What airlines fly to Des Moines?

Allegiant Air, Delta and American Airlines are the top three most popular airlines that fly to Des Moines from Gainesville according to our data. Allegiant Air is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 6 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?

Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?

As of October 2025, there are 2 operators available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.

How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$299 Cheap Flights from Gainesville to Des Moines in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Gainesville to Des Moines

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 2:08 pmGNV-DSM

9h 08m2 stops

5:34 am - 12:47 pmDSM-GNV

6h 13m1 stop

$352Delta

Find Deal

jue., nov. 27 - mié., dic. 3

3:02 pm - 11:59 pmGNV-DSM

9h 57m2 stops

5:39 am - 2:04 pmDSM-GNV

7h 25m1 stop

$397American Airlines

Find Deal

vie., oct. 31 - dom., nov. 2

6:00 am - 12:15 pmGNV-DSM

7h 15m1 stop

5:34 am - 12:47 pmDSM-GNV

6h 13m1 stop

$408Delta

Find Deal

jue., nov. 27 - mié., dic. 3

6:00 am - 2:08 pmGNV-DSM

9h 08m2 stops

2:59 pm - 11:11 pmDSM-GNV

7h 12m2 stops

$412Delta

Find Deal

jue., nov. 27 - mié., dic. 3

4:21 pm - 10:56 pmGNV-DSM

7h 35m1 stop

3:39 pm - 10:37 pmDSM-GNV

5h 58m1 stop

$434American Airlines

Find Deal

jue., oct. 30 - vie., nov. 7

6:00 am - 1:18 pmGNV-DSM

8h 18m2 stops

3:39 pm - 10:37 pmDSM-GNV

5h 58m1 stop

$439American Airlines

Find Deal

jue., oct. 30 - vie., nov. 7

10:34 am - 5:03 pmGNV-DSM

7h 29m1 stop

5:39 am - 12:23 pmDSM-GNV

5h 44m1 stop

$447American Airlines

Find Deal

vie., oct. 31 - dom., nov. 2

5:57 pm - 10:30 pmGNV-DSM

5h 33m1 stop

5:47 am - 12:47 pmDSM-GNV

6h 00m1 stop

$470Delta

Find Deal

sáb., oct. 18 - dom., oct. 19

3:02 pm - 11:59 pmGNV-DSM

9h 57m2 stops

5:00 am - 4:21 pmDSM-GNV

10h 21m2 stops

$471American Airlines

Find Deal

vie., oct. 31 - dom., nov. 2

4:21 pm - 11:16 pmGNV-DSM

7h 55m1 stop

5:39 am - 2:04 pmDSM-GNV

7h 25m1 stop

$501American Airlines

Find Deal

sáb., nov. 1 - dom., nov. 2

Delta flights from Gainesville to Des Moines

Our best Delta deals on Gainesville to Des Moines flight tickets

Delta

Nov 27

GNV6:00 amGainesville Regional

9h 08m

2 stops

DSM2:08 pmDes Moines

Dec 3

DSM5:34 amDes Moines

6h 13m

1 stop

GNV12:47 pmGainesville Regional

$352

Find similar

Delta

Nov 27

GNV6:00 amGainesville Regional

7h 15m

1 stop

DSM12:15 pmDes Moines

Dec 3

DSM5:34 amDes Moines

6h 13m

1 stop

GNV12:47 pmGainesville Regional

$408

Find similar

Delta

Nov 27

GNV6:00 amGainesville Regional

9h 08m

2 stops

DSM2:08 pmDes Moines

Dec 3

DSM2:59 pmDes Moines

7h 12m

2 stops

GNV11:11 pmGainesville Regional

$412

Find similar

American Airlines flights from Gainesville to Des Moines

Our best American Airlines deals on Gainesville to Des Moines flight tickets

American Airlines

Oct 31

GNV3:02 pmGainesville Regional

9h 57m

2 stops

DSM11:59 pmDes Moines

Nov 2

DSM5:39 amDes Moines

7h 25m

1 stop

GNV2:04 pmGainesville Regional

$397

Find similar

American Airlines

Oct 30

GNV4:21 pmGainesville Regional

7h 35m

1 stop

DSM10:56 pmDes Moines

Nov 7

DSM3:39 pmDes Moines

5h 58m

1 stop

GNV10:37 pmGainesville Regional

$434

Find similar

American Airlines

Oct 30

GNV6:00 amGainesville Regional

8h 18m

2 stops

DSM1:18 pmDes Moines

Nov 7

DSM3:39 pmDes Moines

5h 58m

1 stop

GNV10:37 pmGainesville Regional

$439

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

jue. 11/27

6:00 am-2:08 pm

2 stops9h 08m

Des Moines

mié. 12/3

5:34 am-12:47 pm

1 stop6h 13m

$352

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

vie. 10/31

3:02 pm-11:59 pm

2 stops9h 57m

Des Moines

dom. 11/2

5:39 am-2:04 pm

1 stop7h 25m

$397

