What is the cheapest airline that flies from Indianapolis to Knoxville McGhee Tyson?

Allegiant Air, United Airlines, and Delta are the most popular carriers operating from Indianapolis to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Indianapolis according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?

As of January 2026, there are 2 operators available to choose from for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Indianapolis Airport to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$101 Cheap Flights from Indianapolis to Knoxville in 2026

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Find the cheapest flights from Indianapolis to Knoxville

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:00 pm

IND

TYS

6h 00m

1 stop

8:40 am - 10:59 am

TYS

IND

26h 19m

1 stop

$226Multiple Airlines

Fri, Mar 6 - Fri, Mar 13

7:15 am - 1:15 pm

IND

TYS

6h 00m

1 stop

10:55 am - 5:53 pm

TYS

IND

6h 58m

1 stop

$251United Airlines

Wed, Feb 18 - Sat, Feb 21

10:00 am - 5:56 pm

IND

TYS

7h 56m

1 stop

4:54 pm - 9:21 am

TYS

IND

16h 27m

1 stop

$254Multiple Airlines

Wed, Mar 11 - Thu, Mar 12

1:57 pm - 8:40 pm

IND

TYS

6h 43m

1 stop

7:02 am - 3:17 pm

TYS

IND

8h 15m

2 stops

$256American Airlines

Wed, Feb 18 - Sat, Feb 21

9:00 am - 11:10 pm

IND

TYS

14h 10m

1 stop

11:50 am - 11:53 am

TYS

IND

24h 03m

1 stop

$259Allegiant Air

Sun, Feb 8 - Thu, Feb 12

3:47 pm - 8:47 pm

IND

TYS

5h 00m

1 stop

7:00 am - 11:21 am

TYS

IND

4h 21m

1 stop

$271United Airlines

Mon, Mar 23 - Thu, Mar 26

4:05 pm - 8:37 pm

IND

TYS

4h 32m

1 stop

7:25 pm - 11:59 pm

TYS

IND

4h 34m

1 stop

$277United Airlines

Wed, Mar 4 - Sat, Mar 7

6:00 am - 12:00 pm

IND

TYS

6h 00m

1 stop

6:21 pm - 4:13 pm

TYS

IND

21h 52m

2 stops

$280Multiple Airlines

Fri, Mar 6 - Fri, Mar 13

10:00 am - 5:56 pm

IND

TYS

7h 56m

1 stop

1:16 pm - 11:39 pm

TYS

IND

10h 23m

1 stop

$284Allegiant Air

Wed, Mar 11 - Fri, Mar 13

3:48 pm - 10:44 am

IND

TYS

18h 56m

2 stops

1:16 pm - 11:39 pm

TYS

IND

10h 23m

1 stop

$286Multiple Airlines

Wed, Mar 11 - Fri, Mar 13

United Airlines flights from Indianapolis to Knoxville

Our best United Airlines deals on Indianapolis to Knoxville flight tickets

United Airlines

Feb 18

IND7:15 amIndianapolis

6h 00m

1 stop

TYS1:15 pmKnoxville McGhee Tyson

Feb 21

TYS10:55 amKnoxville McGhee Tyson

6h 58m

1 stop

IND5:53 pmIndianapolis

$251

United Airlines

Mar 23

IND3:47 pmIndianapolis

5h 00m

1 stop

TYS8:47 pmKnoxville McGhee Tyson

Mar 26

TYS7:00 amKnoxville McGhee Tyson

4h 21m

1 stop

IND11:21 amIndianapolis

$271

United Airlines

Mar 4

IND4:05 pmIndianapolis

4h 32m

1 stop

TYS8:37 pmKnoxville McGhee Tyson

Mar 7

TYS7:25 pmKnoxville McGhee Tyson

4h 34m

1 stop

IND11:59 pmIndianapolis

$277

American Airlines flights from Indianapolis to Knoxville

Our best American Airlines deals on Indianapolis to Knoxville flight tickets

American Airlines

Feb 18

IND1:57 pmIndianapolis

6h 43m

1 stop

TYS8:40 pmKnoxville McGhee Tyson

Feb 21

TYS7:02 amKnoxville McGhee Tyson

8h 15m

2 stops

IND3:17 pmIndianapolis

$256

American Airlines

May 4

IND8:08 pmIndianapolis

3h 47m

1 stop

TYS11:55 pmKnoxville McGhee Tyson

May 8

TYS5:00 amKnoxville McGhee Tyson

4h 41m

1 stop

IND9:41 amIndianapolis

$294

American Airlines

Feb 20

IND1:12 pmIndianapolis

7h 55m

1 stop

TYS9:07 pmKnoxville McGhee Tyson

Feb 21

TYS7:51 amKnoxville McGhee Tyson

5h 34m

1 stop

IND1:25 pmIndianapolis

$299

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 3/6

6:00 am-12:00 pm

1 stop6h 00m

Knoxville McGhee Tyson

Fri 3/13

8:40 am-10:59 am

1 stop26h 19m

$226

