What airlines fly to Des Moines?

Delta, Allegiant Air and American Airlines are the top three most popular airlines that fly to Des Moines from Gainesville according to our data. Delta is the first choice among our users, with 35% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 6 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?

Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?

As of July 2025, there are 2 operators available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.

How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$299 Cheap Flights from Gainesville to Des Moines in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Gainesville to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

4:24 pm - 11:13 pmGNV-DSM

7h 49m1 stop

4:09 pm - 10:36 pmDSM-GNV

5h 27m1 stop

$372American Airlines

Find Deal

Sat, Sep 13 - Mon, Sep 15

4:24 pm - 11:13 pmGNV-DSM

7h 49m1 stop

2:21 pm - 11:59 pmDSM-GNV

8h 38m2 stops

$377American Airlines

Find Deal

Sat, Sep 13 - Mon, Sep 15

10:52 am - 6:09 pmGNV-DSM

8h 17m2 stops

1:40 pm - 11:59 pmDSM-GNV

9h 19m2 stops

$382American Airlines

Find Deal

Sat, Sep 13 - Mon, Sep 15

7:06 pm - 10:37 pmGNV-DSM

4h 31m1 stop

5:44 am - 12:31 pmDSM-GNV

5h 47m1 stop

$407Delta

Find Deal

Fri, Sep 19 - Mon, Sep 22

7:07 pm - 10:43 pmGNV-DSM

4h 36m1 stop

6:05 am - 2:59 pmDSM-GNV

7h 54m2 stops

$425Delta

Find Deal

Mon, Oct 13 - Wed, Oct 15

11:17 am - 4:48 pmGNV-DSM

6h 31m1 stop

6:12 pm - 12:09 amDSM-GNV

4h 57m1 stop

$441American Airlines

Find Deal

Wed, Aug 13 - Sun, Aug 17

6:00 am - 2:40 pmGNV-DSM

9h 40m2 stops

6:12 pm - 12:09 amDSM-GNV

4h 57m1 stop

$446American Airlines

Find Deal

Wed, Aug 13 - Sun, Aug 17

7:06 pm - 10:37 pmGNV-DSM

4h 31m1 stop

6:00 am - 3:16 pmDSM-GNV

8h 16m2 stops

$488Delta

Find Deal

Fri, Sep 19 - Mon, Sep 22

6:01 am - 3:18 pmGNV-DSM

10h 17m2 stops

5:12 am - 4:30 pmDSM-GNV

10h 18m2 stops

$580American Airlines

Find Deal

Wed, Aug 13 - Sun, Aug 17

7:07 pm - 10:43 pmGNV-DSM

4h 36m1 stop

10:52 am - 6:22 pmDSM-GNV

6h 30m1 stop

$750Delta

Find Deal

Mon, Oct 13 - Wed, Oct 15

American Airlines flights from Gainesville to Des Moines

Our best American Airlines deals on Gainesville to Des Moines flight tickets

American Airlines

Sep 13

GNV4:24 pmGainesville Regional

7h 49m

1 stop

DSM11:13 pmDes Moines

Sep 15

DSM4:09 pmDes Moines

5h 27m

1 stop

GNV10:36 pmGainesville Regional

$372

Find similar

American Airlines

Sep 13

GNV4:24 pmGainesville Regional

7h 49m

1 stop

DSM11:13 pmDes Moines

Sep 15

DSM2:21 pmDes Moines

8h 38m

2 stops

GNV11:59 pmGainesville Regional

$377

Find similar

American Airlines

Sep 13

GNV10:52 amGainesville Regional

8h 17m

2 stops

DSM6:09 pmDes Moines

Sep 15

DSM1:40 pmDes Moines

9h 19m

2 stops

GNV11:59 pmGainesville Regional

$382

Find similar

Delta flights from Gainesville to Des Moines

Our best Delta deals on Gainesville to Des Moines flight tickets

Delta

Sep 19

GNV7:06 pmGainesville Regional

4h 31m

1 stop

DSM10:37 pmDes Moines

Sep 22

DSM5:44 amDes Moines

5h 47m

1 stop

GNV12:31 pmGainesville Regional

$407

Find similar

Delta

Oct 13

GNV7:07 pmGainesville Regional

4h 36m

1 stop

DSM10:43 pmDes Moines

Oct 15

DSM6:05 amDes Moines

7h 54m

2 stops

GNV2:59 pmGainesville Regional

$425

Find similar

Delta

Sep 19

GNV7:06 pmGainesville Regional

4h 31m

1 stop

DSM10:37 pmDes Moines

Sep 22

DSM6:00 amDes Moines

8h 16m

2 stops

GNV3:16 pmGainesville Regional

$488

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 9/13

4:24 pm-11:13 pm

1 stop7h 49m

Des Moines

Mon 9/15

4:09 pm-10:36 pm

1 stop5h 27m

$372

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 9/13

4:24 pm-11:13 pm

1 stop7h 49m

Des Moines

Mon 9/15

2:21 pm-11:59 pm

2 stops8h 38m

$377

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 9/13

10:52 am-6:09 pm

2 stops8h 17m

Des Moines

Mon 9/15

1:40 pm-11:59 pm

2 stops9h 19m

$382

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Fri 9/19

7:06 pm-10:37 pm

1 stop4h 31m

Des Moines

Mon 9/22

