Cheap flights from District of Columbia to Missouri from $122

In general, December is the cheapest month to fly from District of Columbia to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $78. If you aren’t able to travel to Missouri during the month of December, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $90.

The cheapest day to depart from District of Columbia to Missouri is on a Saturday when prices can be found for as low as $407. Flights from District of Columbia to Missouri on a Monday will generally be more expensive and average around $749. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is in the morning. momondo users have found flights departing from District of Columbia to Missouri in the morning for as low as $512. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $617. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Baltimore/Washington to Lambert-St Louis for the best District of Columbia - Missouri flight prices

You are more likely to see cheaper flights to Missouri from District of Columbia when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $427 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from District of Columbia for as low as $124 on momondo.

There are 4 cabin classes available to choose from on District of Columbia to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Frontier, and Delta are the most popular carriers operating from District of Columbia to Missouri

Southwest, American Airlines and United Airlines are the top three most popular airlines that fly to Missouri from District of Columbia according to our data. Southwest is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 6 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of June 2026, there are 23 flights per day flying from District of Columbia to Missouri. The most common time of day flights depart is 5:00PM, with 59% of flights taking off in the afternoon.

As of June 2026, 161 flights take off from District of Columbia and land in Missouri each week. The most common flight departure day for this route is Mon, with 19% of weekly flights taking off on this day.