Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Gainesville to Knoxville from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Gainesville to Knoxville departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Gainesville to Knoxville

Cheap round-trip flights

American Airlines Logo
4:43 pm - 11:03 pmGNV-TYS
6h 20m1 stop
American Airlines Logo
5:19 pm - 11:13 pmTYS-GNV
5h 54m1 stop
$229American Airlines
Find Deal
Wed, Sep 10 - Sat, Sep 13
American Airlines Logo
4:43 pm - 11:03 pmGNV-TYS
6h 20m1 stop
American Airlines Logo
5:19 pm - 11:59 pmTYS-GNV
6h 40m2 stops
$234American Airlines
Find Deal
Wed, Sep 10 - Sat, Sep 13
Delta Logo
6:35 pm - 11:48 pmGNV-TYS
5h 13m1 stop
Delta Logo
5:45 am - 9:32 amTYS-GNV
3h 47m1 stop
$239Delta
Find Deal
Tue, Sep 2 - Sat, Sep 6
Delta Logo
4:01 pm - 8:02 pmGNV-TYS
4h 01m1 stop
Delta Logo
5:45 am - 9:25 amTYS-GNV
3h 40m1 stop
$268Delta
Find Deal
Mon, Sep 15 - Mon, Sep 22
Delta Logo
6:45 pm - 11:44 pmGNV-TYS
4h 59m1 stop
Delta Logo
5:45 am - 9:25 amTYS-GNV
3h 40m1 stop
$278Delta
Find Deal
Sat, Sep 13 - Mon, Sep 15
American Airlines Logo
4:43 pm - 11:03 pmGNV-TYS
6h 20m1 stop
American Airlines Logo
5:05 am - 10:21 amTYS-GNV
5h 16m1 stop
$283American Airlines
Find Deal
Wed, Sep 3 - Wed, Sep 10
American Airlines Logo
6:13 am - 1:43 pmGNV-TYS
7h 30m2 stops
American Airlines Logo
5:19 pm - 11:59 pmTYS-GNV
6h 40m2 stops
$288American Airlines
Find Deal
Wed, Sep 10 - Sat, Sep 13
American Airlines Logo
2:55 pm - 6:54 pmGNV-TYS
3h 59m1 stop
American Airlines Logo
5:19 pm - 11:59 pmTYS-GNV
6h 40m2 stops
$294American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
6:25 am - 12:23 pmGNV-TYS
5h 58m1 stop
American Airlines Logo
5:05 am - 10:21 amTYS-GNV
5h 16m1 stop
$327American Airlines
Find Deal
Thu, Sep 11 - Mon, Sep 15
American Airlines Logo
6:13 am - 1:43 pmGNV-TYS
7h 30m2 stops
American Airlines Logo
7:43 pm - 11:26 pmTYS-GNV
3h 43m1 stop
$328American Airlines
Find Deal
Fri, Sep 26 - Wed, Oct 8

American Airlines flights from Gainesville to Knoxville

Our best American Airlines deals on Gainesville to Knoxville flight tickets
American Airlines
Sep 10
GNV4:43 pmGainesville Regional
6h 20m
1 stop
TYS11:03 pmKnoxville McGhee Tyson
Sep 13
TYS5:19 pmKnoxville McGhee Tyson
5h 54m
1 stop
GNV11:13 pmGainesville Regional
$229
Find similar
American Airlines
Sep 10
GNV4:43 pmGainesville Regional
6h 20m
1 stop
TYS11:03 pmKnoxville McGhee Tyson
Sep 13
TYS5:19 pmKnoxville McGhee Tyson
6h 40m
2 stops
GNV11:59 pmGainesville Regional
$234
Find similar
American Airlines
Sep 3
GNV4:43 pmGainesville Regional
6h 20m
1 stop
TYS11:03 pmKnoxville McGhee Tyson
Sep 10
TYS5:05 amKnoxville McGhee Tyson
5h 16m
1 stop
GNV10:21 amGainesville Regional
$283
Find similar