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 2/18

7:15 am-1:15 pm

1 stop6h 00m

Knoxville McGhee Tyson

Sat 2/21

10:55 am-5:53 pm

1 stop6h 58m

$251

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 3/11

10:00 am-5:56 pm

1 stop7h 56m

Knoxville McGhee Tyson

Thu 3/12

4:54 pm-9:21 am

1 stop16h 27m

$254

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 2/18

1:57 pm-8:40 pm

1 stop6h 43m

Knoxville McGhee Tyson

Sat 2/21

7:02 am-3:17 pm

2 stops8h 15m

$256

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 2/8

9:00 am-11:10 pm

1 stop14h 10m

Knoxville McGhee Tyson

Thu 2/12

11:50 am-11:53 am

1 stop24h 03m

$259

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 3/23

3:47 pm-8:47 pm

1 stop5h 00m

Knoxville McGhee Tyson

Thu 3/26

7:00 am-11:21 am

1 stop4h 21m

$271

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 3/4

4:05 pm-8:37 pm

1 stop4h 32m

Knoxville McGhee Tyson

Sat 3/7

7:25 pm-11:59 pm

1 stop4h 34m

$277

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 3/6

6:00 am-12:00 pm

1 stop6h 00m

Knoxville McGhee Tyson

Fri 3/13

6:21 pm-4:13 pm

2 stops21h 52m

$280

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 3/11

10:00 am-5:56 pm

1 stop7h 56m

Knoxville McGhee Tyson

Fri 3/13

1:16 pm-11:39 pm

1 stop10h 23m

$284

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 3/11

3:48 pm-10:44 am

2 stops18h 56m

Knoxville McGhee Tyson

Fri 3/13

1:16 pm-11:39 pm

1 stop10h 23m

$286

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Indianapolis, with most prices found around $250. If you aren’t able to travel during the month of November, then book flights to Knoxville from Indianapolis during June instead. Flights to Knoxville in June, while not as cheap as those in November, still average around $254.

When to book flights from Indianapolis to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to Knoxville (IND to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Knoxville

Fastest flight time	4h 12m
Direct flights	None

The fastest flight from Indianapolis to Knoxville takes 4h 12m

There are no direct flights from Indianapolis to Knoxville. There are no popular flight routes from Indianapolis to Knoxville.

Search flight deals

How far is Indianapolis to Knoxville McGhee Tyson by plane?
The straight-line distance from Indianapolis to Knoxville McGhee Tyson is 289.8 mi. A reasonable flight in good conditions will take 4h 12m.
When did momondo last update prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport?
As of January 2026, there are 2 operators available to choose from for flights from Indianapolis Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Indianapolis Airport to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Indianapolis to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Indianapolis to Knoxville is American Airlines (75% of total bookings). The next most popular airline is Delta (25%).

Best airlines flying from Indianapolis to Knoxville

Compare and see reviews for airlines that fly from Indianapolis to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.9 8,128 reviews		Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,205 reviews		Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Murphy

Alcoa

Maryville

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indianapolis to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Indianapolis to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Indianapolis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indianapolis to Knoxville?

momondo helps you find the best flight between Indianapolis and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indianapolis to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.