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Cheap flights from Harrisburg to Knoxville from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Knoxville departing on 6/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Harrisburg to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
10:15 am - 9:15 pm
MDT
-
TYS
11h 00m
1 stop
Allegiant Air Logo
1:05 pm - 5:08 pm
TYS
-
MDT
28h 03m
1 stop
$248Allegiant Air
Mon, Jul 13 - Wed, Jul 22
Allegiant Air Logo
10:15 am - 9:15 pm
MDT
-
TYS
11h 00m
1 stop
Allegiant Air Logo
10:05 pm - 11:29 am
TYS
-
MDT
13h 24m
1 stop
$278Allegiant Air
Mon, Jul 13 - Mon, Jul 20
Allegiant Air Logo
10:15 am - 9:15 pm
MDT
-
TYS
11h 00m
1 stop
Allegiant Air Logo
4:20 pm - 1:20 pm
TYS
-
MDT
21h 00m
1 stop
$281Allegiant Air
Mon, Jul 13 - Tue, Jul 21
Allegiant Air Logo
10:15 am - 9:15 pm
MDT
-
TYS
11h 00m
1 stop
Allegiant Air Logo
4:20 pm - 1:20 pm
TYS
-
MDT
21h 00m
1 stop
$282Allegiant Air
Mon, Jul 13 - Tue, Jul 21
Allegiant Air Logo
5:34 pm - 10:23 pm
MDT
-
TYS
28h 49m
1 stop
Allegiant Air Logo
1:05 pm - 5:08 pm
TYS
-
MDT
28h 03m
1 stop
$283Allegiant Air
Wed, Jul 15 - Wed, Jul 22
Allegiant Air Logo
10:15 am - 9:15 pm
MDT
-
TYS
11h 00m
1 stop
Allegiant Air Logo
1:05 pm - 5:08 pm
TYS
-
MDT
28h 03m
1 stop
$287Allegiant Air
Mon, Jul 13 - Wed, Jul 22
Delta Logo
6:22 pm - 11:52 pm
MDT
-
TYS
5h 30m
1 stop
Delta Logo
7:15 am - 11:41 am
TYS
-
MDT
4h 26m
1 stop
$289Delta
Tue, Jul 14 - Tue, Jul 21
Allegiant Air Logo
9:50 am - 8:18 pm
MDT
-
TYS
10h 28m
1 stop
Allegiant Air Logo
9:00 am - 9:35 am
TYS
-
MDT
24h 35m
1 stop
$293Allegiant Air
Mon, Aug 10 - Wed, Aug 12
Allegiant Air Logo
2:10 pm - 3:03 pm
MDT
-
TYS
24h 53m
1 stop
Allegiant Air Logo
10:05 pm - 11:29 am
TYS
-
MDT
13h 24m
1 stop
$297Allegiant Air
Wed, Jul 15 - Mon, Jul 20
Allegiant Air Logo
2:10 pm - 3:03 pm
MDT
-
TYS
24h 53m
1 stop
Allegiant Air Logo
4:20 pm - 1:20 pm
TYS
-
MDT
21h 00m
1 stop
$302Allegiant Air
Wed, Jul 15 - Tue, Jul 21

Delta flights from Harrisburg to Knoxville

Our best Delta deals on Harrisburg to Knoxville flight tickets
Delta
Jul 14
MDT6:22 pmHarrisburg
5h 30m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Jul 21
TYS7:15 amKnoxville McGhee Tyson
4h 26m
1 stop
MDT11:41 amHarrisburg
$289
Delta
Jul 14
MDT6:22 pmHarrisburg
5h 30m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Jul 20
TYS5:25 pmKnoxville McGhee Tyson
5h 44m
1 stop
MDT11:09 pmHarrisburg
$309
Delta
Jul 14
MDT6:22 pmHarrisburg
5h 30m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Jul 21
TYS7:43 pmKnoxville McGhee Tyson
4h 10m
1 stop
MDT11:53 pmHarrisburg
$328

