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Cheap flights from Indianapolis to Knoxville from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Knoxville departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Indianapolis to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 10:13 pmIND-TYS
14h 43m1 stop
Multiple Airlines Logo
6:30 am - 7:53 pmTYS-IND
13h 23m1 stop
$228Multiple Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
Multiple Airlines Logo
9:29 pm - 5:43 pmIND-TYS
20h 14m1 stop
Multiple Airlines Logo
6:30 am - 7:53 pmTYS-IND
13h 23m1 stop
$230Multiple Airlines
Find Deal
Mon, Dec 1 - Sun, Dec 7
Multiple Airlines Logo
5:05 am - 12:57 pmIND-TYS
7h 52m1 stop
Multiple Airlines Logo
6:10 am - 8:08 amTYS-IND
25h 58m1 stop
$239Multiple Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
Multiple Airlines Logo
1:37 pm - 7:56 pmIND-TYS
6h 19m1 stop
Multiple Airlines Logo
6:30 am - 7:53 pmTYS-IND
13h 23m1 stop
$240Multiple Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 7
Multiple Airlines Logo
3:22 pm - 11:14 pmIND-TYS
7h 52m1 stop
Multiple Airlines Logo
6:30 am - 7:44 pmTYS-IND
37h 14m2 stops
$244Multiple Airlines
Find Deal
Mon, Nov 10 - Thu, Nov 13
Delta Logo
11:33 am - 2:52 pmIND-TYS
3h 19m1 stop
Delta Logo
3:57 pm - 9:42 pmTYS-IND
5h 45m1 stop
$251Delta
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Tue, Dec 2 - Tue, Dec 9
Delta Logo
7:57 pm - 11:41 pmIND-TYS
3h 44m1 stop
Delta Logo
5:40 am - 9:03 amTYS-IND
3h 23m1 stop
$284Delta
Find Deal
Mon, Dec 1 - Tue, Dec 9
American Airlines Logo
6:29 am - 10:52 amIND-TYS
4h 23m1 stop
American Airlines Logo
3:00 pm - 8:50 pmTYS-IND
5h 50m1 stop
$285American Airlines
Find Deal
Tue, Nov 25 - Tue, Dec 2
Allegiant Air Logo
7:30 am - 10:13 pmIND-TYS
14h 43m1 stop
Allegiant Air Logo
6:30 am - 10:47 pmTYS-IND
16h 17m1 stop
$296Allegiant Air
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Fri, Dec 5 - Mon, Dec 8
American Airlines Logo
6:51 am - 1:05 pmIND-TYS
6h 14m1 stop
American Airlines Logo
8:13 pm - 12:27 amTYS-IND
4h 14m1 stop
$311American Airlines
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Sat, Dec 6 - Sat, Dec 6

Delta flights from Indianapolis to Knoxville

Our best Delta deals on Indianapolis to Knoxville flight tickets
Delta
Dec 2
IND11:33 amIndianapolis
3h 19m
1 stop
TYS2:52 pmKnoxville McGhee Tyson
Dec 9
TYS3:57 pmKnoxville McGhee Tyson
5h 45m
1 stop
IND9:42 pmIndianapolis
$251
Find similar
Delta
Dec 1
IND7:57 pmIndianapolis
3h 44m
1 stop
TYS11:41 pmKnoxville McGhee Tyson
Dec 9
TYS5:40 amKnoxville McGhee Tyson
3h 23m
1 stop
IND9:03 amIndianapolis
$284
Find similar
Delta
Nov 26
IND2:20 pmIndianapolis
5h 46m
1 stop
TYS8:06 pmKnoxville McGhee Tyson
Dec 3
TYS3:57 pmKnoxville McGhee Tyson
5h 45m
1 stop
IND9:42 pmIndianapolis
$299
Find similar