Delta flights from Gainesville to Knoxville

Our best Delta deals on Gainesville to Knoxville flight tickets
Delta
Sep 2
GNV6:35 pmGainesville Regional
5h 13m
1 stop
TYS11:48 pmKnoxville McGhee Tyson
Sep 6
TYS5:45 amKnoxville McGhee Tyson
3h 47m
1 stop
GNV9:32 amGainesville Regional
$239
Find similar
Delta
Sep 15
GNV4:01 pmGainesville Regional
4h 01m
1 stop
TYS8:02 pmKnoxville McGhee Tyson
Sep 22
TYS5:45 amKnoxville McGhee Tyson
3h 40m
1 stop
GNV9:25 amGainesville Regional
$268
Find similar
Delta
Sep 13
GNV6:45 pmGainesville Regional
4h 59m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Sep 15
TYS5:45 amKnoxville McGhee Tyson
3h 40m
1 stop
GNV9:25 amGainesville Regional
$278
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 9/10

4:43 pm-11:03 pm

1 stop6h 20m

Knoxville McGhee Tyson

Sat 9/13

5:19 pm-11:13 pm

1 stop5h 54m

$229

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 9/10

4:43 pm-11:03 pm

1 stop6h 20m

Knoxville McGhee Tyson

Sat 9/13

5:19 pm-11:59 pm

2 stops6h 40m

$234

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 9/2

6:35 pm-11:48 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sat 9/6

5:45 am-9:32 am

1 stop3h 47m

$239

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 9/15

4:01 pm-8:02 pm

1 stop4h 01m

Knoxville McGhee Tyson

Mon 9/22

5:45 am-9:25 am

1 stop3h 40m

$268

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 9/13

6:45 pm-11:44 pm

1 stop4h 59m

Knoxville McGhee Tyson

Mon 9/15

5:45 am-9:25 am

1 stop3h 40m

$278

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 9/3

4:43 pm-11:03 pm

1 stop6h 20m

Knoxville McGhee Tyson

Wed 9/10

5:05 am-10:21 am

1 stop5h 16m

$283

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 9/10

6:13 am-1:43 pm

2 stops7h 30m

Knoxville McGhee Tyson

Sat 9/13

5:19 pm-11:59 pm

2 stops6h 40m

$288

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 9/2

2:55 pm-6:54 pm

1 stop3h 59m

Knoxville McGhee Tyson

Sat 9/6

5:19 pm-11:59 pm

2 stops6h 40m

$294

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 9/11

6:25 am-12:23 pm

1 stop5h 58m

Knoxville McGhee Tyson

Mon 9/15

5:05 am-10:21 am

1 stop5h 16m

$327

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 9/26

6:13 am-1:43 pm

2 stops7h 30m

Knoxville McGhee Tyson

Wed 10/8

7:43 pm-11:26 pm

1 stop3h 43m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Gainesville to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Gainesville, with most prices found around $298. If you aren’t able to travel during the month of August, then book flights to Knoxville from Gainesville during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $356.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Gainesville to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $454. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Gainesville to Knoxville for around $664.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Gainesville to Knoxville when you can find flight prices for as low as $463. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $684.

What is the cheapest Gainesville Regional to Knoxville McGhee Tyson flight route?

Fly from Gainesville Regional to Knoxville McGhee Tyson for the best Gainesville Regional - Knoxville McGhee Tyson flight prices

What cabin class options are available on Gainesville Regional to Knoxville McGhee Tyson flights?

There are 1 cabin classes available to choose from on Gainesville Regional to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Gainesville to Knoxville flights?

You could potentially save up to 6% on your flight if you consider stops on a Gainesville to Knoxville flight.

When to book flights from Gainesville to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Gainesville to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Gainesville to Knoxville (GNV to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gainesville to Knoxville

Best Price Found

$160

Fastest flight time

3h 07m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Gainesville in the past 72 hours is $160. The best round-trip flight deal from Gainesville to Knoxville found on momondo in the last 72 hours is $229.
The fastest flight from Gainesville to Knoxville takes 3h 07m
There are no direct flights from Gainesville to Knoxville. Popular non-direct route for this connection is Gainesville Regional Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Gainesville Regional to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 445.3 mi away from Gainesville Regional. Flights usually cover this in 3h 07m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Gainesville Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Gainesville to Knoxville?

Best airlines flying from Gainesville to Knoxville

Compare and see reviews for airlines that fly from Gainesville to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $228Free CancellationRating
7.9
7,982 reviews
Search Delta flights
American AirlinesPriceFrom $313Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Lenoir City
Alcoa
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Gainesville to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Gainesville.

Can I find flights from Gainesville to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Gainesville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Gainesville to Knoxville?

momondo helps you find the best flight between Gainesville and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Gainesville to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Gainesville to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 8/25
Mon 9/1
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States