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Cheap flights from Gulfport to Knoxville from $166

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Gulfport to Knoxville departing on 3/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Gulfport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 pm - 11:52 pm
GPT
-
TYS
4h 52m
1 stop
Delta Logo
5:35 am - 9:24 am
TYS
-
GPT
4h 49m
1 stop
$491Delta
Fri, Feb 13 - Mon, Feb 16
American Airlines Logo
6:38 pm - 11:49 pm
GPT
-
TYS
4h 11m
1 stop
American Airlines Logo
6:05 pm - 11:57 pm
TYS
-
GPT
6h 52m
1 stop
$516American Airlines
Sat, Jun 6 - Thu, Jun 11
American Airlines Logo
6:38 pm - 11:49 pm
GPT
-
TYS
4h 11m
1 stop
American Airlines Logo
6:05 pm - 11:57 pm
TYS
-
GPT
6h 52m
1 stop
$565American Airlines
Thu, Jun 4 - Sun, Jun 7
Delta Logo
6:00 pm - 11:52 pm
GPT
-
TYS
4h 52m
1 stop
Delta Logo
5:00 pm - 9:54 pm
TYS
-
GPT
5h 54m
1 stop
$566Delta
Fri, Feb 13 - Sun, Feb 15
American Airlines Logo
6:31 am - 11:57 am
GPT
-
TYS
4h 26m
1 stop
American Airlines Logo
11:45 am - 3:59 pm
TYS
-
GPT
5h 14m
1 stop
$584American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
4:29 pm - 9:54 pm
GPT
-
TYS
4h 25m
1 stop
American Airlines Logo
5:47 pm - 11:57 pm
TYS
-
GPT
7h 10m
1 stop
$585American Airlines
Fri, Mar 13 - Mon, Mar 16
Multiple Airlines Logo
9:40 am - 11:01 pm
GPT
-
TYS
12h 21m
1 stop
Multiple Airlines Logo
7:00 am - 9:00 am
TYS
-
GPT
27h 00m
2 stops
$594Multiple Airlines
Fri, Feb 13 - Sun, Feb 15
United Airlines Logo
2:00 pm - 10:04 am
GPT
-
TYS
19h 04m
2 stops
United Airlines Logo
3:05 pm - 9:27 pm
TYS
-
GPT
7h 22m
1 stop
$655United Airlines
Sat, Jun 6 - Thu, Jun 11
United Airlines Logo
5:15 pm - 9:09 pm
GPT
-
TYS
26h 54m
2 stops
United Airlines Logo
7:15 am - 7:42 pm
TYS
-
GPT
13h 27m
1 stop
$656United Airlines
Thu, Jun 4 - Sun, Jun 7
Delta Logo
6:00 am - 11:08 am
GPT
-
TYS
4h 08m
1 stop
Delta Logo
6:41 pm - 9:54 pm
TYS
-
GPT
4h 13m
1 stop
$682Delta
Wed, Feb 18 - Sun, Feb 22

American Airlines flights from Gulfport to Knoxville

Our best American Airlines deals on Gulfport to Knoxville flight tickets
American Airlines
Jun 6
GPT6:38 pmGulfport Biloxi Regional
4h 11m
1 stop
TYS11:49 pmKnoxville McGhee Tyson
Jun 11
TYS6:05 pmKnoxville McGhee Tyson
6h 52m
1 stop
GPT11:57 pmGulfport Biloxi Regional
$516
American Airlines
Feb 17
GPT6:31 amGulfport Biloxi Regional
4h 26m
1 stop
TYS11:57 amKnoxville McGhee Tyson
Feb 21
TYS11:45 amKnoxville McGhee Tyson
5h 14m
1 stop
GPT3:59 pmGulfport Biloxi Regional
$584
American Airlines
Mar 13
GPT4:29 pmGulfport Biloxi Regional
4h 25m
1 stop
TYS9:54 pmKnoxville McGhee Tyson
Mar 16
TYS5:47 pmKnoxville McGhee Tyson
7h 10m
1 stop
GPT11:57 pmGulfport Biloxi Regional
$585

