Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Florida Keys to South Carolina from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florida Keys to South Carolina departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Florida Keys to South Carolina

Cheap round-trip flights

Frontier Logo
4:21 pm - 6:34 pmMIA-CLT
2h 13mnonstop
Frontier Logo
7:29 pm - 9:41 pmCLT-MIA
2h 12mnonstop
$88Frontier
Find Deal
Mon, Oct 13 - Mon, Oct 20
Multiple Airlines Logo
6:00 am - 8:11 amMIA-CLT
2h 11mnonstop
Multiple Airlines Logo
1:49 pm - 3:53 pmCLT-MIA
2h 04mnonstop
$91Multiple Airlines
Find Deal
Mon, Oct 6 - Sat, Oct 11
Spirit Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
Spirit Airlines Logo
1:49 pm - 3:53 pmCLT-MIA
2h 04mnonstop
$97Spirit Airlines
Find Deal
Thu, Oct 16 - Sun, Oct 19
Spirit Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
Spirit Airlines Logo
10:32 am - 12:51 pmCLT-MIA
2h 19mnonstop
$107Spirit Airlines
Find Deal
Thu, Oct 23 - Mon, Jan 12
American Airlines Logo
7:05 am - 8:47 amMIA-CHS
1h 42mnonstop
American Airlines Logo
7:54 pm - 9:44 pmCHS-MIA
1h 50mnonstop
$147American Airlines
Find Deal
Fri, Dec 5 - Wed, Dec 10
American Airlines Logo
9:46 pm - 11:37 pmMIA-CHS
1h 51mnonstop
American Airlines Logo
7:44 pm - 9:26 pmCHS-MIA
1h 42mnonstop
$157American Airlines
Find Deal
Thu, Oct 2 - Mon, Oct 6
Southwest Logo
6:00 am - 2:10 pmMIA-CHS
8h 10m1 stop
Southwest Logo
6:00 am - 12:50 pmCHS-MIA
6h 50m1 stop
$167Southwest
Find Deal
Fri, Dec 12 - Mon, Dec 15
Southwest Logo
9:30 am - 8:35 pmMIA-CHS
11h 05m1 stop
Southwest Logo
10:35 am - 4:10 pmCHS-MIA
5h 35m1 stop
$172Southwest
Find Deal
Fri, Dec 5 - Wed, Dec 10
Delta Logo
6:00 am - 11:46 amMIA-CHS
5h 46m1 stop
Delta Logo
8:10 am - 12:57 pmCHS-MIA
4h 47m1 stop
$177Delta
Find Deal
Tue, Oct 14 - Tue, Oct 21
Delta Logo
10:28 am - 3:38 pmMIA-CHS
5h 10m1 stop
Delta Logo
5:35 pm - 9:23 pmCHS-MIA
3h 48m1 stop
$194Delta
Find Deal
Tue, Sep 30 - Sat, Oct 4

Spirit Airlines flights from Florida Keys to South Carolina

Our best Spirit Airlines deals on Florida Keys to South Carolina flight tickets
Spirit Airlines
Oct 16
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
Oct 19
CLT1:49 pmCharlotte Douglas
2h 04m
MIA3:53 pmMiami
$97
Find similar
Spirit Airlines
Oct 23
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
Jan 12
CLT10:32 amCharlotte Douglas
2h 19m
MIA12:51 pmMiami
$107
Find similar
Spirit Airlines
Oct 25
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
Oct 27
CLT1:49 pmCharlotte Douglas
2h 04m
MIA3:53 pmMiami
$109
Find similar

Frontier flights from Florida Keys to South Carolina

Our best Frontier deals on Florida Keys to South Carolina flight tickets
Frontier
Oct 13
MIA4:21 pmMiami
2h 13m
CLT6:34 pmCharlotte Douglas
Oct 20
CLT7:29 pmCharlotte Douglas
2h 12m
MIA9:41 pmMiami
$88
Find similar
Frontier
Oct 25
MIA7:32 pmMiami
12h 21m
1 stop
CLT7:53 amCharlotte Douglas
Oct 26
CLT7:24 pmCharlotte Douglas
2h 12m
MIA9:36 pmMiami
$92
Find similar
Frontier
Oct 17
MIA4:16 pmMiami
2h 13m
CLT6:29 pmCharlotte Douglas
Oct 19
CLT7:24 pmCharlotte Douglas
2h 12m
MIA9:36 pmMiami
$93
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florida Keys to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Florida Keys to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Mon 10/13

