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Cheap flights from Florida Keys to South Carolina from $43

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florida Keys to South Carolina departing on 11/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Florida Keys to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:38 pm - 9:57 pmMIA-CLT
2h 19mnonstop
Frontier Logo
3:42 pm - 5:55 pmCLT-MIA
2h 13mnonstop
$80Frontier
Find Deal
Mon, Nov 17 - Thu, Dec 4
Spirit Airlines Logo
5:45 am - 7:47 amMIA-CLT
2h 02mnonstop
Spirit Airlines Logo
7:59 pm - 10:11 pmCLT-MIA
2h 12mnonstop
$81Spirit Airlines
Find Deal
Mon, Nov 17 - Tue, Nov 18
Multiple Airlines Logo
7:38 pm - 9:57 pmMIA-CLT
2h 19mnonstop
Multiple Airlines Logo
7:59 pm - 10:11 pmCLT-MIA
2h 12mnonstop
$91Multiple Airlines
Find Deal
Fri, Nov 14 - Tue, Nov 18
Multiple Airlines Logo
5:45 am - 7:47 amMIA-CLT
2h 02mnonstop
Multiple Airlines Logo
10:42 pm - 12:54 amCLT-MIA
2h 12mnonstop
$96Multiple Airlines
Find Deal
Sat, Nov 15 - Sun, Nov 16
American Airlines Logo
11:03 pm - 12:46 amMIA-CHS
1h 43mnonstop
American Airlines Logo
6:00 am - 7:44 amCHS-MIA
1h 44mnonstop
$97American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
10:08 pm - 11:55 pmMIA-CHS
1h 47mnonstop
American Airlines Logo
7:28 pm - 9:25 pmCHS-MIA
1h 57mnonstop
$117American Airlines
Find Deal
Sat, Jan 10 - Sun, Jan 11
Southwest Logo
1:30 pm - 7:55 pmMIA-CHS
6h 25m1 stop
Southwest Logo
10:35 am - 4:10 pmCHS-MIA
5h 35m1 stop
$151Southwest
Find Deal
Wed, Dec 3 - Wed, Dec 10
Delta Logo
3:50 pm - 8:34 pmMIA-CHS
4h 44m1 stop
Delta Logo
6:31 pm - 12:46 amCHS-MIA
6h 15m1 stop
$157Delta
Find Deal
Thu, Dec 4 - Mon, Dec 8
Delta Logo
5:00 pm - 11:59 pmMIA-SAV
6h 59m1 stop
Delta Logo
6:41 am - 11:21 amSAV-MIA
4h 40m1 stop
$179Delta
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Tue, Dec 2 - Tue, Dec 9
Southwest Logo
7:40 am - 12:25 pmMIA-CHS
4h 45m1 stop
Southwest Logo
10:35 am - 9:50 pmCHS-MIA
11h 15m2 stops
$214Southwest
Find Deal
Wed, Dec 3 - Wed, Dec 10

Spirit Airlines flights from Florida Keys to South Carolina

Our best Spirit Airlines deals on Florida Keys to South Carolina flight tickets
Spirit Airlines
Nov 7
MIA5:45 amMiami
2h 02m
CLT7:47 amCharlotte Douglas
Nov 9
CLT9:38 pmCharlotte Douglas
2h 13m
MIA11:51 pmMiami
$79
Find similar
Spirit Airlines
Nov 17
MIA5:45 amMiami
2h 02m
CLT7:47 amCharlotte Douglas
Nov 18
CLT7:59 pmCharlotte Douglas
2h 12m
MIA10:11 pmMiami
$81
Find similar
Spirit Airlines
Nov 21
MIA6:46 amMiami
2h 03m
CLT8:49 amCharlotte Douglas
Nov 23
CLT8:52 pmCharlotte Douglas
2h 12m
MIA11:04 pmMiami
$82
Find similar

