What is the cheapest airline that flies from Greenville to Florida Keys?

Southwest is the most popular carrier operating from Greenville to Florida Keys

How many flights depart from Greenville to Florida Keys on average per week?

As of August 2026, there are 26 flights per week flying from Greenville to Florida Keys. The most common day of the week flights depart is Mon, with 15% of flights taking off on this day.

What airlines fly to Florida Keys?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Greenville according to our data. Allegiant Air is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Greenville Airport to Florida Keys?

Prices for flights from Greenville Airport to Florida Keys were last updated today.

How many operators does momondo search for flights from Greenville Airport to Florida Keys?

As of August 2026, there are 4 operators available to choose from for flights from Greenville Airport to Florida Keys.

How old do you have to be to fly from Greenville Airport to Florida Keys?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$127 Cheap Flights from Greenville to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:07 am - 12:19 pmGSP Greenville-EYW Key West

26h 12m1 stop Tampa

10:59 am - 8:45 amEYW Key West-GSP Greenville

21h 46m1 stop Orlando

$178Breeze Airways

Thu, Sep 10 - Thu, Sep 17

10:07 am - 12:19 pmGSP Greenville-EYW Key West

26h 12m1 stop Tampa

10:59 am - 7:49 pmEYW Key West-GSP Greenville

8h 50m1 stop Orlando

$180Breeze Airways

Thu, Sep 10 - Thu, Sep 17

3:40 pm - 12:31 pmGSP Greenville-EYW Key West

20h 51m1 stop Tampa

12:59 pm - 5:23 pmEYW Key West-GSP Greenville

4h 24m1 stop Tampa

$182Breeze Airways

Sun, Sep 6 - Fri, Sep 11

12:09 pm - 6:01 pmGSP Greenville-EYW Key West

5h 52m1 stop Charlotte Douglas

7:08 am - 11:24 amEYW Key West-GSP Greenville

4h 16m1 stop Charlotte Douglas

$319American Airlines

Mon, Jan 18 - Sun, Jan 24

8:15 am - 1:35 pmGSP Greenville-MIA Miami

5h 20m1 stop Baltimore/Washington

11:45 am - 6:20 pmMIA Miami-GSP Greenville

6h 35m1 stop Nashville Intl

$331Southwest

Tue, Sep 8 - Thu, Sep 10

8:15 am - 4:25 pmGSP Greenville-MIA Miami

8h 10m1 stop Baltimore/Washington

5:00 pm - 10:55 pmMIA Miami-GSP Greenville

5h 55m1 stop Nashville Intl

$331Southwest

Mon, Nov 9 - Thu, Nov 12

6:00 am - 9:51 amGSP Greenville-EYW Key West

3h 51m1 stop Miami

6:27 pm - 10:53 pmEYW Key West-GSP Greenville

4h 26m1 stop Charlotte Douglas

$343American Airlines

Fri, Sep 11 - Tue, Sep 15

8:59 am - 4:58 pmGSP Greenville-EYW Key West

7h 59m2 stops Charlotte Douglas Miami

1:52 pm - 6:55 pmEYW Key West-GSP Greenville

5h 03m1 stop Charlotte Douglas

$367American Airlines

Wed, Oct 28 - Tue, Nov 3

7:20 am - 7:06 pmGSP Greenville-MIA Miami

11h 46m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:00 pmMIA Miami-GSP Greenville

17h 00m1 stop Atlanta Hartsfield-Jackson

$375Delta

Sat, Sep 26 - Sat, Oct 3

5:45 am - 7:05 pmGSP Greenville-MIA Miami

13h 20m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:00 pmMIA Miami-GSP Greenville

17h 00m1 stop Atlanta Hartsfield-Jackson

$375Delta

Wed, Sep 30 - Sat, Oct 3

Cheap last minute flights

Enter your travel dates to find the best prices.