American Airlines flights from Indianapolis to Knoxville

Our best American Airlines deals on Indianapolis to Knoxville flight tickets
American Airlines
Nov 25
IND6:29 amIndianapolis
4h 23m
1 stop
TYS10:52 amKnoxville McGhee Tyson
Dec 2
TYS3:00 pmKnoxville McGhee Tyson
5h 50m
1 stop
IND8:50 pmIndianapolis
$285
Find similar
American Airlines
Dec 6
IND6:51 amIndianapolis
6h 14m
1 stop
TYS1:05 pmKnoxville McGhee Tyson
Dec 6
TYS8:13 pmKnoxville McGhee Tyson
4h 14m
1 stop
IND12:27 amIndianapolis
$311
Find similar
American Airlines
Nov 10
IND7:00 pmIndianapolis
3h 51m
1 stop
TYS10:51 pmKnoxville McGhee Tyson
Nov 13
TYS8:04 pmKnoxville McGhee Tyson
4h 22m
1 stop
IND12:26 amIndianapolis
$502
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 12/5

7:30 am-10:13 pm

1 stop14h 43m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:53 pm

1 stop13h 23m

$228

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 12/1

9:29 pm-5:43 pm

1 stop20h 14m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:53 pm

1 stop13h 23m

$230

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 11/19

5:05 am-12:57 pm

1 stop7h 52m

Knoxville McGhee Tyson

Wed 11/26

6:10 am-8:08 am

1 stop25h 58m

$239

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 12/6

1:37 pm-7:56 pm

1 stop6h 19m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:53 pm

1 stop13h 23m

$240

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 11/10

3:22 pm-11:14 pm

1 stop7h 52m

Knoxville McGhee Tyson

Thu 11/13

6:30 am-7:44 pm

2 stops37h 14m

$244

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 12/2

11:33 am-2:52 pm

1 stop3h 19m

Knoxville McGhee Tyson

Tue 12/9

3:57 pm-9:42 pm

1 stop5h 45m

$251

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 12/1

7:57 pm-11:41 pm

1 stop3h 44m

Knoxville McGhee Tyson

Tue 12/9

5:40 am-9:03 am

1 stop3h 23m

$284

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 11/25

6:29 am-10:52 am

1 stop4h 23m

Knoxville McGhee Tyson

Tue 12/2

3:00 pm-8:50 pm

1 stop5h 50m

$285

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 12/5

7:30 am-10:13 pm

1 stop14h 43m

Knoxville McGhee Tyson

Mon 12/8

6:30 am-10:47 pm

1 stop16h 17m

$296

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 12/6

6:51 am-1:05 pm

1 stop6h 14m

Knoxville McGhee Tyson

Sat 12/6

8:13 pm-12:27 am

1 stop4h 14m

$311

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Indianapolis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Indianapolis, with most prices found around $238. If you aren’t able to travel during the month of December, then book flights to Knoxville from Indianapolis during June instead. Flights to Knoxville in June, while not as cheap as those in December, still average around $254.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Indianapolis to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $217. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Indianapolis to Knoxville for around $484.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Indianapolis to Knoxville when you can find flight prices for as low as $195. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $296.

When to book flights from Indianapolis to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Knoxville (IND to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Knoxville

Direct flights

None
There are no direct flights from Indianapolis to Knoxville. There are no popular flight routes from Indianapolis to Knoxville.
Search flight deals

  • How far is Indianapolis to Knoxville McGhee Tyson by plane?

    The straight-line distance from Indianapolis to Knoxville McGhee Tyson is 289.8 mi. A reasonable flight in good conditions will take 3h 19m.

  • When did momondo last update prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Indianapolis Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Indianapolis to Knoxville?

Best airlines flying from Indianapolis to Knoxville

Compare and see reviews for airlines that fly from Indianapolis to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $208Free CancellationRating
7.2
11,035 reviews
Search American Airlines flights
DeltaPriceFrom $217Free CancellationRating
7.9
7,998 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indianapolis to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Indianapolis to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Indianapolis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indianapolis to Knoxville?

momondo helps you find the best flight between Indianapolis and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indianapolis to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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