stop
$235Multiple Airlines
Mon, Jul 27 - Fri, Jul 31
Multiple Airlines Logo
11:27 am - 10:01 pm
IND
-
TYS
10h 34m
1 stop
Multiple Airlines Logo
7:20 pm - 9:58 am
TYS
-
IND
14h 38m
1 stop
$238Multiple Airlines
Sat, Jul 25 - Fri, Jul 31
Multiple Airlines Logo
12:20 pm - 10:24 pm
IND
-
TYS
10h 04m
2 stops
Multiple Airlines Logo
3:56 pm - 9:24 pm
TYS
-
IND
5h 28m
1 stop
$242Multiple Airlines
Fri, Aug 7 - Sun, Aug 9
Multiple Airlines Logo
7:47 pm - 11:33 pm
IND
-
TYS
27h 46m
1 stop
Multiple Airlines Logo
6:00 pm - 9:24 pm
TYS
-
IND
27h 24m
1 stop
$244Multiple Airlines
Sun, Aug 2 - Sat, Aug 8
Allegiant Air Logo
9:20 pm - 11:19 pm
IND
-
TYS
25h 59m
1 stop
Allegiant Air Logo
8:29 pm - 10:12 am
TYS
-
IND
13h 43m
1 stop
$254Allegiant Air
Thu, Jul 30 - Thu, Aug 6
Multiple Airlines Logo
12:20 pm - 10:00 pm
IND
-
TYS
9h 40m
2 stops
Multiple Airlines Logo
7:20 pm - 6:15 pm
TYS
-
IND
22h 55m
1 stop
$257Multiple Airlines
Mon, Jul 27 - Mon, Aug 3
Multiple Airlines Logo
11:27 am - 10:01 pm
IND
-
TYS
10h 34m
1 stop
Multiple Airlines Logo
7:20 pm - 6:15 pm
TYS
-
IND
22h 55m
1 stop
$260Multiple Airlines
Sat, Jul 25 - Mon, Aug 3
Multiple Airlines Logo
12:20 pm - 10:24 pm
IND
-
TYS
10h 04m
2 stops
Multiple Airlines Logo
1:33 pm - 9:24 pm
TYS
-
IND
7h 51m
1 stop
$262Multiple Airlines
Fri, Aug 7 - Sun, Aug 9
Multiple Airlines Logo
12:20 pm - 10:24 pm
IND
-
TYS
10h 04m
2 stops
Multiple Airlines Logo
6:29 pm - 6:15 pm
TYS
-
IND
23h 46m
1 stop
$263Multiple Airlines
Fri, Aug 7 - Mon, Aug 10
Delta Logo
5:55 am - 11:10 am
IND
-
TYS
5h 15m
1 stop
Delta Logo
7:43 pm - 12:41 am
TYS
-
IND
4h 58m
1 stop
$265Delta
Tue, Jul 28 - Wed, Jul 29

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Delta flights from Indianapolis to Knoxville

Our best Delta deals on Indianapolis to Knoxville flight tickets
Delta
Jul 28
IND5:55 amIndianapolis
5h 15m
1 stop
TYS11:10 amKnoxville McGhee Tyson
Jul 29
TYS7:43 pmKnoxville McGhee Tyson
4h 58m
1 stop
IND12:41 amIndianapolis
$265
Delta
Jul 29
IND6:28 pmIndianapolis
5h 24m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Jul 30
TYS7:49 pmKnoxville McGhee Tyson
4h 52m
1 stop
IND12:41 amIndianapolis
$301
Delta
Jul 25
IND6:38 pmIndianapolis
5h 06m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Jul 28
TYS6:05 pmKnoxville McGhee Tyson
6h 36m
1 stop
IND12:41 amIndianapolis
$302