8:13 pm - 3:02 pmGSP Greenville-EYW Key West

18h 49m1 stop Tampa

1:11 pm - 3:06 pmEYW Key West-GSP Greenville

25h 55m1 stop Tampa

$318Multiple Airlines

Fri, Aug 21 - Mon, Aug 24

6:19 pm - 9:10 amGSP Greenville-EYW Key West

38h 51m2 stops Cincinnati Cinci./N. Kentucky Orlando Sanford Intl

1:11 pm - 3:06 pmEYW Key West-GSP Greenville

25h 55m1 stop Tampa

$345Multiple Airlines

Fri, Aug 21 - Mon, Aug 24

8:13 pm - 3:02 pmGSP Greenville-EYW Key West

18h 49m1 stop Tampa

1:14 pm - 7:57 amEYW Key West-GSP Greenville

42h 43m2 stops Tampa Fort Lauderdale

$378Multiple Airlines

Fri, Aug 21 - Tue, Aug 25

2:51 pm - 7:57 pmGSP Greenville-EYW Key West

5h 06m1 stop Atlanta Hartsfield-Jackson

7:40 am - 12:41 pmEYW Key West-GSP Greenville

5h 01m1 stop Atlanta Hartsfield-Jackson

$409Delta

Fri, Aug 21 - Mon, Aug 24

6:00 am - 9:44 amGSP Greenville-EYW Key West

3h 44m1 stop Miami

4:50 pm - 9:50 pmEYW Key West-GSP Greenville

5h 00m1 stop Charlotte Douglas

$411American Airlines

Fri, Aug 21 - Tue, Aug 25

2:51 pm - 7:57 pmGSP Greenville-EYW Key West

5h 06m1 stop Atlanta Hartsfield-Jackson

7:40 am - 12:41 pmEYW Key West-GSP Greenville

5h 01m1 stop Atlanta Hartsfield-Jackson

$424Delta

Fri, Aug 21 - Mon, Aug 24

2:51 pm - 7:57 pmGSP Greenville-EYW Key West

5h 06m1 stop Atlanta Hartsfield-Jackson

7:40 am - 12:41 pmEYW Key West-GSP Greenville

5h 01m1 stop Atlanta Hartsfield-Jackson

$439Delta

Fri, Aug 21 - Mon, Aug 24

6:00 am - 9:44 amGSP Greenville-EYW Key West

3h 44m1 stop Miami

1:35 pm - 6:10 pmEYW Key West-GSP Greenville

4h 35m1 stop Miami

$463American Airlines

Thu, Aug 20 - Sat, Aug 22

6:45 am - 2:05 pmGSP Greenville-MIA Miami

7h 20m2 stops Nashville Intl Houston Hobby

2:20 pm - 7:00 pmMIA Miami-GSP Greenville

4h 40m1 stop Baltimore/Washington

$498Southwest

Sat, Aug 22 - Sat, Aug 29

6:45 am - 4:15 pmGSP Greenville-MIA Miami

9h 30m2 stops Nashville Intl Baltimore/Washington

7:00 am - 2:55 pmMIA Miami-GSP Greenville

7h 55m2 stops Orlando Nashville Intl

$503Southwest

Sat, Aug 22 - Sat, Aug 29

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Southwest flights from Greenville to Florida Keys