4:21 pm-6:34 pm

Nonstop2h 13m

Charlotte Douglas

Mon 10/20

7:29 pm-9:41 pm

Nonstop2h 12m

$88

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Mon 10/6

6:00 am-8:11 am

Nonstop2h 11m

Charlotte Douglas

Sat 10/11

1:49 pm-3:53 pm

Nonstop2h 04m

$91

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Thu 10/16

10:24 am-12:39 pm

Nonstop2h 15m

Charlotte Douglas

Sun 10/19

1:49 pm-3:53 pm

Nonstop2h 04m

$97

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Thu 10/23

10:24 am-12:39 pm

Nonstop2h 15m

Charlotte Douglas

Mon 1/12

10:32 am-12:51 pm

Nonstop2h 19m

$107

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/5

7:05 am-8:47 am

Nonstop1h 42m

Charleston

Wed 12/10

7:54 pm-9:44 pm

Nonstop1h 50m

$147

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 10/2

9:46 pm-11:37 pm

Nonstop1h 51m

Charleston

Mon 10/6

7:44 pm-9:26 pm

Nonstop1h 42m

$157

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/12

6:00 am-2:10 pm

1 stop8h 10m

Charleston

Mon 12/15

6:00 am-12:50 pm

1 stop6h 50m

$167

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/5

9:30 am-8:35 pm

1 stop11h 05m

Charleston

Wed 12/10

10:35 am-4:10 pm

1 stop5h 35m

$172

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/14

6:00 am-11:46 am

1 stop5h 46m

Charleston

Tue 10/21

8:10 am-12:57 pm

1 stop4h 47m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 9/30

10:28 am-3:38 pm

1 stop5h 10m

Charleston

Sat 10/4

5:35 pm-9:23 pm

1 stop3h 48m

$194

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to South Carolina from

How to get the cheapest flight ticket from Florida Keys to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Florida Keys is in September. Flight prices, which tend to average around $229, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Florida Keys during August instead. Flights to South Carolina in August, while not as cheap as those in September, still average around $237.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $538. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $616.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Florida Keys to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $518. Try not to purchase tickets in the morning because they tend to be around $571. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Florida Keys when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $261 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Florida Keys for as low as $178 on momondo.

Can stopping save me money on Florida Keys to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Florida Keys to South Carolina.

Cheap Florida Keys to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florida Keys to South Carolina

Fastest flight time

1h 29m

Direct flights

Every day

Airports in South Carolina

2 airports
The fastest flight from Florida Keys to South Carolina takes 1h 29m
Direct flights go from Florida Keys to South Carolina every day.
There are 2 airports near South Carolina: Savannah/Hilton Head (SAV), Charleston (CHS)
Search flight deals

  • When did momondo last update prices for flights from Florida Keys to South Carolina?

    Prices for flights from Florida Keys to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Florida Keys to South Carolina?

  • How old do you have to be to fly from Florida Keys to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florida Keys to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Florida Keys to South Carolina?

Best airlines flying from Florida Keys to South Carolina

Compare and see reviews for airlines that fly from Florida Keys to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
7,961 reviews
Search Delta flights
American AirlinesPriceFrom $293Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Florida Keys to South Carolina?

It is quick and easy to find Florida Keys to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Florida Keys to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Florida Keys on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Florida Keys to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Florida Keys. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Florida Keys to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florida Keys to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 10/17
Fri 10/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $49
Flights to Los Angelesfrom $49
Flights to Miamifrom $49
Flights to Chicagofrom $49
Flights to Orlandofrom $60
Flights to Las Vegasfrom $48
Flights to San Franciscofrom $53
Flights to Washington, D.C.from $49
Flights to Bostonfrom $62
Flights to Atlantafrom $51
Flights to Dallasfrom $68
Flights to Seattlefrom $69