Frontier flights from Florida Keys to South Carolina

Our best Frontier deals on Florida Keys to South Carolina flight tickets
Frontier
Nov 17
MIA7:38 pmMiami
2h 19m
CLT9:57 pmCharlotte Douglas
Dec 4
CLT3:42 pmCharlotte Douglas
2h 13m
MIA5:55 pmMiami
$80
Find similar
Frontier
Nov 21
MIA7:00 amMiami
2h 18m
CLT9:18 amCharlotte Douglas
Nov 24
CLT10:04 amCharlotte Douglas
2h 06m
MIA12:10 pmMiami
$83
Find similar
Frontier
Nov 7
MIA7:38 pmMiami
2h 19m
CLT9:57 pmCharlotte Douglas
Nov 9
CLT10:42 pmCharlotte Douglas
2h 12m
MIA12:54 amMiami
$85
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florida Keys to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Florida Keys to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Mon 11/17

7:38 pm-9:57 pm

Nonstop2h 19m

Charlotte Douglas

Thu 12/4

3:42 pm-5:55 pm

Nonstop2h 13m

$80

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Mon 11/17

5:45 am-7:47 am

Nonstop2h 02m

Charlotte Douglas

Tue 11/18

7:59 pm-10:11 pm

Nonstop2h 12m

$81

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Fri 11/14

7:38 pm-9:57 pm

Nonstop2h 19m

Charlotte Douglas

Tue 11/18

7:59 pm-10:11 pm

Nonstop2h 12m

$91

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Sat 11/15

5:45 am-7:47 am

Nonstop2h 02m

Charlotte Douglas

Sun 11/16

10:42 pm-12:54 am

Nonstop2h 12m

$96

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 12/4

11:03 pm-12:46 am

Nonstop1h 43m

Charleston

Sun 12/7

6:00 am-7:44 am

Nonstop1h 44m

$97

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 1/10

10:08 pm-11:55 pm

Nonstop1h 47m

Charleston

Sun 1/11

7:28 pm-9:25 pm

Nonstop1h 57m

$117

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 12/3

1:30 pm-7:55 pm

1 stop6h 25m

Charleston

Wed 12/10

10:35 am-4:10 pm

1 stop5h 35m

$151

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 12/4

3:50 pm-8:34 pm

1 stop4h 44m

Charleston

Mon 12/8

6:31 pm-12:46 am

1 stop6h 15m

$157

MiamiSavannah

MIA - SAV

MIASAV

Miami

Tue 12/2

5:00 pm-11:59 pm

1 stop6h 59m

Savannah/Hilton Head

Tue 12/9

6:41 am-11:21 am

1 stop4h 40m

$179

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 12/3

7:40 am-12:25 pm

1 stop4h 45m

Charleston

Wed 12/10

10:35 am-9:50 pm

2 stops11h 15m

$214

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Florida Keys to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Florida Keys is in January. Flight prices, which tend to average around $232, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Florida Keys during December instead. Flights to South Carolina in December, while not as cheap as those in January, still average around $238.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $538. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $616.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Florida Keys to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $518. Try not to purchase tickets in the morning because they tend to be around $571. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Florida Keys when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $260 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Florida Keys for as low as $178 on momondo.

Can stopping save me money on Florida Keys to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Florida Keys to South Carolina.

Cheap Florida Keys to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florida Keys to South Carolina

Fastest flight time

1h 34m

Direct flights

Every day

Airports in South Carolina

4 airports
The fastest flight from Florida Keys to South Carolina takes 1h 34m
Direct flights go from Florida Keys to South Carolina every day.
There are 4 airports near South Carolina: Greenville (GSP), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)
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  • When did momondo last update prices for flights from Florida Keys to South Carolina?

    Prices for flights from Florida Keys to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Florida Keys to South Carolina?

  • How old do you have to be to fly from Florida Keys to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florida Keys to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Florida Keys to South Carolina?

Best airlines flying from Florida Keys to South Carolina

Compare and see reviews for airlines that fly from Florida Keys to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,003 reviews
Search Delta flights
American AirlinesPriceFrom $387Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Florida Keys to South Carolina?

It is quick and easy to find Florida Keys to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Florida Keys to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Florida Keys on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Florida Keys to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Florida Keys. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Florida Keys to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florida Keys to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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