United Airlines flights from Harrisburg to Knoxville

Our best United Airlines deals on Harrisburg to Knoxville flight tickets
United Airlines
Oct 20
MDT6:15 amHarrisburg
4h 21m
1 stop
TYS10:36 amKnoxville McGhee Tyson
Oct 24
TYS10:42 amKnoxville McGhee Tyson
7h 43m
2 stops
MDT6:25 pmHarrisburg
$303
United Airlines
Jul 8
MDT10:30 amHarrisburg
3h 57m
1 stop
TYS2:27 pmKnoxville McGhee Tyson
Jul 11
TYS7:19 pmKnoxville McGhee Tyson
4h 11m
1 stop
MDT11:30 pmHarrisburg
$341
United Airlines
Aug 29
MDT7:59 pmHarrisburg
4h 00m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
Sep 2
TYS9:45 amKnoxville McGhee Tyson
4h 19m
1 stop
MDT2:04 pmHarrisburg
$374

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Harrisburg to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 7/13

10:15 am-9:15 pm

1 stop11h 00m

Knoxville McGhee Tyson

Wed 7/22

1:05 pm-5:08 pm

1 stop28h 03m

$248

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 7/13

10:15 am-9:15 pm

1 stop11h 00m

Knoxville McGhee Tyson

Mon 7/20

10:05 pm-11:29 am

1 stop13h 24m

$278

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 7/13

10:15 am-9:15 pm

1 stop11h 00m

Knoxville McGhee Tyson

Tue 7/21

4:20 pm-1:20 pm

1 stop21h 00m

$281

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 7/13

10:15 am-9:15 pm

1 stop11h 00m

Knoxville McGhee Tyson

Tue 7/21

4:20 pm-1:20 pm

1 stop21h 00m

$282

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Wed 7/15

5:34 pm-10:23 pm

1 stop28h 49m

Knoxville McGhee Tyson

Wed 7/22

1:05 pm-5:08 pm

1 stop28h 03m

$283

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 7/13

10:15 am-9:15 pm

1 stop11h 00m

Knoxville McGhee Tyson

Wed 7/22

1:05 pm-5:08 pm

1 stop28h 03m

$287
Quickest round-trip

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Tue 7/14

6:22 pm-11:52 pm

1 stop5h 30m

Knoxville McGhee Tyson

Tue 7/21

7:15 am-11:41 am

1 stop4h 26m

$289

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 8/10

9:50 am-8:18 pm

1 stop10h 28m

Knoxville McGhee Tyson

Wed 8/12

9:00 am-9:35 am

1 stop24h 35m

$293

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Wed 7/15

2:10 pm-3:03 pm

1 stop24h 53m

Knoxville McGhee Tyson

Mon 7/20

10:05 pm-11:29 am

1 stop13h 24m

$297

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Wed 7/15

2:10 pm-3:03 pm

1 stop24h 53m

Knoxville McGhee Tyson

Tue 7/21

4:20 pm-1:20 pm

1 stop21h 00m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Harrisburg to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Harrisburg, with most prices found around $271. If you aren’t able to travel during the month of January, then book flights to Knoxville from Harrisburg during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $308.

When to book flights from Harrisburg to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Knoxville (MDT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Knoxville

Fastest flight time

4h 01m

Direct flights

None
The fastest flight from Harrisburg to Knoxville takes 4h 01m
There are no direct flights from Harrisburg to Knoxville. There are no popular flight routes from Harrisburg to Knoxville.
Search flight deals

Frequently asked questions about flying from Harrisburg to Knoxville

  • How far is Harrisburg to Knoxville McGhee Tyson by plane?

    There are 484.3 mi between Harrisburg and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 4h 01m.

  • When did momondo last update prices for flights from Harrisburg Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Harrisburg Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Harrisburg Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Harrisburg Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Harrisburg Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Harrisburg to Knoxville?

Best airlines flying from Harrisburg to Knoxville

Compare and see reviews for airlines that fly from Harrisburg to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,631 reviews
Search American Airlines flights
United AirlinesPriceFrom $281Free CancellationRating
7.4
9,749 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Harrisburg with this policy.

How can momondo help me find flights from Harrisburg to Knoxville?

momondo helps you find the best flight between Harrisburg and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Harrisburg to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Harrisburg to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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