American Airlines flights from Indianapolis to Knoxville

Our best American Airlines deals on Indianapolis to Knoxville flight tickets
American Airlines
Jul 22
IND6:33 amIndianapolis
4h 32m
1 stop
TYS11:05 amKnoxville McGhee Tyson
Jul 26
TYS8:05 pmKnoxville McGhee Tyson
4h 04m
1 stop
IND12:09 amIndianapolis
$321
American Airlines
Jul 31
IND5:07 pmIndianapolis
4h 26m
1 stop
TYS9:33 pmKnoxville McGhee Tyson
Aug 2
TYS8:05 pmKnoxville McGhee Tyson
4h 04m
1 stop
IND12:09 amIndianapolis
$337
American Airlines
Jul 14
IND5:25 pmIndianapolis
4h 58m
1 stop
TYS10:23 pmKnoxville McGhee Tyson
Jul 16
TYS5:00 amKnoxville McGhee Tyson
3h 50m
1 stop
IND8:50 amIndianapolis
$437

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 7/27

12:20 pm-10:00 pm

2 stops9h 40m

Knoxville McGhee Tyson

Fri 7/31

7:20 pm-9:58 am

1 stop14h 38m

$235

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 7/25

11:27 am-10:01 pm

1 stop10h 34m

Knoxville McGhee Tyson

Fri 7/31

7:20 pm-9:58 am

1 stop14h 38m

$238

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 8/7

12:20 pm-10:24 pm

2 stops10h 04m

Knoxville McGhee Tyson

Sun 8/9

3:56 pm-9:24 pm

1 stop5h 28m

$242

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 8/2

7:47 pm-11:33 pm

1 stop27h 46m

Knoxville McGhee Tyson

Sat 8/8

6:00 pm-9:24 pm

1 stop27h 24m

$244

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 7/30

9:20 pm-11:19 pm

1 stop25h 59m

Knoxville McGhee Tyson

Thu 8/6

8:29 pm-10:12 am

1 stop13h 43m

$254

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 7/27

12:20 pm-10:00 pm

2 stops9h 40m

Knoxville McGhee Tyson

Mon 8/3

7:20 pm-6:15 pm

1 stop22h 55m

$257

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 7/25

11:27 am-10:01 pm

1 stop10h 34m

Knoxville McGhee Tyson

Mon 8/3

7:20 pm-6:15 pm

1 stop22h 55m

$260

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 8/7

12:20 pm-10:24 pm

2 stops10h 04m

Knoxville McGhee Tyson

Sun 8/9

1:33 pm-9:24 pm

1 stop7h 51m

$262

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 8/7

12:20 pm-10:24 pm

2 stops10h 04m

Knoxville McGhee Tyson

Mon 8/10

6:29 pm-6:15 pm

1 stop23h 46m

$263
Quickest round-trip

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 7/28

5:55 am-11:10 am

1 stop5h 15m

Knoxville McGhee Tyson

Wed 7/29

7:43 pm-12:41 am

1 stop4h 58m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Indianapolis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of June is, on average, the cheapest month to fly to Knoxville from Indianapolis, with most prices found around $0. If you aren’t able to travel during the month of June, then book flights to Knoxville from Indianapolis during November instead. Flights to Knoxville in November, while not as cheap as those in June, still average around $250.

When to book flights from Indianapolis to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Knoxville (IND to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Knoxville

Fastest flight time

7h 57m

Direct flights

None
The fastest flight from Indianapolis to Knoxville takes 7h 57m
There are no direct flights from Indianapolis to Knoxville. There are no popular flight routes from Indianapolis to Knoxville.
Search flight deals

Frequently asked questions about flying from Indianapolis to Knoxville

  • How far is Indianapolis to Knoxville McGhee Tyson by plane?

    The straight-line distance from Indianapolis to Knoxville McGhee Tyson is 289.8 mi. A reasonable flight in good conditions will take 7h 57m.

  • When did momondo last update prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Indianapolis Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Indianapolis to Knoxville?

Best airlines flying from Indianapolis to Knoxville

Compare and see reviews for airlines that fly from Indianapolis to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $218Free CancellationRating
7.1
11,764 reviews
Search American Airlines flights
United AirlinesPriceFrom $328Free CancellationRating
7.4
9,927 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indianapolis to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Indianapolis to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Indianapolis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indianapolis to Knoxville?

momondo helps you find the best flight between Indianapolis and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indianapolis to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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