What airlines fly to Des Moines?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Gainesville according to our data. Allegiant Air is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 6 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Gainesville Regional to Des Moines?

Delta and American Airlines are the most popular carriers operating from Gainesville Regional to Des Moines

When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?

Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?

As of December 2025, there is 1 operator available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.

How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$264 Cheap Flights from Gainesville to Des Moines in 2025/26

1 adult

0 bags

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Find the cheapest flights from Gainesville to Des Moines

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Cheap round-trip flights

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4:30 pm - 11:23 pm

GNV

DSM

7h 53m1 stop

4:42 pm - 11:30 pm

DSM

GNV

5h 48m1 stop

$447American Airlines

Thu, Jan 8 - Sun, Jan 11

6:00 am - 3:15 pm

GNV

DSM

10h 15m2 stops

4:42 pm - 11:30 pm

DSM

GNV

5h 48m1 stop

$452American Airlines

Thu, Jan 8 - Sun, Jan 11

6:00 am - 5:06 pm

GNV

DSM

12h 06m2 stops

1:16 pm - 11:30 pm

DSM

GNV

9h 14m2 stops

$626American Airlines

Thu, Jan 8 - Sun, Jan 11

American Airlines flights from Gainesville to Des Moines

Our best American Airlines deals on Gainesville to Des Moines flight tickets

American Airlines

Jan 8

GNV4:30 pmGainesville Regional

7h 53m

1 stop

DSM11:23 pmDes Moines

Jan 11

DSM4:42 pmDes Moines

5h 48m

1 stop

GNV11:30 pmGainesville Regional

$447

Find similar

American Airlines

Jan 8

GNV6:00 amGainesville Regional

10h 15m

2 stops

DSM3:15 pmDes Moines

Jan 11

DSM4:42 pmDes Moines

5h 48m

1 stop

GNV11:30 pmGainesville Regional

$452

Find similar

American Airlines

Jan 8

GNV6:00 amGainesville Regional

12h 06m

2 stops

DSM5:06 pmDes Moines

Jan 11

DSM1:16 pmDes Moines

9h 14m

2 stops

GNV11:30 pmGainesville Regional

$626

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Thu 1/8

4:30 pm-11:23 pm

1 stop7h 53m

Des Moines

Sun 1/11

4:42 pm-11:30 pm

1 stop5h 48m

$447

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Thu 1/8

6:00 am-3:15 pm

2 stops10h 15m

Des Moines

Sun 1/11

4:42 pm-11:30 pm

1 stop5h 48m

$452

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Thu 1/8

6:00 am-5:06 pm

2 stops12h 06m

Des Moines

Sun 1/11

1:16 pm-11:30 pm

2 stops9h 14m

$626

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 3/17

6:00 am-10:39 am

1 stop5h 39m

$264

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 3/17

6:00 am-4:54 pm

2 stops11h 54m

$269

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Mon 1/5

6:30 am-1:21 pm

1 stop7h 51m

$274

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Mon 1/5

6:30 am-12:54 pm

2 stops7h 24m

$279

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sun 1/4

6:55 pm-10:29 pm

1 stop4h 34m

$304

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sun 1/4

6:30 am-2:53 pm

2 stops9h 23m

$433

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Gainesville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Gainesville to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $376. Flights from Gainesville to Des Moines on a Wednesday will generally be more expensive and average around $543. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Gainesville to Des Moines in the afternoon for as low as $451. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $543. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Gainesville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Gainesville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Gainesville to Des Moines (GNV to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gainesville to Des Moines

Fastest flight time	5h 02m
Direct flights	None

The fastest flight from Gainesville to Des Moines takes 5h 02m

There are no direct flights from Gainesville to Des Moines. There are no popular flight routes from Gainesville to Des Moines.

Search flight deals

How far is Gainesville Regional to Des Moines by plane?
Gainesville Regional and Des Moines are 1037.9 mi apart from one another. By plane, this route typically takes 5h 02m.
When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?
Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?
As of December 2025, there is 1 operator available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.
How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Gainesville to Des Moines?
Based on momondo bookings for flights between Gainesville and Des Moines, the leading airline is American Airlines, making up 100% of the total bookings.

Best airlines flying from Gainesville to Des Moines

Compare and see reviews for airlines that fly from Gainesville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $394	Free Cancellation	Rating 7.2 11,048 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Gainesville to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Gainesville to Des Moines for you.

Can I find flights from Gainesville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Gainesville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Gainesville to Des Moines?

Once all potential Gainesville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Gainesville to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Gainesville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.