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Cheap flights from Gainesville to Knoxville from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Gainesville to Knoxville departing on 12/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Gainesville to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:33 pm - 11:59 pmGNV-TYS
6h 26m1 stop
American Airlines Logo
9:04 am - 1:27 pmTYS-GNV
4h 23m1 stop
$348American Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
American Airlines Logo
5:33 pm - 11:59 pmGNV-TYS
6h 26m1 stop
American Airlines Logo
2:55 pm - 11:58 pmTYS-GNV
9h 03m2 stops
$353American Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
Delta Logo
10:11 am - 2:48 pmGNV-TYS
4h 37m1 stop
Delta Logo
5:35 am - 9:26 amTYS-GNV
3h 51m1 stop
$464Delta
Find Deal
Sat, Nov 22 - Thu, Nov 27
Delta Logo
6:35 pm - 11:46 pmGNV-TYS
5h 11m1 stop
Delta Logo
5:44 am - 9:26 amTYS-GNV
3h 42m1 stop
$559Delta
Find Deal
Mon, Nov 3 - Fri, Nov 7
American Airlines Logo
6:45 pm - 10:51 pmGNV-TYS
4h 06m1 stop
American Airlines Logo
4:38 pm - 11:59 pmTYS-GNV
7h 21m2 stops
$701American Airlines
Find Deal
Mon, Nov 3 - Fri, Nov 7
American Airlines Logo
4:47 pm - 11:51 pmGNV-TYS
7h 04m1 stop
American Airlines Logo
7:48 am - 2:47 pmTYS-GNV
6h 59m2 stops
$780American Airlines
Find Deal
Sat, Nov 22 - Thu, Nov 27
American Airlines Logo
1:02 pm - 9:24 pmGNV-TYS
8h 22m2 stops
American Airlines Logo
4:38 pm - 11:59 pmTYS-GNV
7h 21m2 stops
$1,028American Airlines
Find Deal
Mon, Nov 3 - Fri, Nov 7

American Airlines flights from Gainesville to Knoxville

Our best American Airlines deals on Gainesville to Knoxville flight tickets
American Airlines
Nov 29
GNV5:33 pmGainesville Regional
6h 26m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
Dec 6
TYS9:04 amKnoxville McGhee Tyson
4h 23m
1 stop
GNV1:27 pmGainesville Regional
$348
Find similar
American Airlines
Nov 29
GNV5:33 pmGainesville Regional
6h 26m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
Dec 6
TYS2:55 pmKnoxville McGhee Tyson
9h 03m
2 stops
GNV11:58 pmGainesville Regional
$353
Find similar
American Airlines
Oct 29
GNV10:34 amGainesville Regional
6h 17m
1 stop
TYS4:51 pmKnoxville McGhee Tyson
Nov 3
TYS7:20 pmKnoxville McGhee Tyson
3h 59m
1 stop
GNV11:19 pmGainesville Regional
$426
Find similar

Delta flights from Gainesville to Knoxville

Our best Delta deals on Gainesville to Knoxville flight tickets
Delta
Nov 22
GNV10:11 amGainesville Regional
4h 37m
1 stop
TYS2:48 pmKnoxville McGhee Tyson
Nov 27
TYS5:35 amKnoxville McGhee Tyson
3h 51m
1 stop
GNV9:26 amGainesville Regional
$464
Find similar
Delta
Nov 3
GNV6:35 pmGainesville Regional
5h 11m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Nov 7
TYS5:44 amKnoxville McGhee Tyson
3h 42m
1 stop
GNV9:26 amGainesville Regional
$559
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 11/29

5:33 pm-11:59 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 12/6

9:04 am-1:27 pm

1 stop4h 23m

$348

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 11/29

5:33 pm-11:59 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 12/6

2:55 pm-11:58 pm

2 stops9h 03m

$353

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 11/22

10:11 am-2:48 pm

1 stop4h 37m

Knoxville McGhee Tyson

Thu 11/27

5:35 am-9:26 am

1 stop3h 51m

$464

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 11/3

6:35 pm-11:46 pm

1 stop5h 11m

Knoxville McGhee Tyson

Fri 11/7

5:44 am-9:26 am

1 stop3h 42m

$559

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 11/3

6:45 pm-10:51 pm

1 stop4h 06m

Knoxville McGhee Tyson

Fri 11/7

4:38 pm-11:59 pm

2 stops7h 21m

$701

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 11/22

4:47 pm-11:51 pm

1 stop7h 04m

Knoxville McGhee Tyson

Thu 11/27

7:48 am-2:47 pm

2 stops6h 59m

$780

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 11/3

1:02 pm-9:24 pm

2 stops8h 22m

Knoxville McGhee Tyson

Fri 11/7

4:38 pm-11:59 pm

2 stops7h 21m

$1,028

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 12/16

3:41 pm-8:05 pm

1 stop4h 24m

$189

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 11/18

6:00 am-2:52 pm

2 stops8h 52m

$194

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 12/18

3:41 pm-8:05 pm

1 stop4h 24m

$209

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Gainesville to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of September is, on average, the cheapest month to fly to Knoxville from Gainesville, with most prices found around $248. If you aren’t able to travel during the month of September, then book flights to Knoxville from Gainesville during August instead. Flights to Knoxville in August, while not as cheap as those in September, still average around $297.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Gainesville to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $454. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Gainesville to Knoxville for around $664.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Gainesville to Knoxville when you can find flight prices for as low as $463. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $684.

What is the cheapest Gainesville Regional to Knoxville McGhee Tyson flight route?

Fly from Gainesville Regional to Knoxville McGhee Tyson for the best Gainesville Regional - Knoxville McGhee Tyson flight prices

What cabin class options are available on Gainesville Regional to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Gainesville Regional to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Gainesville to Knoxville flights?

You could potentially save up to 41% on your flight if you consider stops on a Gainesville to Knoxville flight.

When to book flights from Gainesville to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Gainesville to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Gainesville to Knoxville (GNV to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gainesville to Knoxville

Direct flights

None
There are no direct flights from Gainesville to Knoxville. There are no popular flight routes from Gainesville to Knoxville.
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  • How far is Gainesville Regional to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 445.3 mi away from Gainesville Regional. Flights usually cover this in 4h 06m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Gainesville Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Gainesville Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Gainesville to Knoxville?

Best airlines flying from Gainesville to Knoxville

Compare and see reviews for airlines that fly from Gainesville to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.2
11,026 reviews
Search American Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.9
7,976 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Gainesville to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Gainesville.

Can I find flights from Gainesville to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Gainesville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Gainesville to Knoxville?

momondo helps you find the best flight between Gainesville and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Gainesville to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Gainesville to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.

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