Cheap flights from Houston George Bush Intcntl Airport to St. Louis from $65

In general, January is the cheapest month to fly from Houston George Bush Intcntl Airport to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $303. The month of September is another great option to travel to St. Louis, with average flight prices from Houston George Bush Intcntl Airport averaging around $315.

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $329. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $395. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Houston George Bush Intcntl Airport in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $341 when looking at flights departing in the afternoon. In the evening is when there is more demand to fly to St. Louis, so prices are often more expensive at around $469 per ticket.

Fly from Houston George Bush Intcntl to Lambert-St Louis for the best Houston George Bush Intcntl - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Houston George Bush Intcntl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Houston George Bush Intcntl Airport for as low as $217 on momondo.

No. A direct flight is the cheapest option for a flight between Houston George Bush Intcntl Airport to St. Louis.

As of May 2026, prices for Houston George Bush Intcntl Airport to St. Louis flights are approximately 18% more expensive when compared to flights at the same time last year.

Dallas (DFW) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Dallas (DFW) offer the lowest average round-trip price of $180.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 4h 49m.

Dallas (DFW) has the shortest average layover time for this route: 1h 04m.

The number of flights available between Houston George Bush Intcntl Airport and St. Louis is 12 per day as of May 2026. The most frequent departure time is 1:00PM, with 40% of daily flights leaving in the afternoon.

86 flights are operational weekly from Houston George Bush Intcntl Airport to St. Louis as of May 2026. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.