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

jue. 11/27

6:00 am-12:15 pm

1 stop7h 15m

Des Moines

mié. 12/3

5:34 am-12:47 pm

1 stop6h 13m

$408

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

jue. 11/27

6:00 am-2:08 pm

2 stops9h 08m

Des Moines

mié. 12/3

2:59 pm-11:11 pm

2 stops7h 12m

$412

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

jue. 10/30

4:21 pm-10:56 pm

1 stop7h 35m

Des Moines

vie. 11/7

3:39 pm-10:37 pm

1 stop5h 58m

$434

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

jue. 10/30

6:00 am-1:18 pm

2 stops8h 18m

Des Moines

vie. 11/7

3:39 pm-10:37 pm

1 stop5h 58m

$439

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

vie. 10/31

10:34 am-5:03 pm

1 stop7h 29m

Des Moines

dom. 11/2

5:39 am-12:23 pm

1 stop5h 44m

$447

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

sáb. 10/18

5:57 pm-10:30 pm

1 stop5h 33m

Des Moines

dom. 10/19

5:47 am-12:47 pm

1 stop6h 00m

$470

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

vie. 10/31

3:02 pm-11:59 pm

2 stops9h 57m

Des Moines

dom. 11/2

5:00 am-4:21 pm

2 stops10h 21m

$471

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

sáb. 11/1

4:21 pm-11:16 pm

1 stop7h 55m

Des Moines

dom. 11/2

5:39 am-2:04 pm

1 stop7h 25m

$501

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Gainesville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Gainesville to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $376. Flights from Gainesville to Des Moines on a Wednesday will generally be more expensive and average around $543. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Gainesville to Des Moines in the afternoon for as low as $451. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $543. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Gainesville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Gainesville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Gainesville to Des Moines (GNV to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gainesville to Des Moines

Direct flights	None

There are no direct flights from Gainesville to Des Moines. There are no popular flight routes from Gainesville to Des Moines.

Search flight deals

How far is Gainesville Regional to Des Moines by plane?
Gainesville Regional and Des Moines are 1037.9 mi apart from one another. By plane, this route typically takes 5h 01m.
When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?
Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?
As of October 2025, there are 2 operators available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.
How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Gainesville to Des Moines?
Based on momondo bookings for flights between Gainesville and Des Moines, the leading airline is American Airlines, making up 58% of the total bookings. Other popular airlines include Delta with 42%.

Best airlines flying from Gainesville to Des Moines

Compare and see reviews for airlines that fly from Gainesville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $336	Free Cancellation	Rating 7.9 7,967 reviews		Search Delta flights
American Airlines	PriceFrom $363	Free Cancellation	Rating 7.2 11,040 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Pella

Newton

Johnston

Boone

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Gainesville to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Gainesville to Des Moines for you.

Can I find flights from Gainesville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Gainesville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Gainesville to Des Moines?

Once all potential Gainesville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Gainesville to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Gainesville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.