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Cheap flights from Greenville to Florida Keys from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Florida Keys departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Florida Keys

Cheap round-trip flights

American Airlines Logo
4:51 pm - 6:50 pmGSP-MIA
1h 59mnonstop
American Airlines Logo
1:40 pm - 3:43 pmMIA-GSP
2h 03mnonstop
$179American Airlines
Find Deal
Sun, Jan 18 - Thu, Jan 29
American Airlines Logo
4:51 pm - 6:50 pmGSP-MIA
1h 59mnonstop
American Airlines Logo
5:00 pm - 9:20 pmMIA-GSP
4h 20m1 stop
$224American Airlines
Find Deal
Sun, Jan 18 - Thu, Jan 29
Multiple Airlines Logo
3:23 pm - 9:02 amGSP-EYW
17h 39m1 stop
Multiple Airlines Logo
10:59 am - 8:44 pmEYW-GSP
9h 45m1 stop
$243Multiple Airlines
Find Deal
Fri, Oct 24 - Thu, Oct 30
Delta Logo
5:45 am - 9:26 amGSP-MIA
3h 41m1 stop
Delta Logo
6:00 am - 11:00 amMIA-GSP
5h 00m1 stop
$249Delta
Find Deal
Fri, Jan 9 - Thu, Jan 15
Delta Logo
1:58 pm - 7:53 pmGSP-EYW
5h 55m1 stop
Delta Logo
6:18 pm - 11:45 pmEYW-GSP
5h 27m1 stop
$249Delta
Find Deal
Mon, Nov 10 - Mon, Nov 24
Multiple Airlines Logo
9:39 pm - 11:05 amGSP-EYW
13h 26m1 stop
Multiple Airlines Logo
10:32 pm - 2:05 pmEYW-GSP
15h 33m1 stop
$262Multiple Airlines
Find Deal
Mon, Dec 15 - Tue, Dec 30
Southwest Logo
11:15 am - 9:00 pmGSP-MIA
9h 45m2 stops
Southwest Logo
7:35 am - 11:55 amMIA-GSP
4h 20m1 stop
$324Southwest
Find Deal
Fri, Jan 9 - Thu, Jan 15
Southwest Logo
7:40 am - 4:10 pmGSP-MIA
8h 30m1 stop
Southwest Logo
1:30 pm - 7:40 pmMIA-GSP
6h 10m1 stop
$326Southwest
Find Deal
Tue, Dec 9 - Tue, Dec 16
United Airlines Logo
4:29 pm - 1:52 pmGSP-EYW
45h 23m3 stops
United Airlines Logo
2:48 pm - 11:56 pmEYW-GSP
9h 08m1 stop
$612United Airlines
Find Deal
Fri, Oct 24 - Thu, Oct 30
United Airlines Logo
10:00 am - 2:04 pmGSP-EYW
28h 04m2 stops
United Airlines Logo
3:00 pm - 2:14 pmEYW-GSP
23h 14m2 stops
$688United Airlines
Find Deal
Sat, Nov 22 - Wed, Nov 26

Southwest flights from Greenville to Florida Keys

Our best Southwest deals on Greenville to Florida Keys flight tickets
Southwest
Jan 9
GSP11:15 amGreenville
9h 45m
2 stops
MIA9:00 pmMiami
Jan 15
MIA7:35 amMiami
4h 20m
1 stop
GSP11:55 amGreenville
$324
Find similar
Southwest
Dec 9
GSP7:40 amGreenville
8h 30m
1 stop
MIA4:10 pmMiami
Dec 16
MIA1:30 pmMiami
6h 10m
1 stop
GSP7:40 pmGreenville
$326
Find similar
Southwest
Oct 29
GSP6:05 amGreenville
8h 25m
2 stops
MIA2:30 pmMiami
Nov 4
MIA6:55 amMiami
9h 10m
2 stops
GSP4:05 pmGreenville
$331
Find similar

