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Cheap flights from Florence, South Carolina to Lexington from $503

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Lexington departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Florence, South Carolina to Lexington

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:15 am - 12:09 pm
FLO
-
LEX
5h 54m
1 stop
American Airlines Logo
1:14 pm - 5:50 pm
LEX
-
FLO
4h 36m
1 stop
$541American Airlines
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
6:15 am - 3:51 pm
FLO
-
LEX
9h 36m
2 stops
American Airlines Logo
1:14 pm - 5:50 pm
LEX
-
FLO
4h 36m
1 stop
$546American Airlines
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
6:15 am - 3:51 pm
FLO
-
LEX
9h 36m
2 stops
American Airlines Logo
4:59 pm - 11:57 pm
LEX
-
FLO
6h 58m
2 stops
$601American Airlines
Tue, Mar 31 - Sat, Apr 4

American Airlines flights from Florence, South Carolina to Lexington

Our best American Airlines deals on Florence, South Carolina to Lexington flight tickets
American Airlines
Mar 31
FLO6:15 amFlorence
5h 54m
1 stop
LEX12:09 pmLexington Blue Grass
Apr 4
LEX1:14 pmLexington Blue Grass
4h 36m
1 stop
FLO5:50 pmFlorence
$541
American Airlines
Mar 31
FLO6:15 amFlorence
9h 36m
2 stops
LEX3:51 pmLexington Blue Grass
Apr 4
LEX1:14 pmLexington Blue Grass
4h 36m
1 stop
FLO5:50 pmFlorence
$546
American Airlines
Mar 31
FLO6:15 amFlorence
9h 36m
2 stops
LEX3:51 pmLexington Blue Grass
Apr 4
LEX4:59 pmLexington Blue Grass
6h 58m
2 stops
FLO11:57 pmFlorence
$601

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Florence, South Carolina to Lexington that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Tue 3/31

6:15 am-12:09 pm

1 stop5h 54m

Lexington Blue Grass

Sat 4/4

1:14 pm-5:50 pm

1 stop4h 36m

$541

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Tue 3/31

6:15 am-3:51 pm

2 stops9h 36m

Lexington Blue Grass

Sat 4/4

1:14 pm-5:50 pm

1 stop4h 36m

$546

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Tue 3/31

6:15 am-3:51 pm

2 stops9h 36m

Lexington Blue Grass

Sat 4/4

4:59 pm-11:57 pm

2 stops6h 58m

$601
Cheapest one-way
Quickest one-way

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Mon 3/23

6:20 pm-9:50 pm

1 stop3h 30m

$503

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Mon 3/23

6:20 pm-9:50 pm

1 stop3h 30m

$540

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Mon 3/23

6:20 pm-9:24 am

2 stops15h 04m

$803

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Mon 3/23

6:20 pm-9:24 am

2 stops15h 04m

$813

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Lexington from

How to get the cheapest flight ticket from Florence, South Carolina to Lexington

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Florence to Lexington Blue Grass?

American Airlines is the most popular carrier operating from Florence to Lexington Blue Grass

What airlines fly to Lexington?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Lexington from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Lexington. Keep in mind that there are 6 different airlines that fly to Lexington on a routine basis, so you have a few additional options to choose from.

When to book flights from Florence, South Carolina to Lexington

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Lexington according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to Lexington (FLO to LEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Lexington

Fastest flight time

5h 54m

Direct flights

None
The fastest flight from Florence, South Carolina to Lexington takes 5h 54m
There are no direct flights from Florence, South Carolina to Lexington. There are no popular flight routes from Florence, South Carolina to Lexington.
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  • How far is Florence to Lexington Blue Grass by plane?

    The straight-line distance from Florence to Lexington Blue Grass is 374.3 mi. Typically, this will take 5h 54m by plane in normal conditions.

  • When did momondo last update prices for flights from Florence Airport to Lexington Blue Grass Airport?

    Prices for flights from Florence Airport to Lexington Blue Grass Airport refresh daily.

  • How old do you have to be to fly from Florence Airport to Lexington Blue Grass Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Lexington Blue Grass Airport.

  • What documentation or ID do you need to fly to Lexington Blue Grass Airport?

    The required travel and health documents for your Lexington Blue Grass Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lexington Blue Grass Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Richmond
Somerset
Georgetown
Danville
Frankfort
Winchester
Berea
Versailles
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Lexington?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Florence to Lexington. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Florence to Lexington with flexible booking policies on momondo?

Flights from Florence to Lexington with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Florence to Lexington?

Once you have performed a search for Florence to Lexington flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Florence to Lexington right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florence to Lexington flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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