United Airlines flights from Gulfport to Knoxville

Our best United Airlines deals on Gulfport to Knoxville flight tickets
United Airlines
Feb 10
GPT4:42 pmGulfport Biloxi Regional
6h 02m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Feb 14
TYS9:10 amKnoxville McGhee Tyson
7h 51m
1 stop
GPT4:01 pmGulfport Biloxi Regional
$369
United Airlines
Feb 6
GPT5:13 pmGulfport Biloxi Regional
5h 31m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Feb 8
TYS9:05 amKnoxville McGhee Tyson
5h 17m
1 stop
GPT1:22 pmGulfport Biloxi Regional
$388
United Airlines
Feb 10
GPT4:42 pmGulfport Biloxi Regional
6h 02m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Feb 14
TYS9:10 amKnoxville McGhee Tyson
7h 51m
1 stop
GPT4:01 pmGulfport Biloxi Regional
$463

momondo Fare Finder

 
Customize your flight search to find flights from Gulfport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Gulfport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Fri 2/13

6:00 pm-11:52 pm

1 stop4h 52m

Knoxville McGhee Tyson

Mon 2/16

5:35 am-9:24 am

1 stop4h 49m

$491

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Sat 6/6

6:38 pm-11:49 pm

1 stop4h 11m

Knoxville McGhee Tyson

Thu 6/11

6:05 pm-11:57 pm

1 stop6h 52m

$516

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Thu 6/4

6:38 pm-11:49 pm

1 stop4h 11m

Knoxville McGhee Tyson

Sun 6/7

6:05 pm-11:57 pm

1 stop6h 52m

$565

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Fri 2/13

6:00 pm-11:52 pm

1 stop4h 52m

Knoxville McGhee Tyson

Sun 2/15

5:00 pm-9:54 pm

1 stop5h 54m

$566

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Tue 2/17

6:31 am-11:57 am

1 stop4h 26m

Knoxville McGhee Tyson

Sat 2/21

11:45 am-3:59 pm

1 stop5h 14m

$584

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Fri 3/13

4:29 pm-9:54 pm

1 stop4h 25m

Knoxville McGhee Tyson

Mon 3/16

5:47 pm-11:57 pm

1 stop7h 10m

$585

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Fri 2/13

9:40 am-11:01 pm

1 stop12h 21m

Knoxville McGhee Tyson

Sun 2/15

7:00 am-9:00 am

2 stops27h 00m

$594

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Sat 6/6

2:00 pm-10:04 am

2 stops19h 04m

Knoxville McGhee Tyson

Thu 6/11

3:05 pm-9:27 pm

1 stop7h 22m

$655

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Thu 6/4

5:15 pm-9:09 pm

2 stops26h 54m

Knoxville McGhee Tyson

Sun 6/7

7:15 am-7:42 pm

1 stop13h 27m

$656

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Wed 2/18

6:00 am-11:08 am

1 stop4h 08m

Knoxville McGhee Tyson

Sun 2/22

6:41 pm-9:54 pm

1 stop4h 13m

$682

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Gulfport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Gulfport, with most prices found around $228. If you aren’t able to travel during the month of August, then book flights to Knoxville from Gulfport during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $288.

When to book flights from Gulfport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Gulfport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Gulfport to Knoxville (GPT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gulfport to Knoxville

Fastest flight time

3h 39m

Direct flights

None
The fastest flight from Gulfport to Knoxville takes 3h 39m
There are no direct flights from Gulfport to Knoxville. There are no popular flight routes from Gulfport to Knoxville.
Search flight deals

  • How far is Gulfport Biloxi Regional to Knoxville McGhee Tyson by plane?

    Gulfport Biloxi Regional and Knoxville McGhee Tyson are 488.2 mi apart from one another. Typically, this will take 3h 39m by plane in normal conditions.

  • When did momondo last update prices for flights from Gulfport Biloxi Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Gulfport Biloxi Regional Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Gulfport Biloxi Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Gulfport Biloxi Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Gulfport Biloxi Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Gulfport to Knoxville?

Best airlines flying from Gulfport to Knoxville

Compare and see reviews for airlines that fly from Gulfport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $153Free CancellationRating
7.2
11,216 reviews
Search American Airlines flights
DeltaPriceFrom $164Free CancellationRating
7.9
8,138 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Gulfport to Knoxville?

Finding the right flight to Knoxville from Gulfport is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Gulfport to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Gulfport on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Gulfport to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Gulfport. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Gulfport to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Gulfport are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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