Our best Southwest deals on Greenville to Florida Keys flight tickets

Southwest

Sep 16

GSP1:20 pmGreenville

7h 00m

1 stop

MIA8:20 pmMiami

Sep 23

MIA11:50 amMiami

7h 40m

1 stop

GSP7:30 pmGreenville

$331

Southwest

Sep 16

GSP11:00 amGreenville

4h 30m

1 stop

MIA3:30 pmMiami

Sep 23

MIA7:30 amMiami

9h 15m

2 stops

GSP4:45 pmGreenville

$336

Southwest

Sep 16

GSP11:00 amGreenville

9h 05m

2 stops

MIA8:05 pmMiami

Sep 23

MIA7:10 amMiami

9h 35m

2 stops

GSP4:45 pmGreenville

$341

American Airlines flights from Greenville to Florida Keys

Our best American Airlines deals on Greenville to Florida Keys flight tickets

American Airlines

Jan 18

GSP12:09 pmGreenville

5h 52m

1 stop

EYW6:01 pmKey West

Jan 24

EYW7:08 amKey West

4h 16m

1 stop

GSP11:24 amGreenville

$319

American Airlines

Sep 11

GSP6:00 amGreenville

3h 51m

1 stop

EYW9:51 amKey West

Sep 15

EYW6:27 pmKey West

4h 26m

1 stop

GSP10:53 pmGreenville

$343

American Airlines

Oct 28

GSP10:03 amGreenville

9h 30m

2 stops

EYW7:33 pmKey West

Nov 3

EYW1:52 pmKey West

5h 03m

1 stop

GSP6:55 pmGreenville

$367

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Thu 9/10

10:07 am-12:19 pm

1 stop26h 12m

Key West

Thu 9/17

10:59 am-8:45 am

1 stop21h 46m

$178

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Thu 9/10

10:07 am-12:19 pm

1 stop26h 12m

Key West

Thu 9/17

10:59 am-7:49 pm

1 stop8h 50m

$180

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Sun 9/6

3:40 pm-12:31 pm

1 stop20h 51m

Key West

Fri 9/11

12:59 pm-5:23 pm

1 stop4h 24m

$182

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Mon 1/18

12:09 pm-6:01 pm

1 stop5h 52m

Key West

Sun 1/24

7:08 am-11:24 am

1 stop4h 16m

$319

GreenvilleMiami

GSP Greenville - MIA Miami

GSPMIA

Greenville

Tue 9/8

8:15 am-1:35 pm

1 stop5h 20m

Miami

Thu 9/10

11:45 am-6:20 pm

1 stop6h 35m

$331

GreenvilleMiami

GSP Greenville - MIA Miami

GSPMIA

Greenville

Mon 11/9

8:15 am-4:25 pm

1 stop8h 10m

Miami

Thu 11/12

5:00 pm-10:55 pm

1 stop5h 55m

$331

Quickest round-trip

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Fri 9/11

6:00 am-9:51 am

1 stop3h 51m

Key West

Tue 9/15

6:27 pm-10:53 pm

1 stop4h 26m

$343

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Wed 10/28

8:59 am-4:58 pm

2 stops7h 59m

Key West

Tue 11/3

1:52 pm-6:55 pm

1 stop5h 03m

$367

GreenvilleMiami

GSP Greenville - MIA Miami

GSPMIA

Greenville

Sat 9/26

7:20 am-7:06 pm

1 stop11h 46m

Miami

Sat 10/3

6:00 am-11:00 pm

1 stop17h 00m

$375

GreenvilleMiami

GSP Greenville - MIA Miami

GSPMIA

Greenville

Wed 9/30

5:45 am-7:05 pm

1 stop13h 20m

Miami

Sat 10/3

6:00 am-11:00 pm

1 stop17h 00m

$375

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of February is another great option to travel to Florida Keys, with average flight prices from Greenville averaging around $372.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Greenville to Florida Keys is on a Thursday when prices can be found for as low as $591. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $697.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Greenville to Florida Keys in the afternoon for as low as $432. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights at noon are often more expensive with an average ticket price of $1,163.

How far in advance should I book a flight from Greenville to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $439 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Greenville for as low as $288 on momondo.

Can stopping save me money on Greenville to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Greenville to Florida Keys.

Cheap Greenville to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Florida Keys

Best Price Found	$127
Fastest flight time	1h 56m
Direct flights	Every day
Airports in Florida Keys	3 airports

The best one-way flight to Florida Keys from Greenville in the past 72 hours is $127. The best round-trip flight deal from Greenville to Florida Keys found on momondo in the last 72 hours is $178.

The fastest flight from Greenville to Florida Keys takes 1h 56m

Direct flights go from Greenville to Florida Keys every day.

There are 3 airports in Florida Keys. From Greenville there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from Greenville to Florida Keys

When did momondo last update prices for flights from Greenville Airport to Florida Keys?
Prices for flights from Greenville Airport to Florida Keys were last updated today.
How many operators does momondo search for flights from Greenville Airport to Florida Keys?
As of August 2026, there are 4 operators available to choose from for flights from Greenville Airport to Florida Keys.
How old do you have to be to fly from Greenville Airport to Florida Keys?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Greenville to Florida Keys?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Greenville to Florida Keys is Embraer 175 (Enhanced Winglets) (15.62% of total bookings). The next most popular plane models are Airbus A220-300 (14.66%), Embraer 175 (14.64%), and Canadair (Bombardier) Regional Jet 900 (10.77%).

Best airlines flying from Greenville to Florida Keys

Compare and see reviews for airlines that fly from Greenville to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $76	Free Cancellation	Rating 7.3 676 reviews	Search Allegiant Air flights
Delta	PriceFrom $125	Free Cancellation	Rating 7.8 8,504 reviews	Search Delta flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.1 11,968 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Florida Keys?

Finding the right flight to Florida Keys from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florida Keys quick and easy, saving you time and money.

Can I find flights from Greenville to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Greenville with this policy.

How can momondo help me find flights from Greenville to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to Florida Keys.

I’m not ready to book a flight from Greenville to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Greenville and alert you when they change.