Delta flights from Greenville to Florida Keys

Our best Delta deals on Greenville to Florida Keys flight tickets
Delta
Jan 9
GSP5:45 amGreenville
3h 41m
1 stop
MIA9:26 amMiami
Jan 15
MIA6:00 amMiami
5h 00m
1 stop
GSP11:00 amGreenville
$249
Find similar
Delta
Jan 18
GSP5:45 amGreenville
3h 41m
1 stop
MIA9:26 amMiami
Jan 29
MIA3:35 pmMiami
5h 47m
1 stop
GSP9:22 pmGreenville
$259
Find similar
Delta
Jan 30
GSP7:55 pmGreenville
5h 02m
1 stop
MIA12:57 amMiami
Feb 2
MIA3:35 pmMiami
5h 47m
1 stop
GSP9:22 pmGreenville
$299
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from Greenville to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Sun 1/18

4:51 pm-6:50 pm

Nonstop1h 59m

Miami

Thu 1/29

1:40 pm-3:43 pm

Nonstop2h 03m

$179

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Sun 1/18

4:51 pm-6:50 pm

Nonstop1h 59m

Miami

Thu 1/29

5:00 pm-9:20 pm

1 stop4h 20m

$224

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Fri 10/24

3:23 pm-9:02 am

1 stop17h 39m

Key West

Thu 10/30

10:59 am-8:44 pm

1 stop9h 45m

$243

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Fri 1/9

5:45 am-9:26 am

1 stop3h 41m

Miami

Thu 1/15

6:00 am-11:00 am

1 stop5h 00m

$249

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Mon 11/10

1:58 pm-7:53 pm

1 stop5h 55m

Key West

Mon 11/24

6:18 pm-11:45 pm

1 stop5h 27m

$249

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Mon 12/15

9:39 pm-11:05 am

1 stop13h 26m

Key West

Tue 12/30

10:32 pm-2:05 pm

1 stop15h 33m

$262

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Fri 1/9

11:15 am-9:00 pm

2 stops9h 45m

Miami

Thu 1/15

7:35 am-11:55 am

1 stop4h 20m

$324

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 12/9

7:40 am-4:10 pm

1 stop8h 30m

Miami

Tue 12/16

1:30 pm-7:40 pm

1 stop6h 10m

$326

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Fri 10/24

4:29 pm-1:52 pm

3 stops45h 23m

Key West

Thu 10/30

2:48 pm-11:56 pm

1 stop9h 08m

$612

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Sat 11/22

10:00 am-2:04 pm

2 stops28h 04m

Key West

Wed 11/26

3:00 pm-2:14 pm

2 stops23h 14m

$688

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Greenville to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of July is another great option to travel to Florida Keys, with average flight prices from Greenville averaging around $378.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Greenville to Florida Keys is on a Friday when prices can be found for as low as $551. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $620.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Greenville to Florida Keys in the afternoon for as low as $418. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $612.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $395 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Greenville for as low as $341 on momondo.

Can stopping save me money on Greenville to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Greenville to Florida Keys.

Cheap Greenville to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Florida Keys

Fastest flight time

1h 53m

Direct flights

Every day

Airports in Florida Keys

1 airport
The fastest flight from Greenville to Florida Keys takes 1h 53m
Direct flights go from Greenville to Florida Keys every day.
There is 1 airport near Florida Keys: Miami (MIA)
Search flight deals

  • When did momondo last update prices for flights from Greenville Airport to Florida Keys?

    Prices for flights from Greenville Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Florida Keys?

  • How old do you have to be to fly from Greenville Airport to Florida Keys?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Greenville to Florida Keys?

Best airlines flying from Greenville to Florida Keys

Compare and see reviews for airlines that fly from Greenville to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
7,973 reviews
Search Delta flights
American AirlinesPriceFrom $253Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Florida Keys?

Finding the right flight to Florida Keys from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florida Keys quick and easy, saving you time and money.

Can I find flights from Greenville to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Greenville with this policy.

How can momondo help me find flights from Greenville to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to Florida Keys.

I’m not ready to book a flight from Greenville to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Greenville and alert you when they change.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Sat 10/25
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Find better results for your trip to Florida Keys

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