5:44 am-12:31 pm

1 stop5h 47m

$407

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Mon 10/13

7:07 pm-10:43 pm

1 stop4h 36m

Des Moines

Wed 10/15

6:05 am-2:59 pm

2 stops7h 54m

$425

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Wed 8/13

11:17 am-4:48 pm

1 stop6h 31m

Des Moines

Sun 8/17

6:12 pm-12:09 am

1 stop4h 57m

$441

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Wed 8/13

6:00 am-2:40 pm

2 stops9h 40m

Des Moines

Sun 8/17

6:12 pm-12:09 am

1 stop4h 57m

$446

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Fri 9/19

7:06 pm-10:37 pm

1 stop4h 31m

Des Moines

Mon 9/22

6:00 am-3:16 pm

2 stops8h 16m

$488

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Wed 8/13

6:01 am-3:18 pm

2 stops10h 17m

Des Moines

Sun 8/17

5:12 am-4:30 pm

2 stops10h 18m

$580

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Mon 10/13

7:07 pm-10:43 pm

1 stop4h 36m

Des Moines

Wed 10/15

10:52 am-6:22 pm

1 stop6h 30m

$750

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Gainesville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Gainesville to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $376. Flights from Gainesville to Des Moines on a Wednesday will generally be more expensive and average around $543. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Gainesville to Des Moines in the afternoon for as low as $451. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $543. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Gainesville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Gainesville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Gainesville to Des Moines (GNV to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Gainesville to Des Moines

Best Price Found	$372
Fastest flight time	4h 31m
Direct flights	None
Airports in Des Moines	1 airport

The best flight deal from Gainesville to Des Moines found on momondo in the last 72 hours is $372

The fastest flight from Gainesville to Des Moines takes 4h 31m

There are no direct flights from Gainesville to Des Moines. Popular non-direct route for this connection is Gainesville Regional Airport - Des Moines Airport.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Gainesville Regional to Des Moines by plane?
Gainesville Regional and Des Moines are 1037.9 mi apart from one another. By plane, this route typically takes 4h 31m.
When did momondo last update prices for flights from Gainesville Regional Airport to Des Moines Airport?
Prices for flights from Gainesville Regional Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Gainesville Regional Airport to Des Moines Airport?
As of July 2025, there are 2 operators available to choose from for flights from Gainesville Regional Airport to Des Moines Airport.
How old do you have to be to fly from Gainesville Regional Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Gainesville Regional Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Gainesville to Des Moines?
Based on momondo bookings for flights between Gainesville and Des Moines, the leading airline is American Airlines, making up 51% of the total bookings. Other popular airlines include Delta with 49%.

Best airlines flying from Gainesville to Des Moines

Compare and see reviews for airlines that fly from Gainesville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $306	Free Cancellation	Rating 8.0 7,981 reviews		Search Delta flights
American Airlines	PriceFrom $363	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Newton

Pella

Boone

Johnston

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Gainesville to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Gainesville to Des Moines for you.

Can I find flights from Gainesville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Gainesville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Gainesville to Des Moines?

Once all potential Gainesville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Gainesville to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Gainesville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.